| entry | acc | gene | alt_gene | oln | protein_name | cm_loca | cm_notes | cm_refs | suboci_full | subloci | subloci_iim | nterm_cterm | bernsel | subloci_uniprot | subloci_echoL | organelle | target_chaperoning1 | 1st_ss | target_chaperoning2 | 2nd_ss | pseudo | common_core | basic_proteome | signalp_sp_exist | signalp_pos | signalp_cmax | lipop_pred | lipop_cleavage | lipop_score | lipop_rule | tmhmm | phobius_tms | phobius_sp_exist | phobius_prediction | psortb_loca | psortb_score | solubility |
| YKFM_ECOLI | A5A605 | ykfM | b4586 | integral IM protein (SEC in IM), YkfM | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Membrane | - | SRP | SEC | no | yes | N | 27 | 0.205 | TMH | 0 | 13.6098 | - | 3 | 3 | N | i12-32o52-75i96-119o | CytoplasmicMembrane | 10 | |||||||||
| YNCL_ECOLI | A5A615 | yncL | b4598 JW1439.1 | integral IM protein (SEC in IM), YncL | Integral Inner Membrane | Small membrane protein detected experimentally. Found to co-fractionate with the inner membrane. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.099 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-29o | CytoplasmicMembrane | 9 | ||||||
| YNEM_ECOLI | A5A616 | yneM | b4599 JW1527.1 | integral IM protein (SEC in IM), Small MgtS | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Experimentally verified orientation: N(out)-C(in). | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.123 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-25o | CytoplasmicMembrane | 9 | ||||||
| YDGU_ECOLI | A5A617 | ydgU | b4601 JW1589 | integral IM protein (SEC in IM), YdgU | Integral Inner Membrane | Small membrane protein detected experimentally. | PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | - | SRP | SEC | no | yes | N | 27 | 0.097 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-26o | Unknown | 2 | |||||||
| YNHF_ECOLI | A5A618 | ynhF | b4602 JW1649.1 | integral IM protein (SEC in IM), YnhF | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Can be inserted in both orientations (Cout-Nin and Cin-Nout). | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out, out/in | IM (predicted) | Cell inner membrane | - | SRP | SEC | no | yes | N | 27 | 0.105 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-28o | CytoplasmicMembrane | 9 | ||||||
| DINQ_ECOLI | A5A624 | dinQ | b4613 | integral IM protein (SEC in IM), DinQ | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | - | SRP | SEC | no | yes | N | 31 | 0.097 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i20-38o | Unknown | 2 | |||||||||
| TISB_ECOLI | A5A627 | tisB ysdB | ysdB | b4618 JW3649 | integral IM protein (SEC in IM), Small toxin TisB | Integral Inner Membrane | Potentially toxic protein. | PMID: 18761622 PMID: 19121005 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | - | SRP | SEC | pseudogene (Uniprot), pseudogene (Ecogene) | no | no | N | 23 | 0.099 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-25i | Unknown | 2 | ||||
| YTCA_ECOLI | A5A630 | ytcA | b4622 | integral IM protein (SEC in IM), YtcA | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SEC | no | yes | N | 33 | 0.139 | TMH | 0 | 10.1309 | - | 2 | 2 | Y | n16-27c32/33o42-61i68-90o | CytoplasmicMembrane | 10 | ||||||||||
| YTHA_ECOLI | A8DYQ1 | ythA | b4655 JW5769.1 | integral IM protein (SEC in IM), YthA | Integral Inner Membrane | Small membrane protein detected experimentally | PMID: 19121005 | Integral Inner Membrane | B | Bin | in/out | N/A | Cell inner membrane | - | SEC | no | yes | N | 41 | 0.12 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i21-40o | CytoplasmicMembrane | 9 | |||||||
| YKGR_ECOLI | C1P5Z8 | ykgR | b4671 JW5035.1 | integral IM protein (SEC in IM), YkgR | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Experimentally verified orientation: N(in)-C(out). | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | - | SRP | SEC | no | yes | N | 21 | 0.096 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i12-30o | Unknown | 2 | ||||||
| YMIB_ECOLI | C1P5Z9 | ymiB | b4672 JW1278.1 | integral IM protein (SEC in IM), Putative YmiB | Integral Inner Membrane | B | Binout | in/out | N/A | Membrane | - | SRP | SEC | no | yes | N | 28 | 0.1 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i12-29o | Unknown | 2 | |||||||||
| YOAK_ECOLI | C1P602 | yoaK | b4676 JW5292.1 | integral IM protein (SEC-YidC in IM), YoaK | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Can be inserted in both orientations (Cout-Nin and Cin-Nout). Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreased. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out, out/in | N/A | Cell inner membrane | - | SRP | SEC-YidC | no | yes | N | 29 | 0.152 | TMH | 0 | 3.55641 | - | 1 | 1 | N | o6-29i | CytoplasmicMembrane | 9 | ||||||
| YOAJ_ECOLI | C1P603 | yoaJ | b4675 JW5292.2 | integral IM protein (SEC-YidC in IM), YoaJ | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Experimentally verified orientation: N(in)-C(out). Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreased. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | - | SRP | SEC-YidC | no | yes | N | 19 | 0.098 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-23i | CytoplasmicMembrane | 9 | ||||||
| YOHP_ECOLI | C1P609 | yohP | b4679 JW5358.1 | integral IM protein (SEC in IM), YohP | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Can be inserted in both orientations (Cout-Nin and Cin-Nout). | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out, out/in | N/A | Cell inner membrane | - | SRP | SEC | no | yes | N | 25 | 0.1 | TMH | 0 | 0.568556 | - | 1 | 1 | N | o6-26i | CytoplasmicMembrane | 9 | ||||||
| YPDK_ECOLI | C1P610 | ypdK | b4680 JW2375.1 | integral IM protein (SEC in IM), YpdK | Integral Inner Membrane | Found to co-fractionate with the inner membrane. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | out/in | N/A | Cell inner membrane | - | SRP | SEC | no | yes | N | 17 | 0.106 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-22i | CytoplasmicMembrane | 9 | ||||||
| SHOB_ECOLI | C1P611 | shoB ryfB yphI | ryfB yphI | b4687 JW2546.1 | integral IM protein (SEC in IM), Small toxin ShoB | Integral Inner Membrane | PMID: 18710431 PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | N/A | Membrane | - | SRP | SEC | no | yes | N | 13 | 0.098 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-25o | CytoplasmicMembrane | 9 | ||||||
| YQFG_ECOLI | C1P614 | yqfG | b4684 JW5470.1 | integral IM protein (SEC in IM), YqfG | Integral Inner Membrane | Small protein detected experimentally. | PMID: 19121005 | Integral Inner Membrane | B | - | N/A | - | SRP | SEC | no | yes | N | 24 | 0.133 | TMH | 0 | 2.01664 | - | 1 | 0 | Y | n7-17c29/30o | CytoplasmicMembrane | 9 | ||||||||
| IBSD_ECOLI | C1P616 | ibsD | b4664 JW3023.1 | integral IM protein (SEC in IM), Small toxin IbsD | Integral Inner Membrane | Belongs to the toxic protein ibs family. Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | - | N/A | Membrane | - | SEC | no | yes | N | 18 | 0.098 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n4-9c13/14o | CytoplasmicMembrane | 9 | ||||||||
| PMRR_ECOLI | G3MTW7 | pmrR | b4703 JW4072.1 | integral IM protein (SEC in IM), Putative PmrR | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | - | SEC | no | N | 0.098 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i9-26o | Unknown | 2 | ||||||||||||
| PHSM_ECOLI | P00490 | malP | b3417 JW5689 | integral IM protein (SEC in IM), Maltodextrin phosphorylase MalP | Integral Inner Membrane | PMID: 15919657 | Integral Inner Membrane | B | - | Soluble IM Fraction | Cytoplasmic | SEC | yes | yes | N | 54 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| PTM3C_ECOLI | P00550 | mtlA | b3599 JW3573 | integral IM protein (SEC in IM), PTS system mannitol-specific EIICBA component MtlA | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. The signal anchor sequence of MtlA confers novel properties onto nascent chains of OmpA of being co-translationally recognized and targeted to SecY by SRP. PMCID: PMC305875 The signal anchor sequence of MtlA confers novel properties onto nascent chains of OmpA of being co-translationally recognized and targeted to SecY by SRP. Once targeted to SecY, ribosome-associated nascent chains of the hybrid protein, however, remain untranslocated unless SecA is present. These results indicate that SRP and SecA cooperate in a sequential, non-overlapping manner. PMCID: PMC305875 | PMID: 15919657 PMID: 15919996 PMID: 9008159 PMID: 9260961 PMCID: PMC305875 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 23 | 0.115 | TMH | 0 | 11.9934 | - | 8 | 8 | N | i20-42o48-66i78-98o133-154i161-181o213-234i269-292o312-334i | CytoplasmicMembrane | 10 | 26 | |||||
| LEP_ECOLI | P00803 | lepB | b2568 JW2552 | integral IM protein (SEC-YidC in IM), Signal peptidase I LepB | Integral Inner Membrane | Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreased. Lep was shown to be targeted to the membrane by the SRP pathway. PMID: 8985168 Disulfide bridge (171 177) | PMID: 15919996 PMID: 21778229 PMID: 2551889 PMID: 8985168 | Integral Inner Membrane | B | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SEC-YidC | yes | yes | N | 22 | 0.131 | SpII | 20 | 3.04951 | Pos+2=V | 2 | 0 | Y | n5-16c21/22o | CytoplasmicMembrane | 10 | 27 | |||||||
| LSPA_ECOLI | P00804 | lspA lsp | lsp | b0027 JW0025 | integral IM protein (SEC in IM), Signal peptidase II LspA | Integral Inner Membrane | Catalyzes the removal of signal peptides from prolipoproteins. | PMID: 15919996 PMID: 6368552 PMID: 6378662 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.135 | TMH | 0 | 7.83163 | - | 4 | 4 | N | i12-31o70-88i100-117o137-157i | CytoplasmicMembrane | 10 | 5 | ||||
| MALF_ECOLI | P02916 | malF | b4033 JW3993 | integral IM protein (SEC in IM), Maltose/maltodextrin transport system permease MalF | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. MalF functions in maltose transport as a 1:1:2 complex with the integral inner membrane protein MalG and the peripheral inner membrane protein MalK. Crystal structure of a catalytic intermediate of the maltose transporter. PMID: 18033289 Potential substrate of periplasmic chaperone YfgM). PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 15919996 PMID: 18033289 PMID: 18456666 PMID: 25403562 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | YfgM | no | yes | N | 65 | 0.175 | TMH | 0 | 14.2023 | - | 8 | 8 | N | i14-34o40-58i67-91o277-303i315-340o371-392i426-447o484-506i | CytoplasmicMembrane | 10 | |||||
| PBPA_ECOLI | P02918 | mrcA ponA | ponA | b3396 JW3359 | integral IM protein (SEC in IM), Penicillin-binding 1A MrcA | Integral Inner Membrane | The formation of a complex between a murein polymerase (PBP1B) and a murein hydrolase (MltA) in the presence of MipA represents a first step in a reconstitution of the hypothetical murein-synthesizing holoenzyme, postulated to be responsible for controlled growth of the stress-bearing sacculus of E. coli. The two OM lipoproteins, LpoA and LpoB, are essential for the function, respectively, of PBP1A and PBP1B, the major E. coli bifunctional peptidoglycans (PG) synthases. Each Lpo protein binds specifically to its cognate PBP and stimulates its transpeptidase activity, thereby facilitating attachment of new peptidoglycans to the PG sacculus. Uniprot annotation is Cell inner membrane; Single-pass type II membrane protein, Gene Ontology and Echolocation annotation is Membrane anchored. PMID: 3510188 | PMID: 10037771 PMID: 15919657 PMID: 21183073 PMID: 3510188 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 25 | 0.144 | TMH | 0 | 2.26474 | - | 1 | 0 | Y | n7-17c24/25o | CytoplasmicMembrane | 10 | 4 | ||||
| PBPB_ECOLI | P02919 | mrcB pbpF ponB | pbpF ponB | b0149 JW0145 | integral IM protein (SEC in IM), Penicillin-binding 1B MrcB | Integral Inner Membrane | The two OM lipoproteins, LpoA and LpoB, are essential for the function, respectively, of PBP1A and PBP1B, the major E. coli bifunctional peptidoglycans (PG) synthases. Each Lpo protein binds specifically to its cognate PBP and stimulates its transpeptidase activity, thereby facilitating attachment of new peptidoglycans to the PG sacculus. Cell inner membrane; Single-pass type II membrane protein. Monoisotopic peripheral; Contains amphipathic a-helix. | PMID: 15919657 PMID: 19458048 PMID: 21183073 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Single-pass type II membrane protein | Membrane anchored | SRP | SEC | yes | yes | N | 3 | 0.105 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i65-86o | CytoplasmicMembrane | 10 | |||||
| LACY_ECOLI | P02920 | lacY | b0343 JW0334 | integral IM protein (SEC in IM), Lactose permease LacY | Integral Inner Membrane | Crystal structure of lactose permease indicated that the molecule is composed of N- and C-terminal domains, each with six transmembrane helices, symmetrically positioned within the permease PMID: 12893935. | PMID: 11266632 PMID: 12893935 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.125 | TMH | 0 | 18.848 | - | 11 | 12 | N | i12-34o46-66i75-95o101-122i143-162o168-187i222-239o259-279i291-310o316-337i349-369o381-401i | CytoplasmicMembrane | 10 | ||||||
| MELB_ECOLI | P02921 | melB mel-4 | mel-4 | b4120 JW4081 | integral IM protein (SEC in IM), Melibiose carrier MelB | Integral Inner Membrane | PMID: 15919996 PMID: 7703254 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 18 | 0.118 | TMH | 0 | 8.17946 | - | 12 | 12 | N | i12-31o37-57i78-100o106-130i150-171o177-198i236-258o270-290i297-318o324-353i374-397o409-432i | CytoplasmicMembrane | 10 | ||||||
| TONB_ECOLI | P02929 | tonB exbA | exbA | b1252 JW5195 | integral IM protein (SEC in IM), TonB | Integral Inner Membrane | PMID: 11967085 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane; Single-pass membrane protein; Periplasmic side | Membrane anchored | SEC | yes | yes | N | 43 | 0.176 | TMH | 0 | 3.06055 | - | 0 | 1 | N | i12-32o | Unknown | 2 | |||||||
| MCP1_ECOLI | P02942 | tsr cheD | cheD | b4355 JW4318 | integral IM protein (SEC in IM), Methyl-accepting chemotaxis I Tsr | Integral Inner Membrane | PMID: 15919996 PMID: 22380631 | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.141 | SpI | 25 | 5.90497 | - | 2 | 1 | Y | n10-21c26/27o192-214i | CytoplasmicMembrane | 10 | 44 | |||||
| KEFC_ECOLI | P03819 | kefC trkC | trkC | b0047 JW0046 | integral IM protein (SEC in IM), Glutathione-regulated potassium-efflux system KefC | Integral Inner Membrane | PMID: 15919996 PMID: 2046548 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.112 | TMH | 0 | 7.67646 | - | 13 | 13 | N | o6-24i31-49o55-72i84-111o117-135i147-169o181-202i214-233o239-258i270-290o296-315i327-348o360-378i | CytoplasmicMembrane | 10 | ||||||
| GSPB_ECOLI | P03825 | gspB pinO pioO pno | pinO pioO pno | b3322 JW3284 | integral IM protein (SEC in IM), Putative general secretion pathway B GspB | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 43 | 0.123 | TMH | 0 | 3.27755 | - | 1 | 1 | N | o28-51i | Unknown | 2 | ||||||||
| KDPA_ECOLI | P03959 | kdpA | b0698 JW0686 | integral IM protein (SEC in IM), Potassium-transporting ATPase potassium-binding subunit KdpA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.183 | TMH | 0 | 0.239367 | - | 12 | 12 | Y | n5-16c20/21o59-82i94-115o135-155i167-190o253-271i283-301o327-349i356-374o380-398i418-437o484-505i526-548o | CytoplasmicMembrane | 10 | 10 | ||||||
| KDPB_ECOLI | P03960 | kdpB | b0697 JW0685 | integral IM protein (SEC in IM), Potassium-transporting ATPase ATP-binding subunit KdpB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 55 | 0.195 | CYT | 0 | -0.200913 | - | 7 | 6 | N | i35-56o62-82i219-240o252-274i616-636o656-681i | CytoplasmicMembrane | 10 | 8 | ||||||
| KDPC_ECOLI | P03961 | kdpC | b0696 JW0684 | integral IM protein (SEC in IM), Potassium-transporting ATPase KdpC subunit KdpC | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 39 | 0.2 | TMH | 0 | 11.3621 | - | 1 | 0 | Y | n7-18c30/31o | CytoplasmicMembrane | 10 | 18 | ||||||||
| MCP3_ECOLI | P05704 | trg | b1421 JW1417 | integral IM protein (SEC in IM), Methyl-accepting chemotaxis III Trg | Integral Inner Membrane | PMID: 15919996 PMID: 22380631 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 40 | 0.259 | TMH | 0 | 7.8524 | - | 2 | 2 | N | i20-44o199-222i | CytoplasmicMembrane | 10 | 34 | ||||||
| FTSQ_ECOLI | P06136 | ftsQ | b0093 JW0091 | integral IM protein (SEC in IM), Cell division FtsQ | Integral Inner Membrane | FtsQ could be localized to the division site in constricting cells. FtsQ insertion requires SecYEG, the transmembrane electrical potential, SecA, and the SRP pathway. PMID: 15546656 YidC plays a role in the membrane integration of the FtsQ protein as the hydrophobic region of FtsQ can be cross-linked to YidC. PMID: 15546656 | PMID: 11415986 PMID: 11703663 PMID: 11948172 PMID: 15165235 PMID: 15546656 PMID: 17693520 PMID: 2007547 PMID: 9829918 PMID: 9882666 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 41 | 0.115 | TMH | 0 | 1.18618 | - | 1 | 1 | N | i25-49o | Unknown | 2 | 24 | |||||
| BTUC_ECOLI | P06609 | btuC | b1711 JW1701 | integral IM protein (SEC-YidC in IM), Vitamin B12 import system permease BtuC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 11266632 PMID: 12004122 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 34 | 0.278 | TMH | 0 | 13.5896 | - | 9 | 9 | Y | n16-29c34/35o58-77i89-109o115-133i145-168o188-206i213-232o238-262i274-297o303-322i | CytoplasmicMembrane | 10 | ||||||
| BIRA_ECOLI | P06709 | birA bioR dhbB | bioR dhbB | b3973 JW3941 | nucleoid & integral IM protein (SEC in IM), Bifunctional ligase/repressor BirA | Integral Inner Membrane, Nucleoid | PMID: 23138451 PMID: 23387333 | Integral Inner Membrane, Nucleoid | B, N | IM (predicted) | Cytoplasmic | SRP | SEC | yes | yes | N | 26 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 2 | N | i123-139o145-162i | Cytoplasmic | 10 | 37 | ||||||||
| FHUB_ECOLI | P06972 | fhuB | b0153 JW0149 | integral IM protein (SEC in IM), Iron(3+)-hydroxamate import system permease FhuB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.415 | TMH | 0 | 12.8147 | - | 17 | 17 | Y | n5-20c38/39o62-79i91-111o117-137i144-167o194-212i224-241o247-265i277-299o305-326i347-369o389-411i423-443o449-468i480-499o567-594i606-623o635-655i | CytoplasmicMembrane | 10 | |||||||
| PNTA_ECOLI | P07001 | pntA | b1603 JW1595 | integral IM protein (SEC in IM), PntA | Integral Inner Membrane | PMID: 14660605 PMID: 15919996 PMID: 1932078 PMID: 3525165 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 40 | 0.111 | CYT | 0 | -0.200913 | - | 5 | 4 | N | i400-418o424-443i455-472o478-499i | CytoplasmicMembrane | 10 | 110 | ||||||
| MCP2_ECOLI | P07017 | tar cheM | cheM | b1886 JW1875 | integral IM protein (SEC in IM), Methyl-accepting chemotaxis II Tar | Integral Inner Membrane | Pole-derived membrane fragments were isolated by affinity capture of vesicles containing the chemotaxis protein, Tar. PMID: 3049536 PMID: 12826616 PMID: 17144658 | PMID: 12826616 PMID: 15919996 PMID: 17144658 PMID: 22380631 PMID: 3049536 | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 20 | 0.158 | TMH | 0 | 4.99054 | - | 2 | 1 | Y | n10-21c26/27o192-212i | CytoplasmicMembrane | 10 | 73 | ||||
| MCP4_ECOLI | P07018 | tap | b1885 JW1874 | integral IM protein (SEC in IM), Methyl-accepting chemotaxis IV Tap | Integral Inner Membrane | PMID: 15919996 PMID: 22380631 | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 35 | 0.179 | TMH | 0 | 6.20402 | - | 2 | 1 | Y | n10-21c34/35o187-209i | CytoplasmicMembrane | 10 | 5 | ||||||
| PUTP_ECOLI | P07117 | putP | b1015 JW1001 | integral IM protein (SEC in IM), Sodium/proline symporter PutP | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 PMID: 3302614 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 28 | 0.128 | TMH | 0 | 13.7134 | - | 12 | 12 | N | i7-26o66-88i127-152o164-186i193-213o233-256i277-296o325-350i371-391o403-422i429-449o455-473i | CytoplasmicMembrane | 10 | |||||||
| PSTA_ECOLI | P07654 | pstA phoT | phoT | b3726 JW3704 | integral IM protein (SEC in IM), Phosphate transport system permease PstA | Integral Inner Membrane | PMID: 15919996 PMID: 3881386 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 14 | 0.135 | TMH | 0 | 14.9057 | - | 6 | 6 | N | i29-50o89-111i123-145o151-169i201-222o267-290i | CytoplasmicMembrane | 10 | ||||||
| GLPT_ECOLI | P08194 | glpT | b2240 JW2234 | integral IM protein (SEC in IM), Glycerol-3-phosphate transporter GlpT | Integral Inner Membrane | PMID: 11266632 PMID: 12893935 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 52 | 0.128 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i26-44o64-82i94-113o119-138i159-183o189-208i254-272o292-311i323-342o348-373i385-405o417-437i | CytoplasmicMembrane | 10 | |||||||
| CRED_ECOLI | P08369 | creD cet | cet | b4400 JW4363 | integral IM protein (SEC-YidC in IM), CreD | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 29 | 0.114 | TMH | 0 | 4.58166 | - | 6 | 5 | Y | n11-22c34/35o295-313i325-343o349-368i375-396o402-420i | CytoplasmicMembrane | 10 | 28 | ||||
| PPDB_ECOLI | P08371 | ppdB ygdC | ygdC | b2825 JW5451 | integral IM protein (SEC in IM), Prepilin peptidase-dependent B PpdB | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Membrane anchored | SRP | SEC | yes | yes | N | 36 | 0.136 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o13-34i | Unknown | 2 | 23 | ||||||||
| PPDC_ECOLI | P08372 | ppdC ygdA | ygdA | b2823 JW2791 | integral IM protein (SEC in IM), Prepilin peptidase-dependent C PpdC | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Membrane anchored | SRP | SEC | yes | yes | N | 30 | 0.122 | TMH | 0 | 6.3414 | - | 1 | 1 | N | o16-33i | Unknown | 2 | 24 | ||||||||
| SPPA_ECOLI | P08395 | sppA | b1766 JW1755 | integral IM protein (SEC in IM), Protease 4 SppA | Integral Inner Membrane | PMID: 18476724 PMID: 3522590 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 48 | 0.115 | TMH | 0 | 6.31524 | - | 1 | 1 | N | i21-43o | CytoplasmicMembrane | 10 | 14 | ||||||
| PHOR_ECOLI | P08400 | phoR nmpB | nmpB | b0400 JW0390 | integral IM protein (SEC in IM), Phosphate regulon sensor PhoR PhoR | Integral Inner Membrane | PMID: 15919996 PMID: 2187152 | Integral Inner Membrane | B | Bpoly | in/in | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 24 | 0.17 | TMH | 0 | 20.4877 | - | 1 | 2 | N | i12-36o42-59i | CytoplasmicMembrane | 10 | 13 | |||||
| CREC_ECOLI | P08401 | creC phoM | phoM | b4399 JW4362 | integral IM protein (SEC-YidC in IM), Sensor CreC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 25 | 0.159 | SpI | 27 | -0.123855 | - | 2 | 1 | Y | n7-18c24/25o184-206i | CytoplasmicMembrane | 10 | 16 | ||||
| CVPA_ECOLI | P08550 | cvpA dedE | dedE | b2313 JW2310 | integral IM protein (SEC in IM), Colicin V production CvpA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 31 | 0.117 | TMH | 0 | 6.39839 | - | 4 | 4 | N | o6-25i32-52o64-87i99-120o | CytoplasmicMembrane | 10 | ||||||
| DSDX_ECOLI | P08555 | dsdX orf445 yfdA yfdD | orf445 yfdA yfdD | b2365 JW2362 | integral IM protein (SEC in IM), D-serine transporter DsdX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 33 | 0.118 | TMH | 0 | 11.5143 | - | 12 | 12 | N | o6-23i30-47o59-77i98-128o140-158i178-198o225-244i256-282o302-322i343-365o385-408i420-444o | CytoplasmicMembrane | 10 | 12 | |||||
| PTV3B_ECOLI | P08722 | bglF bglC bglS | bglC bglS | b3722 JW3700 | integral IM protein (SEC in IM), PTS system beta-glucoside-specific EIIBCA component BglF | Integral Inner Membrane | In the absence of ??-glucosidase, associates with BglG to form a pro-form membrane complex that maintains BglG inactive. | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.16 | CYT | 0 | -0.200913 | - | 10 | 12 | N | i100-121o141-160i172-190o210-230i242-263o269-292i299-322o328-347i354-375o381-400i407-424o430-452i | CytoplasmicMembrane | 10 | |||||
| HEMX_ECOLI | P09127 | hemX | b3803 JW3775 | integral IM protein (SEC in IM), HemX | Integral Inner Membrane | PMID: 16079137 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 50 | 0.207 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i36-57o | CytoplasmicMembrane | 10 | |||||||
| PTW3C_ECOLI | P09323 | nagE pstN | pstN | b0679 JW0665 | integral IM protein (SEC in IM), PTS system N-acetylglucosamine-specific EIICBA component NagE | Integral Inner Membrane | PMID: 15919657 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 45 | 0.132 | TMH | 0 | 3.42438 | - | 10 | 12 | N | i12-32o38-61i68-88o94-112i132-153o165-185i192-212o232-252i259-276o282-306i313-331o337-359i | CytoplasmicMembrane | 10 | 1 | |||||
| MOTA_ECOLI | P09348 | motA flaJ | flaJ | b1890 JW1879 | integral IM protein (SEC in IM), Motility A MotA | Integral Inner Membrane | Interacts with flagellar brake protein YcgR in the flagellar basal bodies or FliM or FliG. | PMID: 15919996 PMID: 19364805 PMID: 20303158 PMID: 20346719 PMID: 23193105 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.167 | TMH | 0 | 4.42407 | - | 4 | 4 | Y | n2-11c16/17o32-49i70-87o171-189i201-220o | CytoplasmicMembrane | 10 | 18 | ||||
| GLPG_ECOLI | P09391 | glpG | b3424 JW5687 | integral IM protein (SEC in IM), Rhomboid protease GlpG | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 11266632 PMID: 15919996 PMID: 16216077 PMID: 17051161 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 16 | 0.202 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i96-115o135-160i172-188o194-212i224-242o248-267i | CytoplasmicMembrane | 10 | ||||||
| DEDD_ECOLI | P09549 | dedD | b2314 JW5378 | integral IM protein (SEC in IM), Cell division DedD | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 30 | 0.117 | SpI | 27 | 0.354359 | - | 1 | 1 | N | i9-27o | Unknown | 2 | |||||||||
| UHPB_ECOLI | P09835 | uhpB | b3668 JW3643 | integral IM protein (SEC in IM), Signal transduction histidine-kinase/phosphatase UhpB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.141 | TMH | 0 | 16.0266 | - | 7 | 9 | N | o6-28i40-60o80-100i112-132o138-162i183-201o207-224i231-249o255-273i | CytoplasmicMembrane | 10 | 19 | ||||||
| UHPC_ECOLI | P09836 | uhpC | b3667 JW3642 | integral IM protein (SEC in IM), sensor UhpC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 52 | 0.143 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i26-45o65-84i96-114o120-143i155-179o185-203i245-265o285-308i320-338o344-365i377-401o407-431i | CytoplasmicMembrane | 10 | |||||||
| UBIB_ECOLI | P0A6A0 | ubiB aarF yigQ yigR yigS | aarF yigQ yigR yigS | b3835 JW3812 | integral IM protein (SEC in IM), Probable kinase UbiB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 50 | 0.114 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i501-518o524-542i | CytoplasmicMembrane | 10 | 17 | |||||
| CLSA_ECOLI | P0A6H8 | clsA cls nov yciJ | cls nov yciJ | b1249 JW1241 | integral IM protein (SEC in IM), Cardiolipin synthase A ClsA | Integral Inner Membrane | In E. coli, the cls and ybhO genes (renamed clsA and clsB, respectively) each encode a CL (cardiolipin) synthase (Cls) that catalyzes the condensation of two PG molecules to form CL and glycerol. PMID: 22988102 | PMID: 15919996 PMID: 22988102 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.149 | TMH | 0 | 5.41966 | - | 2 | 2 | N | o6-25i37-58o | CytoplasmicMembrane | 10 | 3 | ||||
| CYSZ_ECOLI | P0A6J3 | cysZ | b2413 JW2406 | integral IM protein (SEC-YidC in IM), Sulfate transporter CysZ | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. PMID: 15919996 | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | yes | yes | N | 18 | 0.111 | TMH | 0 | 5.82324 | - | 4 | 5 | N | i31-51o71-92i143-163o169-188i209-242o | CytoplasmicMembrane | 10 | 19 | |||||
| DSBB_ECOLI | P0A6M2 | dsbB roxB ycgA | roxB ycgA | b1185 JW5182 | integral IM protein (SEC-YidC in IM), Disulfide bond formation B DsbB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC PMID: 22108384. The crystal structure revealed a transmembrane (TM) four-helix-bundle structure of DsbBPMID: 18406599. DsbB oxidizes the periplasmic protein DsbA, which in turn oxidizes the cysteines in other periplasmic proteins to make disulfide bondsPMID: 8430071. Gene fusion approaches were used to show that (i) DsbB is a membrane protein which spans the membrane four times and (ii) both the N- and C-termini of the protein are in the cytoplasmPMID: 7957076. The structure of DsbB revealed four transmembrane helices and one short horizontal helix juxtaposed with Cys130 in the mobile periplasmic loopPMID: 17110337. Disulfide bridge (41 44;104 130) PMID: 10064586 | PMID: 10064586 PMID: 11266632 PMID: 15919996 PMID: 17110337 PMID: 18406599 PMID: 22108384 PMID: 7957076 PMID: 8430071 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 25 | 0.286 | TMH | 0 | 4.8983 | - | 4 | 4 | N | i12-33o45-64i71-89o145-166i | CytoplasmicMembrane | 10 | 15 | ||||
| FTSB_ECOLI | P0A6S5 | ftsB ygbQ | ygbQ | b2748 JW2718 | integral IM protein (SEC in IM), Cell division FtsB | Integral Inner Membrane | PMID: 11972052 PMID: 15165235 | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 23 | 0.157 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n4-14c18/19o | CytoplasmicMembrane | 9 | 25 | |||||
| MRAY_ECOLI | P0A6W3 | mraY murX | murX | b0087 JW0085 | integral IM protein (SEC in IM), Phospho-N-acetylmuramoyl-pentapeptide-transferase MraY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.151 | CYT | 0 | -0.200913 | - | 10 | 10 | N | o20-40i73-90o96-114i134-152o172-193i200-219o239-256i263-284o290-311i338-357o | CytoplasmicMembrane | 10 | ||||||
| YCIB_ECOLI | P0A710 | yciB ispZ | ispZ | b1254 JW1246 | integral IM protein (SEC in IM), Probable intracellular septation A YciB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.173 | TMH | 0 | 7.58982 | - | 5 | 5 | N | o20-39i51-68o74-96i117-139o151-170i | CytoplasmicMembrane | 10 | ||||||
| KDGT_ECOLI | P0A712 | kdgT | b3909 JW5560 | integral IM protein (SEC in IM), 2-keto-3-deoxygluconate permease KdgT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 67 | 0.134 | TMH | 0 | 12.8678 | - | 10 | 10 | N | i12-29o35-57i78-97o103-127i139-164o170-187i194-211o223-243i255-274o286-309i | CytoplasmicMembrane | 10 | |||||||
| MSCL_ECOLI | P0A742 | mscL yhdC | yhdC | b3291 JW3252 | integral IM protein (YidC in IM), Large-conductance mechanosensitive channel MscL | Integral Inner Membrane | PMID: 15919996 PMID: 17113597 PMID: 22108384 PMID: 8890153 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | YidC | yes | yes | N | 39 | 0.143 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i21-52o72-96i | CytoplasmicMembrane | 10 | 66 | |||||
| RSXA_ECOLI | P0A766 | rsxA rnfA ydgL | rnfA ydgL | b1627 JW1619 | integral IM protein (SEC in IM), Ion-translocating oxidoreductase complex subunit A RsxA | Integral Inner Membrane | PMID: 15919996 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein(experimental) | SRP | SEC | yes | yes | N | 21 | 0.118 | TMH | 0 | 7.31415 | - | 6 | 6 | N | o6-26i38-59o65-87i99-122o134-155i167-191o | CytoplasmicMembrane | 10 | ||||||
| MNTH_ECOLI | P0A769 | mntH yfeP | yfeP | b2392 JW2388 | integral IM protein (SEC in IM), Divalent metal cation transporter MntH | Integral Inner Membrane | PMID: 14607838 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 28 | 0.129 | TMH | 0 | 9.54648 | - | 11 | 11 | N | i21-40o52-75i95-116o122-144i156-176o196-216i237-263o283-313i325-343o349-370i391-410o | CytoplasmicMembrane | 10 | ||||||
| GPMB_ECOLI | P0A7A2 | gpmB ytjC | ytjC | b4395 JW4358 | integral IM protein (SEC in IM), Probable phosphoglycerate mutase GpmB | Large potential TM 146-168aa | Integral Inner Membrane | B | Binout | out/in | N/A | Membrane anchored | SRP | SEC | no | yes | N | 17 | 0.117 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o146-168i | Cytoplasmic | 9 | 56 | |||||||
| PSIE_ECOLI | P0A7C8 | psiE yjbA | yjbA | b4030 JW3990 | integral IM protein (SEC in IM), PsiE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 43 | 0.143 | TMH | 0 | 4.00332 | - | 4 | 4 | N | i12-35o55-74i86-105o111-128i | CytoplasmicMembrane | 10 | ||||||
| DCTA_ECOLI | P0A830 | dctA | b3528 JW3496 | integral IM protein (SEC-YidC in IM), Aerobic C4-dicarboxylate transport protein DctA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 19 | 0.136 | TMH | 0 | 5.74612 | - | 8 | 8 | N | i9-27o47-64i76-99o141-164i184-208o220-242i326-344o350-373i | CytoplasmicMembrane | 10 | ||||||
| TATE_ECOLI | P0A843 | tatE ybeC | ybeC | b0627 JW0622 | integral IM protein (SEC in IM), Sec-independent translocase TatE | Integral Inner Membrane | TatA paralog TatE can substitute for TatA and support translocation of Tat substrates including AmiA, AmiC, and TorA. | PMID: 22190680 | Integral Inner Membrane | B | Bout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 43 | 0.118 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n9-20c29/30o | CytoplasmicMembrane | 9 | 127 | ||||
| YFBV_ECOLI | P0A8D9 | yfbV | b2295 JW2292 | integral IM protein (SEC in IM), UPF0208 YfbV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.122 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i46-64o70-90i | CytoplasmicMembrane | 10 | 38 | ||||||
| ZUPT_ECOLI | P0A8H3 | zupT ygiE | ygiE | b3040 JW3008 | integral IM protein (SEC in IM), Zinc transporter ZupT | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 59 | 0.198 | TMH | 0 | 10.378 | - | 6 | 7 | N | o6-25i32-50o62-81i125-150o170-192i199-215o235-256i | CytoplasmicMembrane | 10 | 27 | |||||||
| YIHY_ECOLI | P0A8K8 | yihY | b3886 JW3857 b2268 | integral IM protein (SEC in IM), UPF0761 YihY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 60 | 0.127 | CYT | 0 | -0.200913 | - | 6 | 7 | N | o39-61i73-91o103-120i141-160o180-200i212-234o240-266i | CytoplasmicMembrane | 10 | |||||||
| FRDC_ECOLI | P0A8Q0 | frdC | b4152 JW4113 | integral IM protein (SEC in IM), Fumarate reductase subunit C FrdC | Integral Inner Membrane | Alpha-helcal transmembrane protein (experimental). Transmembrane helices: 3. N-terminal region is in cytoplasm. Helix A and B connected by very short turns to an interfacial helix (N51-L63)PMID: 24057063. | PMID: 10373108 PMID: 11266632 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 59 | 0.224 | TMH | 0 | 1.78374 | - | 3 | 3 | N | i26-48o68-88i109-130o | CytoplasmicMembrane | 10 | 9 | |||||
| FRDD_ECOLI | P0A8Q3 | frdD | b4151 JW4112 | integral IM protein (SEC in IM), Fumarate reductase subunit D FrdD | Integral Inner Membrane | Alpha-helcal transmembrane protein (experimental). Transmembrane helices: 3 PMID: 10373108. | PMID: 10373108 PMID: 11266632 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 52 | 0.162 | TMH | 0 | 15.5267 | - | 3 | 3 | N | i12-45o57-78i99-118o | CytoplasmicMembrane | 10 | 7 | |||||
| YCJF_ECOLI | P0A8R7 | ycjF | b1322 JW1315 | integral IM protein (SEC in IM), UPF0283 YcjF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.1 | CYT | 0 | -0.200913 | - | 3 | 4 | N | i70-87o99-120i214-236o256-275i | CytoplasmicMembrane | 10 | 10 | ||||||
| USPB_ECOLI | P0A8S5 | uspB yhiO | yhiO | b3494 JW3461 | integral IM protein (SEC in IM), Universal stress B UspB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.13 | TMH | 0 | 0.843073 | - | 2 | 2 | N | o6-24i90-110o | CytoplasmicMembrane | 10 | 57 | |||||
| PGPB_ECOLI | P0A924 | pgpB | b1278 JW1270 | integral IM protein (SEC in IM), Phosphatidylglycerophosphatase B PgpB | Integral Inner Membrane | PgpB protein has phosphatidyl glycerophosphate phosphatase activity higher in the cytoplasmic membrane, while it has phosphatidic acid and lysophosphatidic acid phosphatase activities higher in the outer membrane. | PMID: 15919996 PMID: 2846511 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.144 | TMH | 0 | 17.4928 | - | 6 | 6 | N | i12-29o49-68i75-96o157-178i185-206o212-230i | CytoplasmicMembrane | 10 | ||||||
| ESSD_ECOLI | P0A9R2 | essD ybcR | ybcR | b0554 JW0543 | integral IM protein (SEC in IM), Prophage lysis S homolog EssD | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | yes | no | N | 38 | 0.193 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i7-25o37-58i | Unknown | 2 | 14 | |||||||
| PLAP_ECOLI | P0AA47 | plaP yeeF | yeeF | b2014 JW5330 | integral IM protein (SEC in IM), Low-affinity putrescine importer PlaP | Integral Inner Membrane | Old gene name YeeF. | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.148 | TMH | 0 | 8.96423 | - | 12 | 12 | N | i20-42o54-73i94-116o128-146i158-179o199-217i237-260o287-315i336-355o361-383i395-413o419-437i | CytoplasmicMembrane | 10 | |||||
| YFDV_ECOLI | P0AA49 | yfdV | b2372 JW2369 | integral IM protein (SEC in IM), transporter YfdV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 57 | 0.126 | CYT | 0 | -0.200913 | - | 10 | 10 | N | o6-23i35-55o67-90i97-117o129-150i175-196o202-222i234-253o259-278i290-309o | CytoplasmicMembrane | 10 | |||||||
| QMCA_ECOLI | P0AA53 | qmcA ybbK | ybbK | b0489 JW0478 | integral IM protein (SEC in IM), QmcA | Integral Inner Membrane | PMID: 16573693 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 18 | 0.11 | TMH | 0 | 1.35378 | - | 1 | 0 | Y | n2-13c18/19o | Unknown | 2 | 13 | |||||
| YGHB_ECOLI | P0AA60 | yghB | b3009 JW2976 | integral IM protein (SEC in IM) of DedA family, YghB | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.338 | TMH | 0 | 0.0786812 | - | 4 | 6 | N | o20-38i45-62o68-88i123-143o155-176i188-212o | CytoplasmicMembrane | 10 | 8 | |||||
| YQJA_ECOLI | P0AA63 | yqjA | b3095 JW3066 | integral IM protein (SEC in IM) of DedA family, YqjA | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.127 | TMH | 0 | 4.47784 | - | 6 | 6 | N | o20-38i45-62o68-88i123-143o155-176i188-212o | CytoplasmicMembrane | 10 | 3 | |||||
| RHTA_ECOLI | P0AA67 | rhtA ybiF | ybiF | b0813 JW0798 | integral IM protein (SEC in IM), Threonine/homoserine exporter RhtA | Integral Inner Membrane | PMID: 12648727 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.17 | TMH | 0 | 6.46418 | - | 10 | 9 | Y | n10-18c22/23o38-59i71-89o95-115i122-139o145-165i177-196o202-225i237-258o264-283i | CytoplasmicMembrane | 10 | ||||||
| YEDA_ECOLI | P0AA70 | yedA | b1959 JW1942 | integral IM protein (SEC in IM), transporter YedA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.125 | TMH | 0 | 11.0617 | - | 10 | 9 | Y | n6-16c21/22o37-56i68-86o98-117i124-143o149-169i176-199o211-233i245-262o268-290i | CytoplasmicMembrane | 10 | |||||||
| YHBE_ECOLI | P0AA73 | yhbE | b3184 JW3151 | integral IM protein (SEC in IM), transporter YhbE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.149 | TMH | 0 | 0.144382 | - | 10 | 10 | N | i7-26o38-56i71-91o103-120i132-151o157-177i189-205o217-236i248-269o281-299i | CytoplasmicMembrane | 10 | |||||||
| DGOT_ECOLI | P0AA76 | dgoT yidT | yidT | b3691 JW5859 | integral IM protein (SEC-YidC in IM), D-galactonate transporter DgoT | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 43 | 0.138 | TMH | 0 | 4.18214 | - | 11 | 12 | N | i15-35o55-75i82-98o104-122i142-163o169-188i242-263o283-304i316-332o338-362i369-392o404-424i | CytoplasmicMembrane | 10 | |||||
| EXUT_ECOLI | P0AA78 | exuT | b3093 JW3064 | integral IM protein (SEC in IM), Hexuronate transporter ExuT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 18 | 0.107 | TMH | 0 | 0.456812 | - | 11 | 12 | N | i47-66o86-109i116-136o142-162i174-199o205-224i277-299o305-325i345-362o368-389i401-424o430-452i | CytoplasmicMembrane | 10 | |||||||
| GARP_ECOLI | P0AA80 | garP yhaU | yhaU | b3127 JW3096 | integral IM protein (SEC in IM), Probable galactarate transporter GarP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.195 | TMH | 0 | 3.99251 | - | 11 | 12 | N | i12-32o52-73i85-103o109-130i151-173o179-199i251-270o290-314i326-345o351-372i379-406o412-434i | CytoplasmicMembrane | 10 | ||||||
| CODB_ECOLI | P0AA82 | codB | b0336 JW0327 | integral IM protein (SEC-YidC in IM), Cytosine permease CodB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 38 | 0.154 | TMH | 0 | 12.7134 | - | 12 | 12 | N | i20-40o52-74i95-118o130-147i152-173o193-212i224-253o259-278i299-318o324-345i357-379o385-402i | CytoplasmicMembrane | 10 | ||||||
| DSBE_ECOLI | P0AA86 | dsbE ccmG yejQ | ccmG yejQ | b2195 JW2183 | integral IM protein (SEC in IM), Thiol:disulfide interchange DsbE | Integral Inner Membrane | PMID: 16364305 PMID: 9537397 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane; Single-pass membrane protein; Periplasmic side | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 29 | 0.264 | SpI | 27 | 8.59712 | - | 1 | 0 | Y | n6-21c30/31o | CytoplasmicMembrane | 10 | 69 | |||||
| YPDA_ECOLI | P0AA93 | ypdA | b2380 JW5388 | integral IM protein (SEC in IM), Sensor histidine kinase YpdA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 16 | 0.103 | TMH | 0 | 1.16348 | - | 6 | 6 | N | o6-25i45-64o76-99i106-128o140-161i173-191o | CytoplasmicMembrane | 10 | |||||||
| YAGU_ECOLI | P0AAA1 | yagU | b0287 JW0281 | integral IM protein (SEC in IM), YagU | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.316 | SpI | 29 | 3.31288 | - | 3 | 4 | N | i14-35o98-120i132-150o162-182i | CytoplasmicMembrane | 10 | 44 | ||||||
| YMCE_ECOLI | P0AAA5 | ymcE sfa | sfa | b0991 JW0975 | integral IM protein (SEC in IM), YmcE | Integral Inner Membrane | B | Bout | in/out | N/A | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 46 | 0.141 | TMH | 0 | 4.44945 | - | 1 | 0 | Y | n15-25c29/30o | Unknown | 2 | 100 | |||||||
| WZXE_ECOLI | P0AAA7 | wzxE wzx yifJ | wzx yifJ | b3792 JW3766 | integral IM protein (SEC in IM), Lipid III flippase WzxE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.139 | TMH | 0 | 5.34268 | - | 12 | 11 | Y | n6-16c21/22o45-67i79-105o117-138i145-164o176-195i216-237o257-278i299-322o334-355i362-382o394-412i | CytoplasmicMembrane | 10 | ||||||
| YBHL_ECOLI | P0AAC4 | ybhL | b0786 JW0769 | integral IM protein (SEC in IM), YbhL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.151 | TMH | 0 | 5.60898 | - | 7 | 7 | N | i20-42o57-77i89-107o113-131i143-161o167-186i207-230o | CytoplasmicMembrane | 10 | |||||||
| YCCA_ECOLI | P0AAC6 | yccA | b0970 JW0953 | integral IM protein (SEC in IM), Modulator of FtsH protease YccA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.268 | TMH | 0 | 7.78202 | - | 7 | 7 | N | i20-41o47-67i74-94o106-126i133-154o160-184i196-216o | CytoplasmicMembrane | 10 | |||||||
| MTR_ECOLI | P0AAD2 | mtr | b3161 JW3130 | integral IM protein (SEC in IM), Tryptophan-specific transport Mtr | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 47 | 0.192 | TMH | 0 | 19.2156 | - | 11 | 11 | N | i12-34o40-65i86-107o127-145i152-170o190-207i228-246o284-309i321-340o346-367i388-410o | CytoplasmicMembrane | 10 | |||||||
| TYRP_ECOLI | P0AAD4 | tyrP | b1907 JW1895 | integral IM protein (SEC in IM), Tyrosine-specific transport TyrP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 29 | 0.164 | TMH | 0 | 11.6392 | - | 11 | 10 | Y | n6-17c29/30o39-58i78-100o120-141i148-169o181-204i216-235o273-298i310-330o336-355i376-399o | CytoplasmicMembrane | 10 | |||||||
| SDAC_ECOLI | P0AAD6 | sdaC dcrA | dcrA | b2796 JW2767 | integral IM protein (SEC in IM), Serine transporter SdaC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 36 | 0.132 | TMH | 0 | 10.9503 | - | 11 | 11 | N | i24-43o49-67i100-120o140-157i164-187o207-229i250-273o300-324i345-364o370-394i406-428o | CytoplasmicMembrane | 10 | ||||||
| TDCC_ECOLI | P0AAD8 | tdcC | b3116 JW3087 | integral IM protein (SEC in IM), Threonine/serine transporter TdcC | Integral Inner Membrane | Potential substrate of periplasmic chaperone YfgM). PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 15919996 PMID: 25403562 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | YfgM | yes | yes | N | 35 | 0.131 | TMH | 0 | 9.58087 | - | 11 | 11 | N | i23-42o48-66i97-116o136-155i167-186o206-234i255-278o317-337i358-379o391-409i421-440o | CytoplasmicMembrane | 10 | |||||
| CYCA_ECOLI | P0AAE0 | cycA dagA ytfD | dagA ytfD | b4208 JW4166 | integral IM protein (SEC-YidC in IM), D-serine/D-alanine/glycine transporter CycA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 53 | 0.108 | TMH | 0 | 3.35425 | - | 12 | 12 | N | i28-45o51-71i108-130o136-154i166-187o207-231i252-274o286-311i347-365o371-397i417-435o441-460i | CytoplasmicMembrane | 10 | |||||
| PROY_ECOLI | P0AAE2 | proY yajM | yajM | b0402 JW5055 | integral IM protein (SEC in IM), Proline-specific permease ProY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.136 | TMH | 0 | 6.32309 | - | 12 | 12 | N | i16-34o40-59i95-118o124-142i154-176o196-218i239-258o278-298i330-350o356-377i398-421o427-445i | CytoplasmicMembrane | 10 | ||||||
| ARCD_ECOLI | P0AAE5 | ydgI | b1605 JW1597 | nucleoid & integral IM protein (SEC in IM), Putative arginine/ornithine antiporter YdgI | Integral Inner Membrane, Nucleoid | PMID: 15919996 PMID: 23138451 | Integral Inner Membrane, Nucleoid | B, N | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.206 | TMH | 0 | 8.33129 | - | 13 | 12 | Y | n5-16c25/26o41-61i82-107o127-145i157-178o204-222i234-257o283-311i332-352o358-378i385-402o408-426i441-459o | CytoplasmicMembrane | 10 | ||||||||
| CADB_ECOLI | P0AAE8 | cadB | b4132 JW4093 | integral IM protein (SEC-YidC in IM), Probable cadaverine/lysine antiporter CadB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 18 | 0.152 | TMH | 0 | 9.00829 | - | 12 | 12 | N | i7-28o40-58i94-115o121-139i146-169o189-208i220-238o258-283i323-344o350-371i383-401o407-424i | CytoplasmicMembrane | 10 | ||||||
| POTE_ECOLI | P0AAF1 | potE | b0692 JW0679 | integral IM protein (SEC in IM), Putrescine transporter PotE PotE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 50 | 0.144 | TMH | 0 | 5.94665 | - | 12 | 12 | N | i12-30o42-60i90-110o122-140i152-172o184-204i225-249o276-300i321-345o351-374i386-404o410-428i | CytoplasmicMembrane | 10 | |||||||
| MDLB_ECOLI | P0AAG5 | mdlB mdl | mdl | b0449 JW5061 | integral IM protein (SEC in IM), Multidrug resistance-like ATP-binding MdlB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.136 | SpI | 37 | 4.21577 | - | 4 | 4 | Y | n25-32c37/38o61-81i138-161o167-185i250-273o | CytoplasmicMembrane | 10 | 6 | |||||
| FTSH_ECOLI | P0AAI3 | ftsH hflB mrsC std tolZ | hflB mrsC std tolZ | b3178 JW3145 | integral IM protein (SEC in IM), ATP-dependent zinc metalloprotease FtsH | Integral Inner Membrane | Trigger factor-sensitive aggregation. PMID: 8444797 PMID: 1925026 PMID: 8106505 PMID: 8106505 PMID: 7781608 | PMID: 15919657 PMID: 15919996 PMID: 1925026 PMID: 19737520 PMID: 7500942 PMID: 7781608 PMID: 8106505 PMID: 8444797 PMID: 8947034 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP,TF | SEC | no | yes | N | 24 | 0.152 | SpI | 21 | 2.2847 | - | 2 | 1 | Y | n5-16c21/22o98-119i | CytoplasmicMembrane | 10 | 41 | ||||
| FDNH_ECOLI | P0AAJ3 | fdnH | b1475 JW1471 | integral IM protein (SEC in IM), Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit FdnH | Integral Inner Membrane | Part of the formate dehydrogenase N (FDH-N) of Escherichia coli which is a membrane-bound enzyme comprising FdnG, FdnH, and FdnI subunits. PMID: 11884747 PMID: 16858726 | PMID: 11266632 PMID: 11884747 PMID: 15342602 PMID: 16858726 | Integral Inner Membrane | B | Bin | in/out | IM (predicted) | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 24 | 0.116 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i260-279o | CytoplasmicMembrane | 10 | 80 | |||||
| CYBH_ECOLI | P0AAM1 | hyaC | b0974 JW0956 | integral IM protein (SEC in IM), Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit HyaC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.112 | TMH | 0 | 10.0819 | - | 4 | 6 | N | o20-40i61-80o100-116i128-151o157-174i186-203o | CytoplasmicMembrane | 10 | |||||||
| DGCC_ECOLI | P0AAP1 | dgcC adrA yaiC | adrA yaiC | b0385 JW0376 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcC | Integral Inner Membrane | PMID: 10760159 PMID: 12673057 PMID: 16585767 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein(experimental) | SRP | SEC | yes | yes | N | 20 | 0.116 | CYT | 0 | -0.200913 | - | 5 | 5 | N | i43-61o67-85i106-130o142-167i174-193o | CytoplasmicMembrane | 10 | 22 | |||||
| YAIY_ECOLI | P0AAP7 | yaiY | b0379 JW0370 | integral IM protein (SEC in IM), YaiY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.177 | TMH | 0 | -0.122448 | - | 2 | 2 | N | i25-48o68-95i | CytoplasmicMembrane | 10 | 39 | ||||||
| YAIZ_ECOLI | P0AAQ0 | yaiZ | b0380 JW5053 | integral IM protein (SEC in IM), YaiZ | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 18 | 0.115 | TMH | 0 | 6.70305 | - | 2 | 2 | N | i12-32o38-59i | CytoplasmicMembrane | 9 | 72 | ||||||||
| YBAN_ECOLI | P0AAR5 | ybaN | b0468 JW0457 | integral IM protein (SEC in IM), YbaN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 49 | 0.172 | TMH | 0 | 11.6864 | - | 4 | 4 | N | i5-25o31-52i73-91o97-115i | CytoplasmicMembrane | 10 | 15 | ||||||
| YLAC_ECOLI | P0AAS0 | ylaC | b0458 JW5063 | integral IM protein (SEC in IM), YlaC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.106 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i36-55o61-79i | CytoplasmicMembrane | 10 | 60 | ||||||
| YBBJ_ECOLI | P0AAS3 | ybbJ | b0488 JW5065 | integral IM protein (SEC in IM), YbbJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.17 | TMH | 0 | 18.8226 | - | 3 | 3 | N | o6-23i30-49o55-72i | CytoplasmicMembrane | 10 | 12 | ||||||
| YBDG_ECOLI | P0AAT4 | ybdG mscM | mscM | b0577 JW0566 | integral IM protein (SEC in IM), Miniconductance mechanosensitive channel YbdG | Integral Inner Membrane | Mechanosensitive channel of miniconductance activity (MscM). | PMID: 15919996 PMID: 20616037 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.102 | CYT | 0 | -0.200913 | - | 5 | 5 | N | o23-48i68-87o107-127i139-160o166-183i | CytoplasmicMembrane | 10 | 11 | ||||
| YBFA_ECOLI | P0AAU2 | ybfA | b0699 JW0688 | integral IM protein (SEC in IM), YbfA | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 22 | 0.331 | TMH | 0 | 2.48449 | - | 1 | 1 | N | o12-33i | CytoplasmicMembrane | 9 | 12 | |||||||||
| YBFB_ECOLI | P0AAU5 | ybfB | b0702 JW0691 | integral IM protein (SEC in IM), YbfB | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 29 | 0.135 | TMH | 0 | 15.1783 | - | 3 | 3 | N | o6-24i45-68o80-101i | CytoplasmicMembrane | 10 | 35 | ||||||||
| YBGE_ECOLI | P0AAV0 | ybgE | b0735 JW0725 | integral IM protein (SEC in IM), YbgE | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.437 | TMH | 0 | 3.17076 | - | 3 | 3 | N | o17-34i46-67o73-96i | CytoplasmicMembrane | 10 | 27 | |||||||||
| YBHQ_ECOLI | P0AAW5 | ybhQ | b0791 JW0774 | integral IM protein (SEC in IM), YbhQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.117 | TMH | 0 | 7.89577 | - | 4 | 4 | N | i12-32o38-58i79-96o102-120i | CytoplasmicMembrane | 10 | |||||||
| ACRZ_ECOLI | P0AAW9 | acrZ ybhT | ybhT | b0762 JW5102 | integral IM protein (SEC-YidC in IM), Multidrug efflux pump accessory AcrZ | Integral Inner Membrane | Experimentally verified orientation: N(out)-C(in). Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreased. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC-YidC | no | yes | N | 21 | 0.157 | TMH | 0 | 1.49031 | - | 1 | 1 | N | i7-29o | CytoplasmicMembrane | 9 | 28 | ||||
| YBJO_ECOLI | P0AAZ0 | ybjO | b0858 JW0842 | integral IM protein (SEC in IM), YbjO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 18 | 0.159 | TMH | 0 | 4.12536 | - | 4 | 4 | N | i21-44o64-87i94-111o131-151i | CytoplasmicMembrane | 10 | 32 | ||||||
| ELYC_ECOLI | P0AB01 | elyC ycbC | ycbC | b0920 JW0903 | integral IM protein (SEC in IM), Envelope biogenesis factor ElyC | Integral Inner Membrane | Shown to play a critical role in the metabolism of the essential lipid carrier used for the biogenesis of cell wall and other bacterial surface polysaccharides. | PMCID: PMC3879167 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 60 | 0.155 | TMH | 0 | 9.49418 | - | 2 | 2 | N | o12-32i41-59o | CytoplasmicMembrane | 9 | 24 | ||||
| YCCF_ECOLI | P0AB12 | yccF | b0961 JW0944 | integral IM protein (SEC in IM), YccF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.116 | TMH | 0 | 2.25765 | - | 3 | 3 | N | i7-33o69-90i102-123o | CytoplasmicMembrane | 10 | |||||||
| YCFJ_ECOLI | P0AB35 | ycfJ | b1110 JW1096 | integral IM protein (SEC in IM), YcfJ | Integral Inner Membrane | B | - | N/A | Membrane | Membrane anchored | SRP | SEC | yes | yes | N | 36 | 0.275 | SpI | 23 | 8.09735 | - | 1 | 0 | Y | n6-17c21/22o | Unknown | 2 | ||||||||||
| YCHH_ECOLI | P0AB49 | ychH | b1205 JW1196 | integral IM protein (SEC in IM), YchH | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.123 | TMH | 0 | 12.8445 | - | 2 | 2 | N | i12-29o41-59i | CytoplasmicMembrane | 9 | 73 | |||||||||
| LAPB_ECOLI | P0AB58 | LapB yciM | yciM | b1280 JW1272 | integral IM protein (SEC in IM), polysaccharide assembly B LapB | Integral Inner Membrane | Potential TAT secreted protein. Required to maintain cell envelope integrity. Heat shock protein that is involved in the assembly of LPS PMID: 24722986 Heat shock protein that is involved in the assembly of LPS PMID: 24722986 Heat shock protein involved in the assembly of LPS. In pull-down experiments, LapA and LapB co-purified with LPS, Lpt proteins, FtsH (protease), DnaK, and DnaJ (chaperones). A specific interaction was also observed between WaaC and LapB. LapB potentially coordinates assembly of proteins involved in LPS synthesis at the plasma membrane and regulates turnover of LpxC. PMID: 25403562 | PMID: 24187084 PMID: 25403562 | Integral Inner Membrane | B | - | Soluble IM Fraction | Cell inner membrane | Periplasmic | SEC | yes | yes | N | 25 | 0.264 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-11c16/17o | Cytoplasmic | 8 | 9 | ||||||
| PNTB_ECOLI | P0AB67 | pntB | b1602 JW1594 | integral IM protein (SEC in IM), NAD(P) transhydrogenase subunit beta PntB | Integral Inner Membrane | PMID: 14660605 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.125 | TMH | 0 | 9.6368 | - | 9 | 9 | N | o6-24i36-51o57-74i86-105o125-143i163-180o186-207i214-234o240-260i | CytoplasmicMembrane | 10 | |||||||
| ARSB_ECOLI | P0AB93 | arsB arsF | arsF | b3502 JW3469 | integral IM protein (SEC in IM), Arsenical pump ArsB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 44 | 0.23 | TMH | 0 | 8.42262 | - | 11 | 10 | Y | n2-17c35/36o51-70i91-109o115-132i139-163o175-198i222-240o246-263i275-296o316-334i401-423o | CytoplasmicMembrane | 10 | ||||||
| ATP6_ECOLI | P0AB98 | atpB papD uncB | papD uncB | b3738 JW3716 | integral IM protein (SEC-YidC in IM), ATP synthase subunit a AtpB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. PMID: 10806384 | PMID: 10806384 PMID: 15263011 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | yes | yes | N | 67 | 0.123 | CYT | 0 | -0.200913 | - | 5 | 5 | N | o36-60i100-118o147-166i211-233o239-264i | CytoplasmicMembrane | 10 | 7 | ||||
| ATPF_ECOLI | P0ABA0 | atpF papF uncF | papF uncF | b3736 JW3714 | integral IM protein (SEC in IM), ATP synthase subunit b AtpF | Integral Inner Membrane | PMID: 15263011 PMID: 21541338 PMID: 6278247 | Integral Inner Membrane | B | Bin | out/in | Soluble IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | no | yes | N | 32 | 0.35 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-26i | CytoplasmicMembrane | 10 | 19 | |||||
| ATMA_ECOLI | P0ABB8 | mgtA corB mgt | corB mgt | b4242 JW4201 | integral IM protein (SEC in IM), Magnesium-transporting ATPase, P-type 1 MgtA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.122 | CYT | 0 | -0.200913 | - | 7 | 8 | N | i89-112o118-137i291-309o315-342i768-791o803-821i833-857o869-891i | CytoplasmicMembrane | 10 | 50 | |||||
| ATPZ_ECOLI | P0ABC0 | atpI uncI | uncI | b3739 JW5611 | integral IM protein (SEC-YidC in IM), ATP synthase I AtpI | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 64 | 0.113 | TMH | 0 | 4.01303 | - | 4 | 3 | Y | n14-25c30/31o40-59i71-94o100-122i | CytoplasmicMembrane | 10 | 34 | ||||
| HFLC_ECOLI | P0ABC3 | hflC hflA | hflA | b4175 JW4133 | integral IM protein (SEC in IM), Modulator of FtsH protease HflC | Integral Inner Membrane | N-terminally located transmembrane segment. PMID: 9792691 Translocation of the C-terminal domains of HflKC was retarded markedly when sodium azide was added to inhibit SecA ATPase and blocked almost completely in secY- or secD-defective mutant cells. PMID: 9792691 | PMID: 16834335 PMID: 8947034 PMID: 9792691 | Integral Inner Membrane | B | Bin | out/in | Soluble IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | Prophage Transposase (by homology to BL21) | yes | yes | N | 25 | 0.135 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-23i | Cytoplasmic | 8 | 46 | |||
| HFLK_ECOLI | P0ABC7 | hflK hflA | hflA | b4174 JW4132 | integral IM protein (SEC in IM), Modulator of FtsH protease HflK | Integral Inner Membrane | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 N-terminally located transmembrane segment. PMID: 9792691 Translocation of the C-terminal domains of HflKC was retarded markedly when sodium azide was added to inhibit SecA ATPase and blocked almost completely in secY- or secD-defective mutant cells. PMID: 9792691 | PMID: 21541338 PMID: 8947034 PMID: 9792691 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | Prophage Transposase | yes | no | N | 3 | 0.101 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i80-100o | Unknown | 5 | 20 | |||
| BETT_ECOLI | P0ABC9 | betT | b0314 JW0306 | integral IM protein (SEC in IM), High-affinity choline transport protein BetT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.108 | TMH | 0 | 11.6116 | - | 12 | 12 | N | i16-35o55-79i91-115o143-166i194-215o235-253i265-290o319-338i350-368o403-422i448-467o479-497i | CytoplasmicMembrane | 10 | |||||||
| YEAV_ECOLI | P0ABD1 | yeaV | b1801 JW5293 | integral IM protein (SEC in IM), transporter YeaV | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 19 | 0.119 | TMH | 0 | 2.33182 | - | 10 | 11 | Y | n2-13c18/19o34-59i80-104o136-158i170-191o203-221i228-246o258-277i289-308o348-371i392-412o418-438i | CytoplasmicMembrane | 10 | |||||||||
| C561_ECOLI | P0ABE5 | cybB | b1418 JW5224 | integral IM protein (SEC-YidC in IM), Cytochrome b561 CybB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 23 | 0.142 | TMH | 0 | 7.83021 | - | 4 | 4 | N | i12-33o39-62i82-106o143-162i | CytoplasmicMembrane | 10 | 31 | |||||
| PGSA_ECOLI | P0ABF8 | pgsA | b1912 JW1897 | integral IM protein (SEC in IM), CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 12558186 PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 35 | 0.17 | TMH | 0 | 12.5336 | - | 4 | 6 | N | i7-27o33-52i64-83o89-108i120-142o148-169i | CytoplasmicMembrane | 10 | 7 | |||||
| CDSA_ECOLI | P0ABG1 | cdsA cds | cds | b0175 JW5810 | integral IM protein (SEC in IM), Phosphatidate cytidylyltransferase CdsA | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. PMID: 15919996 | PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP (exp) | SEC | yes | yes | N | 30 | 0.287 | TMH | 0 | 18.3357 | - | 8 | 8 | Y | n6-13c18/19o28-44i56-73o93-113i120-141o153-171i192-210o216-234i264-282o | CytoplasmicMembrane | 10 | |||||
| FTSW_ECOLI | P0ABG4 | ftsW | b0089 JW0087 | integral IM protein (SEC in IM), Probable PG glycosyltransferase FtsW | Integral Inner Membrane | Interacts directly with FtsN. The integral membrane FtsW protein and peptidoglycan synthase PBP3 form a subcomplex. | PMID: 11807049 PMID: 12423747 PMID: 15919996 PMID: 20497333 PMID: 20847002 PMID: 9603865 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 67 | 0.137 | TMH | 0 | 10.7628 | - | 10 | 9 | Y | n15-26c32/33o48-66i87-104o110-129i175-192o198-215i222-239o307-328i340-364o376-395i | CytoplasmicMembrane | 10 | ||||||
| RODA_ECOLI | P0ABG7 | mrdB rodA | rodA | b0634 JW0629 | integral IM protein (SEC in IM), PG glycosyltransferase MrdB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.198 | TMH | 0 | 6.46483 | - | 9 | 9 | N | o20-38i50-68o74-95i136-154o160-176i183-202o263-289i310-332o338-359i | CytoplasmicMembrane | 10 | ||||||
| MRED_ECOLI | P0ABH4 | mreD | b3249 JW3218 | integral IM protein (SEC in IM), Rod shape-determining MreD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.118 | TMH | 0 | 15.556 | - | 5 | 5 | N | o6-25i37-54o74-92i104-128o134-152i | CytoplasmicMembrane | 10 | |||||||
| CORA_ECOLI | P0ABI4 | corA | b3816 JW3789 | integral IM protein (SEC-YidC in IM), Magnesium transport CorA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. Single particle electron microscopy analysis and two-dimensional crystals of PPD (large soluble periplasmic domain) of CorA indicated that E. coli CorA PPD is a pyramid-like homotetramer with a central cavity. | PMID: 15919996 PMID: 16835234 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 27 | 0.101 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i255-278o290-310i | CytoplasmicMembrane | 10 | 65 | |||||
| CYOB_ECOLI | P0ABI8 | cyoB | b0431 JW0421 | integral IM protein (SEC-YidC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 1 CyoB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 11017202 PMID: 11266632 PMID: 15919996 PMID: 22108384 PMID: 6365921 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 31 | 0.108 | TMH | 0 | 10.2812 | - | 14 | 14 | N | o16-38i59-79o103-126i146-170o190-213i233-255o275-298i310-334o346-368i380-403o415-436i457-479o491-518i593-626o | CytoplasmicMembrane | 10 | ||||||
| CYOA_ECOLI | P0ABJ1 | cyoA | b0432 JW0422 | integral IM protein (SEC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 2 CyoA | Integral Inner Membrane | Proven signal peptidase II substrate PMID: 15174130. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 The SRP interacts with the first TM of CyoA (rather than with its signal sequence) to mediate targeting of CyoA to the Sec/YidC insertion site in the inner membrane. PMID: 16481320 Efficient insertion of in vitro synthesized pre-CyoA into proteoliposomes requires YidC, SecYEG, and SecA and occurs independently of the proton motive force. PMID: 16513637 | PMID: 11017202 PMID: 11266632 PMID: 15174130 PMID: 15919657 PMID: 15919996 PMID: 16079137 PMID: 16481320 PMID: 16513637 PMID: 21541338 PMID: 6365921 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.189 | TMH | 0 | 11.3494 | - | 3 | 2 | Y | n10-22c27/28o43-67i88-108o | CytoplasmicMembrane | 10 | 19 | |||||
| CYOC_ECOLI | P0ABJ3 | cyoC | b0430 JW0420 | integral IM protein (SEC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 3 CyoC | Integral Inner Membrane | PMID: 11017202 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 14 | 0.175 | TMH | 0 | 3.44396 | - | 5 | 5 | N | i29-50o70-91i98-118o138-165i177-201o | CytoplasmicMembrane | 10 | |||||||
| CYOD_ECOLI | P0ABJ6 | cyoD | b0429 JW0419 | integral IM protein (SEC in IM), Cytochrome bo(3) ubiquinol oxidase subunit 4 CyoD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 44 | 0.15 | TMH | 0 | 14.0581 | - | 3 | 3 | N | o18-37i44-68o80-100i | CytoplasmicMembrane | 10 | |||||||
| CYDA_ECOLI | P0ABJ9 | cydA cyd-1 | cyd-1 | b0733 JW0722 | integral IM protein (SEC in IM), Cytochrome bd-I ubiquinol oxidase subunit 1 CydA | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 15013751 PMID: 15919657 PMID: 15919996 PMID: 16079137 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 37 | 0.106 | TMH | 0 | 9.54728 | - | 9 | 9 | N | o20-42i54-71o91-116i128-151o184-208i220-238o388-409i421-444o471-494i | CytoplasmicMembrane | 10 | |||||
| CYDB_ECOLI | P0ABK2 | cydB cyd-2 | cyd-2 | b0734 JW0723 | integral IM protein (SEC in IM), Cytochrome bd-I ubiquinol oxidase subunit 2 CydB | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 15013751 PMID: 15919996 PMID: 16079137 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 29 | 0.118 | TMH | 0 | 10.5085 | - | 8 | 8 | N | i9-28o77-99i119-141o161-181i202-226o264-283i290-315o335-360i | CytoplasmicMembrane | 10 | |||||
| NAPC_ECOLI | P0ABL5 | napC yejX | yejX | b2202 JW2190 | integral IM protein (SEC in IM), Cytochrome c-type NapC | Integral Inner Membrane | Nitrate reductase, napFDAGHBC, is located in the periplasm. E. coli also expresses two membrane-bound proton-translocating nitrate reductases, encoded by the narGHJI and narZYWV operons. PMID: 11844760 Electrons are fed into the NapAB dimer from a membrane-anchored tetra-heme cytochrome c,encoded by the napC gene. PMID: 8830238 PMID: 12186631 | PMID: 11844760 PMID: 12186631 PMID: 8830238 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane; Single-pass membrane protein | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 52 | 0.116 | TMH | 0 | 6.01984 | - | 1 | 1 | N | i21-44o | CytoplasmicMembrane | 10 | 14 | ||||
| CCMB_ECOLI | P0ABL8 | ccmB yejV | yejV | b2200 JW2188 | integral IM protein (SEC-YidC in IM), Heme exporter B CcmB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 20 | 0.11 | TMH | 0 | 9.26722 | - | 6 | 6 | N | i21-39o45-70i82-103o123-145i157-180o192-215i | CytoplasmicMembrane | 10 | 4 | ||||
| CCMC_ECOLI | P0ABM1 | ccmC yejT yejU | yejT yejU | b2199 JW2187 | integral IM protein (SEC-YidC in IM), Heme exporter C CcmC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. CcmC, CcmE, and heme interact directly with each other, establishing a periplasmic heme delivery pathway for cytochrome c maturation. PMID: 11384983 | PMID: 11384983 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 29 | 0.15 | TMH | 0 | 14.9856 | - | 6 | 6 | N | i21-43o63-84i91-113o133-149i161-182o202-221i | CytoplasmicMembrane | 10 | |||||
| CCMD_ECOLI | P0ABM5 | ccmD yojM | yojM | b2198 JW2186 | integral IM protein (SEC in IM), Heme exporter D CcmD | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 7 | 0.153 | TMH | 0 | 3.24028 | - | 1 | 1 | N | o12-37i | CytoplasmicMembrane | 9 | 66 | |||||||
| CCMH_ECOLI | P0ABM9 | ccmH yejP | yejP | b2194 JW2182 | integral IM protein (SEC in IM), Cytochrome c-type biogenesis CcmH | Integral Inner Membrane | Might be is co-translationally translocated through Sec translocon. CcmH is a periplasm-resident oxidoreductase anchored to the inner membrane by two transmembrane segments. Both N- and C-terminal domains are located and function in the periplasmic compartment. PMID: 22789558 Potential substrate for the SRP pathway. When fused to cytoplasmic protein thioredoxin promotes signal recognition particle-dependent translocation PMID: 15838024 | PMID: 15838024 PMID: 15919996 PMID: 22789558 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | Y | 19 | 0.795 | SpI | 18 | 8.87226 | - | 3 | 2 | Y | n3-13c18/19o102-120i147-166o | CytoplasmicMembrane | 10 | 41 | ||||
| KDGL_ECOLI | P0ABN1 | dgkA | b4042 JW4002 | integral IM protein (SEC in IM), Diacylglycerol kinase DgkA | Integral Inner Membrane | PMID: 15919996 PMID: 2984194 PMID: 8071224 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 54 | 0.112 | CYT | 0 | -0.200913 | - | 2 | 3 | N | i30-51o57-80i100-121o | CytoplasmicMembrane | 10 | 31 | ||||||
| DCUA_ECOLI | P0ABN5 | dcuA genA | genA | b4138 JW5735 | integral IM protein (SEC in IM), Anaerobic C4-dicarboxylate transporter DcuA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 28 | 0.186 | TMH | 0 | 7.74612 | - | 11 | 11 | N | o6-38i45-66o86-109i130-152o164-190i225-243o255-277i289-306o326-345i357-381o410-431i | CytoplasmicMembrane | 10 | ||||||
| DCUB_ECOLI | P0ABN9 | dcuB genF | genF | b4123 JW4084 | integral IM protein (SEC in IM), Anaerobic C4-dicarboxylate transporter DcuB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 68 | 0.125 | TMH | 0 | 8.74519 | - | 11 | 10 | Y | n2-13c17/18o27-44i51-71o91-118i139-162o174-195i236-254o266-288i300-318o342-372i421-445o | CytoplasmicMembrane | 10 | ||||||
| DCUC_ECOLI | P0ABP3 | dcuC | b0621 JW0613/JW0616 | integral IM protein (SEC in IM), Anaerobic C4-dicarboxylate transporter DcuC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 56 | 0.117 | TMH | 0 | 0.537839 | - | 12 | 12 | N | i5-22o28-46i79-98o118-144i156-175o195-218i238-260o266-288i309-333o339-363i406-424o436-458i | CytoplasmicMembrane | 10 | 3 | ||||||
| DEDA_ECOLI | P0ABP6 | dedA | b2317 JW2314 | integral IM protein (SEC-YidC in IM) of DedA family, DedA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 22108384 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 20 | 0.121 | CYT | 0 | -0.200913 | - | 4 | 4 | N | i27-49o69-92i156-178o190-208i | CytoplasmicMembrane | 10 | ||||||
| YIJE_ECOLI | P0ABT8 | yijE | b3943 JW5557 | integral IM protein (SEC in IM), Probable cystine transporter YijE YijE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.12 | TMH | 0 | 7.7108 | - | 10 | 10 | N | i12-29o35-59i71-91o97-118i125-141o153-171i183-205o217-239i246-266o272-289i | CytoplasmicMembrane | 10 | |||||||
| EXBB_ECOLI | P0ABU7 | exbB | b3006 JW2974 | integral IM protein (SEC in IM), Biopolymer transport ExbB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.153 | CYT | 0 | -0.200913 | - | 3 | 3 | N | o21-43i132-157o177-198i | CytoplasmicMembrane | 10 | 14 | ||||||
| TOLQ_ECOLI | P0ABU9 | tolQ fii | fii | b0737 JW0727 | integral IM protein (SEC in IM), Tol-Pal system TolQ | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. PMID: 8300535 PMID: 8331075 | PMID: 15919996 PMID: 8300535 PMID: 8331075 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP (exp) | SEC | yes | yes | N | 34 | 0.244 | TMH | 0 | 2.05597 | - | 3 | 3 | N | o15-35i139-159o171-192i | CytoplasmicMembrane | 10 | 9 | ||||
| EXBD_ECOLI | P0ABV2 | exbD | b3005 JW2973 | integral IM protein (SEC in IM), Biopolymer transport ExbD | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Single-pass type II membrane protein | Membrane anchored | SRP | SEC | yes | yes | N | 42 | 0.15 | TMH | 0 | 0.162291 | - | 1 | 1 | N | o20-41i | CytoplasmicMembrane | 9 | 47 | ||||||||
| TOLR_ECOLI | P0ABV6 | tolR | b0738 JW0728 | integral IM protein (SEC in IM), Tol-Pal system TolR | Integral Inner Membrane | PMID: 7744737 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 37 | 0.197 | TMH | 0 | 0.527259 | - | 1 | 1 | N | i21-39o | CytoplasmicMembrane | 9 | 23 | ||||||
| FLIL_ECOLI | P0ABX8 | fliL cheC1 fla AI fla QI | cheC1 fla AI fla QI | b1944 JW1928 | integral IM protein (SEC in IM), FliL | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Outer membrane Lipoprotein | SRP | SEC | no | yes | N | 43 | 0.268 | SpII | 26 | 10.5269 | Pos+2=A | 1 | 1 | N | i14-35o | CytoplasmicMembrane | 10 | 35 | |||||||
| FLIP_ECOLI | P0AC05 | fliP flaR | flaR | b1948 JW1932 | Flagellar integral IM protein (SEC in IM), biosynthetic FliP | Integral Inner Membrane | A cleavable signal peptide is required for the full function of FliP protein. | PMID: 15194505 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | flagellum | SRP | SEC | no | yes | Y | 22 | 0.692 | TMH | 0 | 13.015 | - | 5 | 4 | Y | n4-15c21/22o45-74i86-105o185-211i223-244o | CytoplasmicMembrane | 10 | ||||
| FLIQ_ECOLI | P0AC07 | fliQ flaQ | flaQ | b1949 JW1933 | Flagellar integral IM protein (SEC in IM), biosynthetic FliQ | Integral Inner Membrane | B | Binout | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | flagellum | SRP | SEC | no | yes | N | 41 | 0.283 | TMH | 0 | 14.373 | - | 2 | 1 | Y | n16-35c40/41o56-74i | CytoplasmicMembrane | 10 | 30 | ||||||
| FOCA_ECOLI | P0AC23 | focA ycaE | ycaE | b0904 JW0887 | integral IM protein (SEC in IM), Probable formate transporter 1 FocA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.124 | TMH | 0 | 1.35944 | - | 6 | 6 | N | i35-55o75-98i118-141o161-180i192-212o255-277i | CytoplasmicMembrane | 10 | ||||||
| NIRC_ECOLI | P0AC26 | nirC | b3367 JW3330 | integral IM protein (SEC in IM), Nitrite transporter NirC NirC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.428 | TMH | 0 | 4.72286 | - | 6 | 6 | N | i25-47o59-80i101-126o146-169i181-206o226-248i | CytoplasmicMembrane | 10 | |||||||
| FTSX_ECOLI | P0AC30 | ftsX ftsS | ftsS | b3462 JW3427 | integral IM protein (SEC in IM), Cell division FtsX | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 10048040 PMID: 14729705 PMID: 15919996 PMID: 3323846 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 39 | 0.105 | CYT | 0 | -0.200913 | - | 4 | 4 | N | o72-95i214-240o272-290i323-342o | CytoplasmicMembrane | 10 | 23 | ||||
| DHSD_ECOLI | P0AC44 | sdhD | b0722 JW0712 | integral IM protein (SEC in IM), Succinate dehydrogenase hydrophobic anchor subunit SdhD | Integral Inner Membrane | PArt of colisuccinate dehydrogenase (SQR) composed of two hydrophilic subunits, a flavoprotein (SdhA) and iron-sulfur protein (SdhB) subunit, and two hydrophobic membrane anchor subunits, SdhC and SdhD. | PMID: 11266632 PMID: 12560550 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.133 | TMH | 0 | 10.7371 | - | 3 | 3 | N | i17-39o59-80i92-113o | CytoplasmicMembrane | 10 | 44 | |||||
| KDTA_ECOLI | P0AC75 | waaA kdtA | kdtA | b3633 JW3608 | integral IM protein (SEC in IM), 3-deoxy-D-manno-octulosonic acid transferase WaaA | Integral Inner Membrane | Involved in lipopolysaccharide biosynthesis PMID: 2651435 PMID: 1577828. Embedded in the cytoplasmic face of the inner membrane, WaaA catalyzes the transfer of 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) to the lipid A precursor of LPS (in Aquifex aeolicus) PMID: 22474366. | PMID: 1577828 PMID: 15866922 PMID: 19275539 PMID: 22474366 PMID: 2651435 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 64 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o6-23i | Unknown | 2 | 15 | ||||
| WECA_ECOLI | P0AC78 | wecA rfe | rfe | b3784 JW3758 | integral IM protein (SEC in IM), Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase WecA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.115 | CYT | 0 | -0.200913 | - | 11 | 11 | N | o6-24i45-66o72-89i101-119o131-149i161-179o185-206i213-232o244-263i294-315o321-342i | CytoplasmicMembrane | 10 | ||||||
| GNTP_ECOLI | P0AC94 | gntP yjiB | yjiB | b4321 JW4284 | integral IM protein (SEC in IM), High-affinity gluconate transporter GntP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.178 | TMH | 0 | 7.17039 | - | 13 | 12 | N | i7-23o29-49i61-79o99-132i139-157o177-201i222-249o261-280i301-320o340-373i380-402o422-446i | CytoplasmicMembrane | 10 | ||||||
| GNTU_ECOLI | P0AC96 | gntU | b4476 JW5686 | integral IM protein (SEC in IM), Low-affinity gluconate transporter GntU | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | yes | N | 31 | 0.139 | TMH | 0 | 10.5274 | - | 13 | 12 | N | i5-22o28-47i59-80o100-128i140-163o175-197i226-250o262-282i303-320o340-373i385-408o428-445i | CytoplasmicMembrane | 10 | ||||||
| SATP_ECOLI | P0AC98 | satP yaaH | yaaH | b0010 JW0009 | integral IM protein (SEC in IM), Succinate-acetate/proton symporter SatP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.122 | TMH | 0 | 9.07966 | - | 6 | 6 | N | i12-31o37-56i63-84o96-116i123-143o149-169i | CytoplasmicMembrane | 10 | ||||||
| HEMY_ECOLI | P0ACB7 | hemY | b3802 JW3774 | integral IM protein (SEC in IM), HemY | Integral Inner Membrane | Trigger factor-sensitive aggregation. | PMID: 15919996 PMID: 19737520 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP,TF | SEC | yes | yes | N | 23 | 0.235 | TMH | 0 | 10.5296 | - | 2 | 1 | Y | n4-17c26/27o42-62i | CytoplasmicMembrane | 10 | 19 | |||||
| LPXL_ECOLI | P0ACV0 | lpxL htrB waaM | htrB waaM | b1054 JW1041 | integral IM protein (SEC in IM), Lipid A biosynthesis lauroyltransferase LpxL | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 20 | 0.104 | TMH | 0 | 1.65586 | - | 1 | 2 | N | i12-30o36-52i | CytoplasmicMembrane | 10 | 11 | |||||||
| LPXP_ECOLI | P0ACV2 | lpxP ddg | ddg | b2378 JW2375 | integral IM protein (SEC-YidC in IM), Lipid A biosynthesis palmitoleoyltransferase LpxP | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 22108384 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC-YidC | yes | yes | N | 49 | 0.166 | TMH | 0 | 1.68704 | - | 1 | 1 | N | o20-46i | CytoplasmicMembrane | 9 | 9 | ||||
| LAPA_ECOLI | P0ACV4 | LapA yciS | yciS | b1279 JW1271 | integral IM protein (SEC in IM), polysaccharide assembly A LapA | Integral Inner Membrane | YciS (LapA) possibly participates both in lateral elongation of peptidoglycan and septum formation.PMID: 24722986 C-terminal tagging with the alkaline phosphatase and green fluorescent protein in order to define the periplasmic or cytoplasmic locations of the C termini. PMID: 15919996 Heat shock protein involved in the assembly of LPS. In pull-down experiments, LapA and LapB co-purified with LPS, Lpt proteins, FtsH (protease), DnaK, and DnaJ (chaperones). PMID: 25403562 | PMID: 15919996 PMID: 25403562 | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.34 | TMH | 0 | 11.7404 | - | 2 | 1 | Y | n4-16c21/22o45-67i | CytoplasmicMembrane | 10 | 36 | ||||
| YDGC_ECOLI | P0ACX0 | ydgC | b1607 JW1599 | integral IM protein (SEC in IM), YdgC | Integral Inner Membrane | Dual topology membrane protein: can insert into the membrane in both directions. PMID: 15919996 | PMID: 15919996 PMID: 16429150 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | in/out, out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.169 | TMH | 0 | 3.73379 | - | 4 | 3 | Y | n7-17c21/22o31-47i59-79o85-108i | CytoplasmicMembrane | 10 | 23 | |||||
| YEAL_ECOLI | P0ACY6 | yeaL | b1789 JW1778 | integral IM protein (SEC in IM), UPF0756 YeaL | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 25 | 0.203 | TMH | 0 | 8.39191 | - | 4 | 4 | Y | n4-12c16/17o26-46i53-71o83-100i112-145o | CytoplasmicMembrane | 10 | |||||||||
| YEBS_ECOLI | P0AD03 | yebS | b1833 JW1822 | integral IM protein (SEC in IM), Intertransport YebS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 57 | 0.112 | CYT | 0 | -0.200913 | - | 8 | 8 | N | i66-84o120-141i162-179o185-208i266-291o311-339i360-378o384-406i | CytoplasmicMembrane | 10 | |||||||
| BTSS_ECOLI | P0AD14 | btsS yehU | yehU | b2126 JW5353 | integral IM protein (SEC in IM), Sensor histidine kinase BtsS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.144 | TMH | 0 | 6.36838 | - | 6 | 6 | N | i7-24o44-62i74-93o105-129i141-163o175-195i | CytoplasmicMembrane | 10 | 2 | |||||
| YOHC_ECOLI | P0AD17 | yohC | b2135 JW5356 | integral IM protein (SEC in IM), YohC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 45 | 0.135 | TMH | 0 | 2.03436 | - | 5 | 5 | N | i33-53o65-91i103-122o128-149i170-190o | CytoplasmicMembrane | 10 | 16 | ||||||
| YOHK_ECOLI | P0AD19 | yohK | b2142 JW2130 | integral IM protein (SEC in IM), YohK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 24 | 0.211 | TMH | 0 | 1.42711 | - | 6 | 4 | Y | n7-18c23/24o33-52i91-112o132-162i206-230o | CytoplasmicMembrane | 10 | |||||||
| YEJM_ECOLI | P0AD27 | yejM yejN | yejN | b2188 JW2176 | integral IM protein (SEC in IM), YejM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 68 | 0.133 | TMH | 0 | 14.6981 | - | 5 | 5 | N | i21-39o51-73i85-103o135-157i169-191o | CytoplasmicMembrane | 10 | 2 | |||||
| YFCA_ECOLI | P0AD30 | yfcA | b2327 JW2324 | integral IM protein (SEC in IM), Probable transporter YfcA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 54 | 0.218 | TMH | 0 | 11.5476 | - | 7 | 8 | N | i7-28o53-73i85-105o111-127i139-158o164-183i195-217o237-255i | CytoplasmicMembrane | 10 | |||||||
| PGPC_ECOLI | P0AD42 | pgpC yfhB | yfhB | b2560 JW5408 | integral IM protein (SEC in IM), Phosphatidylglycerophosphatase C PgpC | Integral Inner Membrane | Potential substrate of periplasmic chaperone YfgM. PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 25403562 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | YfgM | no | yes | N | 52 | 0.106 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o36-54i | CytoplasmicMembrane | 9 | 8 | |||
| YPHA_ECOLI | P0AD47 | yphA | b2543 JW2527 | integral IM protein (SEC in IM), YphA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 58 | 0.13 | TMH | 0 | 13.6817 | - | 4 | 4 | N | i12-33o53-74i81-100o120-137i | CytoplasmicMembrane | 10 | |||||||
| MRDA_ECOLI | P0AD65 | mrdA pbpA | pbpA | b0635 JW0630 | integral IM protein (SEC in IM), PG D,D-transpeptidase MrdA | Integral Inner Membrane | PMID: 1103132 PMID: 15919657 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Soluble IM Fraction, Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 37 | 0.174 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i21-40o | CytoplasmicMembrane | 9 | 8 | |||||
| FTSI_ECOLI | P0AD68 | ftsI pbpB | pbpB | b0084 JW0082 | integral IM protein (SEC in IM), PG D,D-transpeptidase FtsI | Integral Inner Membrane | The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein. Localizes to potential division sites in filamentous cells. Interacts directly with FtsN and ZapA. The integral membrane FtsW protein and peptidoglycan synthase PBP3 form a subcomplex. | PMID: 11703663 PMID: 20497333 PMID: 20847002 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 37 | 0.141 | SpI | 45 | 3.45111 | - | 1 | 1 | N | i20-44o | CytoplasmicMembrane | 9 | 22 | ||||
| BRNQ_ECOLI | P0AD99 | brnQ | b0401 JW0391 | integral IM protein (SEC-YidC in IM), Branched-chain amino acid transport system 2 carrier BrnQ | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 25 | 0.304 | TMH | 0 | 15.0757 | - | 12 | 12 | N | i12-29o41-64i76-98o118-138i150-171o191-212i224-246o281-307i314-333o339-359i371-389o409-426i | CytoplasmicMembrane | 10 | ||||||
| LOLC_ECOLI | P0ADC3 | lolC ycfU | ycfU | b1116 JW5161 | integral IM protein (SEC in IM), Lipoprotein-releasing system TM protein LolC | Integral Inner Membrane | PMID: 10783239 PMID: 15276320 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 19 | 0.179 | TMH | 0 | 2.37377 | - | 4 | 5 | N | o25-48i269-290o310-336i343-360o366-385i | CytoplasmicMembrane | 10 | 29 | |||||
| LPTG_ECOLI | P0ADC6 | lptG yjgQ | yjgQ | b4262 JW5760 | integral IM protein (SEC in IM), polysaccharide export system permease LptG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.105 | TMH | 0 | 4.7678 | - | 6 | 6 | N | i12-33o66-84i105-125o279-298i305-322o334-356i | CytoplasmicMembrane | 10 | 9 | |||||
| YJJB_ECOLI | P0ADD2 | yjjB | b4363 JW4327 | integral IM protein (SEC in IM), UPF0442 YjjB | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.153 | TMH | 0 | 7.02974 | - | 3 | 5 | N | o6-27i34-52o58-75i87-109o129-151i | CytoplasmicMembrane | 10 | 11 | ||||||||
| YJJP_ECOLI | P0ADD5 | yjjP | b4364 JW5796 | integral IM protein (SEC in IM), YjjP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.178 | CYT | 0 | -0.200913 | - | 3 | 5 | N | i114-135o141-158i170-189o195-214i226-252o | CytoplasmicMembrane | 10 | 16 | ||||||
| YHHN_ECOLI | P0ADI9 | yhhN | b3468 JW3433 | integral IM protein (SEC in IM), YhhN | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.165 | TMH | 0 | 7.64349 | - | 6 | 6 | Y | n3-14c18/19o34-64i76-96o102-123i130-152o158-177i189-207o | CytoplasmicMembrane | 10 | |||||||||
| BCSF_ECOLI | P0ADJ5 | bcsF yhjT | yhjT | b3537 JW5663 | integral IM protein (SEC in IM), Cellulose biosynthesis BcsF | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 26 | 0.211 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-25i | Unknown | 2 | 68 | |||||||
| YIAA_ECOLI | P0ADJ8 | yiaA | b3562 JW3534 | integral IM protein (SEC in IM), YiaA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 22 | 0.118 | TMH | 0 | 7.26426 | - | 4 | 4 | N | i12-30o42-62i74-94o106-125i | CytoplasmicMembrane | 10 | 59 | ||||||
| YIAW_ECOLI | P0ADK4 | yiaW | b3587 JW3559 | integral IM protein (SEC in IM), YiaW | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.107 | TMH | 0 | 11.1792 | - | 2 | 2 | N | o6-25i46-66o | CytoplasmicMembrane | 10 | 20 | ||||||
| NEPI_ECOLI | P0ADL1 | nepI yicM | yicM | b3662 JW5938 | integral IM protein (SEC in IM), Purine ribonucleoside efflux pump NepI NepI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.151 | TMH | 0 | 8.80109 | - | 12 | 12 | N | i21-44o56-75i87-106o112-133i145-164o176-196i217-239o254-275i282-301o307-329i341-363o369-389i | CytoplasmicMembrane | 10 | ||||||
| YICN_ECOLI | P0ADL3 | yicN | b3663 JW5637 | integral IM protein (SEC in IM), YicN | Echolocation says Membrane anchored, one or two TMH predicted, if signal peptide is also predicted these TMH(s) are not removed as it is probably not cleaved. | Integral Inner Membrane | B | - | N/A | Membrane anchored | SRP | SEC | yes | yes | N | 27 | 0.132 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n6-17c21/22o | Unknown | 2 | 23 | |||||||||
| YIDG_ECOLI | P0ADL6 | yidG | b3675 JW3651 | integral IM protein (SEC in IM), YidG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.125 | TMH | 0 | 5.45771 | - | 3 | 3 | N | i21-39o45-65i91-116o | CytoplasmicMembrane | 10 | 21 | ||||||
| YIDH_ECOLI | P0ADM0 | yidH | b3676 JW3652 | integral IM protein (SEC in IM), YidH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.135 | TMH | 0 | 1.23486 | - | 3 | 3 | N | i21-39o54-72i93-114o | CytoplasmicMembrane | 10 | 20 | ||||||
| YIGM_ECOLI | P0ADP5 | yigM | b3827 JW3803 | integral IM protein (SEC in IM), Biotin transporter YigM | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 20 | 0.164 | TMH | 0 | 6.74192 | - | 10 | 9 | Y | n2-13c19/20o29-47i59-81o87-105i112-130o136-158i170-190o202-222i234-253o259-276i | CytoplasmicMembrane | 10 | |||||||||
| YIID_ECOLI | P0ADQ2 | yiiD | b3888 JW3859 | integral IM protein (SEC in IM), YiiD | Integral Inner Membrane | Copurifies with trigger factor in pull down assays. | PMID: 19737520 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cytoplasmic | SRP,TF | SEC | no | yes | N | 29 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o219-240i | Cytoplasmic | 8 | 53 | ||||||
| YGAM_ECOLI | P0ADQ7 | ygaM | b2672 JW2647 | integral IM protein (SEC in IM), YgaM | Integral Inner Membrane | YgaM is paralogous to YqjD and binds to ribsomes in a similar manner to YqjD. PMID: 22661687 | PMID: 22661687 | Integral Inner Membrane | B | Bin | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 40 | 0.127 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i87-106o | Unknown | 2 | 50 | |||||
| YQAA_ECOLI | P0ADR0 | yqaA | b2689 JW2664 | integral IM protein (SEC in IM), YqaA | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. PMID: 15919996 | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 19 | 0.233 | TMH | 0 | 5.40517 | - | 4 | 3 | Y | n4-12c17/18o41-65i86-110o116-141i | CytoplasmicMembrane | 10 | 4 | |||||
| YGDD_ECOLI | P0ADR2 | ygdD | b2807 JW2778 | integral IM protein (SEC in IM), UPF0382 YgdD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.249 | TMH | 0 | 14.4685 | - | 4 | 3 | Y | n7-20c24/25o40-61i68-91o97-121i | CytoplasmicMembrane | 10 | |||||||
| YGIM_ECOLI | P0ADT8 | ygiM | b3055 JW3027 | integral IM protein (SEC in IM), YgiM | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Membrane | Membrane anchored | SRP | SEC | yes | yes | Y | 23 | 0.542 | SpI | 22 | 18.2018 | - | 1 | 1 | Y | n6-17c22/23o173-195i | Unknown | 2 | 12 | ||||||||
| LPTC_ECOLI | P0ADV9 | lptC yrbK | yrbK | b3199 JW3166 | integral IM protein (SEC in IM), polysaccharide export system LptC | Integral Inner Membrane | Echolocation says Signal peptide may be membrane anchored or cleaved and the protein therefore exported (signalP score near threshold) | PMID: 18424520 PMID: 20720015 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 26 | 0.212 | SpI | 25 | 7.46611 | - | 1 | 0 | Y | n7-18c27/28o | Unknown | 2 | 51 | ||||
| YHCB_ECOLI | P0ADW3 | yhcB | b3233 JW5539 | integral IM protein (SEC in IM), YhcB | Integral Inner Membrane | Has been isolated from inner membrane preparations in a complex with one subunit each of CydA and CydB, suggesting that YhcB is in fact a subunit of the cytochrome bd ubiquinol oxidase complex. YhcB was demonstrated to interact with RodZ as well as several other proteins involved in cell shape maintenance and an inner membrane protein YciS of unknown function, using bacterial two-hybrid system.These observations seem to indicate that YhcB is involved in the biogenesis of cell envelope and the maintenance of cell shape together with RodZ. <a href="http:/ | PMID: 15919657 PMID: 16079137 PMID: 21210718 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 21 | 0.134 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-24i | CytoplasmicMembrane | 9 | 83 | |||||
| PPID_ECOLI | P0ADY1 | ppiD ybaU | ybaU | b0441 JW0431 | integral IM protein (SEC in IM), Peptidyl-prolyl cis-trans isomerase D PpiD | Integral Inner Membrane | By in vivo and in vitro site-directed cross-linking, it has been demostrated that the periplasmic chaperone PpiD is located in front of the lateral gate of SecY, through which transmembrane domains exit the SecY channel. Blue native PAGE analyses verify the presence of a SecYEG-PpiD complex in native Escherichia coli membranes. PMID: 24951590 Consistent with a coupling between translocation across the SecYEG translocon and folding by periplasmic chaperones, a lack of PpiD retards the release of a translocating outer membrane protein into the periplasm. PMID: 18439025 | PMID: 16079137 PMID: 18439025 PMID: 24951590 PMID: 9670013 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.199 | TMH | 0 | 3.55242 | - | 1 | 1 | N | i12-35o | CytoplasmicMembrane | 10 | 52 | ||||
| YAJC_ECOLI | P0ADZ7 | yajC | b0407 JW0397 | integral IM protein (SEC in IM), Sec translocon accessory complex subunit YajC | Integral Inner Membrane | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 16079137 PMID: 21541338 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 17 | 0.156 | TMH | 0 | -0.000234246 | - | 1 | 1 | N | o20-39i | CytoplasmicMembrane | 10 | 41 | |||||
| AMPE_ECOLI | P0AE14 | ampE | b0111 JW0107 | integral IM protein (SEC in IM), AmpE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 23 | 0.115 | CYT | 0 | -0.200913 | - | 4 | 4 | Y | n2-12c16/17o40-58i65-85o148-168i266-283o | CytoplasmicMembrane | 10 | 3 | ||||||
| AMPG_ECOLI | P0AE16 | ampG | b0433 JW0423 | integral IM protein (SEC-YidC in IM), AmpG | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 38 | 0.305 | TMH | 0 | 12.6077 | - | 14 | 14 | N | i15-38o44-61i82-101o107-131i143-165o177-195i225-250o262-281i288-309o321-342i354-376o382-402i423-445o465-485i | CytoplasmicMembrane | 10 | ||||||
| ARAE_ECOLI | P0AE24 | araE | b2841 JW2809 | integral IM protein (SEC-YidC in IM), Arabinose-proton symporter AraE | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 45 | 0.136 | TMH | 0 | 7.37397 | - | 12 | 12 | N | i23-51o63-84i91-110o116-137i149-167o179-198i258-281o297-317i329-348o360-384i405-422o428-446i | CytoplasmicMembrane | 10 | ||||||
| ARAH_ECOLI | P0AE26 | araH | b4460 JW1887 | integral IM protein (SEC-YidC in IM), L-arabinose transport system permease AraH | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | pseudogene (Ochman & Davalos, 2006) | no | yes | N | 47 | 0.147 | TMH | 0 | 13.0464 | - | 9 | 10 | N | i21-42o54-72i79-96o102-124i131-150o170-191i222-240o252-269i276-295o301-317i | CytoplasmicMembrane | 10 | |||||
| ARTM_ECOLI | P0AE30 | artM | b0861 JW0845 | integral IM protein (SEC-YidC in IM), Arginine ABC transporter permease ArtM | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 27 | 0.106 | TMH | 0 | 12.0162 | - | 5 | 5 | N | o20-39i51-70o82-100i155-176o188-211i | CytoplasmicMembrane | 10 | ||||||
| ARTQ_ECOLI | P0AE34 | artQ | b0862 JW0846 | integral IM protein (SEC-YidC in IM), Arginine ABC transporter permease ArtQ | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 30 | 0.173 | TMH | 0 | 17.1037 | - | 4 | 5 | N | o12-35i42-68o101-118i161-182o202-223i | CytoplasmicMembrane | 10 | 26 | |||||
| YQAE_ECOLI | P0AE42 | yqaE | b2666 JW2641 | integral IM protein (SEC in IM), UPF0057 YqaE | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.14 | TMH | 0 | 6.73627 | - | 2 | 1 | N | o23-48i | CytoplasmicMembrane | 10 | |||||||||
| YTFL_ECOLI | P0AE45 | ytfL | b4218 JW4177 | integral IM protein (SEC in IM), UPF0053 YtfL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.622 | SpI | 26 | 9.49148 | - | 4 | 3 | Y | n5-18c26/27o56-80i100-119o139-162i | CytoplasmicMembrane | 10 | 48 | ||||||
| CITT_ECOLI | P0AE74 | citT ybdS | ybdS | b0612 JW0604 | integral IM protein (SEC in IM), Citrate/succinate antiporter CitT | Integral Inner Membrane | PMID: 9696764 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 58 | 0.164 | TMH | 0 | 13.6692 | - | 13 | 14 | N | i7-27o33-50i57-74o94-117i138-155o161-178i190-213o233-259i288-304o310-329i341-361o381-412i424-443o463-486i | CytoplasmicMembrane | 10 | ||||||
| CPXA_ECOLI | P0AE82 | cpxA ecfB eup ssd | ecfB eup ssd | b3911 JW3882 | integral IM protein (SEC-YidC in IM), Sensor histidine kinase CpxA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 19 | 0.111 | TMH | 0 | 1.20569 | - | 2 | 2 | N | o6-27i165-184o | CytoplasmicMembrane | 10 | 16 | ||||
| CYOE_ECOLI | P0AEA5 | cyoE | b0428 JW0418 | integral IM protein (SEC in IM), Protoheme IX farnesyltransferase CyoE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 58 | 0.11 | TMH | 0 | 2.59686 | - | 9 | 9 | N | i12-30o36-60i80-102o108-127i134-156o162-183i209-227o233-252i264-285o | CytoplasmicMembrane | 10 | |||||||
| CYSW_ECOLI | P0AEB0 | cysW | b2423 JW2416 | integral IM protein (SEC in IM), Sulfate transport system permease CysW | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.154 | TMH | 0 | 13.7791 | - | 6 | 6 | N | i20-43o63-89i101-124o144-162i202-228o248-268i | CytoplasmicMembrane | 10 | 52 | ||||||
| YNAI_ECOLI | P0AEB5 | ynaI | b1330 JW1323 | integral IM protein (SEC in IM), Low conductance mechanosensitive channel YnaI | Integral Inner Membrane | PMID: 15919996 PMID: 22874652 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.127 | TMH | 0 | 7.65863 | - | 4 | 5 | N | o12-30i42-65o77-96i117-134o140-159i | CytoplasmicMembrane | 10 | 14 | ||||||
| YOAE_ECOLI | P0AEC0 | yoaE | b1816 JW1805 | integral IM protein (SEC in IM), UPF0053 YoaE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.115 | TMH | 0 | 1.99313 | - | 7 | 7 | N | o12-36i48-69o81-101i122-148o154-172i184-207o213-231i | CytoplasmicMembrane | 10 | 10 | ||||||
| ARCB_ECOLI | P0AEC3 | arcB | b3210 JW5536 | integral IM protein (SEC in IM), Aerobic respiration control sensor ArcB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.18 | TMH | 0 | 9.51619 | - | 2 | 2 | N | o20-46i58-77o | CytoplasmicMembrane | 10 | |||||||
| BARA_ECOLI | P0AEC5 | barA | b2786 JW2757 | integral IM protein (SEC-YidC in IM), Signal transduction histidine-kinase BarA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 34 | 0.123 | TMH | 0 | 7.64299 | - | 2 | 2 | N | o12-31i177-199o | CytoplasmicMembrane | 10 | 56 | |||||
| DCUS_ECOLI | P0AEC8 | dcuS yjdH | yjdH | b4125 JW4086 | integral IM protein (SEC-YidC in IM), Sensor histidine kinase DcuS | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 48 | 0.105 | TMH | 0 | 5.80308 | - | 2 | 2 | N | i21-41o183-205i | CytoplasmicMembrane | 10 | 35 | ||||
| DPPB_ECOLI | P0AEF8 | dppB | b3543 JW3512 | integral IM protein (SEC in IM), Dipeptide transport system permease DppB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.168 | TMH | 0 | 6.13051 | - | 6 | 6 | N | i9-30o100-123i135-160o201-221i259-285o305-331i | CytoplasmicMembrane | 10 | |||||||
| DPPC_ECOLI | P0AEG1 | dppC | b3542 JW3511 | integral IM protein (SEC-YidC in IM), Dipeptide transport system permease DppC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 59 | 0.13 | TMH | 0 | 0.391748 | - | 5 | 5 | N | o32-53i102-127o147-173i215-244o264-287i | CytoplasmicMembrane | 10 | 4 | |||||
| RSEP_ECOLI | P0AEH1 | rseP ecfE yaeL | ecfE yaeL | b0176 JW0171 | integral IM protein (SEC in IM), Regulator of sigma-E protease RseP | Integral Inner Membrane | Fluorescent fusions of RseP have been monitored via fluorescence microscopy. RseP has been found to generally associated with the membrane. | PMID: 11689431 PMID: 11750129 PMID: 11867724 PMID: 15919996 PMID: 17272300 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.109 | TMH | 0 | 3.00034 | - | 4 | 4 | N | o6-29i98-119o376-396i426-444o | CytoplasmicMembrane | 10 | 16 | ||||
| ELAB_ECOLI | P0AEH5 | elaB yfbD | yfbD | b2266 JW2261 | integral IM protein (SEC in IM), ElaB | Integral Inner Membrane | ElaB is an YqjD paralog and also has transmembrane motif at the C-terminal region. ElaB is an YqjD paralog and also has transmembrane motif at the C-terminal region. Probably binds to the membrane and ribosomes in a manner similar to that of YqjD PMID: 22661687. | PMID: 22661687 | Integral Inner Membrane | B | Bout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 33 | 0.125 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o81-99i | Unknown | 2 | 99 | ||||
| YJIG_ECOLI | P0AEH8 | yjiG | b4329 JW4292 | integral IM protein (SEC in IM), YjiG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 36 | 0.157 | TMH | 0 | 2.83449 | - | 3 | 4 | N | i21-39o59-77i89-110o130-152i | CytoplasmicMembrane | 10 | 2 | ||||||
| EMRB_ECOLI | P0AEJ0 | emrB | b2686 JW2661 | integral IM protein (SEC-YidC in IM), Multidrug export EmrB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. PMID: 15919996 | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | yes | yes | N | 36 | 0.208 | TMH | 0 | 5.07213 | - | 13 | 13 | N | i12-33o53-72i81-100o106-128i140-161o167-189i201-220o232-251i272-291o303-324i336-353o365-390i480-498o | CytoplasmicMembrane | 10 | ||||||
| ENVZ_ECOLI | P0AEJ4 | envZ ompB perA tpo | ompB perA tpo | b3404 JW3367 | integral IM protein (SEC in IM), Osmolarity sensor EnvZ | Integral Inner Membrane | Contains HAMP an intrinsically disordered domain. EnvZ HAMP domain by itself is unable to form a stable structure and that this structural fragility may be important for its role in signal transduction. | PMID: 15522865 PMID: 15919996 PMID: 17635923 PMID: 2668953 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.263 | TMH | 0 | 7.11037 | - | 2 | 2 | N | i12-39o160-179i | CytoplasmicMembrane | 10 | |||||
| FDNI_ECOLI | P0AEK7 | fdnI | b1476 JW1472 | integral IM protein (SEC in IM), Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit FdnI | Integral Inner Membrane | PMID: 11266632 PMID: 11884747 PMID: 11929547 PMID: 15342602 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 37 | 0.156 | TMH | 0 | 22.1464 | - | 4 | 4 | N | i21-43o55-76i117-138o150-174i | CytoplasmicMembrane | 10 | 35 | ||||||
| FDOI_ECOLI | P0AEL0 | fdoI | b3892 JW3863 | integral IM protein (SEC in IM), Formate dehydrogenase, cytochrome b556(fdo) subunit FdoI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.115 | TMH | 0 | 16.4965 | - | 4 | 4 | N | i20-43o55-73i113-133o145-172i | CytoplasmicMembrane | 10 | 16 | ||||||
| GALP_ECOLI | P0AEP1 | galP | b2943 JW2910 | integral IM protein (SEC in IM), Galactose-proton symporter GalP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.158 | TMH | 0 | 14.2152 | - | 12 | 12 | N | i15-44o56-77i84-103o109-130i142-160o172-192i251-274o290-310i322-342o348-373i385-406o418-436i | CytoplasmicMembrane | 10 | |||||||
| GLNP_ECOLI | P0AEQ6 | glnP | b0810 JW0795 | integral IM protein (SEC in IM), Glutamine transport system permease GlnP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.119 | TMH | 0 | 7.24978 | - | 3 | 5 | N | o23-42i54-78o90-113i125-144o190-209i | CytoplasmicMembrane | 10 | |||||||
| GLPF_ECOLI | P0AER0 | glpF | b3927 JW3898 | integral IM protein (SEC in IM), Glycerol uptake facilitator GlpF | Integral Inner Membrane | PMID: 11039922 PMID: 11266632 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.125 | TMH | 0 | 9.6263 | - | 6 | 6 | N | i12-34o46-79i86-108o145-166i178-202o230-251i | CytoplasmicMembrane | 10 | |||||||
| GLTJ_ECOLI | P0AER3 | gltJ | b0654 JW0649 | integral IM protein (SEC in IM), Glutamate/aspartate import permease GltJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.108 | TMH | 0 | 9.38551 | - | 5 | 5 | N | o24-50i71-88o108-127i179-199o211-233i | CytoplasmicMembrane | 10 | |||||||
| GLTK_ECOLI | P0AER5 | gltK | b0653 JW0648 | integral IM protein (SEC in IM), Glutamate/aspartate import permease GltK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.129 | TMH | 0 | 7.84867 | - | 5 | 5 | N | o20-44i65-83o95-112i153-178o198-219i | CytoplasmicMembrane | 10 | |||||||
| GLTS_ECOLI | P0AER8 | gltS gltC | gltC | b3653 JW3628 | integral IM protein (SEC in IM), Sodium/glutamate symporter GltS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 27 | 0.145 | CYT | 0 | -0.200913 | - | 9 | 11 | Y | n7-18c26/27o36-52i72-90o96-119i126-148o160-184i215-239o245-268i275-297o303-323i335-357o369-394i | CytoplasmicMembrane | 10 | ||||||
| HDED_ECOLI | P0AET5 | hdeD yhiA | yhiA | b3511 JW3479 | integral IM protein (SEC in IM), HdeD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.139 | TMH | 0 | 3.36767 | - | 6 | 6 | N | i23-42o48-69i76-97o103-124i136-155o161-187i | CytoplasmicMembrane | 10 | ||||||
| HISM_ECOLI | P0AEU3 | hisM | b2307 JW2304 | integral IM protein (SEC in IM), Histidine transport system permease HisM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.123 | TMH | 0 | 10.1822 | - | 4 | 3 | N | o20-45i57-79o200-221i | CytoplasmicMembrane | 10 | |||||||
| HYFE_ECOLI | P0AEW1 | hyfE | b2485 JW2470 | integral IM protein (SEC in IM), Hydrogenase-4 component E HyfE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 54 | 0.165 | TMH | 0 | 4.55769 | - | 7 | 7 | N | o6-24i31-54o60-80i92-114o126-143i152-171o177-196i | CytoplasmicMembrane | 10 | |||||||
| KGTP_ECOLI | P0AEX3 | kgtP witA | witA | b2587 JW2571 | integral IM protein (SEC in IM), Alpha-ketoglutarate permease KgtP | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | no | yes | N | 9 | 0.105 | TMH | 0 | 2.8422 | - | 12 | 12 | N | i21-42o62-84i96-116o122-139i160-183o195-214i244-266o278-299i311-331o337-360i372-393o405-423i | CytoplasmicMembrane | 10 | |||||
| LIVH_ECOLI | P0AEX7 | livH | b3457 JW3422 | integral IM protein (SEC in IM), High-affinity branched-chain amino acid transport system permease LivH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 45 | 0.186 | TMH | 0 | 16.6878 | - | 8 | 8 | N | o20-39i46-64o70-89i105-122o158-175i204-230o242-270i282-301o | CytoplasmicMembrane | 10 | |||||||
| MARC_ECOLI | P0AEY1 | marC ydeB ydeC | ydeB ydeC | b1529 JW1522 | integral IM protein (SEC in IM), UPF0056 MarC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 38 | 0.16 | TMH | 0 | 10.7793 | - | 5 | 5 | N | o12-32i44-62o68-89i151-172o192-214i | CytoplasmicMembrane | 10 | 5 | |||||
| MDFA_ECOLI | P0AEY8 | mdfA cmlA cmr | cmlA cmr | b0842 JW0826 | integral IM protein (SEC-YidC in IM), Multidrug transporter MdfA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 32 | 0.122 | TMH | 0 | 6.20433 | - | 12 | 12 | N | i15-33o53-72i84-103o109-130i142-164o170-188i221-246o258-275i287-308o314-335i347-367o379-399i | CytoplasmicMembrane | 10 | |||||
| MODB_ECOLI | P0AF01 | modB chlJ | chlJ | b0764 JW0747 | integral IM protein (SEC in IM), Molybdenum transport system permease ModB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 34 | 0.137 | TMH | 0 | 8.18777 | - | 5 | 5 | N | o20-37i49-70o90-115i136-158o198-220i | CytoplasmicMembrane | 10 | 20 | |||||
| MOTB_ECOLI | P0AF06 | motB | b1889 JW1878 | integral IM protein (SEC in IM), Motility B MotB | Integral Inner Membrane | MotB has one membrane-spanning alpha-helix but the majority of the molecule is in the periplasmic space with a peptidoglycan-binding domain near its C-terminus PMID: 2447650 | PMID: 12730325 PMID: 19364805 PMID: 23193105 PMID: 2447650 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 32 | 0.155 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o28-47i | CytoplasmicMembrane | 7 | 33 | |||||
| MURJ_ECOLI | P0AF16 | murJ mviN yceN | mviN yceN | b1069 JW1056 | integral IM protein (SEC in IM), Lipid II flippase MurJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.165 | SpI | 23 | 0.241812 | - | 13 | 13 | N | o27-45i82-110o130-154i161-182o188-205i236-262o274-292i313-334o354-371i383-402o408-429i441-466o478-501i | CytoplasmicMembrane | 10 | ||||||
| NARV_ECOLI | P0AF32 | narV | b1465 JW1460 | integral IM protein (SEC in IM), Respiratory nitrate reductase 2 gamma chain NarV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.114 | TMH | 0 | 10.9916 | - | 5 | 5 | N | o12-29i50-69o89-111i132-151o180-199i | CytoplasmicMembrane | 10 | |||||||
| YIIR_ECOLI | P0AF34 | yiiR | b3921 JW3892 | integral IM protein (SEC in IM), YiiR | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.144 | TMH | 0 | 5.06913 | - | 4 | 4 | N | i20-38o44-63i75-93o99-121i | CytoplasmicMembrane | 10 | 49 | |||||||||
| YIJD_ECOLI | P0AF40 | yijD | b3964 JW3936 | integral IM protein (SEC in IM), YijD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.345 | TMH | 0 | 8.09717 | - | 4 | 3 | Y | n10-21c26/27o36-51i63-83o89-108i | CytoplasmicMembrane | 10 | 21 | ||||||
| YJBB_ECOLI | P0AF43 | yjbB | b4020 JW3980 | integral IM protein (SEC in IM), YjbB | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.13 | TMH | 0 | 1.33234 | - | 8 | 8 | Y | n2-13c17/18o45-64i76-98o104-121i133-151o171-194i206-226o238-262i274-294o | CytoplasmicMembrane | 10 | 4 | ||||||||
| GHXP_ECOLI | P0AF52 | ghxP yjcD | yjcD | b4064 JW4025 | integral IM protein (SEC in IM), Guanine/hypoxanthine permease GhxP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 59 | 0.114 | CYT | 0 | -0.200913 | - | 13 | 13 | N | i29-49o55-74i81-101o107-129i141-165o171-195i202-220o256-280i301-321o333-350i357-378o390-416i428-448o | CytoplasmicMembrane | 10 | ||||||
| YJCH_ECOLI | P0AF54 | yjcH | b4068 JW4029 | integral IM protein (SEC in IM), YjcH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.119 | TMH | 0 | 4.65174 | - | 2 | 2 | N | i25-51o63-84i | CytoplasmicMembrane | 10 | 54 | ||||||
| YJET_ECOLI | P0AF73 | yjeT | b4176 JW4134 | integral IM protein (SEC in IM), YjeT | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.108 | TMH | 0 | 4.78812 | - | 2 | 1 | Y | n3-13c17/18o41-60i | CytoplasmicMembrane | 9 | 19 | ||||||||
| YJFL_ECOLI | P0AF80 | yjfL | b4184 JW4142 | integral IM protein (SEC in IM), UPF0719 YjfL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.123 | TMH | 0 | 8.65955 | - | 4 | 4 | N | o6-28i49-69o75-97i109-128o | CytoplasmicMembrane | 10 | 19 | ||||||
| LPTF_ECOLI | P0AF98 | lptF yjgP | yjgP | b4261 JW4218 | integral IM protein (SEC in IM), polysaccharide export system permease LptF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.124 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i16-39o59-76i97-119o268-289i296-316o328-348i | CytoplasmicMembrane | 10 | 13 | |||||
| NARX_ECOLI | P0AFA2 | narX narR | narR | b1222 JW1213 | integral IM protein (SEC in IM), Nitrate/nitrite sensor NarX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.224 | SpI | 33 | 4.68578 | - | 2 | 2 | N | i12-36o154-174i | CytoplasmicMembrane | 10 | 44 | |||||
| NFRB_ECOLI | P0AFA5 | nfrB | b0569 JW0558 | integral IM protein (SEC in IM), Bacteriophage adsorption B NfrB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 20 | 0.134 | CYT | 0 | -0.200913 | - | 4 | 4 | N | o12-42i365-384o390-410i422-443o | CytoplasmicMembrane | 10 | 7 | ||||||
| NHAB_ECOLI | P0AFA7 | nhaB | b1186 JW1175 | integral IM protein (SEC in IM), Na(+)/H(+) antiporter NhaB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.149 | TMH | 0 | 10.0118 | - | 12 | 12 | N | o20-47i59-77o89-108i120-141o147-165i202-219o239-260i299-331o351-368i389-413o453-471i478-498o | CytoplasmicMembrane | 10 | |||||||
| NIKC_ECOLI | P0AFA9 | nikC | b3478 JW3443 | integral IM protein (SEC in IM), Nickel transport system permease NikC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 25 | 0.156 | TMH | 0 | 10.244 | - | 6 | 6 | N | i12-32o75-100i121-148o177-196i203-222o242-260i | CytoplasmicMembrane | 10 | |||||||
| NUOA_ECOLI | P0AFC3 | nuoA | b2288 JW2283 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit A NuoA | Integral Inner Membrane | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 15919996 PMID: 21541338 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.182 | TMH | 0 | 12.5237 | - | 3 | 3 | N | o12-37i68-88o100-122i | CytoplasmicMembrane | 10 | 48 | |||||
| NUOH_ECOLI | P0AFD4 | nuoH | b2282 JW2277 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit H NuoH | Integral Inner Membrane | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 33 | 0.139 | TMH | 0 | 7.32865 | - | 8 | 9 | N | i12-32o52-69i81-100o112-133i154-174o186-207i234-257o269-289i301-322o | CytoplasmicMembrane | 10 | |||||||
| NUOJ_ECOLI | P0AFE0 | nuoJ | b2280 JW2275 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit J NuoJ | Integral Inner Membrane | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.504 | TMH | 0 | 10.2272 | - | 5 | 4 | Y | n3-14c18/19o28-49i56-74o94-112i133-158o | CytoplasmicMembrane | 10 | 82 | ||||||
| NUOK_ECOLI | P0AFE4 | nuoK | b2279 JW2274 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit K NuoK | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.166 | TMH | 0 | 8.16488 | - | 3 | 3 | N | o6-24i29-54o60-81i | CytoplasmicMembrane | 10 | ||||||
| NUOM_ECOLI | P0AFE8 | nuoM | b2277 JW2272 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit M NuoM | Integral Inner Membrane | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 59 | 0.116 | TMH | 0 | 6.38779 | - | 14 | 14 | N | o6-23i30-48o77-103i115-134o140-159i180-199o219-244i256-274o286-307i314-333o345-363i383-405o417-440i461-481o | CytoplasmicMembrane | 10 | |||||||
| NUON_ECOLI | P0AFF0 | nuoN | b2276 JW2271 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit N NuoN | Integral Inner Membrane | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 61 | 0.262 | TMH | 0 | 9.81822 | - | 14 | 14 | N | o6-28i35-55o75-93i105-122o128-147i159-181o201-226i238-259o271-290i297-316o328-351i371-394o406-426i447-470o | CytoplasmicMembrane | 10 | |||||||
| NUPC_ECOLI | P0AFF2 | nupC cru | cru | b2393 JW2389 | integral IM protein (SEC in IM), Nucleoside permease NupC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 27 | 0.126 | TMH | 0 | 0.463943 | - | 8 | 9 | N | o6-23i30-48o87-108i167-187o193-212i242-271o277-298i341-361o381-399i | CytoplasmicMembrane | 10 | ||||||
| NUPG_ECOLI | P0AFF4 | nupG | b2964 JW2932 | integral IM protein (SEC in IM), Nucleoside permease NupG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.127 | TMH | 0 | 10.0497 | - | 12 | 12 | N | i12-31o37-58i70-89o95-116i137-155o161-179i211-235o255-275i282-300o306-327i348-369o381-402i | CytoplasmicMembrane | 10 | |||||||
| OPPB_ECOLI | P0AFH2 | oppB | b1244 JW1236 | integral IM protein (SEC in IM), Oligopeptide transport system permease OppB | Integral Inner Membrane | Opp-LacZ hybrid proteins were used to show that OppB, OppC and OppD are membrane-associated proteins. PMID: 2821267 | PMID: 15919996 PMID: 2821267 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 48 | 0.124 | TMH | 0 | 3.13181 | - | 6 | 6 | N | i12-30o100-121i133-161o173-192i228-254o274-300i | CytoplasmicMembrane | 10 | ||||||
| OPPC_ECOLI | P0AFH6 | oppC | b1245 JW1237 | integral IM protein (SEC in IM), Oligopeptide transport system permease OppC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 64 | 0.213 | TMH | 0 | 0.755301 | - | 6 | 6 | N | i40-64o103-128i140-158o164-183i218-247o267-290i | CytoplasmicMembrane | 10 | |||||||
| PERM_ECOLI | P0AFI9 | perM yfgO | yfgO | b2493 JW2478 | integral IM protein (SEC in IM), Putative permease PerM | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.135 | TMH | 0 | 20.7793 | - | 7 | 7 | N | o20-51i72-93o151-177i217-236o242-270i282-301o307-332i | CytoplasmicMembrane | 10 | 26 | |||||||
| PITA_ECOLI | P0AFJ7 | pitA pit | pit | b3493 JW3460 | integral IM protein (SEC in IM), Low-affinity inorganic phosphate transporter 1 PitA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 39 | 0.147 | TMH | 0 | 8.59981 | - | 10 | 9 | N | o12-32i52-76o96-116i123-143o155-177i208-227o233-255i379-402o474-494i | CytoplasmicMembrane | 10 | ||||||
| PNUC_ECOLI | P0AFK2 | pnuC | b0751 JW0734 | integral IM protein (SEC in IM), Nicotinamide riboside transporter PnuC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.115 | TMH | 0 | 3.57186 | - | 6 | 7 | N | o22-40i47-65o71-88i109-139o159-178i185-205o211-226i | CytoplasmicMembrane | 10 | |||||||
| POTB_ECOLI | P0AFK4 | potB | b1125 JW1111 | integral IM protein (SEC in IM), Spermidine/putrescine transport system permease PotB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.107 | TMH | 0 | 5.71787 | - | 6 | 7 | N | o6-26i54-78o90-108i120-138o144-163i184-214o242-262i | CytoplasmicMembrane | 10 | |||||||
| POTC_ECOLI | P0AFK6 | potC | b1124 JW1110 | integral IM protein (SEC in IM), Spermidine/putrescine transport system permease PotC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 60 | 0.118 | TMH | 0 | 10.8409 | - | 6 | 6 | N | i12-30o64-86i98-122o128-151i172-195o230-252i | CytoplasmicMembrane | 10 | |||||||
| POTI_ECOLI | P0AFL1 | potI | b0857 JW0841 | integral IM protein (SEC in IM), Putrescine transport system permease PotI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.124 | TMH | 0 | 14.5424 | - | 6 | 7 | N | i12-35o60-90i102-129o141-163i184-206o212-232i244-264o | CytoplasmicMembrane | 10 | |||||||
| PQIA_ECOLI | P0AFL9 | pqiA pqi5A | pqi5A | b0950 JW0933 | integral IM protein (SEC in IM), Intertransport PqiA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 33 | 0.119 | CYT | 0 | -0.200913 | - | 8 | 8 | N | i53-76o96-122i142-160o166-185i257-277o304-329i350-371o377-400i | CytoplasmicMembrane | 10 | ||||||
| PSPB_ECOLI | P0AFM9 | pspB | b1305 JW1298 | integral IM protein (SEC in IM), Phage shock B PspB | Integral Inner Membrane | Defects in yidC and sec secretion induce psp operon. PMID: 14594846 | PMID: 14594846 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Single-pass membrane protein | Membrane anchored | SRP | SEC | Prophage Transposase (by homology to BL21) | no | yes | N | 30 | 0.112 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-24i | CytoplasmicMembrane | 10 | 62 | ||||
| PSPC_ECOLI | P0AFN2 | pspC | b1306 JW1299 | integral IM protein (SEC in IM), Phage shock C PspC | Integral Inner Membrane | Defects in yidC and sec secretion induce psp operon. PMID: 14594846 | PMID: 14594846 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | Prophage Transposase | yes | no | N | 25 | 0.142 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o39-64i | CytoplasmicMembrane | 9 | 29 | ||||
| YADH_ECOLI | P0AFN6 | yadH | b0128 JW0124 | integral IM protein (SEC in IM), transport permease YadH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.101 | TMH | 0 | 8.75539 | - | 6 | 7 | Y | n4-9c14/15o24-46i58-84o104-132i139-164o170-191i203-221o227-248i | CytoplasmicMembrane | 10 | 4 | ||||||
| YADS_ECOLI | P0AFP0 | yadS | b0157 JW0153 | integral IM protein (SEC in IM), UPF0126 YadS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.24 | TMH | 0 | 2.68818 | - | 7 | 7 | N | o6-23i30-50o62-79i91-110o116-137i149-168o174-190i | CytoplasmicMembrane | 10 | |||||||
| YBHR_ECOLI | P0AFP9 | ybhR | b0792 JW5803 | integral IM protein (SEC in IM), Probable multidrug ABC transporter permease YbhR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.153 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i21-41o173-197i218-243o255-277i284-302o345-363i | CytoplasmicMembrane | 10 | |||||||
| YBHS_ECOLI | P0AFQ2 | ybhS | b0793 JW0777 | integral IM protein (SEC in IM), Probable multidrug ABC transporter permease YbhS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 67 | 0.102 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i29-47o182-205i232-255o261-283i295-314o346-370i | CytoplasmicMembrane | 10 | 7 | ||||||
| DAUA_ECOLI | P0AFR2 | dauA ychM | ychM | b1206 JW5189 | integral IM protein (SEC in IM), C4-dicarboxylic acid transporter DauA | Integral Inner Membrane | PMID: 15919996 PMID: 23278959 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 69 | 0.11 | CYT | 0 | -0.200913 | - | 11 | 9 | N | o33-53i60-80o100-118i130-152o172-198i210-231o278-300i358-388o408-438i | CytoplasmicMembrane | 10 | ||||||
| YCJO_ECOLI | P0AFR7 | ycjO | b1311 JW1304 | integral IM protein (SEC in IM), ABC transporter permease YcjO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.147 | TMH | 0 | 12.2234 | - | 6 | 5 | Y | n14-25c30/31o77-98i110-130o163-189i210-233o265-283i | CytoplasmicMembrane | 10 | |||||||
| YDCV_ECOLI | P0AFR9 | ydcV | b1443 JW1438 | integral IM protein (SEC in IM), ABC transporter permease YdcV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.134 | TMH | 0 | 8.81303 | - | 6 | 6 | N | i12-33o71-91i103-127o133-153i189-212o232-256i | CytoplasmicMembrane | 10 | |||||||
| LSRD_ECOLI | P0AFS1 | lsrD ydeZ | ydeZ | b1515 JW1508 | integral IM protein (SEC in IM), Autoinducer 2 import system permease LsrD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.162 | TMH | 0 | 9.62635 | - | 9 | 9 | Y | n9-17c23/24o33-56i63-82o88-110i117-140o160-181i212-234o240-260i267-286o292-310i | CytoplasmicMembrane | 10 | ||||||
| TQSA_ECOLI | P0AFS5 | tqsA ydgG | ydgG | b1601 JW1593 | integral IM protein (SEC in IM), AI-2 transport TqsA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.372 | TMH | 0 | 8.36419 | - | 8 | 8 | N | i12-31o37-55i62-83o144-165i197-218o224-246i258-279o299-325i | CytoplasmicMembrane | 10 | ||||||
| YDIK_ECOLI | P0AFS7 | ydiK | b1688 JW1678 | integral IM protein (SEC in IM), Putative transport YdiK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.172 | TMH | 0 | 13.7653 | - | 9 | 9 | N | i12-31o37-53i65-86o160-179i191-208o214-235i247-271o277-295i307-334o | CytoplasmicMembrane | 10 | |||||||
| MEPM_ECOLI | P0AFS9 | mepM yebA | yebA | b1856 JW5304 | integral IM protein (SEC in IM), Murein DD-endopeptidase MepM MepM | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 12 | 0.112 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i21-39o | Unknown | 2 | 33 | |||||||
| YECS_ECOLI | P0AFT2 | yecS | b1918 JW1903 | integral IM protein (SEC in IM), L-cystine transport system permease YecS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 70 | 0.103 | TMH | 0 | 8.62641 | - | 3 | 3 | N | o21-45i57-78o186-206i | CytoplasmicMembrane | 10 | 4 | ||||||
| YEJB_ECOLI | P0AFU0 | yejB | b2178 JW2166 | integral IM protein (SEC in IM), ABC transporter permease YejB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.157 | TMH | 0 | 4.74055 | - | 6 | 6 | N | i9-30o135-156i168-194o224-247i282-309o329-355i | CytoplasmicMembrane | 10 | |||||||
| YFBS_ECOLI | P0AFU2 | yfbS | b2292 JW2289 | integral IM protein (SEC in IM), transporter YfbS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.196 | TMH | 0 | 7.38351 | - | 10 | 10 | N | i5-22o28-45i57-83o95-124i136-155o175-195i470-493o513-538i550-568o588-608i | CytoplasmicMembrane | 10 | |||||||
| YIBH_ECOLI | P0AFV0 | yibH | b3597 JW3571 | integral IM protein (SEC in IM), YibH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Membrane anchored | SRP | SEC | yes | yes | N | 53 | 0.113 | TMH | 0 | 2.25888 | - | 2 | 1 | Y | n3-13c18/19o28-49i | CytoplasmicMembrane | 10 | 23 | ||||||
| YHID_ECOLI | P0AFV2 | yhiD yhhE | yhhE | b3508 JW5670 | integral IM protein (SEC in IM), Putative magnesium transporter YhiD | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 55 | 0.254 | CYT | 0 | -0.200913 | - | 5 | 5 | N | o6-22i34-54o69-87i92-112o118-138i | CytoplasmicMembrane | 10 | 28 | |||||||
| RSEA_ECOLI | P0AFX7 | rseA mclA yfiJ | mclA yfiJ | b2572 JW2556 | integral IM protein (SEC in IM), Anti-sigma-E factor RseA | Integral Inner Membrane | Responce to stress complex RpoE-RseA-RseB. Overproduction of N-terminal domain of RseA alone was shown to inhibit ??E activity. RseC which is an inner membrane protein, positively modulates ??E activity. The periplasmic domain of RseA interacts with RseB while its cytoplasmic domain interacts with RpoE, thereby sequestering RpoE away from the transcription complex. Proteolysis of transmembrane and cytoplasmic portions of RseA by DegS frees the sigma(E) transcription factor. RseB protein, a known negative regulator, inhibits proteolysis by DegS in vitro by binding tightly to the periplasmic domain of RseA. PMID: 17360428 The N-terminal domain of RseA sequesters ??E in the cytoplasmic membrane, preventing its association with core RNA polymerase. The C-terminal domain of RseA interacts with RseB, a periplasmic protein. PMID: 11777003 Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA reveals that RseA functions by sterically occluding the two primary binding determinants on sigma(E) for core RNA polymerase. PMID: 12718891 | PMID: 11777003 PMID: 12183369 PMID: 12718891 PMID: 17360428 PMID: 9159522 PMID: 9159523 | Integral Inner Membrane | B | - | IM (predicted-detected) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 62 | 0.226 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 59 | |||||
| SANA_ECOLI | P0AFY2 | sanA yeiF | yeiF | b2144 JW2132 | integral IM protein (SEC in IM), SanA | Integral Inner Membrane | Related to vancomycin resistance and when overexpressed, is able to complement the permeability defects of a vancomycin-susceptible mutant. | PMID: 8550448 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane; Single-pass membrane protein | Periplasmic | SRP | SEC | yes | yes | N | 23 | 0.14 | TMH | 0 | 6.95693 | - | 1 | 0 | Y | n5-18c22/23o | CytoplasmicMembrane | 10 | 10 | ||||
| SBMA_ECOLI | P0AFY6 | sbmA | b0377 JW0368 | integral IM protein (SEC in IM), Peptide antibiotic transporter SbmA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.182 | TMH | 0 | 18.7145 | - | 8 | 8 | N | i12-30o58-78i85-112o140-164i206-227o239-263i309-326o332-353i | CytoplasmicMembrane | 10 | |||||||
| TRKH_ECOLI | P0AFZ7 | trkH | b3849 JW5576 | integral IM protein (SEC in IM), Trk system potassium uptake TrkH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | yes | N | 41 | 0.127 | TMH | 0 | 6.71344 | - | 10 | 11 | N | i12-32o38-57i69-90o136-163i184-204o241-262i274-294o331-363i396-417o423-444i456-481o | CytoplasmicMembrane | 10 | ||||||
| WZZE_ECOLI | P0AG00 | wzzE wzz yifC | wzz yifC | b3785 JW5601 | integral IM protein (SEC in IM), ECA polysaccharide chain length modulation protein WzzE | Integral Inner Membrane | PMID: 15919996 PMID: 16199561 PMID: 16816184 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 47 | 0.253 | TMH | 0 | 8.70367 | - | 2 | 2 | N | o31-50i323-342o | CytoplasmicMembrane | 10 | 19 | |||||
| SOHB_ECOLI | P0AG14 | sohB | b1272 JW1264 | integral IM protein (SEC in IM), Probable protease SohB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Single-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.141 | CYT | 0 | -0.200913 | - | 2 | 1 | N | o12-32i | CytoplasmicMembrane | 10 | 8 | ||||||
| YIBN_ECOLI | P0AG27 | yibN | b3611 JW3586 | integral IM protein (SEC in IM), YibN | Integral Inner Membrane | PMID: 15919657 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Membrane anchored | SRP | SEC | yes | yes | N | 36 | 0.109 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o12-30i | Unknown | 2 | 48 | |||||||
| RHTB_ECOLI | P0AG34 | rhtB yigK | yigK | b3824 JW5585 | integral IM protein (SEC in IM), Homoserine/homoserine lactone efflux protein RhtB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein (Experimental) | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | no | yes | N | 25 | 0.247 | TMH | 0 | 11.1132 | - | 5 | 4 | Y | n7-18c23/24o39-65i116-138o144-168i188-205o | CytoplasmicMembrane | 10 | |||||
| RHTC_ECOLI | P0AG38 | rhtC yigJ | yigJ | b3823 JW5586 | integral IM protein (SEC in IM), Threonine efflux protein RhtC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | yes | N | 25 | 0.144 | TMH | 0 | 8.74493 | - | 6 | 6 | N | o6-26i38-63o69-87i119-140o152-174i186-204o | CytoplasmicMembrane | 10 | |||||
| RMUC_ECOLI | P0AG71 | rmuC yigN | yigN | b3832 JW3809 | integral IM protein (SEC in IM), DNA recombination RmuC | Integral Inner Membrane | Based on the fact that RmuC is a DNA recombination enzyme we conluded that its N-terminus lays in the periplasm. | PMID: 16011798 | Integral Inner Membrane | B | Bin | out/in | N/A | Cytoplasmic | SRP | SEC | yes | yes | N | 29 | 0.536 | SpI | 28 | 1.08238 | - | 1 | 1 | N | o6-25i | Unknown | 2 | 15 | |||||
| SECD_ECOLI | P0AG90 | secD | b0408 JW0398 | integral IM protein (SEC in IM), translocase subunit SecD | Integral Inner Membrane | PMID: 15919657 PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.158 | TMH | 0 | 1.57163 | - | 6 | 6 | N | i7-25o453-472i477-497o503-524i545-571o577-605i | CytoplasmicMembrane | 10 | 36 | ||||||
| SECF_ECOLI | P0AG93 | secF | b0409 JW0399 | integral IM protein (SEC in IM), translocase subunit SecF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 3 | 0.112 | TMH | 0 | 2.24012 | - | 6 | 6 | N | i24-43o142-163i170-191o197-217i248-266o272-297i | CytoplasmicMembrane | 10 | |||||||
| SECE_ECOLI | P0AG96 | secE prlG | prlG | b3981 JW3944 | integral IM protein (SEC in IM), translocase subunit SecE | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 48 | 0.137 | TMH | 0 | 7.80526 | - | 3 | 3 | N | o16-36i43-61o95-119i | CytoplasmicMembrane | 10 | 7 | ||||
| SECG_ECOLI | P0AG99 | secG | b3175 JW3142 | integral IM protein (SEC in IM), Protein-export SecG | Integral Inner Membrane | PMID: 15919657 PMID: 15919996 | Integral Inner Membrane | B | Binout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.153 | TMH | 0 | 11.5638 | - | 2 | 1 | Y | n4-22c27/28o51-70i | CytoplasmicMembrane | 10 | 49 | ||||||
| SECY_ECOLI | P0AGA2 | secY prlA | prlA | b3300 JW3262 | integral IM protein (SEC in IM), translocase subunit SecY | Integral Inner Membrane | PMID: 15919996 PMID: 3004955 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 47 | 0.104 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i23-44o75-98i119-139o154-174i186-203o215-237i274-296o316-337i373-391o397-418i | CytoplasmicMembrane | 10 | ||||||
| UHPT_ECOLI | P0AGC0 | uhpT | b3666 JW3641 | integral IM protein (SEC in IM), Hexose-6-phosphate:phosphate antiporter UhpT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 53 | 0.105 | TMH | 0 | 0.582302 | - | 12 | 12 | N | i28-45o65-85i97-117o123-148i160-183o189-210i260-278o298-318i327-345o351-380i392-411o423-446i | CytoplasmicMembrane | 10 | |||||||
| SMP_ECOLI | P0AGC7 | ytjB smp | smp | b4387 JW4350 | integral IM protein (SEC in IM), YtjB | Integral Inner Membrane | Has an aminoterminal stop transfer or signal sequence hydrophobic region and a second hydrophobic region near the C-terminus that may function as a stop transfer sequence; The protein was shown to fractionate with the bacterial membrane. No processing of t | PMID: 2684780 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | no | no | N | 30 | 0.128 | SpI | 30 | 7.66045 | - | 1 | 1 | Y | n13-24c29/30o164-184i | CytoplasmicMembrane | 10 | 63 | |||
| SSTT_ECOLI | P0AGE4 | sstT ygjU | ygjU | b3089 JW3060 | integral IM protein (SEC in IM), Serine/threonine transporter SstT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.148 | TMH | 0 | 7.50816 | - | 8 | 8 | N | i18-36o42-72i84-106o149-166i187-209o215-240i290-315o327-352i | CytoplasmicMembrane | 10 | 15 | |||||
| XYLE_ECOLI | P0AGF4 | xylE | b4031 JW3991 | integral IM protein (SEC in IM), D-xylose-proton symporter XylE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.155 | TMH | 0 | 6.47202 | - | 12 | 11 | Y | n13-24c32/33o56-78i90-109o129-151i163-186o198-220i270-293o313-334i346-364o370-395i407-426o446-463i | CytoplasmicMembrane | 10 | |||||||
| YHHJ_ECOLI | P0AGH1 | yhhJ | b3485 JW5677 | integral IM protein (SEC in IM), transport permease YhhJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.231 | SpI | 40 | 1.57995 | - | 5 | 6 | N | i174-200o220-244i256-281o287-306i318-337o343-364i | CytoplasmicMembrane | 10 | 6 | ||||||
| SAPB_ECOLI | P0AGH3 | sapB | b1293 JW1286 | integral IM protein (SEC in IM), Putrescine export system permease SapB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.197 | TMH | 0 | 16.0324 | - | 5 | 6 | N | i9-29o82-101i113-141o175-193i245-263o283-305i | CytoplasmicMembrane | 10 | 9 | ||||||
| SAPC_ECOLI | P0AGH5 | sapC | b1292 JW1285 | integral IM protein (SEC in IM), Putrescine export system permease SapC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.132 | TMH | 0 | 5.59827 | - | 5 | 6 | N | i31-54o99-123i144-169o189-208i220-241o261-283i | CytoplasmicMembrane | 10 | 10 | ||||||
| PSTC_ECOLI | P0AGH8 | pstC phoW | phoW | b3727 JW3705 | integral IM protein (SEC in IM), Phosphate transport system permease PstC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 3 | 0.109 | TMH | 0 | 4.7509 | - | 6 | 6 | N | i21-43o75-100i112-143o163-186i227-249o282-304i | CytoplasmicMembrane | 10 | ||||||
| RBSC_ECOLI | P0AGI1 | rbsC | b3750 JW3729 | integral IM protein (SEC in IM), Ribose import permease RbsC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 58 | 0.121 | TMH | 0 | 6.39117 | - | 8 | 10 | N | i23-43o49-68i75-93o99-119i126-144o170-190i221-240o252-270i275-292o298-316i | CytoplasmicMembrane | 10 | 18 | ||||||
| XYLH_ECOLI | P0AGI4 | xylH | b3568 JW3540 | integral IM protein (SEC in IM), Xylose transport system permease XylH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.13 | TMH | 0 | 4.89182 | - | 10 | 11 | N | i25-45o65-83i90-107o113-132i139-156o176-196i217-235o241-259i290-306o326-357i369-385o | CytoplasmicMembrane | 10 | |||||||
| UBIA_ECOLI | P0AGK1 | ubiA cyr | cyr | b4040 JW4000 | integral IM protein (SEC in IM), 4-hydroxybenzoate octaprenyltransferase UbiA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 36 | 0.118 | TMH | 0 | 6.00125 | - | 7 | 7 | N | i23-40o46-70i99-132o152-182i210-229o235-252i273-289o | CytoplasmicMembrane | 10 | ||||||
| YHHT_ECOLI | P0AGM0 | yhhT | b3474 JW5680 | integral IM protein (SEC in IM), Putative transport YhhT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.162 | TMH | 0 | 5.38885 | - | 8 | 8 | N | i12-31o37-55i62-87o133-163i197-215o221-246i253-275o295-315i | CytoplasmicMembrane | 10 | 4 | ||||||
| YICG_ECOLI | P0AGM2 | yicG | b3646 JW3621 | integral IM protein (SEC in IM), UPF0126 YicG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.368 | CYT | 0 | -0.200913 | - | 7 | 7 | N | o6-23i30-52o64-82i89-109o115-136i148-167o173-191i | CytoplasmicMembrane | 10 | |||||||
| URAA_ECOLI | P0AGM7 | uraA | b2497 JW2482 | integral IM protein (SEC in IM), Uracil permease UraA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.107 | TMH | 0 | 3.93213 | - | 12 | 13 | N | i20-38o44-60i67-83o89-108i120-147o159-176i183-202o225-250i262-281o301-319i331-354o366-384i391-409o | CytoplasmicMembrane | 10 | |||||||
| XANP_ECOLI | P0AGM9 | xanP yicE | yicE | b3654 JW3629 | integral IM protein (SEC in IM), Xanthine permease XanP | Integral Inner Membrane | PMID: 15919996 PMID: 16096267 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 66 | 0.123 | CYT | 0 | -0.200913 | - | 11 | 11 | N | o36-58i70-89o128-146i158-181o193-212i219-240o260-280i350-372o378-396i408-427o439-458i | CytoplasmicMembrane | 10 | 9 | |||||
| PROP_ECOLI | P0C0L7 | proP | b4111 JW4072 | integral IM protein (SEC in IM), Proline/betaine transporter ProP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.105 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i41-59o65-86i98-116o122-146i167-186o198-217i257-278o298-318i327-346o352-376i388-411o417-438i | CytoplasmicMembrane | 10 | |||||||
| MSCS_ECOLI | P0C0S1 | mscS yggB | yggB | b2924 JW2891 | integral IM protein (SEC in IM), Small-conductance mechanosensitive channel MscS | Integral Inner Membrane | PMID: 10202137 PMID: 11266632 PMID: 12015316 PMID: 12446901 PMID: 12767977 PMID: 15919657 PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 52 | 0.15 | TMH | 0 | -0.184901 | - | 3 | 3 | N | o24-45i65-85o97-125i | CytoplasmicMembrane | 10 | 42 | |||||
| EPTC_ECOLI | P0CB39 | eptC cptA yijP | cptA yijP | b3955 JW3927 | integral IM protein (SEC in IM), Phosphoethanolamine transferase EptC | Integral Inner Membrane | PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 9 | 0.182 | TMH | 0 | 12.4414 | - | 5 | 5 | N | i20-39o45-63i70-91o120-139i151-169o | CytoplasmicMembrane | 10 | 26 | |||||
| YMIA_ECOLI | P0CB62 | ymiA | b4522 JW1267.1 | integral IM protein (SEC in IM), YmiA | Integral Inner Membrane | Small membrane protein detected experimentally | PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | N/A | Membrane | - | SEC | no | yes | N | 35 | 0.102 | TMH | 0 | 1.19842 | - | 1 | 1 | N | i20-41o | CytoplasmicMembrane | 9 | |||||||
| UIDB_ECOLI | P0CE44 | uidB gusB uidP | gusB uidP | b1616 JW1608 | integral IM protein (SEC in IM), Glucuronide carrier homolog UidB | Integral Inner Membrane | PMID: 15774881 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 61 | 0.197 | TMH | 0 | 5.96454 | - | 12 | 12 | N | i12-35o41-60i81-101o113-136i148-170o182-201i230-257o263-284i296-316o322-343i376-393o405-427i | CytoplasmicMembrane | 10 | ||||||
| RCSC_ECOLI | P0DMC5 | rcsC | b2218 JW5917/JW5920 | integral IM protein (SEC in IM), Sensor histidine kinase RcsC | Integral Inner Membrane | Fusions of rcsC to phoA that resulted in PhoA+ strains demonstrated that RcsC is a transmembrane protein with a periplasmic N-terminal domain and cytoplasmic C-terminal domain. | PMID: 15919996 PMID: 2404948 | Integral Inner Membrane | B | Binout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.159 | TMH | 0 | 3.16217 | - | 2 | 1 | Y | n20-31c40/41o314-334i | CytoplasmicMembrane | 10 | ||||||
| PHNE1_ECOLI | P0DP69 | phnE1 | b4104 JW4065 | integral IM protein (SEC in IM), Putative cryptic phosphonate transport system permease PhnE1 | Integral Inner Membrane | Integral Inner Membrane | B | N/A | Cell inner membrane | - | SEC | pseudogene (Uniprot) | N | 0.119 | CYT | 0 | 0.401335 | - | 3 | 3 | Y | i30-50o92-116i137-157o | Unknown | ||||||||||||||
| PHNE2_ECOLI | P0DP70 | phnE phnE2 | phnE2 | b4104 JW4065 b4103 | integral IM protein (SEC in IM), Putative cryptic phosphonate transport system permease PhnE2 | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006), pseudogene (Uniprot) | no | yes | N | 36 | 0.143 | TMH | 0 | 8.60214 | - | 6 | 6 | N | i12-33o75-99i120-143o179-197i206-224o230-250i | CytoplasmicMembrane | 10 | 7 | ||||
| LDRA_ECOLI | P0DPD0 | ldrA | b4419 JW5957 | integral IM protein (SEC in IM), Small toxic polypeptide LdrA | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 21 | 0.125 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-31i | CytoplasmicMembrane | 9 | ||||||
| LDRC_ECOLI | P0DPD1 | ldrC | b4423 JW5959 | integral IM protein (SEC in IM), Small toxic polypeptide LdrC | Integral Inner Membrane | Integral Inner Membrane | B | N/A | Cell inner membrane | - | SEC | N | 0.125 | CYT | 0 | -0.200913 | - | 1 | 1 | Y | o6-31i | Unknown | |||||||||||||||
| NARK_ECOLI | P10903 | narK | b1223 JW1214 | integral IM protein (SEC in IM), Nitrate/nitrite transporter NarK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 60 | 0.17 | TMH | 0 | 0.305282 | - | 12 | 12 | N | i38-62o74-92i104-124o130-158i178-197o217-234i255-278o290-308i320-339o351-377i404-425o437-457i | CytoplasmicMembrane | 10 | |||||||
| UGPA_ECOLI | P10905 | ugpA | b3452 JW3417 | integral IM protein (SEC in IM), sn-glycerol-3-phosphate transport system permease UgpA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.107 | TMH | 0 | 13.7961 | - | 6 | 6 | N | i12-31o78-100i112-130o157-181i206-228o267-288i | CytoplasmicMembrane | 10 | |||||||
| UGPE_ECOLI | P10906 | ugpE | b3451 JW3416 | integral IM protein (SEC in IM), sn-glycerol-3-phosphate transport system permease UgpE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.2 | TMH | 0 | 9.6685 | - | 6 | 7 | N | i7-31o81-105i112-133o145-166i187-210o216-238i250-272o | CytoplasmicMembrane | 10 | 28 | ||||||
| YIAB_ECOLI | P11286 | yiaB | b3563 JW5654 | integral IM protein (SEC in IM), YiaB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 50 | 0.132 | TMH | 0 | 7.23112 | - | 4 | 4 | N | i7-26o32-50i62-87o93-110i | CytoplasmicMembrane | 10 | 38 | ||||||
| NARI_ECOLI | P11350 | narI chlI | chlI | b1227 JW1218 | integral IM protein (SEC in IM), Respiratory nitrate reductase 1 gamma chain NarI | Integral Inner Membrane | Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (nitrate reductase A; NarGHI) PMID: 12910261. Part of the nitrate reductase A (NarGHI) of Escherichia coli which is membrane anchored through the NarI subunit. NarH is the electron transfer subunit. PMID: 12910261 In vivo associations of Escherichia coli NarJ with a peptide of the first 50 residues of nitrate reductase catalytic subunit NarG. PMID: 19295650 When E. coli is grown anaerobically in the presence of high levels of nitrate, the respiratory chain that is formed is terminated by NarGHI otherwise known as the quinol nitrate oxidoreductase. PMID: 2674654 The heterotrimeric NarGHI has an ?????? structure encoded by narGHI respectively. The ?? and ?? subunits can be purified as a soluble NarGH dimer in the cytoplasm showing that these 2 subunits associate to form a stable subcomplex before association with the membrane ?? subunit. PMID: 3371362 PMID: 3053688 | PMID: 11266632 PMID: 12910261 PMID: 15919996 PMID: 19295650 PMID: 2674654 PMID: 3053688 PMID: 3371362 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 19 | 0.113 | TMH | 0 | 11.8819 | - | 5 | 5 | N | o6-26i47-69o89-109i129-148o179-198i | CytoplasmicMembrane | 10 | |||||
| FUCP_ECOLI | P11551 | fucP | b2801 JW2772 | integral IM protein (SEC in IM), L-fucose-proton symporter FucP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 42 | 0.298 | TMH | 0 | 0.0692344 | - | 12 | 12 | N | i21-41o61-85i92-111o117-134i155-177o210-228i262-282o294-315i327-345o351-373i385-405o411-431i | CytoplasmicMembrane | 10 | |||||||
| DAMX_ECOLI | P11557 | damX yhfB | yhfB | b3388 JW3351 | integral IM protein (SEC in IM), Cell division DamX | Integral Inner Membrane | Contain a SPOR Domain. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 19880599 PMID: 21541338 PMID: 23290046 | Integral Inner Membrane | B | Binout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 68 | 0.101 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i103-124o | Unknown | 2 | |||||
| ARGO_ECOLI | P11667 | argO yggA | yggA | b2923 JW2890 | integral IM protein (SEC in IM), Arginine exporter ArgO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein(experimental) | SRP | SEC | yes | yes | N | 25 | 0.273 | TMH | 0 | 6.65864 | - | 6 | 6 | N | o6-26i38-61o67-88i109-127o147-170i182-199o | CytoplasmicMembrane | 10 | 18 | |||||
| CSRD_ECOLI | P13518 | csrD yhdA | yhdA | b3252 JW3221 | integral IM protein (SEC in IM), RNase E specificity factor CsrD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.172 | TMH | 0 | 5.84825 | - | 2 | 2 | N | i7-31o130-155i | CytoplasmicMembrane | 9 | 4 | |||||
| NHAA_ECOLI | P13738 | nhaA ant | ant | b0019 JW0018 | integral IM protein (SEC in IM), Na(+)/H(+) antiporter NhaA | Integral Inner Membrane | Structure of a Na+/H+ antiporter. A negatively charged ion funnel opens to the cytoplasm and ends in the middle of the membrane at the putative ion-binding site PMID: 15988517. | PMID: 11266632 PMID: 15919996 PMID: 15988517 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.227 | TMH | 0 | 7.93195 | - | 11 | 11 | N | i12-39o59-79i91-114o126-145i154-175o181-200i207-238o258-276i288-312o324-351i363-380o | CytoplasmicMembrane | 10 | |||||
| PROW_ECOLI | P14176 | proW | b2678 JW2653 | integral IM protein (SEC-YidC in IM), Glycine betaine/proline betaine transport system permease ProW | Integral Inner Membrane | PMID: 10949305 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 24 | 0.12 | CYT | 0 | -0.200913 | - | 6 | 6 | N | o97-118i125-143o149-171i192-219o271-291i303-320o | CytoplasmicMembrane | 10 | 5 | ||||||
| ZRAS_ECOLI | P14377 | zraS hydH | hydH | b4003 JW3967 | integral IM protein (SEC in IM), Sensor ZraS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.129 | TMH | 0 | 7.59471 | - | 2 | 2 | N | i12-35o202-222i | CytoplasmicMembrane | 10 | ||||||
| FECD_ECOLI | P15029 | fecD | b4288 JW4248 | integral IM protein (SEC in IM), Fe(3+) dicitrate transport system permease FecD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 28 | 0.121 | TMH | 0 | 10.0321 | - | 7 | 7 | Y | n4-19c31/32o55-76i85-103o109-126i138-158o226-256i268-290o296-315i | CytoplasmicMembrane | 10 | 4 | ||||||
| FECC_ECOLI | P15030 | fecC | b4289 JW4249 | integral IM protein (SEC in IM), Fe(3+) dicitrate transport system permease FecC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.15 | TMH | 0 | 7.31223 | - | 8 | 9 | Y | n8-27c36/37o60-81i93-111o117-140i152-171o177-194i201-220o240-270i282-304o310-328i | CytoplasmicMembrane | 10 | |||||||
| CSTA_ECOLI | P15078 | cstA ybdC | ybdC | b0598 JW0590 | integral IM protein (SEC-YidC in IM), Peptide transporter CstA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 21 | 0.185 | TMH | 0 | 8.48745 | - | 18 | 16 | N | i7-26o32-52i93-111o117-138i159-185o191-209i221-240o260-277i284-305o325-345i373-393o470-494i515-534o546-571i578-598o648-671i | CytoplasmicMembrane | 10 | |||||
| FLK_ECOLI | P15286 | flk div | div | b2321 JW2318 | integral IM protein (SEC in IM), regulator Flk | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 54 | 0.104 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o313-330i | CytoplasmicMembrane | 9 | 61 | |||||||
| DHG_ECOLI | P15877 | gcd | b0124 JW0120 | integral IM protein (SEC in IM), Quinoglucose dehydrogenase Gcd | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 PMID: 8419307 PMID: 8509415 PMID: 8554505 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.121 | TMH | 0 | 21.0845 | - | 5 | 5 | N | i12-35o41-58i65-81o87-106i113-140o | CytoplasmicMembrane | 9 | 18 | ||||||
| AROP_ECOLI | P15993 | aroP | b0112 JW0108 | integral IM protein (SEC-YidC in IM), Aromatic amino acid transport AroP | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 44 | 0.121 | TMH | 0 | 9.5384 | - | 12 | 12 | N | i20-41o47-63i84-105o125-142i154-176o196-220i241-263o283-300i332-353o359-379i400-422o428-446i | CytoplasmicMembrane | 10 | ||||||
| PANF_ECOLI | P16256 | panF | b3258 JW3226 | integral IM protein (SEC in IM), Sodium/pantothenate symporter PanF | Integral Inner Membrane | Prediction of one very weak transmembrane region. | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.187 | TMH | 0 | 8.73514 | - | 13 | 13 | N | o6-24i45-63o75-94i122-144o156-178i190-213o233-253i273-298o318-341i369-386o392-417i424-442o448-466i | CytoplasmicMembrane | 10 | ||||||
| HYCC_ECOLI | P16429 | hycC hevC | hevC | b2723 JW2693 | integral IM protein (SEC in IM), Formate hydrogenlyase subunit 3 HycC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.168 | TMH | 0 | 11.9962 | - | 14 | 16 | N | o6-26i33-58o78-96i108-124o130-146i153-173o197-218i230-251o257-280i292-312o332-349i370-395o415-435i456-480o500-521i587-605o | CytoplasmicMembrane | 10 | ||||||
| HYCD_ECOLI | P16430 | hycD hevD | hevD | b2722 JW2692 | integral IM protein (SEC in IM), Formate hydrogenlyase subunit 4 HycD | Integral Inner Membrane | PMID: 15919996 PMID: 1625581 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 30 | 0.198 | CYT | 0 | -0.200913 | - | 8 | 8 | N | o6-27i62-85o97-119i131-149o169-188i224-242o248-273i285-306o | CytoplasmicMembrane | 10 | ||||||
| CYST_ECOLI | P16701 | cysU cysT | cysT | b2424 JW2417 | integral IM protein (SEC-YidC in IM), Sulfate transport system permease CysT | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 37 | 0.285 | TMH | 0 | 14.8684 | - | 7 | 5 | N | o12-37i58-84o104-125i137-156o242-263i | CytoplasmicMembrane | 10 | 117 | ||||
| MREC_ECOLI | P16926 | mreC | b3250 JW3219 | integral IM protein (SEC in IM), Cell shape-determining MreC | Integral Inner Membrane | PMID: 15612918 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 25 | 0.114 | TMH | 0 | 2.1577 | - | 1 | 0 | Y | n15-23c28/29o | Unknown | 2 | 35 | ||||||
| PTQC_ECOLI | P17334 | chbC celB | celB | b1737 JW1726 | integral IM protein (SEC-YidC in IM), PTS system N,N'-diacetylchitobiose-specific EIIC component ChbC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 28 | 0.124 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i35-55o86-107i114-133o145-167i187-207o235-258i301-320o332-352i359-384o404-429i | CytoplasmicMembrane | 10 | 5 | ||||
| CYNX_ECOLI | P17583 | cynX | b0341 JW0332 | integral IM protein (SEC-YidC in IM), Cyanate transport CynX | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 55 | 0.147 | CYT | 0 | -0.200913 | - | 12 | 11 | Y | n2-10c18/19o34-55i67-85o91-113i125-147o153-173i201-224o230-251i263-281o287-309i321-339o354-372i | CytoplasmicMembrane | 10 | ||||||
| PGPA_ECOLI | P18200 | pgpA yajN | yajN | b0418 JW0408 | integral IM protein (SEC in IM), Phosphatidylglycerophosphatase A PgpA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 45 | 0.137 | TMH | 0 | 13.1049 | - | 3 | 5 | N | i21-51o57-75i87-104o110-126i138-162o | CytoplasmicMembrane | 10 | 23 | |||||
| RSTB_ECOLI | P18392 | rstB uspT | uspT | b1609 JW1601 | integral IM protein (SEC in IM), Sensor RstB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.112 | TMH | 0 | 2.20306 | - | 2 | 2 | N | o6-27i136-157o | CytoplasmicMembrane | 10 | 53 | |||||
| DMSC_ECOLI | P18777 | dmsC | b0896 JW0879 | integral IM protein (SEC in IM), Anaerobic dimethyl sulfoxide reductase chain C DmsC | Integral Inner Membrane | DMSO reductase subunit C,Periplasmic. Has a membrane bound anchor. Part of the anaerobic dimethylsulphoxide (DMSO) reductase DmsABC. The DmsC polypeptide is composed of eight segments of hydrophobic amino acids of appropriate length to cross the cytoplasmic membrane, suggesting that this subunit functions to anchor the DMSO enzyme to the membrane. PMID: 3062312 There are contradictory experiments although it seems that the senario of the DmsABC complex facing the cytoplasm is more favoured. PMID: 11389150 The localization of DmsAB was compared in a strain expressing a partial DmsC subunit (pDMSC59X) with full-length DmsC originating from the chromosomal copy of the dms operon. In those experiments some DmsAB was reported in the periplasm in the absence of full-length DmsC, leading us to suggest that DmsC might serve a stop-transfer role. PMID: 9546395 TTnphoA fusions, and electron paramagnetic resonance monitoring the effects of the probe dysprosium(III) on an engineered 3Fe4S cluster in DmsB indicated that DmsAB faces the cytoplasm PMID: 2170332 PMID: 15919996 | PMID: 11389150 PMID: 15919996 PMID: 2170332 PMID: 3062312 PMID: 9546395 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.177 | TMH | 0 | 13.558 | - | 8 | 8 | N | o12-32i44-68o88-105i117-137o149-171i183-203o223-243i255-277o | CytoplasmicMembrane | 10 | ||||||
| PTOCB_ECOLI | P19642 | malX | b1621 JW1613 | integral IM protein (SEC in IM), PTS system maltose-specific EIICB component MalX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 44 | 0.116 | TMH | 0 | 7.8693 | - | 8 | 10 | N | i21-42o62-89i96-116o136-161i182-205o295-313i320-337o343-362i369-391o397-419i | CytoplasmicMembrane | 10 | 5 | ||||||
| TOLA_ECOLI | P19934 | tolA cim excC lky | cim excC lky | b0739 JW0729 | integral IM protein (SEC in IM), Tol-Pal system TolA | Integral Inner Membrane | The N-terminal coiled coil of YbgFvforms a stable trimer and controls the oligomeric status of YbgF. The stable YbgF trimer undergoes a marked change in oligomeric state on binding TolA, forming a one-to-one complex with the Tol protein. PMID: 7744737 Disulfide bridge (363 388) Disulfide bond-containing protein PMID: 25664544 | PMID: 15919657 PMID: 20816983 PMID: 25664544 PMID: 7744737 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.131 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i12-31o | Unknown | 2 | 50 | ||||
| PTFBC_ECOLI | P20966 | fruA ptsF | ptsF | b2167 JW2154 | integral IM protein (SEC in IM), PTS system fructose-specific EIIB'BC component FruA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.169 | CYT | 0 | -0.200913 | - | 9 | 9 | N | i230-256o268-291i303-329o349-368i389-410o430-451i463-482o488-507i519-551o | CytoplasmicMembrane | 10 | 7 | |||||
| GLTP_ECOLI | P21345 | gltP | b4077 JW4038 | integral IM protein (SEC in IM), Proton/glutamate-aspartate symporter GltP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.123 | TMH | 0 | 11.2813 | - | 10 | 10 | N | i7-27o47-72i84-106o160-181i202-224o236-264i293-311o323-350i362-385o391-409i | CytoplasmicMembrane | 10 | 19 | ||||||
| YCIC_ECOLI | P21365 | yciC | b1255 JW1247 | integral IM protein (SEC in IM), UPF0259 YciC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.196 | TMH | 0 | 6.50025 | - | 6 | 6 | N | i20-41o77-104i116-136o142-166i187-212o218-239i | CytoplasmicMembrane | 10 | |||||||
| YCAD_ECOLI | P21503 | ycaD | b0898 JW0881 | integral IM protein (SEC in IM), MFS-type transporter YcaD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.154 | TMH | 0 | 14.4924 | - | 12 | 11 | Y | n10-18c23/24o47-65i74-92o98-119i131-149o161-181i202-223o235-253i265-283o289-311i323-345o351-369i | CytoplasmicMembrane | 10 | |||||||
| KDPD_ECOLI | P21865 | kdpD | b0695 JW0683 | integral IM protein (SEC in IM), Sensor KdpD | Integral Inner Membrane | PMID: 1532388 PMID: 15919996 PMID: 21605551 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 46 | 0.149 | CYT | 0 | -0.200913 | - | 4 | 4 | N | i399-419o425-443i448-465o477-498i | CytoplasmicMembrane | 10 | 22 | ||||||
| FLIO_ECOLI | P22586 | fliO flaP flbD | flaP flbD | b1947 JW5316 | Flagellar integral IM protein (SEC in IM), FliO | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell membrane | Membrane anchored | flagellum | SRP | SEC | no | yes | N | 27 | 0.161 | TMH | 0 | 0.0866025 | - | 1 | 1 | N | o18-39i | CytoplasmicMembrane | 9 | 14 | ||||||
| LIVM_ECOLI | P22729 | livM | b3456 JW3421 | integral IM protein (SEC in IM), High-affinity branched-chain amino acid transport system permease LivM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.39 | SpI | 20 | 11.5293 | - | 10 | 10 | Y | n9-20c25/26o44-61i91-108o114-132i137-156o162-184i191-209o262-283i313-336o348-373i385-403o | CytoplasmicMembrane | 10 | |||||||
| TNAB_ECOLI | P23173 | tnaB trpP | trpP | b3709 JW5619/JW5622 | integral IM protein (SEC in IM), Low affinity tryptophan permease TnaB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 25 | 0.14 | TMH | 0 | 16.6914 | - | 11 | 11 | N | i12-32o38-61i82-105o125-143i155-174o194-219i226-246o282-310i322-341o347-369i381-406o | CytoplasmicMembrane | 10 | 5 | |||||
| MGLC_ECOLI | P23200 | mglC | b2148 JW2135 | integral IM protein (SEC in IM), Galactoside transport system permease MglC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.106 | TMH | 0 | 5.37465 | - | 9 | 8 | N | i12-31o43-64i105-129o135-155i175-201o227-248i269-299o311-330i | CytoplasmicMembrane | 10 | |||||||
| HYFB_ECOLI | P23482 | hyfB yffF | yffF | b2482 JW2467 | integral IM protein (SEC in IM), Hydrogenase-4 component B HyfB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 57 | 0.166 | TMH | 0 | 7.57984 | - | 16 | 16 | N | o6-27i39-62o82-103i110-129o135-154i166-185o205-224i245-267o273-296i303-326o332-363i383-405o425-452i473-496o532-551i652-671o | CytoplasmicMembrane | 10 | ||||||
| FECR_ECOLI | P23485 | fecR | b4292 JW4252 | integral IM protein (SEC in IM), FecR | Integral Inner Membrane | The protein is oriented such that residues 1 to 85 are in the cytoplasm, residues 86 to 100 form a transmembrane segment, and residues 101 to 317 are in the periplasm where the C-terminus can interact with the N-domain of the outer membrane protein FecA. | PMID: 12057967 PMID: 9573190 | Integral Inner Membrane | B | - | IM (predicted-detected) | Periplasm | Integral Membrane Protein | SRP | SEC | no | yes | N | 35 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Periplasmic | 10 | |||||||
| PHOQ_ECOLI | P23837 | phoQ | b1129 JW1115 | integral IM protein (SEC in IM), Sensor PhoQ | Integral Inner Membrane | PMID: 15919996 PMID: 23359663 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.287 | TMH | 0 | 6.14229 | - | 2 | 1 | Y | n17-28c33/34o194-216i | CytoplasmicMembrane | 10 | 20 | ||||||
| PDEA_ECOLI | P23842 | pdeA yfeA | yfeA | b2395 JW5391 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 45 | 0.113 | TMH | 0 | 9.46751 | - | 8 | 9 | N | o12-31i43-61o81-104i125-143o163-186i214-232o238-255i262-279o291-312i | CytoplasmicMembrane | 10 | ||||||
| TRKG_ECOLI | P23849 | trkG | b1363 JW1358 | integral IM protein (SEC in IM), Trk system potassium uptake TrkG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | yes | no | N | 32 | 0.135 | TMH | 0 | 11.2875 | - | 11 | 11 | N | i12-34o40-60i72-93o139-164i185-206o239-263i275-296o336-356i399-418o424-446i458-483o | CytoplasmicMembrane | 10 | ||||||
| FEPD_ECOLI | P23876 | fepD | b0590 JW0582 | integral IM protein (SEC in IM), Ferric enterobactin transport system permease FepD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.205 | TMH | 0 | 1.30983 | - | 9 | 9 | N | o6-30i64-81o93-114i121-139o151-172i193-213o239-264i284-304o310-326i | CytoplasmicMembrane | 10 | |||||||
| FEPG_ECOLI | P23877 | fepG | b0589 JW0581 | integral IM protein (SEC in IM), Ferric enterobactin transport system permease FepG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.416 | TMH | 0 | 10.9363 | - | 8 | 8 | Y | n8-23c41/42o65-83i95-112o118-138i145-167o187-211i236-262o274-296i303-324o | CytoplasmicMembrane | 10 | |||||||
| CYDC_ECOLI | P23886 | cydC mdrA mdrH surB | mdrA mdrH surB | b0886 JW0869 | integral IM protein (SEC in IM), ATP-binding/permease CydC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 50 | 0.199 | TMH | 0 | 16.2776 | - | 6 | 6 | N | i16-35o41-61i133-155o161-182i243-266o278-301i | CytoplasmicMembrane | 10 | 10 | |||||
| CADC_ECOLI | P23890 | cadC | b4133 JW4094 | nucleoid & integral IM protein (SEC in IM), Transcriptional activator CadC | Integral Inner Membrane, Nucleoid | Membrane-integrated pH sensor. The membrane-integrated transcriptional activator CadC of Escherichia coli senses lysine indirectly via the interaction with the lysine permease LysP. | PMID: 18086202 PMID: 21890895 PMID: 23138451 PMID: 24056175 | Integral Inner Membrane, Nucleoid | B, N | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 50 | 0.131 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o159-181i | CytoplasmicMembrane | 9 | ||||||||
| HTPX_ECOLI | P23894 | htpX | b1829 JW1818 | integral IM protein (SEC in IM), Protease HtpX | Integral Inner Membrane | PMID: 12081643 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.141 | TMH | 0 | 12.8648 | - | 4 | 3 | Y | n4-18c23/24o33-53i158-178o193-217i | CytoplasmicMembrane | 10 | 8 | ||||||
| EMRE_ECOLI | P23895 | emrE eb mvrC | eb mvrC | b0543 JW0531 | integral IM protein (SEC-YidC in IM), Multidrug transporter EmrE | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. Dual topology membrane protein: can insert into the membrane in both directions. PMID: 15919996 | PMID: 15919996 PMID: 16429150 PMID: 20508091 PMID: 22108384 PMID: 22178925 PMID: 22444835 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | in/out, out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | Prophage Integrase (EcoGene), pseudogene (Ochman & Davalos, 2006) | no | no | N | 62 | 0.162 | TMH | 0 | 6.32256 | - | 4 | 3 | N | o30-48i60-79o85-104i | CytoplasmicMembrane | 10 | 7 | |||
| ARAJ_ECOLI | P23910 | araJ | b0396 JW0386 | integral IM protein (SEC in IM), Putative transporter AraJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.21 | TMH | 0 | 4.92502 | - | 12 | 11 | Y | n4-15c20/21o44-63i70-96o102-120i127-150o156-178i199-219o225-251i263-284o290-310i331-350o356-375i | CytoplasmicMembrane | 10 | |||||||
| LNT_ECOLI | P23930 | lnt cutE | cutE | b0657 JW0654 | integral IM protein (SEC in IM), ApoN-acyltransferase Lnt | Integral Inner Membrane | PMID: 15919996 PMID: 2032623 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.184 | TMH | 0 | 13.3696 | - | 6 | 8 | N | i12-28o34-50i57-79o91-112i124-142o162-188i195-214o489-507i | CytoplasmicMembrane | 10 | 2 | |||||
| ENTS_ECOLI | P24077 | entS ybdA | ybdA | b0591 JW0583 | integral IM protein (SEC in IM), Enterobactin exporter EntS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.337 | TMH | 0 | 10.2914 | - | 11 | 12 | N | i21-42o54-74i86-105o111-135i147-170o176-199i219-246o258-276i288-305o311-336i357-374o380-399i | CytoplasmicMembrane | 10 | ||||||
| ACRD_ECOLI | P24177 | acrD yffA | yffA | b2470 JW2454 | integral IM protein (SEC-YidC in IM), Probable aminoglycoside efflux pump AcrD | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 35 | 0.15 | SpI | 34 | 5.86063 | - | 11 | 11 | Y | n10-21c26/27o340-359i366-387o393-413i438-458o470-497i538-558o873-890i897-917o923-944i972-992o1004-1026i | CytoplasmicMembrane | 10 | |||||
| ACRF_ECOLI | P24181 | acrF envD | envD | b3266 JW3234 | integral IM protein (SEC in IM), Multidrug export AcrF | Integral Inner Membrane | PMID: 11274125 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.286 | SpI | 26 | 12.2125 | - | 12 | 11 | Y | n10-21c26/27o340-359i366-390o396-416i437-458o470-497i541-558o872-891i898-918o924-948i969-990o1002-1028i | CytoplasmicMembrane | 10 | ||||||
| LPXM_ECOLI | P24205 | lpxM msbB | msbB | b1855 JW1844 | integral IM protein (SEC in IM), Lipid A biosynthesis myristoyltransferase LpxM | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 45 | 0.121 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o24-43i | CytoplasmicMembrane | 10 | 16 | |||||||
| PHEP_ECOLI | P24207 | pheP | b0576 JW0565 | integral IM protein (SEC in IM), Phenylalanine-specific permease PheP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 53 | 0.106 | TMH | 0 | 1.83401 | - | 12 | 12 | N | i30-49o55-71i107-130o136-156i163-184o204-228i249-271o291-308i340-361o367-387i408-428o434-452i | CytoplasmicMembrane | 10 | |||||||
| PTIBC_ECOLI | P24241 | ascF | b2715 JW5435 | integral IM protein (SEC-YidC in IM), PTS system arbutin-, cellobiose-, and salicin-specific EIIBC component AscF | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 25 | 0.128 | CYT | 0 | -0.200913 | - | 8 | 10 | N | i104-127o147-167i179-197o217-234i254-282o288-309i330-350o362-382i389-413o433-456i | CytoplasmicMembrane | 10 | 7 | |||||
| APPX_ECOLI | P24244 | appX yccB | yccB | b4592 JW0961.1 b0979.1 | integral IM protein (SEC in IM), Putative cytochrome bd-II ubiquinol oxidase subunit AppX | Integral Inner Membrane | Experimentally verified orientation: N(out)-C(in). | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | out/in | N/A | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.107 | TMH | 0 | 2.07613 | - | 1 | 1 | N | o6-24i | CytoplasmicMembrane | 9 | |||||
| TEHA_ECOLI | P25396 | tehA | b1429 JW1425 | integral IM protein (SEC in IM), Tellurite resistance TehA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.119 | TMH | 0 | 12.0389 | - | 8 | 10 | N | i12-31o43-64i76-97o103-121i141-160o166-184i196-218o230-249i256-274o286-310i | CytoplasmicMembrane | 10 | |||||||
| GABP_ECOLI | P25527 | gabP | b2663 JW2638 | integral IM protein (SEC in IM), GABA permease GabP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.302 | TMH | 0 | 8.50646 | - | 12 | 12 | N | i21-40o46-66i97-118o124-144i156-180o200-220i241-264o284-308i335-354o360-380i401-423o429-449i | CytoplasmicMembrane | 10 | |||||||
| YIDC_ECOLI | P25714 | yidC | b3705 JW3683 | integral IM protein (SEC in IM), insertase YidC | Integral Inner Membrane | YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. The first periplasmic region of YidC include residues 24???346. Residues 215???265 of YidC are sufficient for SecF binding. The interaction of YidC with SecF is though not critical for cell viability as YidC, lacking residues 24-264, was fully functional to support the growth of <i>E. coli</i>. The integration of YidC into the cytoplasmic membrane requires the signal recognition particle, SecA and SecYEG. | PMID: 10675323 PMID: 11777926 PMID: 11821429 PMID: 15919657 PMID: 16079137 PMID: 17073462 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 25 | 0.321 | SpI | 24 | 12.0898 | - | 4 | 4 | Y | n7-17c24/25o354-373i417-440o464-482i494-519o | CytoplasmicMembrane | 10 | 26 | |||||
| LYSP_ECOLI | P25737 | lysP cadR | cadR | b2156 JW2143 | integral IM protein (SEC in IM), Lysine-specific permease LysP | Integral Inner Membrane | Lysine-specific permease LysP and the membrane-integrated pH sensor CadC induce lysine-dependent adaptation of E. coli under acidic stress. In absence of lysine or high low pH LysP and CadC form stable complex. Probably CadC is inhibited by LysP via intramembrane and periplasmic contacts under non-inducing conditions. The membrane-integrated transcriptional activator CadC of Escherichia coli senses lysine indirectly via the interaction with the lysine permease LysP. | PMID: 15919996 PMID: 18086202 PMID: 24056175 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.175 | TMH | 0 | 10.7386 | - | 12 | 12 | N | i21-43o49-66i103-125o131-149i161-182o202-224i245-267o287-312i348-365o371-394i415-435o447-467i | CytoplasmicMembrane | 10 | |||||
| YCHE_ECOLI | P25743 | ychE | b1242 JW1229 | integral IM protein (SEC in IM), UPF0056 YchE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.169 | TMH | 0 | 10.9574 | - | 6 | 6 | N | o12-32i52-72o78-97i118-141o147-168i189-210o | CytoplasmicMembrane | 10 | 13 | ||||||
| MDTG_ECOLI | P25744 | mdtG yceE | yceE | b1053 JW1040 | integral IM protein (SEC in IM), Multidrug resistance MdtG | Integral Inner Membrane | PMID: 11566977 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein(experimental) | SRP | SEC | no | yes | N | 32 | 0.145 | TMH | 0 | 16.0858 | - | 10 | 10 | N | i16-40o52-74i86-104o110-130i142-162o174-193i220-245o257-278i290-308o374-393i | CytoplasmicMembrane | 10 | ||||||
| YEIB_ECOLI | P25747 | yeiB | b2152 JW2139 | integral IM protein (SEC in IM), YeiB | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.167 | TMH | 0 | 9.38597 | - | 10 | 10 | N | i9-28o48-71i83-101o107-122i134-153o201-221i233-254o274-292i312-332o338-359i | CytoplasmicMembrane | 10 | |||||||||
| FLIF_ECOLI | P25798 | fliF fla AII.1 fla BI | fla AII.1 fla BI | b1938 JW1922 | Flagellar integral IM protein (SEC in IM), M-ring protein FliF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | flagellum | SRP | SEC | no | yes | N | 46 | 0.141 | SpI | 43 | 3.78777 | - | 2 | 2 | N | i23-43o451-468i | CytoplasmicMembrane | 10 | 54 | ||||
| LEP4_ECOLI | P25960 | gspO hofD hopD hopO yheC | hofD hopD hopO yheC | b3335 JW3297 | integral IM protein (SEC in IM), Type 4 prepilin-like proteins leader peptide-processing enzyme GspO | Integral Inner Membrane | Part of gsp locus. PMID: 15919996 | PMID: 11118204 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 24 | 0.153 | TMH | 0 | 0.982152 | - | 7 | 5 | Y | n4-15c21/22o55-84i104-122o128-149i161-191o203-222i | CytoplasmicMembrane | 10 | |||||
| FEPE_ECOLI | P26266 | fepE | b0587 JW0579 | integral IM protein (SEC in IM), Ferric enterobactin transport FepE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 46 | 0.11 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i42-61o339-362i | CytoplasmicMembrane | 10 | 33 | ||||||
| APPB_ECOLI | P26458 | appB cbdB cyxB | cbdB cyxB | b0979 JW0961 | integral IM protein (SEC in IM), Cytochrome bd-II ubiquinol oxidase subunit 2 AppB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.107 | TMH | 0 | 10.1949 | - | 8 | 9 | N | o12-40i61-79o85-103i123-148o168-188i209-233o263-283i290-314o334-356i | CytoplasmicMembrane | 10 | ||||||
| APPC_ECOLI | P26459 | appC cbdA cyxA | cbdA cyxA | b0978 JW0960 | integral IM protein (SEC-YidC in IM), Cytochrome bd-II ubiquinol oxidase subunit 1 AppC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 37 | 0.11 | TMH | 0 | 11.9815 | - | 9 | 9 | N | o20-42i54-71o91-116i128-145o184-208i215-235o386-409i421-442o471-492i | CytoplasmicMembrane | 10 | |||||
| PLSC_ECOLI | P26647 | plsC parF | parF | b3018 JW2986 | integral IM protein (SEC in IM), 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC | Integral Inner Membrane | PMID: 1557036 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored (Experimental) | SEC | yes | yes | N | 36 | 0.111 | TMH | 0 | 1.55803 | - | 1 | 1 | N | o6-27i | CytoplasmicMembrane | 10 | 28 | ||||||
| RHAT_ECOLI | P27125 | rhaT | b3907 JW3878 | integral IM protein (SEC in IM), L-rhamnose-proton symporter RhaT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) , Soluble IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 20 | 0.227 | TMH | 0 | 12.7916 | - | 10 | 10 | N | o6-26i38-58o64-85i97-121o133-154i175-194o214-234i255-277o289-310i322-343o | CytoplasmicMembrane | 10 | |||||||
| RFAL_ECOLI | P27243 | rfaL waaL | waaL | b3622 JW3597 | integral IM protein (SEC in IM), O-antigen ligase RfaL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.114 | TMH | 0 | 0.404949 | - | 12 | 12 | N | i20-38o44-60i72-91o103-122i134-152o172-189i196-212o218-233i240-258o349-368i375-393o399-415i | CytoplasmicMembrane | 10 | ||||||
| LPXK_ECOLI | P27300 | lpxK ycaH | ycaH | b0915 JW0898 | integral IM protein (SEC in IM), Tetraacyldisaccharide 4'-kinase LpxK | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | no | yes | N | 44 | 0.107 | TMH | 0 | 1.00613 | - | 1 | 1 | N | o12-34i | Unknown | 2 | 30 | ||||||||
| EMRA_ECOLI | P27303 | emrA | b2685 JW2660 | integral IM protein (SEC in IM), Multidrug export EmrA | Integral Inner Membrane | PMID: 12482849 PMID: 1409590 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 38 | 0.157 | TMH | 0 | 6.79297 | - | 1 | 1 | N | i23-44o | CytoplasmicMembrane | 10 | 25 | ||||||
| RODZ_ECOLI | P27434 | rodZ yfgA | yfgA | b2516 JW2500 | nucleoid & integral IM protein (SEC in IM), Cytoskeleton RodZ | Integral Inner Membrane, Nucleoid | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. Quantitative immunoblotting agaist RodZ purified protein indicate that RodZ is present at ~650 copies per average exponentially growing cell in LB medium and M9. The hth domain of RodZ is not required for transcription but for interaction with MreB. The protein, RodZ, is required for assembly of the actin cytoskeleton MreB that controls cell wall synthesis and cell shape. PMID: 19194484 | PMID: 15919657 PMID: 19008860 PMID: 19078962 PMID: 19194484 PMID: 21890895 PMID: 23138451 PMID: 9008159 PMCID: PMC2637328 | Integral Inner Membrane, Nucleoid | B, N | IM (predicted) | Cell inner membrane | Membrane anchored | SEC | yes | yes | N | 35 | 0.243 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i112-133o | Unknown | 2 | ||||||||
| WZYE_ECOLI | P27835 | wzyE wzy | wzy | b3793 JW3769 | integral IM protein (SEC in IM), Probable ECA polymerase WzyE | Integral Inner Membrane | PMID: 16816184 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.116 | TMH | 0 | 14.4283 | - | 11 | 11 | N | o6-26i38-58o70-88i115-137o157-175i182-199o205-220i227-245o337-361i381-398o410-430i | CytoplasmicMembrane | 10 | ||||||
| YIFK_ECOLI | P27837 | yifK | b3795 JW5595 | integral IM protein (SEC in IM), Probable transport YifK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.143 | TMH | 0 | 8.10925 | - | 12 | 12 | N | i12-34o40-60i94-119o125-146i158-177o197-219i240-259o271-299i333-353o359-380i401-423o429-448i | CytoplasmicMembrane | 10 | 31 | ||||||
| YIGF_ECOLI | P27842 | yigF | b3817 JW3790 | integral IM protein (SEC in IM), YigF | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | no | yes | N | 40 | 0.108 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i52-72o78-107i | CytoplasmicMembrane | 9 | 25 | |||||||||
| YIGG_ECOLI | P27843 | yigG | b3818 JW5590 | integral IM protein (SEC in IM), YigG | Integral Inner Membrane | PMID: 11867724 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 42 | 0.121 | TMH | 0 | 5.14332 | - | 4 | 4 | N | i18-35o41-57i69-91o103-121i | CytoplasmicMembrane | 10 | |||||||
| RARD_ECOLI | P27844 | rarD | b3819 JW5589 | integral IM protein (SEC in IM), RarD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.239 | TMH | 0 | 9.7991 | - | 10 | 10 | N | i12-31o43-61i73-92o104-121i128-145o151-167i179-198o210-230i242-261o273-290i | CytoplasmicMembrane | 10 | |||||||
| NARQ_ECOLI | P27896 | narQ | b2469 JW2453 | integral IM protein (SEC in IM), Nitrate/nitrite sensor NarQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.145 | TMH | 0 | 1.10259 | - | 2 | 2 | N | o14-34i147-169o | CytoplasmicMembrane | 10 | 7 | ||||||
| BCR_ECOLI | P28246 | bcr bicA bicR sur suxA | bicA bicR sur suxA | b2182 JW5363 | integral IM protein (SEC-YidC in IM), Bicyclomycin resistance Bcr | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 33 | 0.128 | TMH | 0 | 13.9575 | - | 12 | 12 | N | i7-26o46-65i77-96o102-123i135-159o165-185i215-241o253-273i285-307o313-332i344-366o372-391i | CytoplasmicMembrane | 10 | |||||
| ASMA_ECOLI | P28249 | asmA yegA | yegA | b2064 JW2049 | integral IM protein (SEC in IM), AsmA | Integral Inner Membrane | Involved in outer memebrane protein assembly and has an apparent signal peptide. It has been predicted to be periplasmic or outer membrane protein but detailed sub-fractionation studies revealed that it is localized to the inner membranePMID: 8866482. Reduced LPS levels in asmA mutants indicate a possible role of AsmA in LPS biogenesis. | PMID: 19346309 PMID: 7476172 PMID: 8866482 PMCID: PMC178309 | Integral Inner Membrane | B | Bout | in/out | N/A | Periplasm | Membrane anchored | SRP | SEC | yes | yes | N | 26 | 0.141 | TMH | 0 | 10.2137 | - | 1 | 0 | Y | n4-16c21/22o | Unknown | 2 | 69 | ||||
| DINF_ECOLI | P28303 | dinF | b4044 JW4004 | integral IM protein (SEC in IM), DNA damage-inducible F DinF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.258 | TMH | 0 | 3.41253 | - | 13 | 13 | N | o6-22i29-49o61-83i103-124o152-173i180-199o205-227i259-278o284-302i338-359o371-393i405-422o428-446i | CytoplasmicMembrane | 10 | 10 | ||||||
| MLTG_ECOLI | P28306 | mltG yceG | yceG | b1097 JW1083 | integral IM protein (SEC in IM), Endolytic murein transglycosylase MltG | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 20 | 0.198 | SpI | 18 | 0.538854 | - | 1 | 0 | Y | n4-15c20/21o | Unknown | 6 | 16 | |||||||
| YHHH_ECOLI | P28911 | yhhH | b3483 JW3449 | integral IM protein (SEC in IM), YhhH | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 32 | 0.366 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i12-30o | Unknown | 2 | 52 | |||||||||
| CYDD_ECOLI | P29018 | cydD htrD | htrD | b0887 JW0870 | integral IM protein (SEC-YidC in IM), ATP-binding/permease CydD | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919657 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 43 | 0.111 | TMH | 0 | 0.800558 | - | 5 | 6 | N | i29-49o61-82i140-159o165-188i245-272o278-297i | CytoplasmicMembrane | 10 | |||||
| FTSN_ECOLI | P29131 | ftsN msgA | msgA | b3933 JW3904 | integral IM protein (SEC in IM), Cell division FtsN | Integral Inner Membrane | Localizes to potential division sites in filamentous cells. FtsN interacts directly with itself, FtsW, FtsI and ZapA. | PMID: 11703663 PMID: 20497333 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 41 | 0.126 | SpI | 40 | 0.332384 | - | 1 | 1 | N | i29-54o | CytoplasmicMembrane | 10 | 23 | ||||
| THIF_ECOLI | P30138 | thiF | b3992 JW3956 | integral IM protein (SEC in IM), Sulfur carrier ThiS adenylyltransferase ThiF | Integral Inner Membrane | Very strong TMHMM and Phobius and Kyte/Doolittle predictions for at least one TM region. Proteins that have activities as nucleoside-triphosphatase and hydrolysis of thiamin triphosphate in Escherichia coli have been shown to be membrane-bound but there is no experimental evidence for ThiF PMID: 3026493. | PMID: 3026493 | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | yes | yes | N | 59 | 0.161 | CYT | 0 | -0.200913 | - | 1 | 0 | N | i | Cytoplasmic | 9 | 45 | ||||||
| YAAJ_ECOLI | P30143 | yaaJ | b0007 JW0006 | integral IM protein (SEC in IM), transporter YaaJ | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.113 | TMH | 0 | 10.2038 | - | 9 | 9 | N | o12-30i68-87o93-116i137-156o176-194i206-228o297-321i342-370o414-438i | CytoplasmicMembrane | 10 | |||||||||
| YABI_ECOLI | P30149 | yabI | b0065 JW5005 | integral IM protein (SEC in IM) of DedA family, YabI | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. PMID: 15919996 | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 43 | 0.146 | TMH | 0 | 11.6076 | - | 5 | 5 | N | i12-36o56-79i145-165o177-196i217-236o | CytoplasmicMembrane | 10 | 17 | |||||
| BASS_ECOLI | P30844 | basS pmrB | pmrB | b4112 JW4073 | integral IM protein (SEC-YidC in IM), Sensor BasS | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 35 | 0.113 | TMH | 0 | 3.38744 | - | 2 | 2 | N | i14-34o65-85i | CytoplasmicMembrane | 10 | 20 | ||||
| EPTA_ECOLI | P30845 | eptA pmrC yjdB | pmrC yjdB | b4114 JW5730 | integral IM protein (SEC in IM), Phosphoethanolamine transferase EptA | Integral Inner Membrane | YjdB co-localizes with the ZipA protein and is involved in cell division. Has been purified as a complex with ZipA-EptA. | PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.157 | TMH | 0 | 13.2858 | - | 5 | 5 | N | i12-33o45-66i78-100o120-142i154-176o | CytoplasmicMembrane | 10 | |||||
| BAES_ECOLI | P30847 | baeS | b2078 JW2063 | integral IM protein (SEC-YidC in IM), Signal transduction histidine-kinase BaeS | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 31 | 0.161 | TMH | 0 | 6.32525 | - | 2 | 2 | N | i12-31o168-186i | CytoplasmicMembrane | 10 | 31 | |||||
| EVGS_ECOLI | P30855 | evgS | b2370 JW2367 | integral IM protein (SEC in IM), Sensor EvgS | Integral Inner Membrane | Potential substrate of periplasmic chaperone YfgM. PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 25403562 | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | YfgM | no | yes | Y | 22 | 0.874 | SpI | 21 | 7.57923 | - | 0 | 1 | Y | n3-14c21/22o536-558i | CytoplasmicMembrane | 9 | |||||
| YEDE_ECOLI | P31064 | yedE | b1929 JW1914 | integral IM protein (SEC in IM), UPF0394 YedE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.167 | TMH | 0 | 16.7358 | - | 10 | 10 | N | i12-32o81-100i112-136o148-171i197-215o221-240i260-280o292-314i321-341o361-382i | CytoplasmicMembrane | 10 | |||||||
| KCH_ECOLI | P31069 | kch | b1250 JW1242 | integral IM protein (SEC in IM), Voltage-gated potassium channel Kch | Integral Inner Membrane | PMID: 15919996 PMID: 8824224 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.106 | TMH | 0 | 2.91162 | - | 7 | 6 | N | i21-39o59-80i87-104o110-127i139-161o200-225i | CytoplasmicMembrane | 10 | |||||||
| AAS_ECOLI | P31119 | aas | b2836 JW2804 | integral IM protein (SEC-YidC in IM), Bifunctional Aas Aas | Integral Inner Membrane | Integral membrane protein (experimental; from GenProtEC) Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/out | Soluble IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 57 | 0.217 | CYT | 0 | -0.200913 | - | 0 | 2 | N | o258-277i415-438o | CytoplasmicMembrane | 10 | 7 | |||||
| SOTB_ECOLI | P31122 | sotB ydeA | ydeA | b1528 JW1521 | integral IM protein (SEC in IM), Sugar efflux transporter SotB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.15 | TMH | 0 | 12.9623 | - | 12 | 12 | N | i12-36o48-68i80-99o105-126i138-156o168-189i210-232o244-265i272-293o299-321i333-352o364-384i | CytoplasmicMembrane | 10 | ||||||
| EAMA_ECOLI | P31125 | eamA ydeD | ydeD | b1533 JW5250 | integral IM protein (SEC-YidC in IM), Probable amino-acid metabolite efflux pump EamA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 37 | 0.113 | TMH | 0 | 10.8414 | - | 10 | 10 | N | i7-27o33-52i61-82o88-108i117-135o141-161i173-196o216-237i244-263o269-289i | CytoplasmicMembrane | 10 | 4 | ||||
| YDEE_ECOLI | P31126 | ydeE ydeF | ydeF | b1534 JW1527 | integral IM protein (SEC in IM), MFS-type transporter YdeE | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.123 | TMH | 0 | 10.3798 | - | 12 | 11 | Y | n8-19c24/25o44-63i75-93o99-121i133-156o162-182i207-233o245-263i275-293o299-323i335-357o363-381i | CytoplasmicMembrane | 10 | 94 | |||||||
| POTH_ECOLI | P31135 | potH | b0856 JW0840 | integral IM protein (SEC in IM), Putrescine transport system permease PotH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 58 | 0.132 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i31-52o103-122i134-155o185-208i229-253o284-305i | CytoplasmicMembrane | 10 | |||||||
| ACRB_ECOLI | P31224 | acrB acrE | acrE | b0462 JW0451 | integral IM protein (SEC-YidC in IM), Multidrug efflux pump subunit AcrB | Integral Inner Membrane | AcrB is a major multidrug exporter in Escherichia coli. It cooperates with a membrane fusion protein, AcrA, and an outer membrane channel, TolC (AcrAB-TolC multidrug efflux system) PMID: 15228545. Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertionPMID: 9008159. Exhibites aberrant localization by microscopy in the absence of YidCPMID: 22108384. Crystal structure of AcrB shows three AcrB protomers are organized as a homotrimer in the shape of a jellyfish. In the transmembrane region, each protomer has twelve transmembrane alpha-helicesPMID: 12374972. | PMID: 11266632 PMID: 12374972 PMID: 15228545 PMID: 15919996 PMID: 16079137 PMID: 22108384 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC-YidC | yes | yes | N | 55 | 0.156 | TMH | 0 | 4.86972 | - | 11 | 12 | N | i12-32o340-359i366-390o396-416i437-458o470-493i541-557o875-892i899-919o925-946i975-995o1007-1029i | CytoplasmicMembrane | 10 | |||||
| YICH_ECOLI | P31433 | yicH | b3655 JW3630 | integral IM protein (SEC in IM), YicH | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Membrane anchored | SRP | SEC | yes | yes | N | 33 | 0.134 | TMH | 0 | 7.0277 | - | 1 | 1 | N | i7-26o | Unknown | 2 | 7 | |||||||||
| YICJ_ECOLI | P31435 | yicJ | b3657 JW5939 | integral IM protein (SEC in IM), symporter YicJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 57 | 0.115 | TMH | 0 | 2.46347 | - | 11 | 12 | N | i12-34o40-58i79-98o110-132i152-174o180-202i232-258o264-283i295-313o319-342i363-390o402-424i | CytoplasmicMembrane | 10 | |||||||
| SETC_ECOLI | P31436 | setC yicK | yicK | b3659 JW3633 | integral IM protein (SEC in IM), Sugar efflux transporter C SetC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.244 | TMH | 0 | 9.2462 | - | 12 | 11 | Y | n14-25c33/34o49-70i82-100o106-129i141-161o173-193i221-238o258-277i284-308o314-331i352-368o374-391i | CytoplasmicMembrane | 10 | ||||||
| YICL_ECOLI | P31437 | yicL | b3660 JW3634 | integral IM protein (SEC in IM), transporter YicL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.389 | TMH | 0 | 7.96611 | - | 10 | 9 | Y | n11-18c25/26o41-60i72-94o100-120i127-146o152-172i184-205o217-237i249-270o276-293i | CytoplasmicMembrane | 10 | |||||||
| ADEQ_ECOLI | P31440 | adeQ yicO | yicO | b3664 JW5636 | integral IM protein (SEC in IM), Adenine permease AdeQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 57 | 0.125 | CYT | 0 | -0.200913 | - | 13 | 12 | N | o33-51i63-86o98-131i143-161o181-199i206-227o247-267i296-318o330-350i357-377o389-413i425-443o | CytoplasmicMembrane | 10 | ||||||
| EMRD_ECOLI | P31442 | emrD yicQ | yicQ | b3673 JW5634 | integral IM protein (SEC-YidC in IM), Multidrug resistance D EmrD | Integral Inner Membrane | EmrD is a multidrug transporter from the Major Facilitator Superfamily that expels amphipathic compounds across the inner membrane of Escherichia coli. Crystal structure of EmrD reveals an interior that is composed mostly of hydrophobic residues, which is consistent with its role transporting amphipathic molecules. Two long loops extend into the inner leaflet side of the cell membrane.PMID: 16675700. Exhibites aberrant localization by microscopy in the absence of YidCPMID: 22108384. | PMID: 11266632 PMID: 15919996 PMID: 16675700 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 24 | 0.319 | SpI | 23 | 9.69754 | - | 12 | 11 | Y | n9-20c25/26o44-63i75-92o98-116i136-159o165-183i203-226o232-261i273-291o297-318i330-353o365-383i | CytoplasmicMembrane | 10 | |||||
| YIDI_ECOLI | P31446 | yidI | b3677 JW3653 | integral IM protein (SEC in IM), YidI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 36 | 0.149 | TMH | 0 | 0.964289 | - | 3 | 3 | N | i12-30o78-98i110-143o | CytoplasmicMembrane | 10 | 27 | ||||||
| YIDK_ECOLI | P31448 | yidK | b3679 JW3655 | integral IM protein (SEC in IM), symporter YidK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 23 | 0.12 | CYT | 0 | -0.200913 | - | 15 | 15 | N | o6-22i34-56o76-98i119-141o161-180i192-212o242-261i282-307o327-349i381-397o409-427i434-454o460-481i506-526o532-550i | CytoplasmicMembrane | 10 | |||||||
| PTXC_ECOLI | P31452 | glvC | b3683 JW3660 | integral IM protein (SEC in IM), Phosphotransferase IIC component GlvC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | N | 51 | 0.159 | TMH | 0 | 11.5504 | - | 9 | 10 | N | i12-32o63-80i87-109o129-153i174-194o206-222i234-255o275-298i305-323o329-356i | CytoplasmicMembrane | 10 | ||||||
| MDTL_ECOLI | P31462 | mdtL yidY | yidY | b3710 JW3688 | integral IM protein (SEC in IM), Multidrug resistance MdtL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.157 | TMH | 0 | 2.89051 | - | 11 | 11 | Y | n4-12c16/17o40-58i70-89o95-116i128-152o158-178i199-222o242-262i269-287o293-312i324-345o351-376i | CytoplasmicMembrane | 10 | ||||||
| ADEP_ECOLI | P31466 | adeP purP yieG | purP yieG | b3714 JW3692 | integral IM protein (SEC in IM), Adenine permease AdeP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 12 | 0.099 | TMH | 0 | 0.786304 | - | 13 | 13 | N | i32-56o62-81i88-106o112-130i142-161o181-199i206-226o246-266i295-317o329-349i356-376o388-412i424-442o | CytoplasmicMembrane | 10 | ||||||
| CBRB_ECOLI | P31468 | cbrB yieI | yieI | b3716 JW3694 | integral IM protein (SEC in IM), CbrB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 34 | 0.114 | TMH | 0 | 14.4652 | - | 4 | 4 | N | i12-32o38-69i81-100o120-138i | CytoplasmicMembrane | 10 | 25 | |||||
| HSRA_ECOLI | P31474 | hsrA yieO | yieO | b3754 JW3733 | integral IM protein (SEC in IM), Probable transport HsrA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.237 | TMH | 0 | 8.54455 | - | 14 | 13 | Y | n10-21c27/28o51-71i78-97o103-124i136-158o164-182i194-211o223-244i264-287o293-314i326-347o353-374i394-417o429-450i | CytoplasmicMembrane | 10 | ||||||
| METI_ECOLI | P31547 | metI yaeE | yaeE | b0198 JW0194 | integral IM protein (SEC in IM), D-methionine transport system permease MetI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.111 | TMH | 0 | 18.923 | - | 5 | 5 | N | o20-40i52-76o82-105i142-162o182-203i | CytoplasmicMembrane | 10 | ||||||
| THIP_ECOLI | P31549 | thiP yabK | yabK | b0067 JW0066 | integral IM protein (SEC in IM), Thiamine transport system permease ThiP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.209 | TMH | 0 | 18.9215 | - | 12 | 12 | N | i12-38o58-78i90-114o134-151i199-220o240-260i289-311o331-354i375-394o406-424i465-484o504-525i | CytoplasmicMembrane | 10 | 11 | |||||
| CAIT_ECOLI | P31553 | caiT yaaP | yaaP | b0040 JW0039 | integral IM protein (SEC-YidC in IM), L-carnitine/gamma-butyrobetaine antiporter CaiT | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 36 | 0.144 | TMH | 0 | 16.018 | - | 12 | 12 | N | i12-30o50-71i91-116o145-163i195-216o228-251i263-286o318-335i347-366o406-425i446-466o472-495i | CytoplasmicMembrane | 10 | |||||
| SETA_ECOLI | P31675 | setA yabM | yabM | b0070 JW0069 | integral IM protein (SEC in IM), Sugar efflux transporter A SetA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.202 | TMH | 0 | 15.307 | - | 12 | 11 | Y | n13-24c32/33o48-70i82-99o105-127i148-166o172-196i217-236o256-275i282-301o307-329i341-363o369-387i | CytoplasmicMembrane | 10 | ||||||
| YAAU_ECOLI | P31679 | yaaU yabE | yabE | b0045 JW0044 | integral IM protein (SEC in IM), Putative metabolite transport YaaU | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.102 | TMH | 0 | 7.08001 | - | 12 | 12 | N | i20-42o54-74i86-104o110-132i144-166o172-193i242-263o283-303i310-329o335-358i370-390o402-421i | CytoplasmicMembrane | 10 | ||||||
| DJLA_ECOLI | P31680 | djlA yabH | yabH | b0055 JW0054 | integral IM protein (SEC in IM), Co-chaperone DjlA | Integral Inner Membrane | PMID: 11106641 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 22 | 0.135 | TMH | 0 | 10.4559 | - | 1 | 1 | N | o6-30i | CytoplasmicMembrane | 10 | 11 | |||||
| CHAA_ECOLI | P31801 | chaA | b1216 JW1207 | integral IM protein (SEC in IM), Sodium-potassium/proton antiporter ChaA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 62 | 0.229 | TMH | 0 | 1.59472 | - | 11 | 11 | N | i15-32o38-60i72-94o106-131i143-164o170-188i221-240o252-269i290-313o319-340i347-365o | CytoplasmicMembrane | 10 | |||||||
| YDDA_ECOLI | P31826 | yddA | b1496 JW5242 | integral IM protein (SEC in IM), ABC transporter ATP-binding YddA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.12 | CYT | 0 | -0.200913 | - | 5 | 5 | N | o6-24i31-51o71-90i152-173o193-210i | CytoplasmicMembrane | 10 | |||||||
| YDCD_ECOLI | P31991 | ydcD | b1457 JW1452 | integral IM protein (SEC in IM), YdcD | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 32 | 0.142 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-25o | Unknown | 2 | 9 | |||||||||
| YIBI_ECOLI | P32108 | yibI | b3598 JW3572 | integral IM protein (SEC in IM), YibI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.12 | TMH | 0 | 12.0249 | - | 2 | 2 | N | o6-25i46-66o | CytoplasmicMembrane | 10 | 33 | |||||||
| YIHF_ECOLI | P32128 | yihF | b3861 JW5574 | integral IM protein (SEC in IM), YihF | Integral Inner Membrane | Potential Signal Peptide. It appears to have aminotemrinal TM. It is homologous to YDGA_ECOLI. | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | no | yes | N | 25 | 0.128 | SpI | 23 | 2.38596 | - | 1 | 0 | Y | n5-13c18/19o | CytoplasmicMembrane | 9 | 82 | |||||||
| YIHG_ECOLI | P32129 | yihG | b3862 JW3834 | integral IM protein (SEC in IM), Probable acyltransferase YihG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | N/A | Cell inner membrane; Multi-pass membrane protein | Cytoplasmic | SRP | SEC | no | yes | N | 41 | 0.134 | TMH | 0 | 9.85797 | - | 1 | 3 | N | o14-47i59-77o97-116i | CytoplasmicMembrane | 10 | 15 | ||||||
| YIHN_ECOLI | P32135 | yihN | b3874 JW3845 | integral IM protein (SEC in IM), YihN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Membrane Lipoprotein | SRP | SEC | no | yes | N | 23 | 0.116 | SpII | 15 | 5.95413 | Pos+2=G | 12 | 11 | Y | n7-17c22/23o46-67i74-90o96-122i143-165o171-189i221-242o248-268i289-308o314-339i351-374o386-406i | CytoplasmicMembrane | 10 | |||||||
| YIHO_ECOLI | P32136 | yihO | b3876 JW5852 | integral IM protein (SEC in IM), Putative sulfoquinovose importer YihO | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.104 | TMH | 0 | 5.69819 | - | 11 | 12 | N | i17-38o50-74i86-106o118-139i160-179o185-206i238-258o270-291i303-322o328-350i381-402o414-436i | CytoplasmicMembrane | 10 | |||||||||
| YIHP_ECOLI | P32137 | yihP | b3877 JW3848 | integral IM protein (SEC in IM), Putative 2,3-dihydroxypropane-1-sulfonate exporter YihP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 68 | 0.101 | CYT | 0 | -0.200913 | - | 11 | 11 | N | i20-41o53-77i89-109o121-143i164-183o189-210i244-264o276-297i309-328o334-356i421-442o | CytoplasmicMembrane | 10 | |||||||
| PTFLB_ECOLI | P32154 | frvB yiiJ | yiiJ | b3899 JW5562 | integral IM protein (SEC in IM), Fructose-like PTS system EIIBC component FrvB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.166 | CYT | 0 | -0.200913 | - | 9 | 10 | N | i139-159o179-198i205-222o228-247i259-281o301-321i342-363o375-396i403-422o442-463i | CytoplasmicMembrane | 10 | ||||||
| MENA_ECOLI | P32166 | menA yiiW | yiiW | b3930 JW3901 | integral IM protein (SEC in IM), 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 36 | 0.309 | TMH | 0 | 4.61773 | - | 9 | 9 | N | i21-38o44-63i98-118o124-143i150-172o178-199i228-246o252-270i290-307o | CytoplasmicMembrane | 10 | 14 | |||||
| PTFC2_ECOLI | P32672 | frwC yijJ | yijJ | b3949 JW3921 | integral IM protein (SEC in IM), Fructose-like permease IIC component 2 FrwC | Integral Inner Membrane | Multiphosphoryl transfer protein 2 | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.192 | TMH | 0 | 4.57594 | - | 8 | 9 | N | o22-45i57-78o98-120i132-152o172-190i202-229o249-269i281-301o313-334i | CytoplasmicMembrane | 10 | |||||
| PSPG_ECOLI | P32696 | pspG yjbO | yjbO | b4050 JW5716 | integral IM protein (SEC in IM), Phage shock G PspG | Integral Inner Membrane | PMID: 19555453 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | Prophage Transposase | no | no | N | 32 | 0.133 | TMH | 0 | 16.1628 | - | 2 | 2 | N | i7-37o43-64i | CytoplasmicMembrane | 9 | |||||
| YJCB_ECOLI | P32700 | yjcB | b4060 JW5718 | integral IM protein (SEC in IM), YjcB | Integral Inner Membrane | PMID: 19555453 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 65 | 0.12 | TMH | 0 | 9.92398 | - | 2 | 2 | N | o12-29i36-56o | CytoplasmicMembrane | 9 | 45 | |||||||
| PDEC_ECOLI | P32701 | pdeC yjcC | yjcC | b4061 JW4022 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 35 | 0.165 | TMH | 0 | 3.89399 | - | 2 | 2 | N | i12-34o243-264i | CytoplasmicMembrane | 10 | ||||||
| YJCE_ECOLI | P32703 | yjcE | b4065 JW4026 | integral IM protein (SEC in IM), YjcE | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 69 | 0.131 | TMH | 0 | 7.97851 | - | 11 | 13 | N | o6-25i32-50o56-73i85-108o114-136i157-179o185-204i216-235o241-259i280-298o313-337i361-385o397-420i | CytoplasmicMembrane | 10 | |||||||||
| ACTP_ECOLI | P32705 | actP yjcG | yjcG | b4067 JW4028 | integral IM protein (SEC in IM), Cation/acetate symporter ActP | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | Y | 19 | 0.597 | SpI | 18 | 16.2988 | - | 13 | 13 | Y | n4-14c18/19o34-54i75-97o103-122i148-167o179-197i209-227o262-286i298-323o355-383i404-423o429-453i465-486o498-517i | CytoplasmicMembrane | 10 | ||||||
| NRFD_ECOLI | P32709 | nrfD yjcK | yjcK | b4073 JW4034 | integral IM protein (SEC in IM), NrfD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.148 | TMH | 0 | 10.9164 | - | 8 | 8 | N | o18-39i51-73o93-113i150-168o180-203i224-241o261-278i290-312o | CytoplasmicMembrane | 10 | ||||||
| NRFE_ECOLI | P32710 | nrfE yjcL | yjcL | b4074 JW4035 | integral IM protein (SEC in IM), Probable cytochrome c-type biogenesis NrfE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 10 | 0.193 | TMH | 0 | 7.53708 | - | 12 | 12 | N | i21-54o79-97i104-126o158-178i190-212o232-248i260-288o294-312i333-357o377-394i401-422o528-545i | CytoplasmicMembrane | 10 | ||||||
| NRFF_ECOLI | P32711 | nrfF yjcM | yjcM | b4075 JW4036 | integral IM protein (SEC in IM), Formate-dependent nitrite reductase complex subunit NrfF | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Periplasm | Membrane anchored | SRP | SEC | no | yes | Y | 19 | 0.845 | SpI | 18 | 16.61 | - | 1 | 1 | Y | n4-14c18/19o103-121i | CytoplasmicMembrane | 10 | 20 | |||||||
| MDTO_ECOLI | P32715 | mdtO yjcQ | yjcQ | b4081 JW4042 | integral IM protein (SEC in IM), Multidrug resistance MdtO | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.102 | CYT | 0 | -0.200913 | - | 9 | 9 | N | o36-63i75-97o103-120i127-146o152-178i399-420o426-445i457-477o483-502i | CytoplasmicMembrane | 10 | ||||||||
| MDTN_ECOLI | P32716 | mdtN yjcR | yjcR | b4082 JW4043 | integral IM protein (SEC in IM), Multidrug resistance MdtN | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 47 | 0.139 | SpI | 35 | 7.86193 | - | 1 | 0 | Y | n15-30c35/36o | CytoplasmicMembrane | 9 | ||||||||
| ALSC_ECOLI | P32720 | alsC yjcV | yjcV | b4086 JW4047 | integral IM protein (SEC-YidC in IM), D-allose transport system permease AlsC | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | N | 49 | 0.11 | TMH | 0 | 4.98579 | - | 9 | 8 | N | i21-42o71-93i105-129o168-193i222-246o252-272i279-298o304-324i | CytoplasmicMembrane | 10 | |||||
| YEEA_ECOLI | P33011 | yeeA | b2008 JW1990 | integral IM protein (SEC in IM), YeeA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.114 | TMH | 0 | 6.9225 | - | 5 | 6 | N | i20-40o46-66i73-89o95-113i120-136o148-168i | CytoplasmicMembrane | 10 | 32 | ||||||
| YEEE_ECOLI | P33015 | yeeE | b2013 JW1995 | integral IM protein (SEC in IM), UPF0394 YeeE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 59 | 0.121 | TMH | 0 | 4.74224 | - | 9 | 9 | Y | n6-17c25/26o41-60i72-100o106-123i144-169o198-217i224-241o247-266i287-310o316-337i | CytoplasmicMembrane | 10 | |||||||
| NUPX_ECOLI | P33021 | nupX yeiJ | yeiJ | b2161 JW2148 | integral IM protein (SEC in IM), Putative nucleoside permease NupX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein(experimental) | SRP | SEC | yes | yes | N | 57 | 0.114 | TMH | 0 | 3.09344 | - | 8 | 10 | N | o6-22i29-49o61-82i89-108o114-132i173-195o201-220i258-280o353-380i392-415o | CytoplasmicMembrane | 10 | ||||||
| PSUT_ECOLI | P33024 | psuT pscT yeiM | pscT yeiM | b2164 JW2151 | integral IM protein (SEC in IM), Putative pseudouridine transporter PsuT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 25 | 0.143 | TMH | 0 | 2.44494 | - | 8 | 10 | N | o6-22i29-49o95-118i173-195o201-220i258-280o286-310i322-341o353-378i390-413o | CytoplasmicMembrane | 10 | ||||||
| SETB_ECOLI | P33026 | setB yeiO | yeiO | b2170 JW2157 | integral IM protein (SEC in IM), Sugar efflux transporter B SetB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.175 | TMH | 0 | 8.14886 | - | 12 | 12 | N | i12-33o53-72i84-101o107-129i141-158o164-194i219-244o256-276i283-301o307-330i351-367o373-390i | CytoplasmicMembrane | 10 | ||||||
| FLIR_ECOLI | P33135 | fliR flaP | flaP | b1950 JW1934 | Flagellar integral IM protein (SEC in IM), biosynthetic FliR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | flagellum | SRP | SEC | no | yes | N | 61 | 0.121 | TMH | 0 | 5.44162 | - | 6 | 6 | N | o15-33i42-59o65-86i131-151o179-201i213-237o | CytoplasmicMembrane | 10 | |||||
| YEBE_ECOLI | P33218 | yebE | b1846 JW1835 | integral IM protein (SEC in IM), YebE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | N/A | Cell inner membrane; Single-pass membrane protein | Membrane anchored | SRP | SEC | no | yes | N | 24 | 0.329 | SpI | 23 | 0.790424 | - | 2 | 2 | N | o26-44i56-74o | CytoplasmicMembrane | 10 | 88 | ||||||
| TORC_ECOLI | P33226 | torC | b0996 JW0981 | integral IM protein (SEC in IM), Cytochrome c-type TorC | Integral Inner Membrane | TAT secretion system. Binds 5 heme groups per subunit ; Belongs to the torC/torY family. Trimethylamine N-oxide (TMAO) respiration system is encoded by the torCAD operon and comprises a periplasmic TMAO reductase (TorA) and a c-type cytochrome (TorC), which shuttles electrons to TorA. The immature C-terminal domain of TorC strongly down-regulated the tor operon and interacted with the TorS detector region. Electron transfer and binding of the c-type cytochrome TorC to the trimethylamine N-oxide reductase PMID: 11056172 | PMID: 11056172 PMID: 11562502 PMID: 17218314 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane; Single-pass type II membrane protein | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 20 | 0.12 | TMH | 0 | 6.50112 | - | 1 | 1 | N | i12-34o | CytoplasmicMembrane | 9 | 43 | |||||
| LLDP_ECOLI | P33231 | lldP lctP | lctP | b3603 JW3578 | integral IM protein (SEC in IM), L-lactate permease LldP | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. | PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 66 | 0.171 | TMH | 0 | 11.5559 | - | 12 | 12 | N | o12-33i40-58o70-95i116-149o155-179i199-217o223-240i252-269o368-387i407-425o431-456i529-550o | CytoplasmicMembrane | 10 | |||||
| MOKC_ECOLI | P33236 | mokC gefL | gefL | b0018 JW5879 | integral IM protein (SEC in IM), Regulatory MokC | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Periplasmic | SRP | SEC | no | yes | N | 41 | 0.287 | SpI | 40 | 1.37208 | - | 1 | 1 | N | i25-44o | Periplasmic | 9 | ||||||||
| YEHW_ECOLI | P33359 | yehW | b2128 JW2116 | integral IM protein (SEC in IM), Glycine betaine uptake system permease YehW | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.403 | TMH | 0 | 15.5124 | - | 6 | 5 | Y | n8-22c30/31o46-74i86-111o117-144i164-189o201-226i | CytoplasmicMembrane | 10 | 15 | ||||||
| YEHY_ECOLI | P33361 | yehY | b2130 JW2118 | integral IM protein (SEC in IM), Glycine betaine uptake system permease YehY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.257 | TMH | 0 | 13.4216 | - | 10 | 9 | Y | n9-16c20/21o44-65i72-90o102-123i135-153o183-204i225-246o258-278i324-347o353-379i | CytoplasmicMembrane | 10 | |||||||
| YOHD_ECOLI | P33366 | yohD | b2136 JW2124 | integral IM protein (SEC in IM) of DedA family, YohD | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 22 | 0.131 | CYT | 0 | -0.200913 | - | 4 | 4 | N | i12-35o41-63i122-143o163-180i | CytoplasmicMembrane | 10 | 65 | |||||
| NIKB_ECOLI | P33591 | nikB | b3477 JW3442 | integral IM protein (SEC in IM), Nickel transport system permease NikB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.197 | TMH | 0 | 11.5427 | - | 6 | 6 | N | i9-29o104-125i137-164o176-195i232-255o275-298i | CytoplasmicMembrane | 10 | |||||||
| NUOL_ECOLI | P33607 | nuoL | b2278 JW2273 | integral IM protein (SEC in IM), NADH-quinone oxidoreductase subunit L NuoL | Integral Inner Membrane | PMID: 15919996 PMID: 20732298 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 27 | 0.186 | TMH | 0 | 9.92034 | - | 16 | 17 | Y | n4-15c19/20o29-52i64-81o87-104i116-133o139-158i170-189o209-228i249-267o279-300i307-325o331-354i374-392o412-434i455-475o495-513i534-560o593-612i | CytoplasmicMembrane | 10 | |||||||
| FEOB_ECOLI | P33650 | feoB | b3409 JW3372 | integral IM protein (SEC in IM), FeoB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.107 | CYT | 0 | -0.200913 | - | 10 | 9 | N | o282-302i309-327o347-367i421-447o453-473i511-529o664-685i697-715o721-742i | CytoplasmicMembrane | 10 | 8 | ||||||
| YBBD_ECOLI | P33669 | ybbD | b0501 JW0489 | integral IM protein (SEC in IM), Putative YbbD | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Membrane | Membrane anchored | SRP | SEC | pseudogene (Uniprot) | no | no | N | 35 | 0.114 | TMH | 0 | 9.05171 | - | 1 | 1 | N | o12-32i | CytoplasmicMembrane | 9 | 46 | |||||||
| YEJE_ECOLI | P33915 | yejE | b2179 JW2167 | integral IM protein (SEC in IM), ABC transporter permease YejE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 43 | 0.206 | TMH | 0 | 6.40686 | - | 6 | 6 | N | i21-42o142-167i179-197o203-222i259-286o306-327i | CytoplasmicMembrane | 10 | |||||||
| CCMF_ECOLI | P33927 | ccmF yejR | yejR | b2196 JW2184 | integral IM protein (SEC in IM), Cytochrome c-type biogenesis CcmF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 54 | 0.151 | TMH | 0 | 12.9934 | - | 15 | 15 | N | o6-29i41-62o96-114i121-142o178-198i210-230o250-267i274-294o314-332i353-374o394-412i424-444o450-472i484-503o609-629i | CytoplasmicMembrane | 10 | ||||||
| NAPH_ECOLI | P33934 | napH yejZ | yejZ | b2204 JW2192 | integral IM protein (SEC in IM), Ferredoxin-type NapH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.13 | TMH | 0 | 7.44595 | - | 4 | 4 | N | i30-50o78-98i139-160o172-192i | CytoplasmicMembrane | 10 | 6 | |||||
| YOJI_ECOLI | P33941 | yojI yojJ | yojJ | b2211 JW2199 | integral IM protein (SEC in IM), ABC transporter ATP-binding/permease YojI | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.136 | TMH | 0 | 12.5457 | - | 6 | 6 | N | i12-36o56-80i125-144o150-169i231-253o273-296i | CytoplasmicMembrane | 10 | 18 | |||||||
| MDTD_ECOLI | P36554 | mdtD yegB | yegB | b2077 JW2062 | integral IM protein (SEC in IM), Putative multidrug resistance MdtD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.206 | TMH | 0 | 7.65965 | - | 13 | 13 | N | i12-33o45-64i76-96o102-123i135-157o163-185i197-214o226-243i263-280o286-308i329-355o396-418i430-451o | CytoplasmicMembrane | 10 | ||||||
| COBS_ECOLI | P36561 | cobS | b1992 JW1970 | integral IM protein (SEC in IM), Adenosylcobinamide-GDP ribazoletransferase CobS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 58 | 0.15 | TMH | 0 | 3.98364 | - | 4 | 6 | N | i34-58o64-88i109-132o138-158i178-196o202-219i | CytoplasmicMembrane | 10 | 2 | ||||||
| HOFC_ECOLI | P36646 | hofC hopC yacD | hopC yacD | b0106 JW0102 | integral IM protein (SEC in IM), transport homolog HofC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 19 | 0.132 | CYT | 0 | -0.200913 | - | 3 | 4 | N | i162-185o216-234i263-281o369-389i | CytoplasmicMembrane | 10 | ||||||
| PPDD_ECOLI | P36647 | ppdD | b0108 JW0104 | integral IM protein (SEC in IM), Prepilin peptidase-dependent D PpdD | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Fimbrium | Membrane anchored | SRP | SEC | no | yes | N | 53 | 0.143 | TMH | 0 | 4.07217 | - | 1 | 1 | N | i12-30o | Extracellular | 9 | 9 | ||||||||
| DSBD_ECOLI | P36655 | dsbD cutA2 cycZ dipZ | cutA2 cycZ dipZ | b4136 JW5734 | integral IM protein (SEC in IM), Thiol:disulfide interchange DsbD | Integral Inner Membrane | DsbD is an inner membrane protein that is recognised and targeted to the Sec pathway by short, cleavable, N-terminal signal sequence. PMID: 15919996 Disulfide bridge (122 128;182 304;480 483) | PMID: 15919996 PMID: 18406599 PMID: 7628442 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | Y | 20 | 0.853 | SpI | 19 | 10.1575 | - | 8 | 7 | Y | n5-13c19/20o168-195i207-231o243-267i288-317o329-351i363-381o387-406i | CytoplasmicMembrane | 10 | |||||
| PTTBC_ECOLI | P36672 | treB | b4240 JW4199 | integral IM protein (SEC in IM), PTS system trehalose-specific EIIBC component TreB | Integral Inner Membrane | Trigger factor-sensitive aggregation. | PMID: 15919657 PMID: 15919996 PMID: 19737520 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP,TF | SEC | no | yes | N | 44 | 0.348 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i107-131o159-180i187-208o228-245i257-281o301-321i341-361o373-392i399-418o438-461i | CytoplasmicMembrane | 10 | 4 | |||||
| GSPM_ECOLI | P36678 | gspM hopZ pshM | hopZ pshM | b3334 JW5704 | integral IM protein (SEC in IM), Putative type II secretion system M GspM | Integral Inner Membrane | Potential component of type II secretion system. | PMID: 11118204 PMID: 14966662 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 30 | 0.121 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o16-34i | Unknown | 2 | |||||
| DTPB_ECOLI | P36837 | dtpB yhiP | yhiP | b3496 JW3463 | integral IM protein (SEC in IM), Dipeptide and tripeptide permease B DtpB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 61 | 0.154 | TMH | 0 | 6.34727 | - | 14 | 14 | N | i28-46o52-72i84-101o107-124i145-167o173-193i214-232o238-256i268-285o320-337i349-371o383-408i415-437o457-479i | CytoplasmicMembrane | 10 | ||||||
| RSMB_ECOLI | P36929 | rsmB fmu/fmv rrmB sun yhdB | fmu/fmv rrmB sun yhdB | b3289 JW3250 | integral IM protein (SEC in IM), Ribosomal RNA small subunit methyltransferase B RsmB | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cytoplasm | Cytoplasmic | SRP | SEC | yes | yes | N | 68 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i76-93o | Cytoplasmic | 9 | 50 | |||||||
| CRCB_ECOLI | P37002 | crcB ybeI | ybeI | b0624 JW0619 | integral IM protein (SEC-YidC in IM), Putative fluoride ion transporter CrcB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. Dual topology membrane protein: can insert into the membrane in both directions. PMID: 15919996 | PMID: 15919996 PMID: 16429150 PMID: 22108384 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | in/out, out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | yes | yes | N | 33 | 0.138 | TMH | 0 | 7.1142 | - | 4 | 3 | Y | n2-10c15/16o31-55i67-91o97-121i | CytoplasmicMembrane | 10 | 19 | ||||
| CLCA_ECOLI | P37019 | clcA eriC yadQ | eriC yadQ | b0155 JW5012 | integral IM protein (SEC in IM), H(+)/Cl(-) exchange transporter ClcA | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertionPMID: 9008159. Alpha-helcal transmembrane protein (experimental). The transmembrane segments are all helical and buried within the protein and the membranePMID: 11796999. C-terminal tagging with the alkaline phosphatase and green fluorescent protein in order to define the periplasmic or cytoplasmic locations of the C terminiPMID: 15919996. | PMID: 11266632 PMID: 11796999 PMID: 15919996 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 50 | 0.115 | CYT | 0 | -0.200913 | - | 11 | 10 | N | o33-53i74-97o177-201i213-232o252-270i291-308o328-348i355-376o388-413i420-439o | CytoplasmicMembrane | 10 | 38 | ||||
| RIR4_ECOLI | P37146 | nrdF ygaD | ygaD | b2676 JW2651 | integral IM protein (SEC in IM), Ribonucleoside-diphosphate reductase 2 subunit beta NrdF | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cytoplasmic | SRP | SEC | yes | yes | N | 62 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i152-172o | Unknown | 2 | 31 | ||||||||
| FXSA_ECOLI | P37147 | fxsA yjeG | yjeG | b4140 JW4100 | integral IM protein (SEC in IM), UPF0716 FxsA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 64 | 0.114 | TMH | 0 | 5.51241 | - | 3 | 3 | N | o6-24i29-47o78-101i | CytoplasmicMembrane | 10 | 25 | |||||
| HYBB_ECOLI | P37180 | hybB | b2995 JW5494 | integral IM protein (SEC in IM), Probable Ni/Fe-hydrogenase 2 b-type cytochrome subunit HybB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 69 | 0.111 | TMH | 0 | 13.5768 | - | 10 | 10 | N | i12-31o51-79i91-110o130-154i166-184o211-234i246-264o284-302i314-332o352-373i | CytoplasmicMembrane | 10 | |||||||
| HOKA_ECOLI | P37305 | hokA yiaZ | yiaZ | b4455 JW3526 | integral IM protein (SEC in IM), HokA | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 25 | 0.11 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-24o | Periplasmic | 9 | 110 | ||||
| YFDC_ECOLI | P37327 | yfdC | b2347 JW2344 | integral IM protein (SEC in IM), YfdC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.112 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i58-76o96-114i135-158o187-206i213-233o253-275i | CytoplasmicMembrane | 10 | 38 | ||||||
| MDTK_ECOLI | P37340 | mdtK norE norM ydhE | norE norM ydhE | b1663 JW1655 | integral IM protein (SEC in IM), Multidrug resistance MdtK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 37 | 0.255 | TMH | 0 | 9.01951 | - | 12 | 11 | Y | n10-21c29/30o53-72i92-113o133-149i161-183o189-212i245-268o280-301i313-336o348-366i387-407o419-438i | CytoplasmicMembrane | 10 | ||||||
| YCAI_ECOLI | P37443 | ycaI | b0913 JW5120 | integral IM protein (SEC in IM), YcaI | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.135 | TMH | 0 | 10.6181 | - | 7 | 12 | N | o23-42i49-69o222-243i255-274o280-297i304-322o328-346i358-383o389-411i423-439o445-467i474-491o | CytoplasmicMembrane | 10 | |||||||||
| YDHC_ECOLI | P37597 | ydhC | b1660 JW1652 | integral IM protein (SEC in IM), transport YdhC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.384 | TMH | 0 | 10.7821 | - | 12 | 11 | Y | n7-22c30/31o40-61i73-91o97-119i131-155o161-180i209-229o235-258i270-293o299-322i334-355o361-381i | CytoplasmicMembrane | 10 | |||||||
| YHHL_ECOLI | P37614 | yhhL | b3466 JW5683 | integral IM protein (SEC in IM), YhhL | Integral Inner Membrane | B | Binout | out/out | IM (predicted) | Integral Membrane Protein | SRP | SEC | no | yes | N | 25 | 0.114 | TMH | 0 | 1.98334 | - | 2 | 1 | Y | n8-19c24/25o34-51i | CytoplasmicMembrane | 9 | 47 | |||||||||
| YHHM_ECOLI | P37615 | yhhM | b3467 JW3432 | integral IM protein (SEC in IM), YhhM | Single transmembrane helice predicted which would be removed upon signal peptide cleavage IM-cter inside. | Integral Inner Membrane | B | Bin | out/in | N/A | Membrane anchored | SRP | SEC | yes | yes | N | 32 | 0.135 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-24i | Unknown | 2 | 75 | ||||||||
| ZNTA_ECOLI | P37617 | zntA yhhO | yhhO | b3469 JW3434 | integral IM protein (SEC in IM), Zinc/cadmium/lead-transporting P-type ATPase ZntA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.185 | CYT | 0 | -0.200913 | - | 5 | 8 | N | i128-144o150-168i180-197o203-222i353-374o380-404i686-702o708-729i | CytoplasmicMembrane | 10 | 26 | |||||
| QPTR_ECOLI | P37619 | yhhQ | b3471 JW3436 | integral IM protein (SEC in IM), Queuosine precursor transporter YhhQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.133 | TMH | 0 | 11.3075 | - | 6 | 6 | N | i12-31o43-64i71-92o104-127i139-165o185-206i | CytoplasmicMembrane | 10 | |||||||
| YHHS_ECOLI | P37621 | yhhS | b3473 JW5945 | integral IM protein (SEC in IM), MFS-type transporter YhhS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.135 | TMH | 0 | 8.30657 | - | 12 | 12 | N | i19-41o47-65i85-103o109-131i152-175o181-199i220-241o253-271i283-303o309-330i342-364o370-388i | CytoplasmicMembrane | 10 | |||||||
| RBBA_ECOLI | P37624 | rbbA yhiG yhiH | yhiG yhiH | b3486 JW5676 | integral IM protein (SEC in IM), Ribosome-associated ATPase RbbA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 24 | 0.13 | CYT | 0 | -0.200913 | - | 5 | 6 | N | i558-579o716-739i766-789o795-817i824-845o884-906i | CytoplasmicMembrane | 10 | 17 | |||||
| YHII_ECOLI | P37626 | yhiI | b3487 JW3454 | integral IM protein (SEC in IM), YhiI | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Membrane anchored | SRP | SEC | no | yes | N | 31 | 0.132 | TMH | 0 | 4.13485 | - | 1 | 1 | N | i7-27o | CytoplasmicMembrane | 7 | ||||||||||
| YHIM_ECOLI | P37630 | yhiM | b3491 JW5944 | integral IM protein (SEC in IM), YhiM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.131 | TMH | 0 | 11.4226 | - | 10 | 10 | N | i7-28o40-62i74-95o107-133i154-175o187-211i223-246o258-281i293-313o325-343i | CytoplasmicMembrane | 10 | |||||||
| YHIN_ECOLI | P37631 | yhiN | b3492 JW3459 | integral IM protein (SEC in IM), YhiN | Integral Inner Membrane | B | Bout | in/out | N/A | Cytoplasmic | SRP | SEC | yes | yes | N | 23 | 0.367 | SpI | 22 | 3.94669 | - | 1 | 0 | Y | n6-17c22/23o | Unknown | 4 | 20 | |||||||||
| MDTF_ECOLI | P37637 | mdtF yhiV | yhiV | b3514 JW3482 | integral IM protein (SEC in IM), Multidrug resistance MdtF | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 55 | 0.14 | TMH | 0 | 7.6049 | - | 11 | 12 | N | i12-32o340-359i366-390o396-416i437-458o470-497i539-555o873-890i897-917o923-948i969-989o1009-1031i | CytoplasmicMembrane | 10 | ||||||
| YHJD_ECOLI | P37642 | yhjD | b3522 JW3490 | integral IM protein (SEC in IM), YhjD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.105 | CYT | 0 | -0.200913 | - | 6 | 5 | N | o72-97i186-209o229-250i262-282o294-321i | CytoplasmicMembrane | 10 | 13 | ||||||
| YHJE_ECOLI | P37643 | yhjE | b3523 JW3491 | integral IM protein (SEC in IM), metabolite transport YhjE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 45 | 0.121 | CYT | 0 | -0.200913 | - | 11 | 11 | N | o38-54i66-85o97-130i168-188o200-217i249-270o290-312i321-340o346-370i382-403o409-431i | CytoplasmicMembrane | 10 | |||||||
| YHJG_ECOLI | P37645 | yhjG yhjF | yhjF | b3524 JW3492 | integral IM protein (SEC in IM), YhjG | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | yes | yes | N | 33 | 0.12 | TMH | 0 | 1.70796 | - | 1 | 1 | N | i7-29o | Unknown | 2 | 10 | |||||||
| PDEK_ECOLI | P37649 | pdeK yhjK | yhjK | b3529 JW5943 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.106 | TMH | 0 | 5.39989 | - | 2 | 2 | N | o12-35i151-176o | CytoplasmicMembrane | 10 | ||||||
| BCSB_ECOLI | P37652 | bcsB yhjN | yhjN | b3532 JW3500 | integral IM protein (SEC-YidC in IM), Cyclic di-GMP-binding BcsB | Integral Inner Membrane | BscC is involved in biosynthesis of cellulose, which is a significant constituent of the extracellular matrix. Encodes the catalytic subunit of cellulose synthase. Exhibites aberrant localization by microscopy in the absence of YidC. BcsA and BcsB form the catalytically active core of bacterial cellulose synthase sufficient for in vitro cellulose synthesis. 24127606 Cellulose filaments have been visualized in situ via scanning electron and fluorescence microscopy. PMID: 24097954 | 24127606 PMID: 15919996 PMID: 2030672 PMID: 22108384 PMID: 24097954 | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cell inner membrane; Single-pass type I membrane protein | Integral Membrane Protein | SRP | SEC-YidC | no | yes | Y | 26 | 0.342 | SpI | 25 | 20.4203 | - | 2 | 1 | Y | n5-13c25/26o745-766i | CytoplasmicMembrane | 10 | 82 | ||||
| BCSA_ECOLI | P37653 | bcsA yhjO yhjP | yhjO yhjP | b3533 JW5665 | integral IM protein (SEC in IM), Cellulose synthase catalytic subunit BcsA | Integral Inner Membrane | BcsA and BcsB form the catalytically active core of bacterial cellulose synthase sufficient for in vitro cellulose synthesis. 24127606 Cellulose filaments have been visualized in situ via scanning electron and fluorescence microscopy. PMID: 24097954 | 24127606 PMID: 24097954 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 16 | 0.123 | CYT | 0 | -0.200913 | - | 10 | 9 | Y | n3-10c15/16o31-50i150-168o174-190i197-216o228-252i524-547o553-575i639-659o665-690i | CytoplasmicMembrane | 10 | |||||
| BCSG_ECOLI | P37659 | bcsG yhjU | yhjU | b3538 JW3506 | integral IM protein (SEC in IM), Cellulose biosynthesis BcsG | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 52 | 0.108 | TMH | 0 | 9.60827 | - | 4 | 4 | N | o34-56i68-85o113-132i139-162o | CytoplasmicMembrane | 10 | 10 | |||||||
| YHJV_ECOLI | P37660 | yhjV | b3539 JW3508 | integral IM protein (SEC in IM), transport YhjV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 34 | 0.111 | TMH | 0 | 10.9997 | - | 11 | 11 | N | i20-40o46-64i95-118o138-155i167-185o205-227i247-267o294-318i339-362o368-389i401-422o | CytoplasmicMembrane | 10 | |||||||
| EPTB_ECOLI | P37661 | eptB yhjW | yhjW | b3546 JW5660 | integral IM protein (SEC in IM), EptB | Integral Inner Membrane | Disulfide bond-containing protein PMID: 25664544 | PMID: 15795227 PMID: 15919996 PMID: 25664544 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 38 | 0.136 | TMH | 0 | 11.408 | - | 5 | 5 | N | i12-30o42-65i77-103o123-140i161-178o | CytoplasmicMembrane | 10 | |||||
| YHJX_ECOLI | P37662 | yhjX | b3547 JW3516 | integral IM protein (SEC in IM), MFS-type transporter YhjX | Integral Inner Membrane | PMID: 15919996 PMID: 23222720 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.124 | TMH | 0 | 10.8343 | - | 12 | 12 | N | i12-33o45-66i78-95o101-122i134-154o166-186i216-237o249-270i282-301o307-329i341-360o366-387i | CytoplasmicMembrane | 10 | |||||||
| WECH_ECOLI | P37669 | wecH yiaH | yiaH | b3561 JW3533 | integral IM protein (SEC in IM), O-acetyltransferase WecH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 33 | 0.129 | TMH | 0 | 7.27964 | - | 10 | 10 | N | i12-29o49-67i79-102o114-131i143-160o172-190i202-224o236-255i267-288o300-321i | CytoplasmicMembrane | 10 | ||||||
| YIAM_ECOLI | P37674 | yiaM | b3577 JW3549 | integral IM protein (SEC in IM), 2,3-diketo-L-gulonate TRAP transporter small permease YiaM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 23 | 0.132 | TMH | 0 | 6.97669 | - | 4 | 4 | N | i7-28o40-59i80-101o113-137i | CytoplasmicMembrane | 10 | 13 | ||||||
| YIAN_ECOLI | P37675 | yiaN | b3578 JW5651 | integral IM protein (SEC in IM), 2,3-diketo-L-gulonate TRAP transporter large permease YiaN | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 66 | 0.188 | TMH | 0 | 16.4337 | - | 11 | 11 | N | o12-35i56-75o95-124i136-158o170-191i212-234o240-256i277-295o315-343i355-375o395-419i | CytoplasmicMembrane | 10 | |||||||||
| YIAV_ECOLI | P37683 | yiaV | b3586 JW3558 | integral IM protein (SEC in IM), YiaV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 16 | 0.116 | TMH | 0 | 1.11111 | - | 2 | 1 | Y | n3-13c17/18o27-49i | CytoplasmicMembrane | 10 | 22 | ||||||
| RFBX_ECOLI | P37746 | rfbX wzx | wzx | b2037 JW2022 | integral IM protein (SEC in IM), Putative O-antigen transporter RfbX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 51 | 0.11 | TMH | 0 | 8.627 | - | 10 | 12 | N | i12-30o42-63i84-106o118-139i146-166o172-196i217-243o263-282i294-316o328-349i361-380o386-407i | CytoplasmicMembrane | 10 | ||||||
| RFC_ECOLI | P37748 | rfc yefF | yefF | b2035 JW2020 | integral IM protein (SEC in IM), O-antigen polymerase Rfc | Integral Inner Membrane | Phobius prediction for a very very weak aminoterminal TM | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 50 | 0.134 | TMH | 0 | 0.878412 | - | 12 | 12 | N | i23-43o55-78i99-117o144-161i173-188o194-209i214-233o239-258i270-289o309-332i339-357o363-382i | CytoplasmicMembrane | 10 | |||||
| NARU_ECOLI | P37758 | narU yddF | yddF | b1469 JW1464 | integral IM protein (SEC in IM), Nitrate/nitrite transporter NarU | Integral Inner Membrane | PMID: 15919996 PMID: 18691156 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.118 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i36-60o72-90i102-122o128-150i171-194o214-232i252-276o288-306i318-340o346-374i401-422o434-454i | CytoplasmicMembrane | 10 | ||||||
| YJFF_ECOLI | P37772 | yjfF | b4231 JW5754 | integral IM protein (SEC in IM), ABC transporter permease YjfF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.156 | TMH | 0 | 9.53051 | - | 8 | 8 | N | o6-23i44-77o89-109i116-134o162-180i211-231o251-274i295-315o | CytoplasmicMembrane | 10 | |||||||
| YFJD_ECOLI | P37908 | yfjD ypjE | ypjE | b4461 JW5415 b2612/b2613 | integral IM protein (SEC in IM), UPF0053 YfjD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | no | yes | N | 24 | 0.142 | CYT | 0 | -0.200913 | - | 4 | 4 | N | o6-25i62-86o92-112i124-146o | CytoplasmicMembrane | 10 | 11 | ||||
| CUSA_ECOLI | P38054 | cusA ybdE | ybdE | b0575 JW0564 | integral IM protein (SEC-YidC in IM), Cation efflux system CusA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 39 | 0.202 | TMH | 0 | 6.2187 | - | 12 | 12 | N | i12-32o338-357i364-384o390-411i442-464o484-505i538-554o874-891i898-918o924-948i985-1006o1012-1037i | CytoplasmicMembrane | 10 | |||||
| YDJE_ECOLI | P38055 | ydjE | b1769 JW1758 | integral IM protein (SEC in IM), metabolite transport YdjE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.167 | TMH | 0 | 6.79423 | - | 12 | 12 | N | i21-40o60-80i92-112o118-139i151-173o179-198i264-287o299-320i327-346o352-375i387-410o416-438i | CytoplasmicMembrane | 10 | |||||||
| DGCE_ECOLI | P38097 | dgcE yegE | yegE | b2067 JW2052 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 62 | 0.16 | TMH | 0 | 12.1449 | - | 11 | 10 | N | i12-33o39-58i65-85o91-112i124-144o156-177i189-206o212-228i235-258o270-290i | CytoplasmicMembrane | 10 | ||||||
| EAMB_ECOLI | P38101 | eamB yfiK | yfiK | b2578 JW2562 | integral IM protein (SEC in IM), Cysteine/O-acetylserine efflux protein EamB | Integral Inner Membrane | PMID: 12562784 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 45 | 0.172 | TMH | 0 | 7.57291 | - | 6 | 5 | Y | n4-15c27/28o43-67i74-91o111-133i140-163o175-194i | CytoplasmicMembrane | 10 | ||||||
| ETK_ECOLI | P38134 | etk yccC | yccC | b0981 JW0964 | integral IM protein (SEC in IM), Tyrosine-kinase Etk | Integral Inner Membrane | PMID: 10369665 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein(experimental) | SRP | SEC | no | yes | N | 59 | 0.28 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i33-51o425-445i | CytoplasmicMembrane | 10 | 41 | |||||
| SIEB_ECOLI | P38392 | sieB | b1353 JW5209 | integral IM protein (SEC in IM), Superinfection exclusion B SieB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 42 | 0.105 | TMH | 0 | 3.43476 | - | 2 | 2 | N | i20-38o50-70i | CytoplasmicMembrane | 10 | 13 | |||||
| LPLT_ECOLI | P39196 | lplT ygeD | ygeD | b2835 JW2803 | integral IM protein (SEC in IM), Lysophospholipid transporter LplT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.127 | TMH | 0 | 8.05882 | - | 10 | 11 | N | o20-41i53-73o93-117i138-158o164-184i220-245o257-278i285-302o308-329i349-369o375-393i | CytoplasmicMembrane | 10 | ||||||
| YFCC_ECOLI | P39263 | yfcC | b2298 JW2295 | integral IM protein (SEC in IM), Putative basic amino acid antiporter YfcC | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 49 | 0.144 | TMH | 0 | 3.89092 | - | 11 | 13 | N | i20-41o106-127i148-165o171-187i194-221o233-252i287-308o314-332i353-371o383-403i410-432o452-471i483-503o | CytoplasmicMembrane | 10 | |||||||||
| YJDF_ECOLI | P39270 | yjdF | b4121 JW4082 | integral IM protein (SEC in IM), YjdF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 29 | 0.268 | TMH | 0 | 4.29363 | - | 6 | 6 | N | i7-26o32-49i61-83o103-120i132-155o175-194i | CytoplasmicMembrane | 10 | 3 | ||||||
| DTPC_ECOLI | P39276 | dtpC yjdL | yjdL | b4130 JW4091 | integral IM protein (SEC in IM), Dipeptide and tripeptide permease C DtpC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.104 | TMH | 0 | 2.87637 | - | 14 | 14 | N | i12-35o47-68i75-94o100-116i137-161o167-186i207-228o234-251i263-281o308-329i341-361o373-395i407-428o454-473i | CytoplasmicMembrane | 10 | ||||||
| YJEH_ECOLI | P39277 | yjeH | b4141 JW4101 | integral IM protein (SEC in IM), L-methionine/branched-chain amino acid exporter YjeH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.297 | TMH | 0 | 10.0553 | - | 11 | 10 | Y | n8-21c33/34o43-66i87-108o120-137i149-166o186-208i220-242o262-287i318-336o342-360i372-405o | CytoplasmicMembrane | 10 | |||||||
| YJEM_ECOLI | P39282 | yjeM | b4156 JW5739 | integral IM protein (SEC in IM), transporter YjeM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.324 | TMH | 0 | 13.0295 | - | 12 | 11 | Y | n10-18c23/24o39-62i83-110o130-149i161-183o203-223i244-264o311-336i357-381o393-412i432-454o466-484i | CytoplasmicMembrane | 10 | |||||||
| YJEO_ECOLI | P39284 | yjeO | b4158 JW4119 | integral IM protein (SEC in IM), YjeO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.227 | TMH | 0 | 7.24951 | - | 3 | 2 | Y | n6-17c25/26o55-72i79-98o | CytoplasmicMembrane | 10 | 56 | ||||||
| MSCM_ECOLI | P39285 | mscM yjeP | yjeP | b4159 JW4120 | integral IM protein (SEC in IM), Miniconductance mechanosensitive channel MscM | Integral Inner Membrane | PMID: 22874652 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | Y | 20 | 0.667 | SpI | 19 | 8.61826 | - | 11 | 11 | Y | n3-14c19/20o476-496i517-539o551-576i597-617o629-649i670-691o697-718i785-808o828-848i879-897o903-930i | CytoplasmicMembrane | 10 | 15 | |||||
| ULAA_ECOLI | P39301 | ulaA sgaT yjfS | sgaT yjfS | b4193 JW5744 | integral IM protein (SEC in IM), Ascorbate-specific PTS system EIIC component UlaA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.105 | TMH | 0 | 3.53199 | - | 10 | 10 | N | o15-34i46-66o100-121i142-170o233-253i265-285o305-331i338-359o379-402i423-445o | CytoplasmicMembrane | 10 | ||||||
| YTFB_ECOLI | P39310 | ytfB | b4206 JW5745 | integral IM protein (SEC in IM), Cell division YtfB | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | no | yes | N | 57 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i30-48o | Extracellular | 9 | 57 | ||||||||
| YTFF_ECOLI | P39314 | ytfF | b4210 JW4168 | integral IM protein (SEC in IM), YtfF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.128 | TMH | 0 | 8.9392 | - | 10 | 10 | N | i5-25o31-52i64-86o92-113i125-142o154-175i195-216o231-255i262-281o287-306i | CytoplasmicMembrane | 10 | |||||||
| TAMB_ECOLI | P39321 | tamB ytfN ytfO | ytfN ytfO | b4221 JW4180 | integral IM protein (SEC in IM), Translocation and assembly module subunit TamB | Integral Inner Membrane | Part of the translocation and assembly module (TAM). TAM system promotes efficient secretion of autotransporters in proteobacteria. | PMID: 22466966 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 24 | 0.143 | SpI | 25 | 7.57895 | - | 1 | 0 | Y | n8-19c23/24o | Unknown | 4 | 31 | ||||
| YTFT_ECOLI | P39328 | ytfT | b4230 JW5753 | integral IM protein (SEC in IM), ABC transporter permease YtfT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 44 | 0.117 | TMH | 0 | 7.85185 | - | 10 | 10 | N | i21-39o59-77i84-103o109-130i137-155o175-195i224-246o258-275i282-304o310-329i | CytoplasmicMembrane | 10 | |||||||
| YJGN_ECOLI | P39338 | yjgN | b4257 JW5759 | integral IM protein (SEC in IM), YjgN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 57 | 0.116 | TMH | 0 | 3.32963 | - | 8 | 8 | N | o24-45i65-90o96-116i142-164o176-208i229-249o280-299i327-349o | CytoplasmicMembrane | 10 | |||||||
| IDNT_ECOLI | P39344 | idnT gntW yjgT | gntW yjgT | b4265 JW4222 | integral IM protein (SEC in IM), Gnt-II system L-idonate transporter IdnT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 46 | 0.134 | TMH | 0 | 10.8686 | - | 12 | 12 | N | i12-38o58-76i97-130o136-154i175-194o222-242i254-275o295-312i324-344o350-369i376-393o413-438i | CytoplasmicMembrane | 10 | ||||||
| YJGX_ECOLI | P39349 | yjgX | b4575 b4275/b4276/b4560 | integral IM protein (SEC in IM), Putative phosphoethanolamine transferase YjgX | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | N | 31 | 0.126 | TMH | 0 | 4.71526 | - | 1 | 1 | N | o6-25i | CytoplasmicMembrane | 10 | 49 | |||||||
| YJHB_ECOLI | P39352 | yjhB | b4279 JW5768 | integral IM protein (SEC in IM), Putative metabolite transport YjhB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 17 | 0.101 | TMH | 0 | 7.56655 | - | 11 | 12 | N | i21-41o53-73i85-105o111-129i141-160o166-185i215-235o247-271i283-302o308-327i339-362o368-392i | CytoplasmicMembrane | 10 | |||||||
| YJHE_ECOLI | P39355 | yjhE | b4282 | integral IM protein (SEC in IM), Putative YjhE | Integral Inner Membrane | B | - | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | no | no | N | 38 | 0.334 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i22-49o55-76i | CytoplasmicMembrane | 10 | 15 | ||||||||
| YJHF_ECOLI | P39357 | yjhF | b4296 JW4258 | integral IM protein (SEC in IM), permease YjhF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.161 | TMH | 0 | 4.20538 | - | 12 | 11 | Y | n3-13c17/18o27-44i56-76o99-129i136-154o174-193i228-249o261-285i305-327o347-380i387-405o425-448i | CytoplasmicMembrane | 10 | |||||||
| SGCC_ECOLI | P39365 | sgcC yjhN | yjhN | b4304 JW4266 | integral IM protein (SEC in IM), Putative permease IIC component SgcC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.12 | TMH | 0 | 10.5542 | - | 11 | 11 | N | o6-25i32-54o85-109i130-152o172-194i214-235o247-268i289-319o325-344i353-374o408-430i | CytoplasmicMembrane | 10 | ||||||
| YJIH_ECOLI | P39379 | yjiH | b4330 JW5783 | integral IM protein (SEC in IM), YjiH | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 38 | 0.143 | TMH | 0 | 5.26808 | - | 4 | 4 | N | i21-39o86-104i116-135o176-201i | CytoplasmicMembrane | 9 | 16 | ||||||||
| YJIJ_ECOLI | P39381 | yjiJ | b4332 JW4295 | integral IM protein (SEC in IM), YjiJ | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 43 | 0.129 | TMH | 0 | 16.3295 | - | 12 | 12 | N | i12-34o54-72i84-103o109-131i138-159o171-191i212-235o247-267i274-293o299-321i333-355o361-385i | CytoplasmicMembrane | 10 | |||||||||
| YJIK_ECOLI | P39382 | yjiK | b4333 JW5869 | integral IM protein (SEC in IM), YjiK | Belongs to the yjiK family. | Integral Inner Membrane | B | Bout | in/out | N/A | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 39 | 0.139 | SpI | 30 | 8.5892 | - | 1 | 1 | N | i12-28o | Unknown | 2 | 31 | |||||||
| YJIN_ECOLI | P39385 | yjiN | b4336 JW4299 | integral IM protein (SEC in IM), YjiN | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.127 | TMH | 0 | 11.0197 | - | 3 | 3 | N | i12-31o43-62i401-421o | CytoplasmicMembrane | 9 | |||||||||
| MDTM_ECOLI | P39386 | mdtM yjiO | yjiO | b4337 JW4300 | integral IM protein (SEC in IM), Multidrug resistance MdtM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.289 | TMH | 0 | 7.71747 | - | 12 | 11 | Y | n9-20c24/25o48-68i80-99o105-126i138-162o168-187i216-241o253-271i283-304o310-335i347-368o374-395i | CytoplasmicMembrane | 10 | ||||||
| BTST_ECOLI | P39396 | btsT yjiY | yjiY | b4354 JW5791 | integral IM protein (SEC in IM), Pyruvate/proton symporter BtsT | Integral Inner Membrane | PMID: 15919996 PMID: 22685278 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.119 | TMH | 0 | 7.29235 | - | 16 | 16 | N | i12-28o34-54i95-115o121-141i162-185o191-211i223-243o258-278i283-303o323-343i364-387o488-505i533-552o564-589i596-616o669-689i | CytoplasmicMembrane | 10 | ||||||
| LGOT_ECOLI | P39398 | lgoT yjiZ yjjL | yjiZ yjjL | b4356 JW4319 | integral IM protein (SEC in IM), Probable L-galactonate transporter LgoT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.161 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i39-56o108-127i170-192o198-217i260-279o299-321i333-352o358-385i397-415o421-442i | CytoplasmicMembrane | 10 | ||||||
| OPGB_ECOLI | P39401 | mdoB opgB yjjO | opgB yjjO | b4359 JW5794 | integral IM protein (SEC in IM), Phosphoglycerol transferase I MdoB | Integral Inner Membrane | Disulfide bond-containing protein PMID: 25664544 | PMID: 15919996 PMID: 25664544 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.198 | TMH | 0 | 5.71979 | - | 4 | 4 | Y | n4-14c18/19o28-47i59-74o80-98i110-128o | CytoplasmicMembrane | 10 | 7 | ||||
| TTDT_ECOLI | P39414 | ttdT ygjC ygjE | ygjC ygjE | b3063 JW3035 | integral IM protein (SEC in IM), L-tartrate/succinate antiporter TtdT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 30 | 0.161 | TMH | 0 | 15.2878 | - | 12 | 14 | N | i7-27o33-49i56-73o93-116i137-154o192-214i235-258o289-307i312-328o340-364i371-391o397-415i422-442o462-486i | CytoplasmicMembrane | 10 | ||||||
| TORS_ECOLI | P39453 | torS yccI | yccI | b0993 JW5135 | integral IM protein (SEC in IM), Sensor TorS | Integral Inner Membrane | Trimethylamine N-oxide (TMAO) respiration system is encoded by the torCAD operon and comprises a periplasmic TMAO reductase (TorA) and a c-type cytochrome (TorC), which shuttles electrons to TorA. Interaction studies showed that, when immature, TorC can no longer bind TorA efficiently but can bind the periplasmic detector region of sensor TorS. The immature C-terminal domain of TorC strongly down-regulated the tor operon and interacted with the TorS detector region. | PMID: 11562502 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.124 | TMH | 0 | 8.89656 | - | 2 | 2 | N | o12-31i331-352o | CytoplasmicMembrane | 10 | 13 | ||||
| YBAL_ECOLI | P39830 | ybaL ylaA | ylaA | b0478 JW0467 | integral IM protein (SEC in IM), Putative cation/proton antiporter YbaL | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.134 | TMH | 0 | 5.87955 | - | 12 | 12 | N | o6-26i33-51o57-76i88-112o118-136i148-168o180-206i227-260o280-299i306-328o334-361i368-387o | CytoplasmicMembrane | 10 | 36 | |||||
| ZNUB_ECOLI | P39832 | znuB yebI | yebI | b1859 JW1848 | integral IM protein (SEC in IM), High-affinity zinc uptake system ZnuB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.205 | TMH | 0 | 13.4596 | - | 7 | 9 | N | o6-28i33-51o57-74i86-107o127-145i166-183o189-207i214-233o239-256i | CytoplasmicMembrane | 10 | ||||||
| GNTT_ECOLI | P39835 | gntT gntM usgA yhgC | gntM usgA yhgC | b3415 JW5690 | integral IM protein (SEC in IM), High-affinity gluconate transporter GntT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.124 | TMH | 0 | 9.75395 | - | 11 | 9 | Y | n3-16c34/35o58-76i97-130o136-154i175-194o224-246i258-278o298-316i337-370o416-437i | CytoplasmicMembrane | 10 | 14 | |||||
| YFEH_ECOLI | P39836 | yfeH | b2410 JW5876 | integral IM protein (SEC in IM), Putative symporter YfeH | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.211 | TMH | 0 | 6.99994 | - | 8 | 10 | N | i7-24o30-48i69-89o101-119i126-152o164-181i202-221o227-250i262-283o289-311i | CytoplasmicMembrane | 10 | ||||||||||
| RCSD_ECOLI | P39838 | rcsD yojN yojP yojQ | yojN yojP yojQ | b2216 JW2204 | integral IM protein (SEC in IM), Phosphotransferase RcsD | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 45 | 0.148 | SpI | 40 | 6.36777 | - | 1 | 2 | N | o22-46i309-330o | CytoplasmicMembrane | 10 | 24 | |||||||
| QSEC_ECOLI | P40719 | qseC ygiY | ygiY | b3026 JW2994 | integral IM protein (SEC in IM), Sensor QseC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.271 | SpI | 34 | 9.27705 | - | 2 | 2 | N | i12-33o155-182i | CytoplasmicMembrane | 10 | 22 | |||||
| NANT_ECOLI | P41036 | nanT | b3224 JW3193 | integral IM protein (SEC in IM), Sialic acid transporter NanT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 58 | 0.109 | TMH | 0 | 3.96571 | - | 12 | 14 | N | i21-43o55-74i86-106o112-134i146-165o171-190i224-242o248-267i274-292o312-334i343-361o367-391i403-425o431-452i | CytoplasmicMembrane | 10 | |||||||
| GSPF_ECOLI | P41441 | gspF hofF hopF | hofF hopF | b3327 JW3289 | integral IM protein (SEC in IM), Putative type II secretion system F GspF | Integral Inner Membrane | Part of gsp locus. Homolog to type two secretion system proteins PulF. | PMID: 11118204 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 67 | 0.101 | CYT | 0 | -0.200913 | - | 3 | 4 | N | i164-186o217-236i248-268o370-391i | CytoplasmicMembrane | 10 | 16 | ||||
| GSPG_ECOLI | P41442 | gspG hofG hopG | hofG hopG | b3328 JW3290 | integral IM protein (SEC in IM), Putative type II secretion system G GspG | Integral Inner Membrane | Homolog to major pilin PulG (T2SS). Potential component of type II secretion system. GspG is the major pseudopillin GspG and may be involved in initiation, stabilization, regulation or capping of the periplasmic piston filaments to achieve secretion. Toget | PMID: 11118204 PMID: 14966662 PMID: 18241884 PMID: 20616068 PMID: 23006128 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 36 | 0.127 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i12-34o | CytoplasmicMembrane | 9 | 46 | |||||
| GSPH_ECOLI | P41443 | gspH hofH hopH | hofH hopH | b3329 JW3291 | integral IM protein (SEC in IM), Putative type II secretion system H GspH | Integral Inner Membrane | GspH is one of four low abundance pseudopillins together with GspI, J and K. These assemble together with the major pseudopillin GspG and may be involved in initiation, stabilization, regulation or capping of the periplasmic piston filaments to achieve se | PMID: 11118204 PMID: 17172336 PMID: 18241884 PMID: 18461043 PMID: 21890895 PMID: 23006128 | Integral Inner Membrane | B | - | N/A | Membrane anchored | SEC | T2S | no | yes | N | 29 | 0.113 | TMH | 0 | 4.86781 | - | 1 | 1 | N | o12-31i | CytoplasmicMembrane | 9 | 72 | ||||||
| YGJI_ECOLI | P42590 | ygjI | b3078 JW5512 | nucleoid & integral IM protein (SEC in IM), transporter YgjI | Integral Inner Membrane, Nucleoid | PMID: 15919996 PMID: 23138451 | Integral Inner Membrane, Nucleoid | B, N | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.124 | TMH | 0 | 5.79735 | - | 12 | 12 | N | i12-29o41-63i84-108o120-140i152-176o196-220i232-255o287-312i332-353o365-385i406-426o432-452i | CytoplasmicMembrane | 10 | ||||||||
| YGJQ_ECOLI | P42598 | ygjQ | b3086 JW3057 | integral IM protein (SEC in IM), YgjQ | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane | Periplasmic | SRP | SEC | no | yes | N | 37 | 0.199 | SpI | 36 | 6.02153 | - | 1 | 0 | Y | n21-31c36/37o | CytoplasmicMembrane | 9 | |||||||||
| ALX_ECOLI | P42601 | alx ygjT | ygjT | b3088 JW5515 | integral IM protein (SEC in IM), Putative membrane-bound redox modulator Alx | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.24 | TMH | 0 | 11.5369 | - | 9 | 9 | N | o6-29i41-63o83-102i114-136o142-161i205-229o235-255i267-286o292-311i | CytoplasmicMembrane | 10 | ||||||
| YGJV_ECOLI | P42603 | ygjV | b3090 JW3061 | integral IM protein (SEC in IM), YgjV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 56 | 0.156 | TMH | 0 | 4.26984 | - | 5 | 5 | N | o6-24i36-59o71-89i101-124o136-157i | CytoplasmicMembrane | 10 | |||||||
| MZRA_ECOLI | P42615 | mzrA ecfM yqjB | ecfM yqjB | b3096 JW3067 | integral IM protein (SEC in IM), Modulator of the activity of the EnvZ/OmpR two-component regulatory system MzrA | Integral Inner Membrane | PMID: 19432797 PMID: 20889743 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 30 | 0.154 | SpI | 29 | 4.521 | - | 1 | 0 | Y | n11-22c27/28o | Unknown | 2 | 14 | |||||
| YQJF_ECOLI | P42619 | yqjF | b3101 JW5850 | integral IM protein (SEC in IM), YqjF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 35 | 0.118 | TMH | 0 | 8.80873 | - | 4 | 4 | N | i7-26o46-66i73-91o103-122i | CytoplasmicMembrane | 10 | |||||||
| YHAM_ECOLI | P42626 | yhaM yhaN | yhaN | b4470 JW5518 | integral IM protein (SEC in IM), UPF0597 YhaM | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cytoplasmic | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | no | N | 43 | 0.167 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o319-340i | Cytoplasmic | 9 | 83 | |||||||
| DLST_ECOLI | P42628 | dlsT yhaO | yhaO | b3110 JW5519 | integral IM protein (SEC in IM), Probable serine transporter DlsT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 20 | 0.128 | TMH | 0 | 0.623427 | - | 11 | 11 | N | i38-58o64-82i111-135o155-173i185-206o221-243i264-285o318-339i360-381o387-411i423-442o | CytoplasmicMembrane | 10 | ||||||
| YHBX_ECOLI | P42640 | yhbX | b3173 JW5534 | integral IM protein (SEC in IM), Putative phosphoethanolamine transferase YhbX | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 32 | 0.175 | TMH | 0 | 13.1458 | - | 5 | 6 | N | i15-31o37-54i61-82o112-131i143-163o175-195i | CytoplasmicMembrane | 10 | |||||||
| PTPC2_ECOLI | P42905 | agaW | b3134 | integral IM protein (SEC in IM), Putative N-acetylgalactosamine permease IIC component 2 AgaW | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006), pseudogene (Uniprot) | no | yes | N | 70 | 0.132 | TMH | 0 | 6.59862 | - | 3 | 3 | N | o6-26i33-56o94-116i | CytoplasmicMembrane | 10 | 9 | |||||
| PTPC1_ECOLI | P42910 | agaC yraE | yraE | b3139 JW3108 | integral IM protein (SEC in IM), N-acetylgalactosamine permease IIC component 1 AgaC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 28 | 0.124 | TMH | 0 | 4.72274 | - | 6 | 4 | Y | n4-15c20/21o97-121i142-164o184-202i209-238o | CytoplasmicMembrane | 10 | 2 | |||||
| PTPD_ECOLI | P42911 | agaD yraF | yraF | b3140 JW3109 | integral IM protein (SEC in IM), N-acetylgalactosamine permease IID component AgaD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.125 | CYT | 0 | -0.200913 | - | 5 | 5 | N | i96-119o131-151i172-195o215-236i243-262o | CytoplasmicMembrane | 10 | 5 | |||||
| YNFM_ECOLI | P43531 | ynfM yzyC | yzyC | b1596 JW1588 | integral IM protein (SEC in IM), transport YnfM | Integral Inner Membrane | Phobius weak prediction of a hydrophobic TMIn the middle of sequence/Kyte-Doolittle predicts several hydrophobic patches. | PMID: 15919996 PMID: 19275539 PMID: 20608695 PMID: 3905795 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 53 | 0.119 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i37-59o71-91i103-122o128-149i156-175o187-208i240-261o267-285i306-323o329-352i364-386o392-411i | CytoplasmicMembrane | 10 | |||||
| YGAH_ECOLI | P43667 | ygaH | b2683 JW2658 | integral IM protein (SEC in IM), YgaH | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 18 | 0.142 | CYT | 0 | -0.200913 | - | 3 | 3 | Y | n5-15c20/21o36-57i69-85o91-109i | CytoplasmicMembrane | 10 | ||||||||||
| PQIB_ECOLI | P43671 | pqiB pqi5B | pqi5B | b0951 JW0934 | integral IM protein (SEC in IM), Intertransport PqiB | Integral Inner Membrane | PMID: 15919657 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 42 | 0.124 | TMH | 0 | 6.02674 | - | 1 | 1 | N | i20-38o | Unknown | 2 | ||||||
| PITB_ECOLI | P43676 | pitB | b2987 JW2955 | integral IM protein (SEC in IM), Probable low-affinity inorganic phosphate transporter 2 PitB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.141 | TMH | 0 | 10.6201 | - | 10 | 11 | N | o6-26i52-76o96-116i123-143o155-177i208-227o233-255i343-361o381-402i423-442o474-495i | CytoplasmicMembrane | 10 | 6 | ||||||
| YRBG_ECOLI | P45394 | yrbG | b3196 JW3163 | integral IM protein (SEC in IM), YrbG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 26 | 0.208 | CYT | 0 | -0.200913 | - | 9 | 9 | Y | n2-17c25/26o35-56i68-90o105-122i129-150o170-188i200-219o239-264i276-294o300-319i | CytoplasmicMembrane | 10 | |||||||
| DCUD_ECOLI | P45428 | dcuD yhcL | yhcL | b3227 JW3196 | integral IM protein (SEC in IM), Putative cryptic C4-dicarboxylate transporter DcuD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 30 | 0.172 | TMH | 0 | 2.68784 | - | 13 | 12 | N | i26-48o68-89i109-128o134-150i157-174o194-215i242-265o271-290i348-369o375-397i409-430o436-454i | CytoplasmicMembrane | 10 | ||||||
| YRAQ_ECOLI | P45468 | yraQ | b3151 JW3120 | integral IM protein (SEC in IM), UPF0718 YraQ | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 10 | 0.146 | TMH | 0 | 3.98221 | - | 9 | 9 | N | o15-32i72-95o115-134i146-167o173-191i227-249o261-280i287-305o325-345i | CytoplasmicMembrane | 10 | |||||||||
| KEFB_ECOLI | P45522 | kefB trkB | trkB | b3350 JW3313 | integral IM protein (SEC in IM), Glutathione-regulated potassium-efflux system KefB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.23 | TMH | 0 | 10.3228 | - | 13 | 13 | N | o6-25i32-50o56-75i87-107o113-135i147-171o183-201i213-231o237-255i267-285o291-312i324-343o355-373i | CytoplasmicMembrane | 10 | ||||||
| YHFK_ECOLI | P45537 | yhfK | b3358 JW5701 | integral IM protein (SEC in IM), YhfK | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 54 | 0.107 | TMH | 0 | 0.537733 | - | 9 | 11 | N | o38-55i67-85o91-108i115-133o139-160i371-388o394-411i418-435o441-457i464-481o487-509i | CytoplasmicMembrane | 10 | 6 | ||||||||
| FRLA_ECOLI | P45539 | frlA yhfM | yhfM | b3370 JW3333 | integral IM protein (SEC in IM), Probable fructoselysine/psicoselysine transporter FrlA | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 20 | 0.117 | TMH | 0 | 13.0134 | - | 11 | 12 | N | i12-32o44-66i87-113o125-143i155-175o195-219i231-256o276-302i327-347o353-375i387-406o412-434i | CytoplasmicMembrane | 10 | ||||||||
| YHFT_ECOLI | P45546 | yhfT | b3377 JW3340 | integral IM protein (SEC in IM), YhfT | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 22 | 0.311 | TMH | 0 | 0.362704 | - | 11 | 11 | N | o6-28i49-70o90-113i133-153o159-176i183-200o229-249i289-314o320-339i369-397o409-432i | CytoplasmicMembrane | 10 | |||||||||
| XAPB_ECOLI | P45562 | xapB | b2406 JW2397 | nucleoid & integral IM protein (SEC in IM), Xanthosine permease XapB | Integral Inner Membrane, Nucleoid | PMID: 15919996 | Integral Inner Membrane, Nucleoid | B, N | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 51 | 0.121 | TMH | 0 | 9.53241 | - | 12 | 12 | N | i12-30o42-62i71-88o94-114i135-154o160-178i212-235o255-275i282-301o307-327i348-369o381-402i | CytoplasmicMembrane | 10 | |||||||
| YHDT_ECOLI | P45566 | yhdT | b3257 JW3225 | integral IM protein (SEC in IM), YhdT | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.15 | TMH | 0 | 15.9222 | - | 2 | 2 | N | i12-33o45-65i | CytoplasmicMembrane | 9 | 43 | ||||||||
| YBCI_ECOLI | P45570 | ybcI | b0527 JW0516 | integral IM protein (SEC in IM), YbcI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.121 | TMH | 0 | 4.35035 | - | 4 | 4 | N | i27-47o59-78i85-103o149-170i | CytoplasmicMembrane | 10 | 4 | ||||||
| HOFO_ECOLI | P45751 | hofO yrfB | yrfB | b3393 JW3356 | integral IM protein (SEC in IM), DNA utilization HofO | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 40 | 0.213 | TMH | 0 | 6.9432 | - | 1 | 1 | N | o20-38i | Unknown | 2 | 19 | |||||||
| GSPA_ECOLI | P45756 | gspA yheD | yheD | b3323 JW3285 | integral IM protein (SEC in IM), Putative general secretion pathway A GspA | Integral Inner Membrane | C-terminus of GspA is in the periplasm. The protein fractionates with the inner membrane. Part of gsp locus. | PMID: 11118204 PMID: 21378198 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 37 | 0.16 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i237-257o | Cytoplasmic | 9 | 75 | ||||
| GSPC_ECOLI | P45757 | gspC yheE | yheE | b3324 JW3286 | integral IM protein (SEC in IM), Putative type II secretion system C GspC | Integral Inner Membrane | Homolog to type two secretion system proteins PulC. Potential component of type II secretion system. A representative PulC-PhoA hybrid protein fractionated mainly with the inner membrane upon isopycnic sucrose gradient centrifugation of membrane vesicles. PMID: 2677007 GspC is the inner membrane component of type II secretion system (T2SS). GspD and the inner membrane protein GspC interact with each other via periplasmic domains (observed in the crystal structure). PMID: 21931548 | PMID: 11118204 PMID: 14966662 PMID: 21931548 PMID: 2677007 | Integral Inner Membrane | B | Bin | out/in | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 18 | 0.127 | TMH | 0 | -0.020813 | - | 1 | 1 | N | o17-38i | Unknown | 2 | 27 | ||||
| GSPI_ECOLI | P45760 | gspI yheH | yheH | b3330 JW5706 | integral IM protein (SEC in IM), Putative type II secretion system I GspI | Integral Inner Membrane | Potential component of type II secretion system. GspI is one of four low abundance pseudopillins together with GspH, J and K. These assemble together with the major pseudopillin GspG and may be involved in initiation, stabilization, regulation or capping PMID: 11266368 | PMID: 11118204 PMID: 11266368 PMID: 14966662 PMID: 18241884 PMID: 21890895 PMID: 23006128 | Integral Inner Membrane | B | Bin | out/in | N/A | Periplasmic (Experimental) | SEC | T2S | no | yes | N | 24 | 0.233 | SpI | 23 | 3.86957 | - | 1 | 1 | N | o12-30i | CytoplasmicMembrane | 9 | 60 | |||||
| GSPL_ECOLI | P45763 | gspL yheK | yheK | b3333 JW5705 | integral IM protein (SEC in IM), Putative type II secretion system L GspL | Integral Inner Membrane | Potential component of type II secretion system. EspL (GspL homolog) protein interacts through its N-terminal cytoplasmic domain with EspL (GspL homolog) protein | PMID: 11118204 PMID: 14966662 PMCID: PMC398259 | Integral Inner Membrane | B | Binout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Cytoplasmic | SRP | SEC | no | yes | N | 45 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i242-260o | Unknown | 2 | 17 | ||||
| YHDX_ECOLI | P45767 | yhdX | b3269 JW5544 | integral IM protein (SEC in IM), Putative amino-acid ABC transporter permease YhdX | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 22 | 0.16 | TMH | 0 | 9.39948 | - | 8 | 8 | N | i21-40o92-114i126-146o181-200i220-241o261-280i335-353o359-384i | CytoplasmicMembrane | 10 | |||||||||
| YHDY_ECOLI | P45768 | yhdY | b3270 JW5545 | integral IM protein (SEC in IM), amino-acid ABC transporter permease YhdY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.123 | TMH | 0 | 1.0833 | - | 8 | 8 | N | i28-46o98-119i126-148o160-182i194-219o231-250i292-315o335-352i | CytoplasmicMembrane | 10 | |||||||
| IGAA_ECOLI | P45800 | yrfF | b3398 JW3361 | integral IM protein (SEC in IM), Putative IgaA homolog YrfF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.26 | SpI | 18 | 4.58634 | - | 5 | 5 | N | o6-22i206-223o229-247i337-358o652-674i | CytoplasmicMembrane | 10 | 26 | ||||||
| YHGE_ECOLI | P45804 | yhgE | b3402 JW3365 | integral IM protein (SEC in IM), YhgE | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.113 | TMH | 0 | 10.0663 | - | 11 | 11 | N | i12-33o39-59i66-84o99-118i138-163o183-201i213-236o248-268i289-308o320-341i353-373o | CytoplasmicMembrane | 10 | |||||||||
| YCIQ_ECOLI | P45848 | yciQ yciP | yciP | b1268 JW5197 | integral IM protein (SEC in IM), YciQ | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | no | yes | Y | 24 | 0.803 | SpI | 23 | 8.83165 | - | 5 | 5 | Y | n7-18c23/24o249-266i398-423o429-448i460-480o486-513i | CytoplasmicMembrane | 10 | |||||||||
| MTGA_ECOLI | P46022 | mtgA mgt yrbM | mgt yrbM | b3208 JW3175 | integral IM protein (SEC in IM), Biosynthetic PG transglycosylase MtgA | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 25 | 0.133 | TMH | 0 | 13.1588 | - | 1 | 1 | N | i21-41o | CytoplasmicMembrane | 10 | 11 | |||||||
| YBJC_ECOLI | P46119 | ybjC | b0850 JW0834 | integral IM protein (SEC in IM), YbjC | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.131 | TMH | 0 | 6.40394 | - | 2 | 2 | N | i12-29o44-68i | CytoplasmicMembrane | 9 | 45 | |||||||||
| YEDI_ECOLI | P46125 | yedI | b1958 JW1941 | integral IM protein (SEC in IM), YedI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.143 | CYT | 0 | -0.200913 | - | 5 | 5 | Y | n2-12c30/31o73-102i152-171o177-199i220-249o269-294i | CytoplasmicMembrane | 10 | 4 | ||||||
| ABGT_ECOLI | P46133 | abgT ydaH | ydaH | b1336 JW5822 ECK1332 | integral IM protein (SEC in IM), p-aminobenzoyl-glutamate transport AbgT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 55 | 0.352 | TMH | 0 | 3.72666 | - | 13 | 13 | N | i30-52o85-104i125-147o153-175i182-202o214-232i260-281o301-322i343-362o382-403i415-434o440-458i470-495o | CytoplasmicMembrane | 10 | ||||||
| YDDG_ECOLI | P46136 | yddG | b1473 JW1469 | integral IM protein (SEC in IM), Aromatic amino acid exporter YddG | Integral Inner Membrane | PMID: 15919996 PMID: 21042032 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.109 | TMH | 0 | 7.54403 | - | 10 | 9 | Y | n6-17c26/27o36-57i64-86o92-113i120-138o158-175i182-203o215-235i242-264o270-290i | CytoplasmicMembrane | 10 | |||||||
| DGCN_ECOLI | P46139 | dgcN yfiN | yfiN | b2604 JW2585 | integral IM protein (SEC in IM), Diguanylate cyclase DgcN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 67 | 0.12 | TMH | 0 | 11.5458 | - | 2 | 2 | N | i21-43o155-177i | CytoplasmicMembrane | 10 | ||||||
| YGBE_ECOLI | P46141 | ygbE | b2749 JW2719 | integral IM protein (SEC in IM), YgbE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.233 | TMH | 0 | 10.6872 | - | 3 | 3 | N | o23-46i53-79o85-106i | CytoplasmicMembrane | 10 | |||||||
| RSEC_ECOLI | P46187 | rseC | b2570 JW2554 | integral IM protein (SEC in IM), RseC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.187 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i79-98o104-121i | CytoplasmicMembrane | 10 | 27 | ||||||
| AAEX_ECOLI | P46478 | aaeX yhcR | yhcR | b3242 JW5541 | integral IM protein (SEC in IM), AaeX | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.106 | TMH | 0 | 10.7464 | - | 2 | 2 | N | o6-31i43-62o | CytoplasmicMembrane | 9 | 34 | |||||||
| AAEB_ECOLI | P46481 | aaeB yhcP | yhcP | b3240 JW3209 | integral IM protein (SEC in IM), p-hydroxybenzoic acid efflux pump subunit AaeB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 54 | 0.637 | TMH | 0 | 6.80417 | - | 10 | 10 | N | i13-32o38-56i68-87o93-112i119-135o371-395i407-426o432-449i461-480o486-503i | CytoplasmicMembrane | 10 | ||||||
| AAEA_ECOLI | P46482 | aaeA yhcQ | yhcQ | b3241 JW3210 | integral IM protein (SEC in IM), p-hydroxybenzoic acid efflux pump subunit AaeA | Integral Inner Membrane | PET family proteins are believed to be membrane localized, having 12 predicted transmembrane segments in gram-negative bacteria PMID: 10939244 PMID: 15489430 | PMID: 10939244 PMID: 15489430 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Periplasmic (Experimental) | SRP | SEC | yes | yes | N | 31 | 0.144 | SpI | 28 | 8.87913 | - | 1 | 1 | N | i12-32o | CytoplasmicMembrane | 9 | |||||
| YQGD_ECOLI | P46879 | yqgD | b2941 JW2908 | integral IM protein (SEC in IM), YqgD | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | pseudogene (Ecogene), pseudogene (Uniprot) | no | no | N | 62 | 0.118 | TMH | 0 | 1.01241 | - | 2 | 1 | N | o27-50i | CytoplasmicMembrane | 9 | |||||||||
| FTSK_ECOLI | P46889 | ftsK | b0890 JW0873 | nucleoid & integral IM protein (SEC in IM), DNA translocase FtsK | Integral Inner Membrane, Nucleoid | PMID: 11703663 PMID: 11948172 PMID: 15919996 PMID: 9723913 | Integral Inner Membrane, Nucleoid | B, N | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 53 | 0.169 | TMH | 0 | 6.50875 | - | 5 | 5 | N | i25-44o75-98i110-131o137-158i165-184o | CytoplasmicMembrane | 10 | 14 | ||||||
| AER_ECOLI | P50466 | aer air yqjJ | air yqjJ | b3072 JW3043 | integral IM protein (SEC-YidC in IM), Aerotaxis receptor Aer | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 PMID: 22380631 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC-YidC | yes | yes | N | 34 | 0.205 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i171-200o | CytoplasmicMembrane | 10 | 31 | ||||
| TORY_ECOLI | P52005 | torY yecK | yecK | b1873 JW1862 | integral IM protein (SEC in IM), Cytochrome c-type TorY | Integral Inner Membrane | Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorZ. Required for electron transfer to the TorZ terminal enzyme. PMID: 11004177 | PMID: 11004177 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 32 | 0.123 | SpI | 26 | 7.35562 | - | 1 | 0 | Y | n7-18c26/27o | Unknown | 4 | 44 | ||||
| FSR_ECOLI | P52067 | fsr | b0479 JW0468 | integral IM protein (SEC in IM), Fosmidomycin resistance protein Fsr | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 29 | 0.107 | TMH | 0 | 4.87385 | - | 10 | 11 | N | o26-50i62-84o104-130i151-175o181-202i223-242o262-282i294-313o319-340i352-375o381-399i | CytoplasmicMembrane | 10 | |||||||
| HISQ_ECOLI | P52094 | hisQ | b2308 JW2305 | integral IM protein (SEC in IM), Histidine transport system permease HisQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.408 | TMH | 0 | 6.17401 | - | 5 | 5 | N | o12-35i47-70o90-108i149-171o191-215i | CytoplasmicMembrane | 10 | 8 | ||||||
| GLRK_ECOLI | P52101 | glrK yfhK | yfhK | b2556 JW5407 | integral IM protein (SEC in IM), Sensor histidine kinase GlrK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.258 | SpI | 30 | 8.61403 | - | 2 | 1 | Y | n14-24c30/31o174-198i | CytoplasmicMembrane | 10 | 18 | |||||
| YPJK_ECOLI | P52134 | ypjK | b2635 JW5888 | integral IM protein (SEC in IM), YpjK | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 46 | 0.265 | TMH | 0 | 5.94794 | - | 3 | 1 | Y | n3-14c22/23o46-68i | CytoplasmicMembrane | 10 | |||||||||
| YFJW_ECOLI | P52138 | yfjW | b2642 JW2623 | integral IM protein (SEC in IM), YfjW | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 47 | 0.122 | TMH | 0 | 6.6613 | - | 5 | 6 | N | i20-46o66-89i96-118o130-151i163-188o536-557i | CytoplasmicMembrane | 10 | ||||||||
| EMRY_ECOLI | P52600 | emrY | b2367 JW2364 | integral IM protein (SEC-YidC in IM), Probable multidrug resistance EmrY | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 40 | 0.184 | TMH | 0 | 10.5527 | - | 13 | 13 | N | i12-32o55-73i85-104o110-132i144-165o171-193i205-224o236-255i276-295o307-325i337-355o375-394i484-502o | CytoplasmicMembrane | 10 | ||||||
| YCCM_ECOLI | P52636 | yccM | b0992 JW0977 | integral IM protein (SEC in IM), Putative electron transport YccM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 48 | 0.107 | CYT | 0 | -0.200913 | - | 5 | 5 | N | i37-54o96-114i159-180o200-218i307-332o | CytoplasmicMembrane | 10 | 12 | ||||||
| YDBH_ECOLI | P52645 | ydbH | b1381 JW1376 | integral IM protein (SEC in IM), YdbH | Uncharacterized, echolocation Signal peptide may be membrane anchored or cleaved and the protein therefore exported (signalP score near threshold). BOMP reliability scores are below 2 and so this is unlikely to be an OMP. | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | no | yes | N | 35 | 0.163 | TMH | 0 | 6.49797 | - | 1 | 0 | Y | n7-26c34/35o | CytoplasmicMembrane | 9 | 12 | ||||||||
| YBHD_ECOLI | P52696 | ybhD | b0768 JW5896 | nucleoid & integral IM protein (SEC in IM), HTH-type transcriptional regulator YbhD | Integral Inner Membrane, Nucleoid | Uncharacterized HTH-type transcriptional regulator | Integral Inner Membrane, Nucleoid | B, N | N/A | Membrane anchored | SRP | SEC | no | yes | N | 24 | 0.184 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i94-112o | Cytoplasmic | 9 | ||||||||||
| MNGA_ECOLI | P54745 | mngA hrsA | hrsA | b0731 JW0720 | integral IM protein (SEC in IM), PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC component MngA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.104 | CYT | 0 | -0.200913 | - | 9 | 8 | N | i310-337o357-376i388-414o434-454i466-486o498-518i574-596o616-641i | CytoplasmicMembrane | 10 | 37 | |||||
| YGCG_ECOLI | P55140 | ygcG | b2778 JW5445 | integral IM protein (SEC in IM), UPF0603 YgcG | Integral Inner Membrane | B | Bpoly | - | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | Y | 18 | 0.242 | SpI | 17 | 4.90841 | - | 2 | 3 | Y | n4-12c17/18o176-194i206-222o228-249i | CytoplasmicMembrane | 10 | |||||||||
| YGAP_ECOLI | P55734 | ygaP | b2668 JW2643 | integral IM protein (SEC in IM), YgaP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 12 | 0.121 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i117-135o141-165i | CytoplasmicMembrane | 10 | 28 | ||||||
| YJJZ_ECOLI | P55914 | yjjZ | b4567 JW5797 | integral IM protein (SEC in IM), YjjZ | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.223 | TMH | 0 | 9.90172 | - | 3 | 3 | N | i7-25o31-48i55-75o | CytoplasmicMembrane | 9 | 19 | |||||||||
| CYDX_ECOLI | P56100 | cydX ybgT | ybgT | b4515 JW0724 | integral IM protein (SEC-YidC in IM), Cytochrome bd-I ubiquinol oxidase subunit X CydX | Integral Inner Membrane | Found to co-fractionate with the inner membrane. Experimentally verified orientation: N(out)-C(in). Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreased. | PMID: 19121005 PMID: 21778229 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | Cytoplasmic | SRP | SEC-YidC | no | yes | N | 24 | 0.168 | SpI | 23 | 3.08714 | - | 1 | 0 | Y | n4-15c23/24o | Unknown | 2 | |||||
| PTHC_ECOLI | P56579 | srlA gutA sbl | gutA sbl | b2702 JW5429 | integral IM protein (SEC in IM), PTS system glucitol/sorbitol-specific EIIC component SrlA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 46 | 0.112 | CYT | 0 | -0.200913 | - | 3 | 3 | N | o22-48i69-91o122-149i | CytoplasmicMembrane | 10 | 17 | |||||
| PTHB_ECOLI | P56580 | srlE gutA gutE | gutA gutE | b2703 JW5430 | integral IM protein (SEC in IM), PTS system glucitol/sorbitol-specific EIIB component SrlE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 22 | 0.109 | CYT | 0 | -0.200913 | - | 4 | 6 | N | i147-165o177-197i204-226o232-250i257-280o300-318i | CytoplasmicMembrane | 10 | 17 | |||||
| BLR_ECOLI | P56976 | blr | b4409 JW5963 | integral IM protein (SEC in IM), Divisome-associated Blr | Integral Inner Membrane | Small membrane protein detected experimentally. | PMID: 10931331 PMID: 19121005 PMID: 22885295 | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.106 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-26o | CytoplasmicMembrane | 10 | ||||||
| YMGF_ECOLI | P58034 | ymgF | b4520 JW1156 | integral IM protein (SEC in IM), YmgF | Integral Inner Membrane | PMID: 18978050 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.129 | TMH | 0 | 0.559611 | - | 2 | 2 | N | i12-31o37-59i | CytoplasmicMembrane | 9 | 24 | ||||||
| ADIC_ECOLI | P60061 | adiC aniC yjdD yjdE | aniC yjdD yjdE | b4115 JW4076 | integral IM protein (SEC in IM), Arginine/agmatine antiporter AdiC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 62 | 0.127 | TMH | 0 | 8.65108 | - | 12 | 12 | N | i12-35o41-61i91-116o122-141i153-173o193-217i229-254o274-296i317-340o352-374i386-404o410-428i | CytoplasmicMembrane | 10 | ||||||
| YOHJ_ECOLI | P60632 | yohJ | b2141 JW2129 | integral IM protein (SEC in IM), UPF0299 YohJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 30 | 0.138 | TMH | 0 | 13.9988 | - | 4 | 4 | N | i12-32o38-55i67-86o92-113i | CytoplasmicMembrane | 10 | 15 | ||||||
| MSBA_ECOLI | P60752 | msbA | b0914 JW0897 | integral IM protein (SEC in IM), Lipid A export ATP-binding/permease MsbA | Integral Inner Membrane | PMID: 15919996 PMID: 8809774 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 39 | 0.127 | TMH | 0 | 7.05231 | - | 5 | 6 | N | i21-45o65-93i142-163o169-186i244-269o275-295i | CytoplasmicMembrane | 10 | 11 | ||||||
| TSGA_ECOLI | P60778 | tsgA gutS yhfC yhfH | gutS yhfC yhfH | b3364 JW3327 | integral IM protein (SEC in IM), TsgA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.126 | TMH | 0 | 17.4563 | - | 12 | 12 | N | i12-35o47-66i78-97o103-122i134-157o163-183i204-229o249-268i273-289o295-317i329-352o358-381i | CytoplasmicMembrane | 10 | ||||||
| PLSY_ECOLI | P60782 | plsY ygiH | ygiH | b3059 JW3031 | integral IM protein (SEC in IM), Probable glycerol-3-phosphate acyltransferase PlsY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.12 | TMH | 0 | 1.31378 | - | 5 | 5 | N | o6-28i49-68o80-102i109-132o138-158i | CytoplasmicMembrane | 10 | 17 | |||||
| AQPZ_ECOLI | P60844 | aqpZ bniP | bniP | b0875 JW0859 | integral IM protein (SEC-YidC in IM), Aquaporin Z AqpZ | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidCPMID: 22108384. AqpZ forms tetramer in the inner membranePMID: 14691544. Sucrose gradient sedimentation analysis showed that the native, solubilized AqpZ protein is a trypsin-resistant tetramerPMID: 10518952. Upon reconstitution into proteoliposomes, AqpZ displays very high osmotic water permeability. No permeation by glycerol, urea or sorbitol was detectedPMID: 10518952. Electron crystallography has shown monomers to consist of six membrane spanning alpha-helices confirming sequence based predictionsPMID: 10487750. | PMID: 10487750 PMID: 10518952 PMID: 11266632 PMID: 14691544 PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 43 | 0.268 | TMH | 0 | 14.8231 | - | 6 | 5 | Y | n5-17c26/27o36-60i81-103o129-149i161-180o206-226i | CytoplasmicMembrane | 10 | |||||
| YBJL_ECOLI | P60869 | ybjL | b0847 JW0831 | integral IM protein (SEC in IM), Putative transport YbjL | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 23 | 0.115 | TMH | 0 | 4.04335 | - | 9 | 10 | N | o12-30i37-55o61-85i92-114o161-181i383-403o409-426i447-464o476-498i532-557o | CytoplasmicMembrane | 10 | |||||||||
| YIDE_ECOLI | P60872 | yidE yibE | yibE | b3685 JW3662 | integral IM protein (SEC in IM), Putative transport YidE | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.131 | TMH | 0 | 7.15912 | - | 10 | 11 | N | o6-22i29-47o67-86i93-115o162-182i371-391o397-417i429-446o466-485i492-513o533-552i | CytoplasmicMembrane | 10 | ||||||||
| UPPP_ECOLI | P60932 | uppP bacA upk | bacA upk | b3057 JW3029 | integral IM protein (SEC in IM), Undecaprenyl-diphosphatase UppP | Integral Inner Membrane | PMID: 15138271 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.112 | TMH | 0 | 2.62176 | - | 7 | 7 | Y | n6-13c18/19o50-69i90-110o116-136i157-175o195-213i225-246o252-272i | CytoplasmicMembrane | 10 | ||||||
| LGT_ECOLI | P60955 | lgt umpA | umpA | b2828 JW2796 | integral IM protein (SEC in IM), Prodiacylglyceryl transferase Lgt | Integral Inner Membrane | PMID: 15919996 PMID: 8051048 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.128 | TMH | 0 | 9.00412 | - | 5 | 7 | N | o14-40i60-80o100-118i130-148o200-218i225-242o262-282i | CytoplasmicMembrane | 10 | 10 | |||||
| OPGH_ECOLI | P62517 | mdoH opgH | opgH | b1049 JW1037 | integral IM protein (SEC in IM), Glucans biosynthesis glucosyltransferase H MdoH | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. OpgH localizes to the nascent septal site, where it antagonizes assembly of the tubulin-like cell division protein FtsZ, delaying division and increasing cell size. | PMID: 15919657 PMID: 15919996 PMID: 9008159 PMCID: PMC3723540 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP (exp) | SEC | yes | yes | N | 35 | 0.119 | CYT | 0 | -0.200913 | - | 6 | 8 | N | i139-156o188-221i512-533o566-590i599-617o623-640i660-676o682-706i | CytoplasmicMembrane | 10 | 3 | ||||
| YEIH_ECOLI | P62723 | yeiH | b2158 JW2145 | integral IM protein (SEC in IM), UPF0324 YeiH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 41 | 0.241 | TMH | 0 | 13.02 | - | 8 | 11 | N | i12-32o38-58i79-98o104-122i134-151o163-185i197-219o225-246i266-284o290-311i323-344o | CytoplasmicMembrane | 10 | |||||||
| KUP_ECOLI | P63183 | kup trkD | trkD | b3747 JW5609 | integral IM protein (SEC in IM), Low affinity potassium transport system kup | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | yes | N | 23 | 0.142 | TMH | 0 | 5.56396 | - | 12 | 11 | Y | n9-17c22/23o48-69i102-129o141-157i169-190o210-233i245-267o287-316i337-357o363-383i395-413o419-440i | CytoplasmicMembrane | 10 | |||||
| GADC_ECOLI | P63235 | gadC acsA xasA | acsA xasA | b1492 JW1487 | integral IM protein (SEC in IM), Probable glutamate/gamma-aminobutyrate antiporter GadC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.285 | TMH | 0 | 15.6618 | - | 12 | 12 | N | i12-30o42-66i87-108o128-146i158-178o198-217i238-260o288-310i337-356o368-392i413-432o444-466i | CytoplasmicMembrane | 10 | ||||||
| YQEG_ECOLI | P63340 | yqeG | b2845 JW2813 | integral IM protein (SEC in IM), transport YqeG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 23 | 0.142 | TMH | 0 | 9.79347 | - | 10 | 11 | N | i12-30o36-53i92-112o124-145i152-173o193-216i236-261o281-302i334-355o361-381i390-408o | CytoplasmicMembrane | 10 | |||||||
| ZNTB_ECOLI | P64423 | zntB ydaN | ydaN | b1342 JW1336 | integral IM protein (SEC in IM), Zinc transport ZntB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.108 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i268-289o301-321i | CytoplasmicMembrane | 10 | 82 | |||||
| YPFJ_ECOLI | P64429 | ypfJ | b2475 JW2460 | integral IM protein (SEC in IM), YpfJ | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Membrane | Membrane anchored | SRP | SEC | yes | yes | N | 33 | 0.101 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i38-58o | Unknown | 2 | |||||||||
| YPJD_ECOLI | P64432 | ypjD | b2611 JW2592 | integral IM protein (SEC in IM), YpjD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 18 | 0.156 | CYT | 0 | -0.200913 | - | 8 | 7 | Y | n3-12c17/18o33-51i63-84o90-112i124-146o176-198i210-226o238-258i | CytoplasmicMembrane | 10 | |||||||
| YBJM_ECOLI | P64439 | ybjM | b0848 JW0832 | integral IM protein (SEC in IM), YbjM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.187 | TMH | 0 | 12.0012 | - | 4 | 4 | N | i7-28o40-57i64-83o95-117i | CytoplasmicMembrane | 10 | 52 | ||||||
| YCEO_ECOLI | P64442 | yceO | b1058 JW1045 | integral IM protein (SEC in IM), YceO | Integral Inner Membrane | Small membrane protein detected experimentally. | PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 16 | 0.097 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i25-45o | CytoplasmicMembrane | 9 | |||||||
| YNAJ_ECOLI | P64445 | ynaJ | b1332 JW1326 | integral IM protein (SEC in IM), YnaJ | Integral Inner Membrane | B | Bout | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.241 | TMH | 0 | 15.6597 | - | 2 | 1 | Y | n15-26c31/32o55-80i | CytoplasmicMembrane | 9 | 29 | ||||||||
| ORTT_ECOLI | P64453 | ortT ydcX | ydcX | b1445 JW5232 | integral IM protein (SEC in IM), Orphan toxin OrtT | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 19 | 0.119 | TMH | 0 | 10.662 | - | 2 | 2 | N | o6-25i37-56o | CytoplasmicMembrane | 9 | ||||||||
| YDHI_ECOLI | P64471 | ydhI | b1643 JW1635 | integral IM protein (SEC in IM), YdhI | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.128 | TMH | 0 | 10.2168 | - | 2 | 2 | N | o20-44i56-77o | CytoplasmicMembrane | 9 | 43 | ||||||||
| YDJM_ECOLI | P64481 | ydjM | b1728 JW5281 | integral IM protein (SEC in IM), YdjM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 28 | 0.333 | CYT | 0 | -0.200913 | - | 0 | 4 | Y | n7-17c22/23o32-48i69-90o110-128i149-166o | CytoplasmicMembrane | 10 | 15 | ||||||
| YEAQ_ECOLI | P64485 | yeaQ | b1795 JW1784 | integral IM protein (SEC in IM), UPF0410 YeaQ | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 18 | 0.108 | TMH | 0 | 15.2932 | - | 3 | 3 | N | o6-21i28-52o58-77i | CytoplasmicMembrane | 10 | |||||||||
| YEBO_ECOLI | P64499 | yebO | b1825 JW1814 | integral IM protein (SEC in IM), YebO | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell membrane | Membrane anchored | SRP | SEC | yes | yes | N | 36 | 0.143 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o12-32i | Unknown | 2 | 46 | ||||||||
| MGRB_ECOLI | P64512 | mgrB yobG | yobG | b1826 JW1815 | integral IM protein (SEC in IM), PhoP/PhoQ regulator MgrB | Integral Inner Membrane | Small membrane protein detected experimentally. Localization and bacterial two-hybrid studies suggest that MgrB resides in the inner-membrane and interacts directly with PhoQ. | PMID: 19121005 PMID: 20041203 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | Periplasmic | SEC | no | yes | N | 22 | 0.24 | SpI | 21 | 10.2239 | - | 1 | 0 | Y | n6-17c21/22o | CytoplasmicMembrane | 9 | 53 | |||||
| YECN_ECOLI | P64515 | yecN | b1869 JW5308 | integral IM protein (SEC in IM), YecN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Single-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 21 | 0.119 | CYT | 0 | -0.200913 | - | 3 | 2 | Y | n4-14c18/19o72-92i104-122o | CytoplasmicMembrane | 10 | 50 | ||||||
| YEIS_ECOLI | P64536 | yeiS | b2145 JW5359 | integral IM protein (SEC in IM), YeiS | Integral Inner Membrane | B | - | IM (predicted) | Membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.124 | TMH | 0 | 2.78571 | - | 2 | 2 | N | o6-24i54-77o | CytoplasmicMembrane | 9 | 57 | |||||||||
| YFGG_ECOLI | P64545 | yfgG | b2504 JW5399 | integral IM protein (SEC in IM), YfgG | Integral Inner Membrane | B | Binout | in/out | N/A | Membrane | Membrane anchored | SRP | SEC | no | yes | N | 41 | 0.141 | TMH | 0 | 3.8997 | - | 1 | 0 | Y | n20-31c39/40o | CytoplasmicMembrane | 9 | |||||||||
| AlaE_ECOLI | P64550 | alaE ygaW | ygaW | b2670 JW2645 | integral IM protein (SEC in IM), L-alanine exporter AlaE | Integral Inner Membrane | PMID: 21531828 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 49 | 0.117 | TMH | 0 | 6.24909 | - | 4 | 4 | N | i12-36o42-62i82-104o110-131i | CytoplasmicMembrane | 10 | 12 | |||||
| YGGT_ECOLI | P64564 | yggT | b2952 JW2919 | integral IM protein (SEC in IM), YggT | Potential substrate of periplasmic chaperone YfgM. PMID: 25403562 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | YfgM | yes | yes | N | 31 | 0.194 | TMH | 0 | 0.565687 | - | 4 | 4 | N | o6-25i67-91o97-119i144-165o | CytoplasmicMembrane | 10 | 5 | ||||||
| YQJD_ECOLI | P64581 | yqjD | b3098 JW3069 | integral IM protein (SEC in IM), YqjD | Integral Inner Membrane | YqJD is expressed during the stationary growth phase. YqjD possesses a transmembrane motif in the C-terminal region and associates with 70S and 100S ribosomes at the N-terminal region. Expressed during the stationary growth phase, and expression is regulated by stress response sigma factor RpoS. YqjD possesses a transmembrane motif in the C-terminal region and associates with 70S and 100S ribosomes at the N-terminal region. PMID: 22661687 YqjD is an inner membrane protein associated with stationary-phase ribosomes. PMID: 22661687 | PMID: 22380631 PMID: 22661687 | Integral Inner Membrane | B | Bout | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 33 | 0.103 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o81-99i | Unknown | 2 | |||||||
| YQJE_ECOLI | P64585 | yqjE | b3099 JW3070 | integral IM protein (SEC in IM), YqjE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 62 | 0.126 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i50-76o82-104i | CytoplasmicMembrane | 10 | |||||||
| YHAH_ECOLI | P64590 | yhaH | b3103 JW3074 | integral IM protein (SEC in IM), YhaH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.122 | TMH | 0 | 8.08221 | - | 3 | 3 | N | o23-40i52-70o82-103i | CytoplasmicMembrane | 10 | 8 | ||||||
| YHAI_ECOLI | P64592 | yhaI | b3104 JW3075 | integral IM protein (SEC in IM), YhaI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.264 | TMH | 0 | 0.961473 | - | 3 | 3 | N | i23-44o50-68i80-98o | CytoplasmicMembrane | 10 | 28 | ||||||
| MLAE_ECOLI | P64606 | mlaE yrbE | yrbE | b3194 JW3161 | integral IM protein (SEC in IM), Interphospholipid transport system permease MlaE | Integral Inner Membrane | PMID: 15919996 PMID: 19383799 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 67 | 0.105 | CYT | 0 | -0.200913 | - | 5 | 6 | N | i48-69o75-96i103-125o148-177i198-219o239-258i | CytoplasmicMembrane | 10 | ||||||
| YHDU_ECOLI | P64619 | yhdU | b3263 JW3231 | integral IM protein (SEC in IM), YhdU | Potential Signal Peptide | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 31 | 0.117 | TMH | 0 | 0.197917 | - | 1 | 0 | Y | n7-18c30/31o | CytoplasmicMembrane | 9 | 82 | |||||||
| YHFU_ECOLI | P64631 | yhfU | b3378 JW5697 | integral IM protein (SEC in IM), YhfU | Integral Inner Membrane | B | Binout | out/in | N/A | Membrane anchored | SRP | SEC | no | yes | N | 37 | 0.114 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o47-69i | Unknown | 2 | 90 | |||||||||
| HOFN_ECOLI | P64634 | hofN yrfC | yrfC | b3394 JW3357 | integral IM protein (SEC in IM), DNA utilization HofN | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 49 | 0.175 | TMH | 0 | 3.72613 | - | 1 | 1 | N | i21-40o | CytoplasmicMembrane | 9 | 22 | |||||||
| GHOT_ECOLI | P64646 | ghoT yjdO | yjdO | b4559 JW5732 | integral IM protein (SEC in IM), Toxin GhoT | Integral Inner Membrane | Toxin-antitoxin system Ghot-GhoS.In vitro RNA degradation studies, quantitative real-time reverse-transcription PCR and whole-transcriptome studies revealed that GhoS masks GhoT toxicity by cleaving specifically yjdO (ghoT) mRNA. | PMID: 22941047 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 33 | 0.1 | TMH | 0 | 9.94204 | - | 2 | 2 | N | i7-26o32-56i | CytoplasmicMembrane | 9 | |||||
| YGDQ_ECOLI | P67127 | ygdQ | b2832 JW2800 | integral IM protein (SEC in IM), UPF0053 YgdQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 49 | 0.35 | TMH | 0 | 3.66789 | - | 7 | 7 | N | o12-38i50-71o77-101i122-141o153-172i184-201o213-230i | CytoplasmicMembrane | 10 | 17 | ||||||
| YHGN_ECOLI | P67143 | yhgN | b3434 JW3397 | integral IM protein (SEC in IM), UPF0056 YhgN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 26 | 0.114 | CYT | 0 | -0.200913 | - | 6 | 6 | N | o6-27i39-57o63-85i106-127o139-162i174-195o | CytoplasmicMembrane | 10 | 37 | ||||||
| YQFA_ECOLI | P67153 | yqfA | b2899 JW2867 | integral IM protein (SEC in IM), UPF0073 YqfA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 49 | 0.173 | TMH | 0 | 3.45027 | - | 7 | 7 | N | i21-42o54-74i86-105o111-132i139-157o163-186i195-216o | CytoplasmicMembrane | 10 | |||||||
| YQHA_ECOLI | P67244 | yqhA | b3002 JW2971 | integral IM protein (SEC in IM), UPF0114 YqhA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 32 | 0.15 | TMH | 0 | 6.53453 | - | 3 | 4 | N | o12-32i53-75o109-126i138-156o | CytoplasmicMembrane | 10 | 15 | ||||||
| XANQ_ECOLI | P67444 | xanQ ygfO | ygfO | b2882 JW2850 | integral IM protein (SEC in IM), Xanthine permease XanQ | Integral Inner Membrane | PMID: 15919996 PMID: 16096267 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 59 | 0.123 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i24-50o56-74i81-104o116-142i154-175o187-204i211-231o251-275i338-360o366-388i395-412o424-446i | CytoplasmicMembrane | 10 | ||||||
| YOBD_ECOLI | P67601 | yobD | b1820 JW1809 | integral IM protein (SEC in IM), UPF0266 YobD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.285 | TMH | 0 | 3.32601 | - | 2 | 3 | N | o6-24i45-62o68-87i | CytoplasmicMembrane | 10 | |||||||
| AAER_ECOLI | P67662 | aaeR yhcS | yhcS | b3243 JW3212 | nucleoid & integral IM protein (SEC in IM), HTH-type transcriptional activator AaeR | Integral Inner Membrane, Nucleoid | PMID: 23138451 | Integral Inner Membrane, Nucleoid | B, N | IM (predicted) | Cytoplasmic | SRP | SEC | yes | yes | N | 24 | 0.199 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i226-245o | Cytoplasmic | 9 | |||||||||
| YFEO_ECOLI | P67729 | yfeO | b2389 JW2386 | integral IM protein (SEC in IM), Putative ion-transport YfeO | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.188 | TMH | 0 | 12.9661 | - | 11 | 11 | N | i12-37o57-77i98-117o147-170i182-203o223-245i257-281o301-318i325-340o346-364i371-398o | CytoplasmicMembrane | 10 | |||||||||
| MALG_ECOLI | P68183 | malG | b4032 JW3992 | integral IM protein (SEC in IM), Maltose/maltodextrin transport system permease MalG | Integral Inner Membrane | Signal recognition particle is required for insertion in the bacterial inner membrane. SRP pathway inhibition blocks membrane insertion. Crystal structure of a catalytic intermediate of the maltose transporter. PMID: 18033289 | PMID: 15919996 PMID: 18033289 PMID: 18456666 PMID: 2233678 PMID: 9008159 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP (exp) | SEC | no | yes | N | 37 | 0.136 | TMH | 0 | 14.3943 | - | 6 | 6 | N | i12-39o91-110i122-143o163-181i202-227o258-281i | CytoplasmicMembrane | 10 | ||||||
| ATPL_ECOLI | P68699 | atpE papH uncE | papH uncE | b3737 JW3715 | integral IM protein (YidC in IM), ATP synthase subunit c AtpE | Integral Inner Membrane | Experimentally verified gene-productPMID: 9868784. Methionine start codon is cleavedPMID: 9868784. Fractionation analysis indicates that upon YidC depletion the protein membrane localization is significantly decreasedPMID: 15263011PMID: 21778229. PMID: 9237612 | PMID: 15263011 PMID: 15919996 PMID: 21778229 PMID: 9237612 PMID: 9868784 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | YidC | no | yes | N | 28 | 0.117 | TMH | 0 | 7.95599 | - | 2 | 2 | N | o12-32i53-76o | CytoplasmicMembrane | 10 | 56 | ||||
| DHSC_ECOLI | P69054 | sdhC cybA | cybA | b0721 JW0711 | integral IM protein (SEC in IM), Succinate dehydrogenase cytochrome b556 subunit SdhC | Integral Inner Membrane | Alpha-helcal transmembrane protein (experimental). Transmembrane helices: 3 PMID: 12560550. | PMID: 11266632 PMID: 12560550 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.129 | TMH | 0 | 1.73943 | - | 3 | 3 | N | i20-48o68-89i110-128o | CytoplasmicMembrane | 10 | 42 | ||||
| MDTI_ECOLI | P69210 | mdtI ydgE | ydgE | b1599 JW1591 | integral IM protein (SEC in IM), Spermidine export MdtI | Integral Inner Membrane | PMID: 15919996 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 56 | 0.185 | TMH | 0 | 3.45748 | - | 4 | 4 | N | o6-25i37-56o62-84i91-108o | CytoplasmicMembrane | 10 | 14 | |||||
| MDTJ_ECOLI | P69212 | mdtJ ydgF | ydgF | b1600 JW1592 | integral IM protein (SEC in IM), Spermidine export MdtJ | Integral Inner Membrane | PMID: 15919996 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.125 | TMH | 0 | 7.68505 | - | 4 | 3 | Y | n3-13c21/22o31-52i59-80o86-102i | CytoplasmicMembrane | 10 | 36 | |||||
| MDTH_ECOLI | P69367 | mdtH yceL | yceL | b1065 JW1052 | integral IM protein (SEC in IM), Multidrug resistance MdtH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 8 | 0.11 | TMH | 0 | 12.8944 | - | 10 | 12 | N | i12-35o41-58i78-94o100-116i136-157o163-185i210-235o247-264i276-294o300-317i337-357o369-388i | CytoplasmicMembrane | 10 | ||||||
| FIEF_ECOLI | P69380 | fieF yiiP | yiiP | b3915 JW3886 | integral IM protein (SEC in IM), Ferrous-iron efflux pump FieF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.141 | TMH | 0 | 3.82255 | - | 6 | 6 | N | i12-33o39-60i81-106o118-138i158-175o181-199i | CytoplasmicMembrane | 10 | ||||||
| TATC_ECOLI | P69423 | tatC mttB yigU yigV | mttB yigU yigV | b3839 JW3815 | integral IM protein (SEC-YidC in IM), Sec-independent translocase TatC | Integral Inner Membrane | PMID: 11591389 PMID: 15225613 PMID: 15919996 PMID: 20169075 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 39 | 0.339 | TMH | 0 | 4.27208 | - | 6 | 6 | N | i20-38o74-95i116-137o157-183i195-212o218-237i | CytoplasmicMembrane | 10 | 65 | |||||
| TATB_ECOLI | P69425 | tatB mttA2 ysgB | mttA2 ysgB | b3838 JW5580 | integral IM protein (SEC in IM), Sec-independent translocase TatB | Integral Inner Membrane | PMID: 11591389 PMID: 14580344 PMID: 15225613 PMID: 20169075 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 44 | 0.115 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n9-20c28/29o | CytoplasmicMembrane | 10 | ||||||
| TATA_ECOLI | P69428 | tatA mttA1 yigT | mttA1 yigT | b3836 JW3813 | integral IM protein (SEC in IM), Sec-independent translocase TatA | Integral Inner Membrane | TatA-GFP was distributed in the membrane, often with higher abundance at the poles. PMID: 14580344 | PMID: 11591389 PMID: 14580344 PMID: 15225613 PMID: 20169075 | Integral Inner Membrane | B | Bin | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.112 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-22i | CytoplasmicMembrane | 10 | |||||
| PGAD_ECOLI | P69432 | pgaD ycdP | ycdP | b1021 JW1006 | integral IM protein (SEC in IM), Biofilm PGA synthesis PgaD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 38 | 0.135 | TMH | 0 | 10.5144 | - | 2 | 2 | N | i16-36o56-74i | CytoplasmicMembrane | 10 | 9 | |||||
| CCME_ECOLI | P69490 | ccmE yejS | yejS | b2197 JW2185 | integral IM protein (SEC in IM), Cytochrome c-type biogenesis CcmE | Integral Inner Membrane | CcmC, CcmE, and heme interact directly with each other, establishing a periplasmic heme delivery pathway for cytochrome c maturation. PMID: 11384983 PMID: 9770295 PMID: 16364305 | PMID: 11384983 PMID: 16364305 PMID: 9770295 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 29 | 0.181 | TMH | 0 | 8.60358 | - | 1 | 1 | N | i9-30o | Cytoplasmic | 8 | 66 | ||||
| AMTB_ECOLI | P69681 | amtB ybaG | ybaG | b0451 JW0441 | integral IM protein (SEC-YidC in IM), Ammonia channel AmtB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. PMID: 9720863 PMID: 10231487 PMID: 11847102 PMID: 14668330 | PMID: 10231487 PMID: 11266632 PMID: 11847102 PMID: 14668330 PMID: 15361618 PMID: 15919996 PMID: 22108384 PMID: 9720863 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | yes | yes | Y | 23 | 0.645 | SpI | 22 | 12.8449 | - | 12 | 11 | Y | n3-14c22/23o32-54i66-86o120-142i149-171o183-205i217-236o248-268i280-297o303-324i336-356o376-396i | CytoplasmicMembrane | 10 | |||||
| MBHS_ECOLI | P69739 | hyaA | b0972 JW0954 | integral IM protein (TAT in IM), Hydrogenase-1 small chain HyaA | Integral Inner Membrane | Exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven. PMID: 2180913 PMID: 1856178 PMID: 9738917 | PMID: 15919996 PMID: 17218314 PMID: 1856178 PMID: 2180913 PMID: 9738917 | Integral Inner Membrane | B | Bout | out/in | N/A | Cell inner membrane; Single-pass type I membrane protein; Periplasmic side | Integral Membrane Protein (Experimental) | TAT | yes | yes | N | 46 | 0.373 | SpI | 45 | 1.06961 | - | 2 | 1 | Y | n25-36c45/46o327-348i | CytoplasmicMembrane | 10 | 38 | ||||||
| PTGCB_ECOLI | P69786 | ptsG glcA umg | glcA umg | b1101 JW1087 | integral IM protein (SEC in IM), PTS system glucose-specific EIICB component PtsG | Integral Inner Membrane | PMID: 12717030 PMID: 15650111 PMID: 15919657 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.133 | TMH | 0 | 12.5578 | - | 10 | 9 | N | o16-39i51-71o77-101i113-132o152-172i254-272o278-297i304-331o354-376i | CytoplasmicMembrane | 10 | 3 | |||||
| PTXB_ECOLI | P69789 | glvB glvC | glvC | b3682 JW3659 | integral IM protein (SEC in IM), Phosphotransferase enzyme IIB component GlvB | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | no | N | 45 | 0.17 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o12-31i | CytoplasmicMembrane | 9 | 33 | ||||||
| PTNC_ECOLI | P69801 | manY pel ptsP | pel ptsP | b1818 JW1807 | integral IM protein (SEC in IM), PTS system mannose-specific EIIC component ManY | Integral Inner Membrane | PTS transport system component and membrane localized in complexomics study by (Stenberg et al., 2005) | PMID: 15911532 PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 26 | 0.11 | TMH | 0 | 6.083 | - | 7 | 7 | N | o6-24i33-56o62-86i98-124o144-165i177-197o209-239i | CytoplasmicMembrane | 10 | |||||
| PTND_ECOLI | P69805 | manZ gptB ptsM | gptB ptsM | b1819 JW1808 | integral IM protein (SEC in IM), PTS system mannose-specific EIID component ManZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.108 | CYT | 0 | -0.200913 | - | 3 | 3 | N | i130-154o238-255i262-282o | CytoplasmicMembrane | 10 | 29 | |||||
| PTMCB_ECOLI | P69826 | cmtA | b2933 JW2900 | integral IM protein (SEC-YidC in IM), PTS system mannitol-specific cryptic EIICB component CmtA | Integral Inner Membrane | Mannitol-specific cryptic phosphotransferase enzyme IIA component. Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 12558186 PMID: 15919996 PMID: 22108384 PMID: 9260961 PMID: 9525892 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 51 | 0.119 | TMH | 0 | 14.5212 | - | 8 | 8 | N | i12-40o52-74i86-114o134-158i214-235o247-266i287-307o313-335i | CytoplasmicMembrane | 10 | ||||||
| PTKC_ECOLI | P69831 | gatC | b2092 JW2076 | integral IM protein (SEC in IM), PTS system galactitol-specific EIIC component GatC | Integral Inner Membrane | PTS system galactitol-specific EIIC component.The galactitol phosphotransferase system transporter (EIIGat) is also composed of three subunits, GatA (IIAGat), GatB (IIBGat), and GatC (IICGat). These three subunits assemble in a 1:1:2 stoichiometry to form a complex with a predicted molecular mass of ???122 kDa | PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | no | yes | N | 34 | 0.145 | TMH | 0 | 0.817461 | - | 11 | 11 | N | o12-29i41-58o91-113i134-158o178-198i218-239o245-264i298-322o328-346i353-371o417-435i | CytoplasmicMembrane | 10 | |||||
| SUGE_ECOLI | P69937 | sugE | b4148 JW5738 | integral IM protein (SEC in IM), Quaternary ammonium compound-resistance SugE | Integral Inner Membrane | Dual topology membrane protein: can insert into the membrane in both directions. PMID: 15919996 | PMID: 14728684 PMID: 15919996 PMID: 16429150 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | in/out, out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 61 | 0.195 | TMH | 0 | 10.6118 | - | 4 | 3 | Y | n4-12c17/18o33-50i57-79o85-103i | CytoplasmicMembrane | 10 | ||||||
| WCAD_ECOLI | P71238 | wcaD | b2056 JW2041 | integral IM protein (SEC in IM), Putative colanic acid polymerase WcaD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 26 | 0.141 | TMH | 0 | 2.50534 | - | 11 | 11 | N | i7-25o31-48i55-73o85-105i117-138o172-191i203-226o246-266i278-296o328-347i368-397o | CytoplasmicMembrane | 10 | |||||||
| WCAJ_ECOLI | P71241 | wcaJ | b2047 JW2032 | integral IM protein (SEC in IM), UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase WcaJ | Integral Inner Membrane | PMID: 15919996 PMID: 22408159 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.107 | TMH | 0 | 4.26813 | - | 5 | 5 | N | i12-34o46-69i81-101o113-137i279-300o | CytoplasmicMembrane | 10 | |||||||
| AFUB_ECOLI | P75681 | afuB fbpB | fbpB | b0263 JW0255 | integral IM protein (SEC in IM), Putative ferric transport system permease-like AfuB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | N | 46 | 0.154 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i33-56o76-101i | CytoplasmicMembrane | 9 | 30 | ||||
| YAGG_ECOLI | P75683 | yagG | b0270 JW0263 | integral IM protein (SEC in IM), Putative glycoside/cation symporter YagG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | yes | no | N | 58 | 0.129 | TMH | 0 | 4.66722 | - | 12 | 12 | N | i12-34o40-59i80-101o107-130i150-172o178-199i233-255o267-287i294-311o317-340i360-384o404-426i | CytoplasmicMembrane | 10 | ||||||
| RCLC_ECOLI | P75685 | rclC ykgB | ykgB | b0301 JW5038 | integral IM protein (SEC in IM), RclC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.117 | TMH | 0 | 0.0510112 | - | 3 | 4 | N | i12-32o87-105i112-133o153-175i | CytoplasmicMembrane | 10 | ||||||
| YAHN_ECOLI | P75693 | yahN | b0328 JW0320 | integral IM protein (SEC in IM), YahN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 20 | 0.167 | TMH | 0 | 6.85455 | - | 6 | 6 | N | o20-42i54-79o85-103i136-153o159-179i199-217o | CytoplasmicMembrane | 10 | 45 | ||||||
| YBBV_ECOLI | P75711 | ybbV | b0510 JW0498 | integral IM protein (SEC in IM), YbbV | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 61 | 0.11 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o15-33i | Unknown | 2 | ||||||||||
| ALLP_ECOLI | P75712 | ybbW glxB2 | glxB2 | b0511 JW0499 | integral IM protein (SEC in IM), Putative allantoin permease YbbW | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 43 | 0.107 | TMH | 0 | 1.55234 | - | 12 | 12 | N | i46-79o91-110i117-139o151-174i186-212o224-245i266-288o308-328i349-367o373-397i417-439o451-468i | CytoplasmicMembrane | 10 | ||||||
| RZPD_ECOLI | P75719 | rzpD ybcT | ybcT | b0556 JW5079 | integral IM protein (SEC in IM), Prophage Rz endopeptidase RzpD | Integral Inner Membrane | Required for normal curli ex<x>pression and biofilm development. | PMID: 23378572 | Integral Inner Membrane | B | - | N/A | Periplasmic | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 23 | 0.233 | SpI | 22 | 3.631 | - | 1 | 0 | Y | n6-17c22/23o | Unknown | 2 | 28 | |||||
| DTPD_ECOLI | P75742 | dtpD ybgH | ybgH | b0709 JW0699 | integral IM protein (SEC in IM), Dipeptide permease D DtpD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.16 | TMH | 0 | 1.28832 | - | 14 | 14 | N | i12-36o48-69i78-96o102-121i142-162o168-187i208-231o237-255i267-284o304-332i344-365o377-398i410-430o462-479i | CytoplasmicMembrane | 10 | ||||||
| ABRB_ECOLI | P75747 | abrB ybgN | ybgN | b0715 JW5097 ECK0704 | integral IM protein (SEC in IM), Putative regulator AbrB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 23 | 0.182 | TMH | 0 | 11.997 | - | 7 | 9 | N | o6-32i53-75o81-103i144-162o174-200i207-224o230-247i259-280o323-343i | CytoplasmicMembrane | 10 | ||||||
| ZITB_ECOLI | P75757 | zitB ybgR | ybgR | b0752 JW0735 | integral IM protein (SEC in IM), Zinc transporter ZitB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 52 | 0.121 | TMH | 0 | 5.6947 | - | 5 | 6 | N | i21-41o47-68i89-110o122-143i155-182o188-205i | CytoplasmicMembrane | 10 | ||||||
| YBHI_ECOLI | P75763 | ybhI | b0770 JW0753 | integral IM protein (SEC in IM), YbhI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 27 | 0.378 | TMH | 0 | 13.1359 | - | 15 | 14 | N | i7-25o31-48i55-71o91-108i120-141o147-166i178-198o218-244i273-291o297-315i327-345o365-381i388-415o445-468i | CytoplasmicMembrane | 10 | |||||||
| YBHM_ECOLI | P75769 | ybhM | b0787 JW0770 | integral IM protein (SEC in IM), YbhM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 41 | 0.18 | TMH | 0 | 4.77792 | - | 7 | 7 | N | i21-41o53-70i77-98o104-129i136-155o161-179i209-229o | CytoplasmicMembrane | 10 | 67 | ||||||
| YBHN_ECOLI | P75770 | ybhN | b0788 JW0771 | integral IM protein (SEC in IM), YbhN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.118 | TMH | 0 | 10.4723 | - | 8 | 7 | Y | n14-27c31/32o47-65i85-106o126-151i163-186o206-227i234-266o286-303i | CytoplasmicMembrane | 10 | |||||||
| YBHG_ECOLI | P75777 | ybhG | b0795 JW0779 | integral IM protein (SEC in IM), UPF0194 YbhG | Integral Inner Membrane | PMID: 17446557 | Integral Inner Membrane | B | 0 | Soluble IM Fraction | Periplasm | Membrane anchored | SRP | SEC | yes | yes | N | 26 | 0.132 | SpI | 20 | 6.65671 | - | 1 | 0 | Y | n6-16c20/21o | CytoplasmicMembrane | 9 | 31 | |||||||
| YBIO_ECOLI | P75783 | ybiO | b0808 JW5108 | integral IM protein (SEC in IM), Moderate conductance mechanosensitive channel YbiO | Integral Inner Membrane | PMID: 15919996 PMID: 22874652 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | Y | 19 | 0.624 | SpI | 18 | 12.9319 | - | 11 | 11 | Y | n3-13c18/19o141-163i183-205o225-244i268-286o292-315i335-361o381-399i419-446o466-488i509-531o537-559i | CytoplasmicMembrane | 10 | 22 | ||||||
| OPGE_ECOLI | P75785 | opgE ybiP | ybiP | b0815 JW0800 | integral IM protein (SEC in IM), Phosphoethanolamine transferase OpgE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 22 | 0.112 | TMH | 0 | 6.83717 | - | 4 | 4 | N | o34-54i63-84o104-127i139-158o | CytoplasmicMembrane | 10 | 6 | |||||
| YBIR_ECOLI | P75788 | ybiR | b0818 JW0802 | integral IM protein (SEC in IM), YbiR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 39 | 0.126 | TMH | 0 | 6.01785 | - | 9 | 10 | N | o14-32i44-64o84-108i120-140o160-182i202-217o223-241i248-268o312-335i347-369o | CytoplasmicMembrane | 10 | |||||||
| GSIC_ECOLI | P75798 | gsiC yliC | yliC | b0831 JW0815 | integral IM protein (SEC in IM), Glutathione transport system permease GsiC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.137 | TMH | 0 | 6.79337 | - | 6 | 6 | N | i9-30o99-123i135-155o170-191i227-249o278-299i | CytoplasmicMembrane | 10 | 2 | |||||
| GSID_ECOLI | P75799 | gsiD yliD | yliD | b0832 JW0816 | integral IM protein (SEC in IM), Glutathione transport system permease GsiD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 66 | 0.123 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i40-61o103-129i136-158o164-183i222-247o267-290i | CytoplasmicMembrane | 10 | 10 | |||||
| PDEI_ECOLI | P75800 | pdeI yliE | yliE | b0833 JW0817 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 28 | 0.121 | TMH | 0 | 1.46888 | - | 2 | 2 | N | i12-32o286-304i | CytoplasmicMembrane | 7 | 4 | |||||
| DGCI_ECOLI | P75801 | dgcI yliF | yliF | b0834 JW0818 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.568 | SpI | 23 | 7.00044 | - | 2 | 1 | Y | n7-17c25/26o231-251i | CytoplasmicMembrane | 10 | 10 | |||||
| YBJG_ECOLI | P75806 | ybjG | b0841 JW5112 | integral IM protein (SEC in IM), Putative undecaprenyl-diphosphatase YbjG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.216 | TMH | 0 | 2.64993 | - | 4 | 5 | N | o20-48i60-80o100-119i126-144o150-168i | CytoplasmicMembrane | 10 | 9 | ||||||
| YBJJ_ECOLI | P75810 | ybjJ | b0845 JW0829 | integral IM protein (SEC in IM), YbjJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.184 | TMH | 0 | 16.9774 | - | 12 | 12 | N | i15-32o52-71i78-98o104-124i145-164o170-187i217-234o254-275i282-301o307-328i340-358o370-389i | CytoplasmicMembrane | 10 | |||||||
| YBJT_ECOLI | P75822 | ybjT | b0869 JW5116 | integral IM protein (SEC in IM), Putative NAD(P)-binding YbjT | Integral Inner Membrane | B | Bout | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 20 | 0.113 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o446-464i | CytoplasmicMembrane | 9 | 18 | ||||||||
| LYSO_ECOLI | P75826 | lysO ybjE | ybjE | b0874 JW0858 | integral IM protein (SEC in IM), Lysine exporter LysO | No TMH predictions | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 25 | 0.234 | TMH | 0 | 5.36895 | - | 8 | 9 | N | o6-23i35-55o61-83i104-129o135-155i167-188o208-228i249-267o279-297i | CytoplasmicMembrane | 10 | |||||||
| MACA_ECOLI | P75830 | macA ybjY | ybjY | b0878 JW0862 | integral IM protein (SEC in IM), Macrolide export MacA | Integral Inner Membrane | The crystal structure of MacA has been determined at 3.0A resolution. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein MacA to form a functional tripartite complex. Electron microscopic indicates that the MacA hexamer interacts with TolCIn a tip-to-tip manner. PMID: 11544226 PMID: 17214741 | PMID: 11544226 PMID: 17214741 PMID: 19254725 PMID: 21325274 PMID: 21890895 | Integral Inner Membrane | B | N/A | Cell inner membrane | Membrane anchored | SEC | yes | yes | N | 32 | 0.134 | SpI | 31 | 3.90027 | - | 1 | 1 | N | i12-29o | CytoplasmicMembrane | 7 | 45 | |||||||
| MACB_ECOLI | P75831 | macB ybjZ | ybjZ | b0879 JW0863 | integral IM protein (SEC in IM), Macrolide export ATP-binding/permease MacB | Integral Inner Membrane | The crystal structure of MacA has been determined at 3.0A resolution. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein MacA to form a functional tripartite complex. Electron microscopic indicates that the MacA hexamer interacts with TolCIn a tip-to-tip manner. | PMID: 11544226 PMID: 17214741 PMID: 19254725 PMID: 21325274 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.136 | CYT | 0 | -0.200913 | - | 4 | 4 | N | i273-293o523-548i572-602o608-631i | CytoplasmicMembrane | 10 | 17 | ||||
| YCAM_ECOLI | P75835 | ycaM | b0899 JW5119 | integral IM protein (SEC in IM), transporter YcaM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 35 | 0.133 | TMH | 0 | 12.317 | - | 12 | 12 | N | i12-30o42-63i84-102o126-146i153-176o196-218i239-261o293-312i344-364o384-402i414-435o447-470i | CytoplasmicMembrane | 10 | |||||||
| YCAP_ECOLI | P75839 | ycaP | b0906 JW0889 | integral IM protein (SEC in IM), UPF0702 transYcaP | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 64 | 0.104 | TMH | 0 | 0.694512 | - | 3 | 3 | N | o18-37i49-69o75-96i | Cytoplasmic | 8 | 26 | ||||||||
| SSUC_ECOLI | P75851 | ssuC ycbM | ycbM | b0934 JW5121 | integral IM protein (SEC in IM), Putative aliphatic sulfonates transport permease SsuC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.119 | TMH | 12 | 0 | 0 | 7 | 7 | N | i12-34o69-92i104-122o128-147i168-185o191-211i223-245o | CytoplasmicMembrane | 10 | 6 | |||||
| YCCS_ECOLI | P75870 | yccS | b0960 JW5128 | integral IM protein (SEC in IM), YccS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.115 | TMH | 0 | 6.42867 | - | 9 | 12 | N | i15-34o40-57i64-81o87-105i112-133o139-161i389-410o416-433i440-459o465-482i487-503o509-531i | CytoplasmicMembrane | 10 | |||||||
| GFCA_ECOLI | P75885 | gfcA ymcD | ymcD | b0987 JW5133 | integral IM protein (SEC in IM), Threonine-rich GfcA | Integral Inner Membrane | When the protein is over-expressed protein is located on the Inner Membrane. | PMID: 15919996 | Integral Inner Membrane | B | out/out | IM (predicted) | Cell inner membrane; Single-pass membrane protein | Membrane anchored | SRP | SEC | no | yes | Y | 22 | 0.858 | SpI | 21 | 31.9353 | - | 2 | 0 | Y | n5-16c21/22o | CytoplasmicMembrane | 10 | 113 | |||||
| RUTG_ECOLI | P75892 | rutG ycdG | ycdG | b1006 JW5137 | integral IM protein (SEC in IM), Putative pyrimidine permease RutG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 43 | 0.115 | CYT | 0 | -0.200913 | - | 11 | 12 | N | i33-54o60-76i83-103o109-129i141-161o173-190i197-219o239-261i281-299o319-338i350-373o385-418i | CytoplasmicMembrane | 10 | ||||||
| EFEU_ECOLI | P75901 | efeU ycdN | ycdN | b4490 JW5141/JW1002 b1016/b1017 | integral IM protein (SEC in IM), Putative inactive ferrous iron permease EfeU | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | N | 16 | 0.112 | CYT | 0 | -0.200913 | - | 6 | 7 | N | o6-26i38-58o70-90i117-142o148-171i183-203o248-265i | CytoplasmicMembrane | 10 | |||||||
| PGAC_ECOLI | P75905 | pgaC ycdQ | ycdQ | b1022 JW1007 | integral IM protein (SEC in IM), Poly-beta-1,6-N-acetyl-D-glucosamine synthase PgaC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 23 | 0.19 | TMH | 0 | 17.09 | - | 5 | 4 | Y | n6-17c22/23o32-54i323-345o365-383i395-417o | CytoplasmicMembrane | 10 | 17 | |||||
| DGCT_ECOLI | P75908 | dgcT ycdT | ycdT | b1025 JW5143 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.126 | TMH | 0 | 10.4982 | - | 8 | 8 | N | i12-29o41-67i79-99o114-131i151-169o189-213i220-241o261-278i | CytoplasmicMembrane | 10 | ||||||
| YCDU_ECOLI | P75910 | ycdU | b1029 JW1015 | integral IM protein (SEC in IM), YcdU | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 36 | 0.12 | TMH | 0 | 7.11263 | - | 8 | 8 | N | i16-32o44-68i89-114o120-141i162-182o202-222i255-277o289-309i | CytoplasmicMembrane | 10 | |||||||||
| YCDZ_ECOLI | P75916 | ycdZ | b1036 JW5147 | integral IM protein (SEC in IM), YcdZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 65 | 0.232 | TMH | 0 | 14.4904 | - | 5 | 5 | N | o20-42i49-70o76-94i99-117o123-147i | CytoplasmicMembrane | 10 | |||||||
| OPGC_ECOLI | P75920 | mdoC opgC ymdD | opgC ymdD | b1047 JW1034 | integral IM protein (SEC in IM), Glucans biosynthesis C MdoC | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.12 | TMH | 0 | 12.3178 | - | 10 | 10 | N | i17-38o58-80i92-113o133-157i177-201o213-234i246-264o276-295i307-330o336-356i | CytoplasmicMembrane | 10 | ||||||||
| C56I_ECOLI | P75925 | yceJ | b1057 JW1044 | integral IM protein (SEC in IM), Cytochrome b561 homolog 2 YceJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 31 | 0.121 | TMH | 0 | 13.644 | - | 4 | 4 | N | i12-35o55-72i92-111o144-164i | CytoplasmicMembrane | 10 | 10 | ||||||
| YCFT_ECOLI | P75955 | ycfT | b1115 JW1101 | integral IM protein (SEC in IM), YcfT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 33 | 0.109 | TMH | 0 | 11.9971 | - | 8 | 8 | N | i12-32o52-70i90-113o133-156i163-183o195-212i224-256o310-331i | CytoplasmicMembrane | 10 | |||||||
| LOLE_ECOLI | P75958 | lolE ycfW | ycfW | b1118 JW1104 | integral IM protein (SEC in IM), Lipoprotein-releasing system TM protein LolE | Integral Inner Membrane | PMID: 10783239 PMID: 15276320 PMID: 17498646 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 36 | 0.113 | TMH | 0 | 6.76692 | - | 4 | 4 | N | i21-48o270-293i314-341o380-399i | CytoplasmicMembrane | 10 | 20 | |||||
| YCFZ_ECOLI | P75961 | ycfZ | b1121 JW1107 | integral IM protein (SEC in IM), YcfZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 19 | 0.268 | SpI | 20 | 7.80323 | - | 4 | 3 | Y | n4-14c19/20o183-201i208-230o242-259i | CytoplasmicMembrane | 10 | |||||||
| YMFA_ECOLI | P75962 | ymfA | b1122 JW5164 | integral IM protein (SEC in IM), YmfA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 29 | 0.212 | TMH | 0 | 6.47267 | - | 2 | 2 | N | i7-28o117-139i | CytoplasmicMembrane | 10 | |||||||
| YMFE_ECOLI | P75968 | ymfE | b1138 JW5166 | integral IM protein (SEC in IM), YmfE | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 37 | 0.102 | TMH | 0 | 1.7441 | - | 4 | 4 | N | i21-39o59-79i151-173o185-208i | CytoplasmicMembrane | 10 | 7 | |||||||
| Y1142_ECOLI | P75971 | b1142 | b1142 JW1128 | integral IM protein (SEC in IM), Putative b1142 B114 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot), pseudogene (Ecogene), pseudogene (Ochman & Davalos, 2006) | no | no | N | 63 | 0.119 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i41-62o74-92i | Unknown | 2 | 54 | |||||||
| YMFR_ECOLI | P75979 | ymfR | b1150 JW1136 | integral IM protein (SEC in IM), YmfR | Integral Inner Membrane | B | Binout | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 22 | 0.153 | TMH | 0 | 11.0494 | - | 2 | 1 | Y | n4-17c21/22o31-49i | CytoplasmicMembrane | 9 | 16 | |||||||
| PDEG_ECOLI | P75995 | pdeG ycgG | ycgG | b1168 JW5174 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SEC | no | yes | N | 33 | 0.194 | CYT | 0 | -0.200913 | - | 2 | 2 | N | o6-28i221-239o | CytoplasmicMembrane | 7 | |||||||
| NHAP2_ECOLI | P76007 | cvrA nhaP2 ycgO | nhaP2 ycgO | b1191 JW5184 | integral IM protein (SEC in IM), K(+)/H(+) antiporter NhaP2 CvrA | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.165 | TMH | 0 | 9.70846 | - | 11 | 13 | N | o6-23i30-47o59-76i88-113o119-141i162-179o191-210i217-237o243-261i273-292o298-323i335-357o363-381i | CytoplasmicMembrane | 10 | ||||||||
| YMGE_ECOLI | P76011 | ymgE tag | tag | b1195 JW1184 | integral IM protein (SEC in IM), UPF0410 YmgE | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.106 | TMH | 0 | 11.3901 | - | 3 | 3 | N | o6-21i28-47o59-81i | CytoplasmicMembrane | 10 | 16 | |||||||
| PUUP_ECOLI | P76037 | puuP ycjJ | ycjJ | b1296 JW1289 | integral IM protein (SEC in IM), Putrescine importer PuuP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 43 | 0.116 | TMH | 0 | 2.35137 | - | 12 | 12 | N | i24-47o59-77i98-120o132-150i162-182o202-221i241-264o291-319i340-359o365-386i398-417o423-442i | CytoplasmicMembrane | 10 | ||||||
| YNBA_ECOLI | P76090 | ynbA | b1408 JW1405 | integral IM protein (SEC in IM), YnbA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 50 | 0.126 | TMH | 0 | -0.193337 | - | 5 | 5 | N | o31-64i85-107o113-132i152-168o174-191i | CytoplasmicMembrane | 10 | 11 | ||||||
| YNBB_ECOLI | P76091 | ynbB | b1409 JW1406 | integral IM protein (SEC in IM), YnbB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 60 | 0.122 | TMH | 0 | 8.47225 | - | 9 | 7 | Y | n6-16c21/22o37-54i61-83o95-119i131-154o166-187i208-227o233-253i | CytoplasmicMembrane | 10 | |||||||
| YNBD_ECOLI | P76093 | ynbD | b1411 JW1408 | integral IM protein (SEC in IM), YnbD | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.123 | TMH | 0 | 13.3648 | - | 8 | 8 | Y | n4-15c33/34o49-72i84-105o125-141i153-170o176-193i213-236o242-261i273-292o | CytoplasmicMembrane | 10 | |||||||||
| YDCO_ECOLI | P76103 | ydcO | b1433 JW5229 | integral IM protein (SEC in IM), YdcO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 27 | 0.198 | TMH | 0 | 15.9189 | - | 10 | 12 | Y | n10-20c25/26o41-63i70-88o94-114i119-138o144-161i168-187o207-224i236-254o260-276i288-313o319-337i349-382o | CytoplasmicMembrane | 10 | |||||||
| YDCZ_ECOLI | P76111 | ydcZ | b1447 JW1442 | integral IM protein (SEC in IM), YdcZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 61 | 0.165 | TMH | 0 | 8.79151 | - | 5 | 4 | Y | n4-19c24/25o34-55i67-88o94-114i126-145o | CytoplasmicMembrane | 10 | 14 | ||||||
| SAFA_ECOLI | P76136 | safA yneN | yneN | b1500 JW1494.1 | integral IM protein (SEC in IM), Two-component-system connector SafA | Integral Inner Membrane | PMID: 17998538 | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell inner membrane | - | SRP | SEC | no | yes | N | 40 | 0.109 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o19-40i | CytoplasmicMembrane | 9 | ||||||
| YNEE_ECOLI | P76146 | yneE | b1520 JW5245 | integral IM protein (SEC in IM), UPF0187 YneE | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 38 | 0.113 | TMH | 0 | 13.5444 | - | 3 | 4 | N | i28-46o52-70i208-229o235-255i | CytoplasmicMembrane | 9 | |||||||||
| DGCF_ECOLI | P76147 | dgcF yneF | yneF | b1522 JW5825 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | no | no | N | 34 | 0.118 | TMH | 0 | 9.08181 | - | 4 | 4 | N | o12-29i41-68o80-102i114-135o | CytoplasmicMembrane | 10 | 31 | ||||
| YNFA_ECOLI | P76169 | ynfA | b1582 JW1574 | integral IM protein (SEC in IM), UPF0060 YnfA | Integral Inner Membrane | Dual topology membrane protein: can insert into the membrane in both directions. PMID: 15919996 | PMID: 11867724 PMID: 15919996 PMID: 16429150 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | out/out, in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 62 | 0.224 | TMH | 0 | 10.6101 | - | 4 | 4 | N | o6-26i33-54o60-78i85-105o | CytoplasmicMembrane | 10 | ||||||
| YNFH_ECOLI | P76173 | ynfH | b1590 JW5261 | integral IM protein (SEC in IM), Anaerobic dimethyl sulfoxide reductase chain YnfH | Integral Inner Membrane | The physiological substrate and relevance of the YnfFGH S- and N-oxide reductase is unknown. DmsC paralog. So far, hydroxy pyridine N-oxide is the best substrate for YnfFGH. ynfFGH are expressed anaerobically. YnfH can function with DmsAB, replacing DMSC a The ynfEFGHI operon is a paralogue of the Escherichia coli dmsABC operon. ynfE and ynfF are paralogues of dmsA. ynfG and ynfH are paralogues of dmsB and dmsC, respectively. PMID: 14522592 | PMID: 14522592 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.15 | TMH | 0 | 13.2137 | - | 8 | 8 | N | o12-34i46-67o87-104i116-138o150-169i181-204o224-243i250-271o | CytoplasmicMembrane | 10 | ||||||
| CLCB_ECOLI | P76175 | clcB mriT ynfJ | mriT ynfJ | b1592 JW5263 | nucleoid & integral IM protein (SEC in IM), Voltage-gated ClC-type chloride channel ClcB | Integral Inner Membrane, Nucleoid | PMID: 15919996 PMID: 23138451 | Integral Inner Membrane, Nucleoid | B, N | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 21 | 0.254 | TMH | 0 | 10.4168 | - | 10 | 9 | Y | n5-16c21/22o54-71i144-162o174-200i221-241o261-282i294-313o319-338i350-372o384-404i | CytoplasmicMembrane | 10 | 39 | ||||||
| YDGK_ECOLI | P76180 | ydgK | b1626 JW1618 | integral IM protein (SEC in IM), YdgK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 40 | 0.147 | TMH | 0 | 19.3259 | - | 4 | 4 | N | i12-36o56-78i90-108o114-133i | CytoplasmicMembrane | 10 | |||||||
| RSXD_ECOLI | P76182 | rsxD rnfD ydgO | rnfD ydgO | b1630 JW1622 | integral IM protein (SEC in IM), Ion-translocating oxidoreductase complex subunit D RsxD | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.191 | TMH | 0 | 5.44392 | - | 10 | 10 | N | i20-38o44-62i69-89o95-113i125-143o210-235i242-262o268-287i299-318o324-342i | CytoplasmicMembrane | 10 | ||||||||
| YDHJ_ECOLI | P76185 | ydhJ | b1644 JW1636 | integral IM protein (SEC in IM), YdhJ | Integral Inner Membrane | B | Bin | out/in | N/A | Membrane | Membrane anchored | SRP | SEC | yes | yes | N | 69 | 0.119 | TMH | 0 | 4.39451 | - | 1 | 1 | N | o6-26i | CytoplasmicMembrane | 9 | 26 | ||||||||
| YDHK_ECOLI | P76186 | ydhK | b1645 JW1637 | integral IM protein (SEC in IM), transporter YdhK | EchoLOCATION Signal peptide may be membrane anchored or cleaved and the protein therefore exported (signalP score near threshold) | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.119 | TMH | 0 | 4.68512 | - | 10 | 12 | N | i21-41o47-65i72-88o94-112i119-137o149-170i359-379o385-404i411-431o437-454i461-481o493-510i | CytoplasmicMembrane | 10 | ||||||||
| YDIM_ECOLI | P76197 | ydiM | b1690 JW1680 | integral IM protein (SEC in IM), transport YdiM | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 42 | 0.151 | TMH | 0 | 9.7669 | - | 12 | 12 | N | i12-30o42-62i74-90o96-112i133-156o162-183i204-227o247-268i275-292o298-325i337-359o365-385i | CytoplasmicMembrane | 10 | |||||||
| YDIN_ECOLI | P76198 | ydiN | b1691 JW5274 | integral IM protein (SEC in IM), transport YdiN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.235 | TMH | 0 | 11.6576 | - | 12 | 12 | N | i12-30o50-72i79-97o103-126i133-152o164-185i210-235o255-273i280-301o307-329i341-363o369-390i | CytoplasmicMembrane | 10 | |||||||
| YNIB_ECOLI | P76208 | yniB | b1726 JW1715 | integral IM protein (SEC in IM), YniB | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 44 | 0.107 | TMH | 0 | 5.0431 | - | 3 | 4 | N | o15-33i45-63o83-101i150-172o | CytoplasmicMembrane | 10 | 40 | ||||||||
| YDJX_ECOLI | P76219 | ydjX | b1750 JW1739 | integral IM protein (SEC in IM), of TVP38/TMEM64 family and DedA family, YdjX | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.175 | TMH | 0 | 13.2473 | - | 5 | 6 | N | i7-30o50-76i83-104o124-146i158-180o192-214i | CytoplasmicMembrane | 10 | ||||||
| YDJZ_ECOLI | P76221 | ydjZ | b1752 JW1741 | integral IM protein (SEC in IM), of TVP38/TMEM64 family and DedA family, YdjZ | Integral Inner Membrane | Member of the DedA family. DedA family proteins may play a more general role in membrane protein function or quality control and in maintenance of the PMF. | PMID: 15919996 PMID: 23086209 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.23 | TMH | 0 | 23.0428 | - | 5 | 5 | Y | n16-27c45/46o55-73i80-97o103-121i177-196o202-223i | CytoplasmicMembrane | 10 | ||||||
| YNJA_ECOLI | P76222 | ynjA | b1753 JW1742 | integral IM protein (SEC in IM), YnjA | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cytoplasmic | SRP | SEC | yes | yes | N | 26 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o33-51i | CytoplasmicMembrane | 9 | 41 | |||||||||
| YNJC_ECOLI | P76224 | ynjC | b1755 JW5285 | integral IM protein (SEC in IM), ABC transporter permease YnjC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 47 | 0.204 | TMH | 0 | 14.426 | - | 12 | 12 | N | i7-33o53-80i92-111o131-156i177-202o239-260i281-303o315-337i346-370o376-395i428-449o482-503i | CytoplasmicMembrane | 10 | |||||||
| YNJF_ECOLI | P76226 | ynjF | b1758 JW1747 | integral IM protein (SEC in IM), YnjF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 43 | 0.114 | CYT | 0 | -0.200913 | - | 5 | 5 | N | o33-60i81-102o114-135i147-167o173-195i | CytoplasmicMembrane | 10 | |||||||
| YNJI_ECOLI | P76228 | ynjI | b1762 JW5288 | integral IM protein (SEC in IM), YnjI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 58 | 0.169 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i42-64o70-91i | CytoplasmicMembrane | 10 | 4 | ||||||
| YDJK_ECOLI | P76230 | ydjK | b1775 JW5290 | integral IM protein (SEC in IM), Putative metabolite transport YdjK | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 43 | 0.144 | TMH | 0 | 3.8405 | - | 12 | 12 | N | i25-49o61-82i89-107o113-137i158-176o182-202i266-287o302-323i330-347o353-375i396-416o422-441i | CytoplasmicMembrane | 10 | |||||||
| CDGI_ECOLI | P76236 | cdgI yeaI | yeaI | b1785 JW1774 | integral IM protein (SEC in IM), Probable diguanylate cyclase CdgI | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 56 | 0.137 | CYT | 0 | -0.200913 | - | 8 | 8 | N | i58-76o88-110i122-143o163-182i194-215o235-257i269-287o293-318i | CytoplasmicMembrane | 10 | ||||||
| DGCJ_ECOLI | P76237 | dgcJ yeaJ | yeaJ | b1786 JW5291 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.176 | SpI | 30 | 1.61892 | - | 2 | 1 | Y | n11-26c31/32o305-327i | CytoplasmicMembrane | 9 | 15 | |||||
| YOAI_ECOLI | P76239 | yoaI | b1788 JW5885 | integral IM protein (SEC in IM), YoaI | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Membrane | - | SRP | SEC | no | yes | N | 21 | 0.164 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-30i | CytoplasmicMembrane | 9 | |||||||||
| NIMT_ECOLI | P76242 | nimT yeaN | yeaN | b1791 JW1780 | integral IM protein (SEC in IM), 2-nitroimidazole transporter NimT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.135 | TMH | 0 | 4.63339 | - | 12 | 12 | N | i12-37o49-70i82-98o104-126i138-160o166-185i212-239o251-270i279-299o305-323i335-355o367-387i | CytoplasmicMembrane | 10 | ||||||
| LEUE_ECOLI | P76249 | leuE yeaS | yeaS | b1798 JW1787 | integral IM protein (SEC in IM), Leucine efflux protein LeuE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 47 | 0.141 | TMH | 0 | 12.792 | - | 6 | 6 | N | o12-32i44-69o81-99i120-142o154-179i191-209o | CytoplasmicMembrane | 10 | ||||||
| PDED_ECOLI | P76261 | pdeD adrB yoaD | adrB yoaD | b1815 JW1804 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeD | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 29 | 0.12 | SpI | 35 | 1.97681 | - | 1 | 1 | Y | n17-27c32/33o245-265i | CytoplasmicMembrane | 7 | 13 | |||||||
| MNTP_ECOLI | P76264 | mntP yebN | yebN | b1821 JW5830 | integral IM protein (SEC in IM), Probable manganese efflux pump MntP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | Y | 20 | 0.786 | SpI | 19 | 8.81356 | - | 5 | 4 | Y | n3-11c19/20o68-86i106-127o133-154i166-186o | CytoplasmicMembrane | 10 | ||||||
| YEBQ_ECOLI | P76269 | yebQ | b1828 JW5299 | integral IM protein (SEC in IM), transporter YebQ | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 49 | 0.145 | TMH | 0 | 3.99006 | - | 12 | 14 | N | i15-34o54-74i86-107o113-133i145-167o173-191i203-225o231-249i269-295o307-328i335-357o363-379i400-420o432-451i | CytoplasmicMembrane | 10 | |||||||||
| YEBT_ECOLI | P76272 | yebT | b1834 JW1823 | integral IM protein (SEC in IM), Intertransport YebT | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 47 | 0.12 | TMH | 0 | 4.96376 | - | 1 | 1 | N | i21-39o | Unknown | 2 | 30 | ||||||||
| YEBZ_ECOLI | P76278 | yebZ | b1840 JW1829 | integral IM protein (SEC in IM), YebZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 31 | 0.14 | TMH | 0 | 12.9484 | - | 8 | 8 | N | o6-29i50-73o93-111i118-138o150-171i192-215o227-248i269-287o | CytoplasmicMembrane | 10 | |||||||
| FLHA_ECOLI | P76298 | flhA | b1879 JW1868 | integral IM protein (SEC in IM), biosynthesis FlhA | Integral Inner Membrane | Part of FlgN-FlgK-FliJ-FlhA complex. | PMID: 15919996 PMID: 22233518 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.137 | TMH | 0 | 10.1028 | - | 7 | 8 | N | i21-40o46-65i77-97o117-140i209-231o251-273i285-305o311-327i | CytoplasmicMembrane | 10 | 14 | |||||
| FLHB_ECOLI | P76299 | flhB yecQ | yecQ | b1880 JW1869 | integral IM protein (SEC in IM), biosynthetic FlhB | Integral Inner Membrane | Regulates ordered export of flagellar components via autocleavage mechanism. | PMID: 15919996 PMID: 16246842 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 54 | 0.142 | CYT | 0 | -0.200913 | - | 4 | 4 | N | i35-53o88-115i145-168o188-213i | CytoplasmicMembrane | 10 | |||||
| DGCQ_ECOLI | P76330 | dgcQ yedQ | yedQ | b1956 JW5832 | integral IM protein (SEC in IM), Probable diguanylate cyclase DgcQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 44 | 0.109 | TMH | 0 | 0.725864 | - | 2 | 2 | N | i21-42o358-380i | Cytoplasmic | 9 | 12 | |||||
| YEDR_ECOLI | P76334 | yedR | b1963 JW1946 | integral IM protein (SEC in IM), YedR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 23 | 0.118 | TMH | 0 | 0.40092 | - | 2 | 3 | N | o6-22i43-62o86-109i | CytoplasmicMembrane | 10 | 43 | ||||||
| YEDV_ECOLI | P76339 | yedV | b1968 JW1951 | integral IM protein (SEC in IM), Sensor histidine kinase YedV | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 24 | 0.26 | TMH | 0 | 7.43701 | - | 2 | 1 | Y | n10-18c23/24o159-180i | CytoplasmicMembrane | 10 | 12 | ||||||
| MSRQ_ECOLI | P76343 | msrQ yedZ | yedZ | b1972 JW1955 | integral IM protein (SEC in IM), Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ | Integral Inner Membrane | Is attached to the inner membrane when interacting with the YedZ subunit. | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.146 | TMH | 0 | 6.8144 | - | 6 | 6 | N | i9-30o50-68i80-98o118-138i150-167o173-191i | CytoplasmicMembrane | 10 | |||||
| C56H_ECOLI | P76345 | yodB | b1974 JW5323 | integral IM protein (SEC in IM), Cytochrome b561 homolog 1 YodB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 25 | 0.146 | TMH | 0 | 8.67869 | - | 4 | 4 | N | i9-26o46-63i84-108o144-162i | CytoplasmicMembrane | 10 | 15 | ||||||
| SHIA_ECOLI | P76350 | shiA yeeM | yeeM | b1981 JW1962 | integral IM protein (SEC in IM), Shikimate transporter ShiA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.125 | TMH | 0 | 0.821024 | - | 12 | 12 | N | i25-49o61-84i96-114o120-139i160-184o196-215i256-276o288-310i317-336o342-363i383-408o414-432i | CytoplasmicMembrane | 10 | 3 | |||||
| YEEO_ECOLI | P76352 | yeeO | b1985 JW1965 | integral IM protein (SEC in IM), Probable FMN/FAD exporter YeeO | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 30 | 0.152 | CYT | 0 | -0.200913 | - | 11 | 12 | N | i45-71o83-105i117-140o160-180i192-216o222-247i268-289o309-332i352-375o387-408i420-440o446-468i | CytoplasmicMembrane | 10 | |||||||
| YEER_ECOLI | P76361 | yeeR | b2001 JW1983 | integral IM protein (SEC in IM), YeeR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene), pseudogene (Ochman & Davalos, 2006) | no | no | N | 34 | 0.25 | TMH | 0 | 5.74833 | - | 6 | 6 | N | i7-26o32-50i62-81o96-115i135-159o165-185i | CytoplasmicMembrane | 10 | 9 | |||||
| WZZB_ECOLI | P76372 | wzzB cld rol wzz | cld rol wzz | b2027 JW5836 | integral IM protein (SEC in IM), Chain length determinant WzzB | Integral Inner Membrane | PMID: 15919996 PMID: 16079137 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 53 | 0.174 | CYT | 0 | -0.200913 | - | 2 | 2 | N | o32-51i296-316o | CytoplasmicMembrane | 10 | 8 | |||||
| WZC_ECOLI | P76387 | wzc | b2060 JW2045 | integral IM protein (SEC in IM), Tyrosine-kinase wzc Wzc | Integral Inner Membrane | Prediction of one very weak transmembrane region. | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 58 | 0.141 | CYT | 0 | -0.200913 | - | 2 | 2 | N | o32-51i426-449o | CytoplasmicMembrane | 10 | 19 | |||||
| YEGH_ECOLI | P76389 | yegH | b2063 JW5336 | integral IM protein (SEC in IM), UPF0053 YegH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 64 | 0.117 | TMH | 0 | 2.5813 | - | 7 | 7 | N | o12-34i46-68o88-105i125-148o154-172i184-207o213-233i | CytoplasmicMembrane | 10 | 16 | ||||||
| YEGI_ECOLI | P76393 | yegI | b2070 JW2055 | integral IM protein (SEC in IM), kinase YegI | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cytoplasmic | SRP | SEC | no | yes | N | 52 | 0.148 | CYT | 0 | -0.200913 | - | 0 | 2 | N | i393-413o419-438i | Cytoplasmic | 8 | ||||||||||
| MDTB_ECOLI | P76398 | mdtB yegN | yegN | b2075 JW2060 | integral IM protein (SEC in IM), Multidrug resistance MdtB | Integral Inner Membrane | Part of MdtABC-TolC multidrug efflux transport system = [(TolC)3][MdtC][MdtB][MdtA]. References: | PMID: 12107133 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.132 | TMH | 0 | 4.88895 | - | 11 | 12 | N | i21-41o345-362i369-389o395-416i437-460o472-496i537-557o867-885i892-912o918-944i965-984o996-1022i | CytoplasmicMembrane | 10 | |||||
| MDTC_ECOLI | P76399 | mdtC yegO | yegO | b2076 JW2061 | integral IM protein (SEC in IM), Multidrug resistance MdtC | Integral Inner Membrane | Part of MdtABC-TolC multidrug efflux transport system = [(TolC)3][MdtC][MdtB][MdtA]. | PMID: 12107133 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 61 | 0.131 | TMH | 0 | 7.90298 | - | 10 | 12 | N | i12-32o336-353i360-384o390-410i431-451o463-490i528-545o853-871i878-895o901-917i953-970o982-1008i | CytoplasmicMembrane | 10 | |||||
| YEGT_ECOLI | P76417 | yegT | b2098 JW2085 | integral IM protein (SEC in IM), Putative nucleoside transporter YegT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 36 | 0.176 | TMH | 0 | 11.594 | - | 12 | 12 | N | i7-29o41-58i70-86o98-120i132-152o164-182i211-232o244-262i274-294o300-325i337-356o376-400i | CytoplasmicMembrane | 10 | |||||||
| YEGX_ECOLI | P76421 | yegX | b2102 JW5345 | integral IM protein (SEC in IM), YegX | Belongs to the glycosyl hydrolase 25 family; Glycoside hydrolase family 25 GH25 comprises enzymes with only one known activity;Lysozyme (EC:3.2.1.17). So we expect this to be acting on the peptidoglycan and therefore facing periplasm. | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | yes | yes | N | 28 | 0.118 | TMH | 0 | 7.43323 | - | 1 | 0 | Y | n11-21c25/26o | Unknown | 2 | 31 | ||||||||
| RCNA_ECOLI | P76425 | rcnA yohM | yohM | b2106 JW2093 | nucleoid & integral IM protein (SEC in IM), Nickel/cobalt efflux system RcnA | Integral Inner Membrane, Nucleoid | PMID: 15805538 PMID: 15919996 | Integral Inner Membrane, Nucleoid | B, N | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 40 | 0.135 | TMH | 0 | 8.07836 | - | 6 | 6 | N | o12-31i52-77o89-107i173-196o202-230i251-273o | CytoplasmicMembrane | 10 | ||||||
| LPXT_ECOLI | P76445 | lpxT yeiU | yeiU | b2174 JW2162 | integral IM protein (SEC in IM), Lipid A 1-diphosphate synthase LpxT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.122 | TMH | 0 | 7.40709 | - | 5 | 5 | N | i7-24o63-81i93-113o161-182i191-212o | CytoplasmicMembrane | 10 | 35 | |||||
| PDEN_ECOLI | P76446 | pdeN rtn | rtn | b2176 JW2164 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 31 | 0.108 | TMH | 0 | 2.52515 | - | 2 | 2 | N | i12-36o236-258i | CytoplasmicMembrane | 10 | 76 | |||||
| ATOE_ECOLI | P76460 | atoE | b2223 JW2217 | integral IM protein (SEC in IM), Putative short-chain fatty acid transporter AtoE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 36 | 0.138 | TMH | 0 | 16.8697 | - | 9 | 9 | N | o20-38i54-75o95-124i136-162o182-201i245-263o269-286i298-316o418-439i | CytoplasmicMembrane | 10 | |||||||
| RHMT_ECOLI | P76470 | rhmT yfaV | yfaV | b2246 JW2240 | integral IM protein (SEC in IM), transport RhmT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 39 | 0.245 | TMH | 0 | 3.16424 | - | 12 | 11 | Y | n17-30c38/39o54-75i82-101o107-129i141-163o175-197i240-261o273-295i307-326o332-350i362-383o395-415i | CytoplasmicMembrane | 10 | ||||||
| ARNT_ECOLI | P76473 | arnT pmrK yfbI | pmrK yfbI | b2257 JW2251 | integral IM protein (SEC in IM), Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase ArnT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 29 | 0.116 | TMH | 0 | 5.33485 | - | 12 | 12 | N | i7-28o81-103i110-131o137-153i165-192o204-227i257-278o290-308i315-335o347-367i379-400o406-425i | CytoplasmicMembrane | 10 | ||||||
| ARNF_ECOLI | P76474 | arnF pmrM yfbJ | pmrM yfbJ | b2258 JW5373 | integral IM protein (SEC in IM), Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 24 | 0.127 | TMH | 0 | 10.9868 | - | 4 | 3 | Y | n7-18c23/24o47-65i77-97o103-121i | CytoplasmicMembrane | 10 | 9 | |||||
| YFBL_ECOLI | P76482 | yfbL | b2271 JW2266 | integral IM protein (SEC in IM), YfbL | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane | Membrane anchored | SRP | SEC | no | yes | N | 37 | 0.316 | TMH | 0 | 1.10045 | - | 1 | 0 | Y | n4-16c28/29o | CytoplasmicMembrane | 9 | |||||||||
| YFDI_ECOLI | P76507 | yfdI | b2352 JW5382 | integral IM protein (SEC in IM), YfdI | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 20 | 0.145 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i7-25o71-90i97-115o121-139i146-163o169-194i206-226o354-373i380-398o410-429i | CytoplasmicMembrane | 10 | ||||||||
| YFDY_ECOLI | P76521 | yfdY | b2377 JW2374 | integral IM protein (SEC in IM), YfdY | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 28 | 0.123 | TMH | 0 | 19.5928 | - | 3 | 3 | N | o6-25i32-49o55-75i | CytoplasmicMembrane | 10 | 58 | ||||||||
| YFEZ_ECOLI | P76538 | yfeZ | b2433 JW2426 | integral IM protein (SEC in IM), YfeZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.118 | TMH | 0 | 1.95358 | - | 4 | 4 | N | i21-41o61-78i90-110o116-135i | CytoplasmicMembrane | 10 | 40 | ||||||
| EUTH_ECOLI | P76552 | eutH yffU | yffU | b2452 JW2436 | integral IM protein (SEC in IM), Ethanolamine utilization EutH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 70 | 0.135 | TMH | 0 | 5.16844 | - | 10 | 9 | N | o6-24i57-84o120-146i153-178o190-215i227-250o270-294i342-364o370-392i | CytoplasmicMembrane | 10 | ||||||
| YFGM_ECOLI | P76576 | yfgM | b2513 JW2497 | integral IM protein (SEC in IM), UPF0070 YfgM | Integral Inner Membrane | Periplasmic chaperone. Periplasmic chaperone which associates with PpiD and the SecYEG translocon and operates in a network that contains Skp and SurA. Potential substrates identified are nine inner membrane proteins (CusS, EvgS, MalF, OsmC, TdcB, TdcC, WrbA, YfhB, and YtfH) and seven periplasmic proteins (HdeA, HdeB, AnsB, Ggt, MalE, YcgK, and YnjE). PMID: 25403562 Periplasmic chaperone YfgM associates with PpiD and the SecYEG translocon and operates in a network that contains Skp and SurA. PMID: 25403562 | PMID: 21210718 PMID: 24855643 PMID: 25403562 | Integral Inner Membrane | B | Bout | in/out | IM (predicted), Detected in IM Fraction | Membrane | Membrane anchored | SRP | SEC | yes | yes | N | 27 | 0.142 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i24-42o | Periplasmic | 9 | 50 | |||||
| PBPC_ECOLI | P76577 | pbpC yfgN | yfgN | b2519 JW2503 | integral IM protein (SEC in IM), Penicillin-binding 1C PbpC | Integral Inner Membrane | Cell wall biogenesis. Peptidoglycan biosynthesis. PMID: 10542235 | PMID: 10542235 | Integral Inner Membrane | B | Bout | in/out | N/A | Cell inner membrane | Membrane anchored (Experimental) | SRP | SEC | no | yes | N | 28 | 0.288 | SpI | 27 | 10.5085 | - | 1 | 0 | Y | n10-23c27/28o | CytoplasmicMembrane | 10 | 8 | ||||
| YGAY_ECOLI | P76628 | ygaY | b2681 JW2655 b2680 | integral IM protein (SEC in IM), Putative transporter YgaY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | N | 31 | 0.333 | TMH | 0 | 8.33787 | - | 10 | 12 | N | i12-30o42-66i78-96o102-123i135-154o166-185i217-239o245-264i276-294o300-318i339-359o365-384i | CytoplasmicMembrane | 10 | 11 | |||||
| YGAZ_ECOLI | P76630 | ygaZ | b2682 JW2657 | integral IM protein (SEC in IM), YgaZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 36 | 0.194 | TMH | 0 | 4.25735 | - | 5 | 6 | N | o22-39i51-70o76-94i140-163o175-193i205-238o | CytoplasmicMembrane | 10 | |||||||
| YQIJ_ECOLI | P76657 | yqiJ | b3050 JW3022 | integral IM protein (SEC in IM), YqiJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 39 | 0.125 | TMH | 0 | 3.14983 | - | 3 | 3 | N | i12-35o66-86i98-117o | CytoplasmicMembrane | 10 | 12 | ||||||
| YZGL_ECOLI | P76692 | yzgL | b3427 JW3390 | integral IM protein (SEC in IM), YzgL | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | no | no | N | 23 | 0.127 | TMH | 0 | 17.4708 | - | 2 | 2 | N | i12-40o46-69i | CytoplasmicMembrane | 10 | 29 | ||||||||
| YQCE_ECOLI | P77031 | yqcE yqcF | yqcF | b2775 JW2746 | integral IM protein (SEC in IM), YqcE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.15 | TMH | 0 | 12.03 | - | 12 | 12 | N | i12-32o47-65i77-93o99-121i142-160o172-193i214-240o260-280i292-310o316-338i350-371o391-409i | CytoplasmicMembrane | 10 | ||||||
| HOKE_ECOLI | P77091 | hokE ybdY | ybdY | b4415 JW5084 | integral IM protein (SEC in IM), Toxic HokE | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 20 | 0.132 | SpI | 24 | 2.84692 | - | 1 | 0 | Y | n6-24c29/30o | Periplasmic | 9 | 51 | ||||
| YDCU_ECOLI | P77156 | ydcU | b1442 JW1437 | integral IM protein (SEC in IM), ABC transporter permease YdcU | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 42 | 0.107 | TMH | 0 | 17.0809 | - | 8 | 7 | N | i29-53o86-110i122-143o155-176i188-207o236-258i279-303o | CytoplasmicMembrane | 10 | |||||||
| PDEF_ECOLI | P77172 | pdeF yfgF | yfgF | b2503 JW2488 | integral IM protein (SEC in IM), Cyclic di-GMP phosphodiesterase PdeF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 64 | 0.246 | TMH | 0 | 18.0434 | - | 9 | 9 | N | o14-32i44-74o86-106i126-149o169-187i216-235o241-258i265-285o297-316i | CytoplasmicMembrane | 10 | ||||||
| ZIPA_ECOLI | P77173 | zipA | b2412 JW2404 | integral IM protein (SEC in IM), Cell division ZipA | Integral Inner Membrane | Has been purified as a complex with ZipA-EptA. PMID: 9008158 | PMID: 16079137 PMID: 9008158 | Integral Inner Membrane | B | Bout | in/out | Soluble IM Fraction | Cell inner membrane | Periplasmic with N-terminal membrane anchor (Experimental) | SRP | SEC | yes | yes | N | 25 | 0.169 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i7-26o | CytoplasmicMembrane | 10 | 96 | |||||
| RSXE_ECOLI | P77179 | rsxE rnfE ydgQ | rnfE ydgQ | b1632 JW1624 | integral IM protein (SEC in IM), Ion-translocating oxidoreductase complex subunit E RsxE | Integral Inner Membrane | PMID: 15919996 PMID: 24688744 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 38 | 0.173 | CYT | 0 | -0.200913 | - | 5 | 6 | N | i12-32o38-57i69-87o93-113i125-148o183-206i | CytoplasmicMembrane | 10 | 3 | |||||
| YKGH_ECOLI | P77180 | ykgH | b0310 JW0302 | integral IM protein (SEC in IM), YkgH | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 45 | 0.104 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i21-42o186-209i | Unknown | 2 | 25 | ||||||||
| YAHC_ECOLI | P77219 | yahC | b0317 JW0309 | integral IM protein (SEC in IM), YahC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 70 | 0.119 | TMH | 0 | 10.9451 | - | 4 | 5 | Y | n4-15c23/24o33-49i61-80o86-104i109-127o133-152i | CytoplasmicMembrane | 10 | |||||||
| YDFJ_ECOLI | P77228 | ydfJ | b4600 JW1536 b1543 | integral IM protein (SEC in IM), Putative transporter YdfJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | yes | no | N | 26 | 0.241 | TMH | 0 | 3.5335 | - | 9 | 11 | N | o25-49i61-79o85-105i126-152o158-180i223-242o254-273i280-301o307-328i348-368o374-394i | CytoplasmicMembrane | 10 | ||||||
| ESSQ_ECOLI | P77237 | essQ ydfS | ydfS | b1556 JW5255 | integral IM protein (SEC in IM), Prophage lysis S homolog EssQ | Integral Inner Membrane | B | Binout | in/in | IM (predicted) | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | yes | no | N | 38 | 0.166 | CYT | 0 | -0.200913 | - | 2 | 1 | Y | n7-15c20/21o36-58i | Unknown | 2 | 17 | |||||||
| MDLA_ECOLI | P77265 | mdlA mdl | mdl | b0448 JW0438 | integral IM protein (SEC in IM), Multidrug resistance-like ATP-binding MdlA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 41 | 0.117 | TMH | 0 | 9.77173 | - | 6 | 5 | Y | n19-31c40/41o56-77i127-150o156-175i248-268o280-301i | CytoplasmicMembrane | 10 | 9 | |||||
| PTYBC_ECOLI | P77272 | murP yfeV | yfeV | b2429 JW2422 | integral IM protein (SEC in IM), PTS system N-acetylmuramic acid-specific EIIBC component MurP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 27 | 0.108 | CYT | 0 | -0.200913 | - | 10 | 10 | N | i113-144o164-182i194-215o227-244i256-283o303-326i335-355o367-387i394-416o445-468i | CytoplasmicMembrane | 10 | ||||||
| GTRB_ECOLI | P77293 | yfdH | b2351 JW2347 | integral IM protein (SEC in IM), Prophage bactoprenol glucosyl transferase homolog YfdH | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene), pseudogene (Ochman & Davalos, 2006) | no | no | N | 47 | 0.115 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i228-249o261-286i | CytoplasmicMembrane | 10 | ||||||
| DTPA_ECOLI | P77304 | dtpA tppB ydgR | tppB ydgR | b1634 JW1626 | integral IM protein (SEC in IM), Dipeptide and tripeptide permease A DtpA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 19 | 0.114 | CYT | 0 | -0.200913 | - | 14 | 14 | N | i21-40o60-81i90-107o113-131i152-173o179-199i220-239o245-264i276-295o323-341i353-371o391-411i423-444o456-477i | CytoplasmicMembrane | 10 | ||||||
| YQIK_ECOLI | P77306 | yqiK | b3051 JW3023 | integral IM protein (SEC in IM) with Band 7/SPFH domain, YqiK | Integral Inner Membrane | Fluorescent fusions of YqiK have been monitored via fluorescence microscopy. YqiK was found to be distributed diffusely throughout cytoplasm. | PMID: 15919996 PMID: 17272300 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Single-pass membrane protein | Membrane anchored | SRP | SEC | no | yes | N | 31 | 0.212 | TMH | 0 | 10.6089 | - | 2 | 2 | N | o12-32i52-72o | CytoplasmicMembrane | 10 | 101 | |||||
| FETB_ECOLI | P77307 | fetB ybbM | ybbM | b0491 JW5066 | integral IM protein (SEC in IM), Probable iron export permease FetB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.145 | CYT | 0 | -0.200913 | - | 7 | 7 | N | o6-24i36-57o63-79i91-112o118-142i191-209o215-241i | CytoplasmicMembrane | 10 | 26 | |||||
| DDPB_ECOLI | P77308 | ddpB yddR | yddR | b1486 JW1481 | integral IM protein (SEC in IM), Probable D,D-dipeptide transport system permease DdpB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 42 | 0.124 | TMH | 0 | 8.66848 | - | 7 | 7 | N | i12-32o103-124i136-158o204-223i244-267o273-294i306-330o | CytoplasmicMembrane | 10 | ||||||
| YPHD_ECOLI | P77315 | yphD | b2546 JW2530 | integral IM protein (SEC in IM), Probable ABC transporter permease YphD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 45 | 0.178 | TMH | 0 | 0.0658844 | - | 8 | 10 | N | i27-50o56-74i81-98o104-124i131-152o172-192i224-245o251-271i278-300o306-323i | CytoplasmicMembrane | 10 | 37 | ||||||
| YBBY_ECOLI | P77328 | ybbY glxB4 | glxB4 | b0513 JW0501 | integral IM protein (SEC in IM), Putative purine permease YbbY | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 63 | 0.155 | TMH | 0 | 7.37862 | - | 12 | 12 | Y | n11-23c35/36o45-64i76-93o99-122i129-151o171-190i197-217o237-260i281-300o320-341i353-371o377-396i408-427o | CytoplasmicMembrane | 10 | ||||||
| MSCK_ECOLI | P77338 | mscK aefA kefA | aefA kefA | b0465 JW0454 | integral IM protein (SEC in IM), Mechanosensitive channel MscK | Integral Inner Membrane | PMID: 11985727 PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | Y | 34 | 0.323 | SpII | 26 | 9.75259 | Pos+2=Q | 12 | 11 | Y | n14-27c35/36o499-522i560-579o585-606i630-646o658-679i691-716o728-747i796-820o840-860i881-902o914-942i | CytoplasmicMembrane | 10 | ||||||
| YAFU_ECOLI | P77354 | yafU | b0218 JW0207 | integral IM protein (SEC in IM), Putative YafU | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | no | no | N | 39 | 0.16 | TMH | 0 | 1.65262 | - | 2 | 2 | N | i21-38o44-64i | CytoplasmicMembrane | 10 | 73 | |||||
| DJLC_ECOLI | P77359 | djlC ybeV | ybeV | b0649 JW0644 | integral IM protein (SEC in IM), J domain-containing DjlC | Integral Inner Membrane | Hsc56 (DjlC) is a DnaJ-like protein that activates the ATPase activity of Hsc62. Hsc56 has a region that may constitute a transmembrane segment PMID: 12183460 | PMID: 12183460 | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Cytoplasmic | SRP | SEC | no | yes | N | 60 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o464-482i | Cytoplasmic | 8 | ||||||
| WZXC_ECOLI | P77377 | wzxC wzx | wzx | b2046 JW2031 | integral IM protein (SEC in IM), polysaccharide biosynthesis WzxC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 34 | 0.17 | TMH | 0 | 3.47452 | - | 12 | 12 | N | i12-36o42-67i79-99o111-128i149-167o173-191i289-308o320-340i361-379o385-402i414-439o445-467i | CytoplasmicMembrane | 10 | ||||||
| DJLB_ECOLI | P77381 | djlB ybeS | ybeS | b0646 JW0641 | integral IM protein (SEC in IM), J domain-containing DjlB | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Membrane anchored | SRP | SEC | no | yes | N | 32 | 0.105 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o456-474i | Cytoplasmic | 8 | 63 | ||||||||
| YDHP_ECOLI | P77389 | ydhP | b1657 JW1649 | integral IM protein (SEC in IM), transport YdhP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 53 | 0.146 | TMH | 0 | 3.82773 | - | 12 | 11 | Y | n7-16c34/35o44-64i71-89o101-122i129-152o158-180i201-224o236-257i269-287o293-311i331-349o355-374i | CytoplasmicMembrane | 10 | |||||||
| YBAT_ECOLI | P77400 | ybaT | b0486 JW0475 | integral IM protein (SEC in IM), transport YbaT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 66 | 0.222 | TMH | 0 | 20.3109 | - | 12 | 12 | N | i12-35o47-65i85-109o129-146i158-179o191-209i229-249o278-304i325-343o349-368i380-400o406-424i | CytoplasmicMembrane | 10 | |||||||
| YDHU_ECOLI | P77409 | ydhU | b1670 JW1660 | integral IM protein (SEC in IM), Putative cytochrome YdhU | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 8 | 0.115 | TMH | 0 | 1.01731 | - | 5 | 5 | N | o26-50i75-97o109-132i182-206o218-240i | CytoplasmicMembrane | 10 | 10 | ||||||||
| HYFD_ECOLI | P77416 | hyfD | b2484 JW2469 | integral IM protein (SEC in IM), Hydrogenase-4 component D HyfD | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 28 | 0.57 | SpI | 27 | 6.08873 | - | 12 | 14 | Y | n4-15c20/21o30-50i55-74o80-101i113-131o137-156i168-188o208-230i242-261o267-287i299-320o332-352i364-389o409-431i458-478o | CytoplasmicMembrane | 10 | |||||||
| HYFF_ECOLI | P77437 | hyfF | b2486 JW2471 | integral IM protein (SEC in IM), Hydrogenase-4 component F HyfF | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 24 | 0.427 | TMH | 0 | 3.63797 | - | 12 | 13 | N | o6-24i36-54o74-95i107-130o136-156i168-188o217-242i254-276o288-306i326-345o379-397i418-437o457-475i | CytoplasmicMembrane | 10 | |||||||
| DDPC_ECOLI | P77463 | ddpC yddQ | yddQ | b1485 JW1480 | integral IM protein (SEC in IM), Probable D,D-dipeptide transport system permease DdpC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 55 | 0.251 | TMH | 0 | 9.04769 | - | 5 | 6 | N | i32-54o97-121i128-150o156-174i218-240o260-282i | CytoplasmicMembrane | 10 | 15 | |||||
| PDEB_ECOLI | P77473 | pdeB ylaB | ylaB | b0457 JW5062 | integral IM protein (SEC in IM), Probable cyclic di-GMP phosphodiesterase PdeB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 32 | 0.21 | CYT | 0 | -0.200913 | - | 2 | 1 | Y | n6-20c25/26o243-265i | CytoplasmicMembrane | 7 | 8 | |||||
| CUSS_ECOLI | P77485 | cusS ybcZ | ybcZ | b0570 JW5082 | integral IM protein (SEC-YidC in IM), Sensor histidine kinase CusS | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. Potential substrate of periplasmic chaperone YfgM. PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 15919996 PMID: 22108384 PMID: 25403562 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | YfgM | yes | yes | N | 27 | 0.187 | SpI | 32 | 6.24017 | - | 2 | 2 | N | i12-36o187-206i | CytoplasmicMembrane | 10 | 15 | |||
| HOKB_ECOLI | P77494 | hokB ydcB | ydcB | b4428 JW5225 | integral IM protein (SEC in IM), Toxic HokB | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Bin | out/in | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 26 | 0.105 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-24i | Periplasmic | 9 | 42 | ||||
| YBBP_ECOLI | P77504 | ybbP | b0496 JW0485 | integral IM protein (SEC in IM), ABC transporter permease YbbP | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 32 | 0.226 | TMH | 0 | 5.99165 | - | 10 | 9 | Y | n15-26c31/32o243-263i295-317o337-356i377-397o403-429i450-473o683-702i723-747o767-790i | CytoplasmicMembrane | 10 | 75 | ||||||||
| YBDJ_ECOLI | P77506 | ybdJ | b0580 JW0569 | integral IM protein (SEC in IM), YbdJ | Integral Inner Membrane | B | Binout | in/in | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 36 | 0.165 | TMH | 0 | 13.1416 | - | 2 | 1 | Y | n7-25c33/34o49-70i | CytoplasmicMembrane | 9 | |||||||||
| DPIB_ECOLI | P77510 | dpiB citA mpdB ybeP | citA mpdB ybeP | b0619 JW0611 | integral IM protein (SEC-YidC in IM), Sensor histidine kinase DpiB | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 36 | 0.245 | TMH | 0 | 4.47899 | - | 2 | 2 | N | i20-41o179-202i | CytoplasmicMembrane | 10 | |||||
| YDJN_ECOLI | P77529 | ydjN | b1729 JW1718 | integral IM protein (SEC in IM), L-cystine transporter YdjN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted), Detected in IM Fraction | Cell membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 21 | 0.243 | SpI | 20 | 3.32787 | - | 9 | 11 | N | o6-22i34-51o71-92i104-126o186-205i225-245o265-284i296-313o333-358i370-389o395-415i | CytoplasmicMembrane | 10 | 9 | ||||||
| YFHR_ECOLI | P77538 | yfhR | b2534 JW2518 | integral IM protein (SEC in IM), YfhR | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Membrane | Membrane anchored | SRP | SEC | yes | yes | N | 21 | 0.132 | TMH | 0 | 7.32949 | - | 1 | 1 | N | i12-36o | CytoplasmicMembrane | 9 | 20 | ||||||||
| PRPB_ECOLI | P77541 | prpB yahQ | yahQ | b0331 JW0323 | integral IM protein (SEC in IM), 2-methylisocitrate lyase PrpB | Integral Inner Membrane | One weak transmembrane region prediction. | PMID: 12706720 | Integral Inner Membrane | B | - | IM (predicted-detected) | Cytoplasmic | SRP | SEC | no | yes | N | 51 | 0.142 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 33 | ||||||
| YFCJ_ECOLI | P77549 | yfcJ | b2322 JW2319 | integral IM protein (SEC in IM), MFS-type transporter YfcJ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 45 | 0.121 | TMH | 0 | 9.50937 | - | 12 | 12 | N | i20-42o48-66i87-106o112-138i150-171o177-198i210-243o249-269i281-299o305-328i340-359o365-389i | CytoplasmicMembrane | 10 | |||||||
| PTFC1_ECOLI | P77579 | fryC ypdG | ypdG | b2386 JW2383 | integral IM protein (SEC in IM), Fructose-like permease IIC component 1 FryC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.15 | SpI | 19 | 5.67099 | - | 10 | 9 | Y | n7-14c19/20o43-68i95-119o160-178i190-216o239-256i277-297o317-335i342-361o381-402i | CytoplasmicMembrane | 10 | ||||||
| MHPT_ECOLI | P77589 | mhpT yaiK | yaiK | b0353 JW5046 | integral IM protein (SEC in IM), 3-(3-hydroxy-phenyl)propionate transporter MhpT | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.177 | TMH | 0 | 11.0732 | - | 12 | 11 | Y | n15-26c44/45o54-74i81-101o107-128i140-163o169-189i209-235o255-273i280-300o306-328i340-359o371-391i | CytoplasmicMembrane | 10 | ||||||
| YAGL_ECOLI | P77607 | yagL | b0278 JW0272 | integral IM protein (SEC in IM), YagL | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cytoplasmic | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 32 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i12-32o | Cytoplasmic | 8 | 13 | ||||||||
| ANSP_ECOLI | P77610 | ansP yncF | yncF | b1453 JW5234 | integral IM protein (SEC-YidC in IM), L-asparagine permease AnsP | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 15919996 PMID: 22108384 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC-YidC | yes | yes | N | 65 | 0.134 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i37-56o62-86i107-133o145-167i174-194o214-239i260-282o302-330i351-374o380-403i424-442o448-468i | CytoplasmicMembrane | 10 | |||||
| LSRC_ECOLI | P77672 | lsrC ydeY | ydeY | b1514 JW1507 | integral IM protein (SEC in IM), Autoinducer 2 import system permease LsrC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 30 | 0.13 | TMH | 0 | 7.11134 | - | 9 | 7 | Y | n12-23c29/30o39-60i72-105o111-135i155-178o208-232i244-271o291-309i | CytoplasmicMembrane | 10 | ||||||
| GTRA_ECOLI | P77682 | yfdG | b2350 JW2346 | integral IM protein (SEC in IM), Prophage bactoprenol-linked glucose translocase homolog YfdG | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | no | no | N | 38 | 0.341 | TMH | 0 | 11.761 | - | 4 | 4 | N | i12-30o36-55i67-85o91-110i | CytoplasmicMembrane | 10 | ||||||
| YCJP_ECOLI | P77716 | ycjP | b1312 JW1305 | integral IM protein (SEC in IM), ABC transporter permease YcjP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 40 | 0.318 | TMH | 0 | 14.4011 | - | 7 | 6 | N | i12-36o78-100i112-139o145-165i186-211o243-264i | CytoplasmicMembrane | 10 | |||||||
| YAJR_ECOLI | P77726 | yajR | b0427 JW5059 | integral IM protein (SEC in IM), transport YajR | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 37 | 0.111 | TMH | 0 | 13.9587 | - | 12 | 12 | N | i21-42o48-68i80-98o104-124i136-158o164-186i217-240o252-273i280-296o302-319i340-361o367-388i | CytoplasmicMembrane | 10 | |||||||
| FOCB_ECOLI | P77733 | focB | b2492 JW2477 | integral IM protein (SEC in IM), Probable formate transporter 2 FocB | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 46 | 0.177 | CYT | 0 | -0.200913 | - | 6 | 6 | N | i34-56o68-89i109-133o164-182i194-222o254-276i | CytoplasmicMembrane | 10 | 74 | ||||||
| ARNC_ECOLI | P77757 | arnC pmrF yfbF | pmrF yfbF | b2254 JW2248 | integral IM protein (SEC in IM), Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase ArnC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 34 | 0.113 | CYT | 0 | -0.200913 | - | 2 | 2 | N | i238-259o271-295i | CytoplasmicMembrane | 10 | 13 | |||||
| HYFC_ECOLI | P77858 | hyfC | b2483 JW2468 | integral IM protein (SEC in IM), Hydrogenase-4 component C HyfC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 19 | 0.152 | CYT | 0 | -0.200913 | - | 8 | 8 | N | o12-32i77-99o105-127i139-161o173-195i231-249o255-278i290-311o | CytoplasmicMembrane | 10 | |||||||
| ATOS_ECOLI | Q06067 | atoS | b2219 JW2213 | integral IM protein (SEC in IM), Signal transduction histidine-kinase AtoS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.106 | TMH | 0 | 5.06915 | - | 2 | 2 | N | o16-35i192-210o | CytoplasmicMembrane | 10 | 27 | ||||||
| YAHH_ECOLI | Q2EEQ3 | yahH | b0322 JW5893 | integral IM protein (SEC in IM), Putative YahH | Membrane anchored by EchoLOCATION | Integral Inner Membrane | B | - | N/A | Membrane anchored | SEC | pseudogene (Uniprot), pseudogene (Ecogene) | no | no | N | 42 | 0.264 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||
| YNID_ECOLI | Q2EES1 | yniD | b4535 JW5911 | integral IM protein (SEC in IM), YniD | Integral Inner Membrane | Small membrane protein detected experimentally. | PMID: 19121005 | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Membrane | Membrane anchored | SRP | SEC | no | yes | N | 31 | 0.1 | TMH | 0 | 4.22082 | - | 1 | 0 | Y | n14-26c30/31o | CytoplasmicMembrane | 9 | ||||||
| YOHO_ECOLI | Q2EES6 | yohO | b4542 JW5354 | integral IM protein (SEC in IM), UPF0387 YohO | Integral Inner Membrane | Small membrane protein detected experimentally | PMID: 19121005 | Integral Inner Membrane | B | Binout | out/in | N/A | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 26 | 0.149 | TMH | 0 | 4.51604 | - | 1 | 1 | N | o6-31i | CytoplasmicMembrane | 9 | ||||||
| YPFN_ECOLI | Q2EET2 | ypfN | b4547 JW2457 | integral IM protein (SEC in IM), UPF0370 YpfN | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cell membrane | Membrane anchored | SRP | SEC | no | yes | N | 26 | 0.107 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o6-24i | Unknown | 2 | 71 | ||||||||
| YTJA_ECOLI | Q2M5U1 | ytjA | b4568 JW5891 | integral IM protein (SEC in IM), UPF0391 YtjA | Integral Inner Membrane | B | Binout | in/in | N/A | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.166 | TMH | 0 | 11.6664 | - | 2 | 1 | Y | n4-14c19/20o29-49i | CytoplasmicMembrane | 9 | |||||||||
| YOBH_ECOLI | Q2MB16 | yobH | b4536 JW5298 | integral IM protein (SEC in IM), YobH | Signal peptide predicted, single transmembrane helice predicted which would be removed upon signal peptide cleavage. Putative outer membrane or exported. Taxonomy: Klebsiella pneumoniae. | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | no | yes | N | 34 | 0.169 | TMH | 0 | 5.54741 | - | 1 | 0 | Y | n10-20c24/25o | CytoplasmicMembrane | 9 | 57 | ||||||||
| SIRB2_ECOLI | Q46755 | ychQ sirB2 | sirB2 | b1213 JW1204 | integral IM protein (SEC in IM), YchQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 39 | 0.138 | TMH | 0 | 6.48818 | - | 4 | 4 | N | o6-28i40-61o73-93i105-123o | CytoplasmicMembrane | 10 | 25 | |||||
| GHXQ_ECOLI | Q46817 | ghxQ ygfQ ygfR | ygfQ ygfR | b4464 JW5467 | integral IM protein (SEC in IM), Guanine/hypoxanthine permease GhxQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | yes | no | N | 65 | 0.11 | CYT | 0 | -0.200913 | - | 12 | 11 | N | i35-55o61-80i87-107o113-135i147-171o177-203i210-230o250-276i348-375o395-422i434-454o | CytoplasmicMembrane | 10 | |||||
| UACT_ECOLI | Q46821 | uacT ygfU | ygfU | b2888 JW5470 | integral IM protein (SEC in IM), Uric acid transporter UacT | Integral Inner Membrane | PMID: 15919996 PMID: 22437829 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.122 | CYT | 0 | -0.200913 | - | 12 | 12 | N | i30-52o64-86i93-112o118-138i145-167o179-198i205-225o255-278i332-354o360-381i393-413o419-442i | CytoplasmicMembrane | 10 | ||||||
| YGFX_ECOLI | Q46824 | ygfX cptA | cptA | b2896 JW2864 | integral IM protein (SEC in IM), YgfX | Integral Inner Membrane | PMID: 22239607 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | yes | yes | N | 39 | 0.141 | TMH | 0 | 5.61025 | - | 1 | 2 | N | i12-32o38-54i | CytoplasmicMembrane | 9 | 33 | |||||
| YQGA_ECOLI | Q46831 | yqgA | b2966 JW2934 | integral IM protein (SEC in IM), YqgA | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Cell membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 20 | 0.108 | TMH | 0 | 3.98827 | - | 6 | 8 | N | o6-23i30-50o56-75i103-123o135-157i164-181o187-206i213-233o | CytoplasmicMembrane | 10 | |||||||||
| YGHD_ECOLI | Q46832 | yghD ecfC | ecfC | b2968 JW2935 | integral IM protein (SEC in IM), Putative type II secretion system M-type YghD | Integral Inner Membrane | B | Bout | in/out | IM (predicted) | Cell inner membrane | Membrane anchored | SRP | SEC | no | yes | N | 43 | 0.102 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i38-57o | Unknown | 2 | 28 | |||||||
| YGHE_ECOLI | Q46833 | yghE | b2969 | integral IM protein (SEC in IM), Putative type II secretion system L-type YghE | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | pseudogene (Uniprot) | no | no | N | 38 | 0.296 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i136-159o | Unknown | 2 | ||||||||
| PPPA_ECOLI | Q46836 | pppA yghH | yghH | b2972 JW2939 | integral IM protein (SEC in IM), Leader peptidase PppA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | no | yes | N | 18 | 0.178 | TMH | 0 | 3.73276 | - | 7 | 7 | N | o12-33i102-119o125-142i149-167o179-199i211-241o247-265i | CytoplasmicMembrane | 10 | ||||||
| GLCA_ECOLI | Q46839 | glcA yghK | yghK | b2975 JW2942 | integral IM protein (SEC in IM), Glycolate permease GlcA | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein(experimental) | SRP | SEC | yes | yes | N | 34 | 0.266 | TMH | 0 | 14.6297 | - | 13 | 13 | N | i12-35o41-58i65-91o119-147i154-179o199-217i224-246o252-269i307-326o377-399i411-433o439-464i537-559o | CytoplasmicMembrane | 10 | ||||||
| YGHQ_ECOLI | Q46841 | yghQ | b2983 JW5490 | integral IM protein (SEC in IM), YghQ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | pseudogene (Ochman & Davalos, 2006) | no | yes | N | 53 | 0.148 | TMH | 0 | 1.31655 | - | 6 | 5 | N | o30-58i101-122o187-210i261-282o311-335i | CytoplasmicMembrane | 10 | ||||||
| YGHS_ECOLI | Q46843 | yghS | b2985 JW5491 | integral IM protein (SEC in IM), ATP-binding YghS | Integral Inner Membrane | B | Binout | in/out | IM (predicted) | Cytoplasmic | SRP | SEC | no | yes | N | 33 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i161-178o | Cytoplasmic | 8 | 35 | |||||||||
| YGHT_ECOLI | Q46844 | yghT | b2986 JW2954 | integral IM protein (SEC in IM), ATP-binding YghT | Integral Inner Membrane | B | Bin | out/in | IM (predicted) | Cytoplasmic | SRP | SEC | no | yes | N | 36 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o77-95i | Cytoplasmic | 8 | 50 | |||||||||
| YGIZ_ECOLI | Q46867 | ygiZ | b3027 JW2995 | integral IM protein (SEC in IM), YgiZ | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 31 | 0.138 | TMH | 0 | 4.05338 | - | 3 | 3 | N | i12-29o54-72i84-103o | CytoplasmicMembrane | 10 | 27 | ||||||
| LTND_ECOLI | Q46888 | ltnD ygbJ | ygbJ | b2736 JW2706 | integral IM protein (SEC in IM), L-threonate dehydrogenase LtnD | Belongs to the 3-hydroxyisobutyrate dehydrogenase family. | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane anchored | SRP | SEC | no | yes | N | 25 | 0.132 | SpI | 24 | 0.774969 | - | 1 | 0 | N | i | Cytoplasmic | 9 | 62 | |||||||
| YGBN_ECOLI | Q46892 | ygbN | b2740 JW2710 | integral IM protein (SEC in IM), permease YgbN | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein (Experimental) | SRP | SEC | yes | yes | N | 43 | 0.315 | TMH | 0 | 8.28022 | - | 11 | 11 | N | o6-22i29-47o53-75i102-133o175-197i237-261o273-294i306-331o351-380i392-409o429-453i | CytoplasmicMembrane | 10 | |||||||
| YGCS_ECOLI | Q46909 | ygcS | b2771 JW5845 | integral IM protein (SEC in IM), metabolite transport YgcS | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | no | yes | N | 37 | 0.129 | TMH | 0 | 7.45576 | - | 12 | 12 | N | i20-42o54-74i86-104o110-132i144-167o173-194i250-270o282-303i312-333o339-358i370-395o401-421i | CytoplasmicMembrane | 10 | |||||||
| GUDP_ECOLI | Q46916 | gudP ygcZ | ygcZ | b2789 JW2760 | integral IM protein (SEC in IM), Probable glucarate transporter GudP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 48 | 0.146 | TMH | 0 | 6.1738 | - | 12 | 12 | N | i17-34o54-75i87-105o111-129i150-173o179-198i255-280o292-316i328-347o353-374i386-408o414-435i | CytoplasmicMembrane | 10 | ||||||
| TCDA_ECOLI | Q46927 | tcdA csdL, ygdL | csdL, ygdL | b2812 JW2783 | integral IM protein (SEC in IM), tRNA threonylcarbamoyladenosine dehydratase TcdA | Integral Inner Membrane | PMID: 15174130 | Integral Inner Membrane | B | Bout | out/in | IM (predicted) | Membrane | Membrane anchored | SEC | yes | yes | N | 51 | 0.13 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o238-257i | Cytoplasmic | 9 | 68 | ||||||
| YQEI_ECOLI | Q46942 | yqeI | b2847 JW2815 | nucleoid & integral IM protein (SEC in IM), YqeI | Integral Inner Membrane, Nucleoid | PMID: 23138451 | Integral Inner Membrane, Nucleoid | B, N | IM (predicted) | Cytoplasmic | SRP | SEC | no | yes | N | 51 | 0.158 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i157-174o | Cytoplasmic | 8 | 15 | |||||||||
| YQEJ_ECOLI | Q46943 | yqeJ | b2848 JW5455 | integral IM protein (SEC in IM), YqeJ | Integral Inner Membrane | B | Bout | in/out | N/A | Membrane | Periplasmic | SRP | SEC | no | yes | N | 28 | 0.216 | SpI | 27 | 6.43067 | - | 1 | 1 | N | i7-27o | Unknown | 2 | |||||||||
| HCAT_ECOLI | Q47142 | hcaT yfhS | yfhS | b2536 JW2520 | integral IM protein (SEC in IM), Probable 3-phenylpropionic acid transporter HcaT | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | yes | yes | N | 20 | 0.106 | TMH | 0 | 10.8707 | - | 12 | 12 | N | i7-29o41-60i72-89o95-113i134-152o158-176i207-229o241-257i269-286o292-316i328-350o356-373i | CytoplasmicMembrane | 10 | ||||||||
| FADE_ECOLI | Q47146 | fadE yafH | yafH | b0221 JW5020 | integral IM protein (SEC in IM), Acyl-coenzyme A dehydrogenase FadE | Integral Inner Membrane | Trigger factor-sensitive aggregation. | PMID: 19737520 | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Integral Membrane Protein | SRP,TF | SEC | yes | yes | N | 46 | 0.138 | TMH | 0 | 11.7565 | - | 2 | 2 | Y | n3-13c17/18o27-58i279-296o | CytoplasmicMembrane | 9 | ||||||
| LFHA_ECOLI | Q47153 | lfhA fhiA | fhiA | b0229 JW5811 | integral IM protein (SEC in IM), Putative truncated export/assembly LfhA | Integral Inner Membrane | Outer membrane protein determined by 2D gel electrophoresis (Lopez-Campistrous et al 2005) | PMID: 15911532 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | pseudogene (Uniprot) | yes | no | N | 59 | 0.236 | CYT | 0 | -0.200913 | - | 3 | 3 | Y | n7-17c21/22o86-106i127-148o168-199i | CytoplasmicMembrane | 10 | 8 | |||
| ARNE_ECOLI | Q47377 | arnE pmrL yfbW | pmrL yfbW | b4544 JW2252 | integral IM protein (SEC in IM), Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/out | IM (predicted) | Cell inner membrane; Multi-pass membrane protein | Integral Membrane Protein | SRP | SEC | yes | yes | N | 16 | 0.131 | CYT | 0 | -0.200913 | - | 3 | 3 | Y | n4-15c21/22o37-58i65-85o91-110i | CytoplasmicMembrane | 10 | 77 | |||||
| YAIP_ECOLI | Q47536 | yaiP | b0363 JW0355 | integral IM protein (SEC in IM), glycosyltransferase YaiP | Integral Inner Membrane | B | Bpoly | out/out | IM (predicted) | Integral Membrane Protein | SRP | SEC | no | yes | N | 47 | 0.167 | CYT | 0 | -0.200913 | - | 4 | 3 | Y | n7-18c23/24o270-294i306-329o341-363i | CytoplasmicMembrane | 10 | 39 | |||||||||
| TAUC_ECOLI | Q47539 | tauC ssiC yaiJ | ssiC yaiJ | b0367 JW0359 | integral IM protein (SEC in IM), Taurine transport system permease TauC | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | no | yes | N | 43 | 0.113 | TMH | 0 | 4.41917 | - | 6 | 6 | N | i20-41o87-109i121-140o146-165i186-207o236-256i | CytoplasmicMembrane | 10 | 9 | |||||
| MMUP_ECOLI | Q47689 | mmuP ykfD | ykfD | b0260 JW5027 | integral IM protein (SEC in IM), Probable S-methylmethionine permease MmuP | Integral Inner Membrane | PMID: 15919996 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted) | Cell inner membrane | Integral Membrane Protein | SRP | SEC | Prophage Integrase (EcoGene) | yes | no | N | 34 | 0.108 | TMH | 0 | 11.5259 | - | 12 | 12 | N | i20-40o46-63i97-121o127-149i161-182o202-227i248-270o290-315i335-356o362-387i407-428o434-452i | CytoplasmicMembrane | 10 | |||||
| YQJK_ECOLI | Q47710 | yqjK | b3100 JW3071 | integral IM protein (SEC in IM), YqjK | Integral Inner Membrane | B | Binout | in/out | IM (predicted), Detected in IM Fraction | Membrane anchored | SRP | SEC | yes | yes | N | 62 | 0.14 | CYT | 0 | -0.200913 | - | 1 | 1 | N | i47-65o | Unknown | 2 | 30 | |||||||||
| COPA_ECOLI | Q59385 | copA atcU f834 ybaR | atcU f834 ybaR | b0484 JW0473 | integral IM protein (SEC-YidC in IM), Copper-exporting P-type ATPase CopA | Integral Inner Membrane | Exhibites aberrant localization by microscopy in the absence of YidC. PMID: 10639134 Disulfide bond-containing protein PMID: 25664544 | PMID: 10639134 PMID: 15919996 PMID: 22108384 PMID: 25664544 | Integral Inner Membrane | B | Bpoly | in/in | IM (predicted), Detected in IM Fraction | Copper-exporting P-type ATPase: Cell inner membrane | Integral Membrane Protein (Experimental) | SRP | SEC-YidC | no | yes | N | 50 | 0.162 | CYT | 0 | -0.200913 | - | 8 | 8 | N | i185-205o217-238i245-264o284-302i436-458o464-487i778-797o803-824i | CytoplasmicMembrane | 10 | 21 | ||||
| LDRD_ECOLI | Q6BF25 | ldrD | b4453 JW5966 | integral IM protein (SEC in IM), Small toxic polypeptide LdrD | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 21 | 0.155 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o14-31i | CytoplasmicMembrane | 9 | ||||||
| LDRB_ECOLI | Q6BF87 | ldrB | b4421 JW5958 | integral IM protein (SEC in IM), Small toxic polypeptide LdrB | Integral Inner Membrane | Potentially toxic protein. | PMID: 19121005 | Integral Inner Membrane | B | Binout | out/in | IM (predicted) | Cell inner membrane | Cytoplasmic | SRP | SEC | yes | yes | N | 21 | 0.121 | CYT | 0 | -0.200913 | - | 1 | 1 | N | o14-31i | CytoplasmicMembrane | 9 | ||||||
| YMGG_ECOLI | Q7DFV3 | ymgG | b1172 JW5178 | integral IM protein (SEC in IM), UPF0757 YmgG | Integral Inner Membrane | Belongs to the UPF0757 family. | PMID: 17787032 PMID: 18192383 | Integral Inner Membrane | B | Bpoly | in/in | N/A | Membrane anchored | SRP | SEC | no | yes | Y | 23 | 0.871 | SpI | 22 | 23.9513 | - | 2 | 0 | Y | n5-16c22/23o | Unknown | 2 | 98 |