STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

View: E.coli K-12 (MG1655) Secretome  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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E.coli K-12 (MG1655) Secretome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
(Uniprot)
Order
Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
EchoLOCATION
Extracellular Appendage
First Level
Targeting
Chaperoning
First Level
Secretion
System
Second Level
Targeting
Chaperoning
Second Level
Secretion
System
K-12 Core
Proteome
(yes/no)
K-12 Basic
Proteome
(yes/no)
FLIY_ECOLI
P0AEM9
fliY

yzzR

b1920 JW1905
periplasmic protein (SEC through IM), L-cystine-binding FliY
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
no
yes
FTSL_ECOLI
P0AEN4
ftsL

mraR yabD

b0083 JW0081
IM lipoprotein (SEC through IM), Cell division FtsL
Inner Membrane Lipoprotein
E
IM (predicted)
Cell inner membrane
Membrane anchored (Experimental)
 
 
SEC
 
 
yes
yes
GLNH_ECOLI
P0AEQ3
glnH
b0811 JW0796
periplasmic protein (SEC through IM), Glutamine-binding periplasmic GlnH
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
SURA
 
yes
yes
HDEA_ECOLI
P0AES9
hdeA

yhhC yhiB

b3510 JW3478
periplasmic protein (SEC through IM), Acid stress chaperone HdeA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
YfgM
 
yes
yes
HDEB_ECOLI
P0AET2
hdeB

yhhD yhiC

b3509 JW5669
periplasmic protein (SEC through IM), Acid stress chaperone HdeB
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
YfgM
 
yes
yes
HISJ_ECOLI
P0AEU0
hisJ
b2309 JW2306
periplasmic protein (SEC through IM), Histidine-binding periplasmic HisJ
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
DSBA
 
yes
yes
SKP_ECOLI
P0AEU7
skp

hlpA ompH

b0178 JW0173
periplasmic protein (SEC through IM), Chaperone Skp
Periplasmic
G
N/A
Periplasm
Periplasmic(experimental)
 
 
SEC
 
 
yes
yes
MALE_ECOLI
P0AEX9
malE
b4034 JW3994
periplasmic & peripheral IM protein (SEC through IM), Maltose/maltodextrin-binding periplasmic MalE
Peripheral inner membrane protein facing the periplasm, periplasmic
F2, G
N/A
Periplasm
Periplasmic (Experimental)
 
SecB
SEC
SURA,SKP,YfgM
 
yes
yes
MLTD_ECOLI
P0AEZ7
mltD

dniR yafG

b0211 JW5018
OM lipoprotein (SEC through IM), inserted in OM by LOL), Membrane-bound lytic murein transglycosylase D MltD
Outer Membrane Lipoprotein
I
N/A
Cell membrane
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
YJBE_ECOLI
P0AF45
yjbE
b4026 JW3986
periplasmic protein (SEC through IM), YjbE
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
no
yes
YJCO_ECOLI
P0AF56
yjcO
b4078 JW4039
periplasmic protein (SEC through IM), Sel1-repeat-containing YjcO
Periplasmic
G
N/A
 
Periplasmic
 
 
SEC
 
 
yes
yes
YJEI_ECOLI
P0AF70
yjeI
b4144 JW5736
OM lipoprotein (SEC through IM, inserted in OM by LOL), YjeI
Outer Membrane Lipoprotein
I
Soluble IM Fraction
 
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
YJFN_ECOLI
P0AF82
yjfN
b4188 JW5742
periplasmic protein (SEC through IM), YjfN
Periplasmic
G
N/A
Periplasm
Periplasmic
 
 
SEC
 
 
yes
yes
YJFY_ECOLI
P0AF86
yjfY
b4199 JW4157
periplasmic protein (SEC through IM), YjfY
Periplasmic
G
N/A
Periplasm
Periplasmic
 
 
SEC
 
 
yes
yes
NLPI_ECOLI
P0AFB1
nlpI

yhbM

b3163 JW3132
OM lipoprotein (SEC through IM, inserted in OM by LOL), NlpI
Outer Membrane Lipoprotein
I
N/A
Cell membrane; Lipid-anchor
Outer membrane Lipoprotein (Experimental)
 
 
SEC
 
LOL
yes
yes
OSMY_ECOLI
P0AFH8
osmY
b4376 JW4338
periplasmic & extra-cellular protein (SEC through IM), Osmotically-inducible Y OsmY
Periplasmic, Extra-cellular
G, X
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
PBP7_ECOLI
P0AFI5
pbpG

yohB

b2134 JW5355
periplasmic protein (SEC through IM), D-alanyl-D-alanine endopeptidase PbpG
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
POTD_ECOLI
P0AFK9
potD
b1123 JW1109
periplasmic protein (SEC through IM), Spermidine/putrescine-binding periplasmic PotD
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
PPIA_ECOLI
P0AFL3
ppiA

rot rotA

b3363 JW3326
periplasmic protein (SEC through IM), Peptidyl-prolyl cis-trans isomerase A PpiA
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
 
 
yes
yes
PROX_ECOLI
P0AFM2
proX

proU

b2679 JW2654
periplasmic protein (SEC through IM), Glycine betaine/proline betaine-binding periplasmic ProX
Periplasmic
G
N/A
Periplasm
Periplasmic (Experimental)
 
 
SEC
SURA,DSBA
 
yes
yes
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