| entry | acc | gene | alt_gene | oln | protein_name | cm_loca | cm_notes | cm_refs | suboci_full | subloci | subloci_iim | nterm_cterm | subloci_uniprot | subloci_echoL | bernsel | organelle | target_chaperoning1 | 1st_ss | target_chaperoning2 | 2nd_ss | pseudo | common_core | basic_proteome | signalp_sp_exist | signalp_pos | signalp_cmax | lipop_pred | lipop_cleavage | lipop_score | lipop_rule | tmhmm | phobius_tms | phobius_sp_exist | phobius_prediction | psortb_loca | psortb_score | solubility |
| CSGF_ECOLI | P0AE98 | csgF | b1038 JW1021 | Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Curli production assembly/transport component CsgF | Peripheral outer membrane protein facing the extra-cellular space (Experimental) Peripheral outer membrane protein facing the extra-cellular space (Probable) | Curli component. CsgF is secreted to the cell surface, where it mediates the cell-association and protease-resistance of the CsgB nucleator, suggesting that CsgF is required for specific localization and/or chaperoning of CsgB for full nucleator activity. Curli are a functional amyloid whose in vivo polymerization requires a dedicated nucleator protein, CsgB, and an assembly protein, CsgF. Without CsgF, curli subunits are released from the cell into the media and are inefficiently polymerized, resulting in fewer and mislocalized curli fibers. PMID: 19131513 PMID: 9928475 | PMID: 16522795 PMID: 19131513 PMID: 21645131 PMID: 9928475 | Peripheral outer membrane protein facing the extra-cellular space | F4 | F4 | Cell outer membrane | Periplasmic (Experimental) | N/A | Curli | SEC | Curli | yes | yes | Yes | 20 | 0.853 | SpI | 19 | 13.9164 | - | 1 | 0 | Y | n6-14c19/20o | Extracellular | 9 | 30 | |||||
| CSGA_ECOLI | P28307 | csgA | b1042 JW1025 | Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Major curlin subunit CsgA | Peripheral outer membrane protein facing the extra-cellular space (Experimental) Peripheral outer membrane protein facing the extra-cellular space (Probable) | Curli component. CsgA, is secreted from the cell in an unpolymerized form PMID: 11823641 The secretion and stability of CsgA and CsgB are dependent on the outer membrane lipoprotein CsgG. PMID: 21645131 Curli are a functional amyloid whose in vivo polymerization requires a dedicated nucleator protein, CsgB, and an assembly protein, CsgF. Without CsgF, curli subunits are released from the cell into the media and are inefficiently polymerized, resulting in fewer and mislocalized curli fibers. PMID: 19131513 PMID: 9383186 PMID: 9312041 During a process called interbacterial complementation, a csgB mutant cell secretes soluble CsgA that can be assembled on the surface of a cell expressing only csgB PMID: 8817489 High levels of both IbsC and ShoB lead to changes in membrane potential suggesting that both act at the membrane, consistent with the hydrophobic nature of the proteins. | PMID: 11823641 PMID: 18710431 PMID: 21645131 PMID: 8817489 PMID: 9312041 PMID: 9383186 | Peripheral outer membrane protein facing the extra-cellular space | F4 | F4 | Fimbrium | Cell surface appendage (Experimental) | N/A | Curli | SEC | Curli | yes | yes | Yes | 21 | 0.854 | SpI | 20 | 20.7833 | - | 0 | 0 | Y | n3-14c20/21o | Extracellular | 9 | 66 | |||||
| CSGB_ECOLI | P0ABK7 | csgB | b1041 JW1024 | Curli related extra-cellular peripheral OM protein (SEC through IM), secreted over OM by curli), Minor curlin subunit CsgB | Peripheral outer membrane protein facing the extra-cellular space (Experimental) Peripheral outer membrane protein facing the extra-cellular space (Probable) | Curli component. CsgB localization requires at least one component of the curli secretion apparatus, CsgF. Curli are a functional amyloid whose in vivo polymerization requires a dedicated nucleator protein, CsgB, and an assembly protein, CsgF. Without CsgF, curli subunits are released from the cell into the media and are inefficiently polymerized, resulting in fewer and mislocalized curli fibers. PMID: 19131513 PMID: 9383186 PMID: 9312041 | PMID: 19131513 PMID: 9312041 PMID: 9383186 | Peripheral outer membrane protein facing the extra-cellular space | F4 | F4 | Fimbrium | Cell surface appendage (Experimental) | N/A | Curli | SEC | Curli | yes | yes | Yes | 22 | 0.53 | SpI | 21 | 16.29 | - | 0 | 0 | Y | n5-13c21/22o | Extracellular | 9 | ||||||
| CSGG_ECOLI | P0AEA2 | csgG | b1037 JW1020 | Curli related OM lipoprotein & extra-cellular peripheral OM protein (SEC through IM), inserted in OM by LOL), Curli production assembly/transport component CsgG | Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space (Experimental) Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space (Probable) | Curli component. Proven signal peptidase II substrate. CsgG is an outer membrane protein required for the secretion of the two curli structural subunits CsgA and CsgB. CsgG is a lipoprotein that spans the outermembrane and assembles into an oligomeric annular-shaped structure with an inner diameter of approximately 2 nm (Margery L. Evans and Matthew R. Chapman in press). Overexpression of CsgG results in increased sensitivity to the small antibiotic erythromycin (740Da) but not the larger vancomycin (1440Da) suggesting that CsgG has a pore-like activity (Robinson et al 2006). PMID: 15174130 | PMID: 15174130 PMID: 21645131 | Outer Membrane Lipoprotein, Peripheral outer membrane protein facing the extra-cellular space | I, F4 | I,F4 | Cell membrane | Outer membrane Lipoprotein (Experimental) | N/A | Curli | SEC | LOL: Localization Of Lipoproteins | yes | yes | Yes | 20 | 0.544 | SpII | 15 | 12.9163 | Pos+2=L | 0 | 0 | Y | n4-13c18/19o | CytoplasmicMembrane | 9 | 44 | |||||
| CSGE_ECOLI | P0AE95 | csgE | b1039 JW1022 | Curli related periplasmic protein (SEC through IM), Curli production assembly/transport component CsgE | Periplasmic (Experimental) | Potential substrate of periplasmic peptidyl prolyl cis???trans isomerase SurA; sequence contains known binding motif of SurA [RYEF]X[RYEF][P]. Curli secretion specificity factor. CsgE provides substrate specificity to the curli secretion pore CsgG, and acts directly on the secretion substrate CsgA to prevent premature subunit assembly. PMID: 9928475 | PMID: 9928475 | Periplasmic | G | G | Periplasmic (Experimental) | N/A | Curli | SEC | SurA | yes | yes | Yes | 23 | 0.789 | SpI | 22 | 3.89784 | - | 0 | 0 | Y | n7-17c22/23o | Unknown | 2 | 15 | ||||||
| SECM_ECOLI | P62395 | secM srrA yacA | srrA yacA | b0097 JW5007 | cytoplasmic & periplasmic protein (SEC through IM), Secretion monitor SecM | Cytoplasmic, Periplasmic (Experimental) Cytoplasmic, Periplasmic (Probable) | SecM regulates secA expression by translational coupling of the secM secA operon. Fusion of SecM with alkaline phosphatase activity exhibits substantial activity in the periplasm. SecM periplasmic form is rapidly degraded. Potential substrate of periplasmic peptidyl prolyl cis???trans isomerase SurA; sequence contains known binding motif of SurA [RYEF]X[RYEF][P]. PMID: 11597451 | PMID: 11597451 PMID: 1834634 | Cytoplasmic, Periplasmic | A, G | A,G | Cytoplasm; cytosol | Periplasmic (Experimental) | N/A | SEC | SurA | yes | yes | Yes | 38 | 0.527 | SpI | 37 | 11.5151 | - | 1 | 0 | Y | n20-31c37/38o | Cytoplasmic | 10 | ||||||
| YGFZ_ECOLI | P0ADE8 | ygfZ yzzW | yzzW | b2898 JW2866 | cytoplasmic & periplasmic protein (SEC through IM), tRNA-modifying YgfZ | Cytoplasmic, Periplasmic (By similarity) Cytoplasmic, Periplasmic (Experimental) | Subcellular localization analysis of cytotoxic necrotizing factor 1 <a href="http://www.uniprot.org/uniprot/Q1R2U0">(CNF1)</a> demonstrated that YgfZ, a periplasmic protein, contributes to secretion of CNF1 (a normally cytoplasmic protein) into outer-membrane vesicles (OMVs) in pathogenic E.coli strain RS218 O18:K1:H7 PMID: 22174383. PMID: 9298646 | PMID: 22174383 PMID: 9298646 | Cytoplasmic, Periplasmic | A, G | A,G | Cytoplasm | Cytoplasmic (Experimental) | N/A | SEC | yes | yes | No | 31 | 0.252 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 82 | ||||||
| PMBA_ECOLI | P0AFK0 | pmbA tldE | tldE | b4235 JW4194 | cytoplasmic metalloprotease PmbA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 36 | 0.159 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 16 | ||||||||||
| TLDD_ECOLI | P0AGG8 | tldD yhdO | yhdO | b3244 JW3213 | cytoplasmic metalloprotease TldD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 13 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 90 | |||||||||||
| ARCA_ECOLI | P0A9Q1 | arcA cpxC dye fexA msp seg sfrA | cpxC dye fexA msp seg sfrA | b4401 JW4364 | cytoplasmic nucleoid peripheral IM protein, Aerobic respiration control ArcA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 18792681 PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 28 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 90 | ||||||||
| SYA_ECOLI | P00957 | alaS lovB | lovB | b2697 JW2667 | cytoplasmic nucleoid peripheral IM protein, Alanine--tRNA ligase AlaS | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | TF | no | yes | No | 26 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 57 | ||||||
| RHLB_ECOLI | P0A8J8 | rhlB mmrA | mmrA | b3780 JW3753 | cytoplasmic nucleoid peripheral IM protein, ATP-dependent RNA helicase RhlB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 18337249 PMID: 23230279 PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 56 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| PUTA_ECOLI | P09546 | putA poaA | poaA | b1014 JW0999 | cytoplasmic nucleoid peripheral IM protein, Bifunctional PutA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | The proline dehydrogenase PutA protein from S. typhimurium was shown to act as a membrane-associated enzyme or as a transcriptional repressor PMID: 8483946. Catabolism of proline requires PutA to associate with the membrane because reoxidation of the FAD cofactor in PutA needs the presence of an electron acceptor. Repression of the put operon requires PutA to bind to the put control-region DNA in the cytoplasm. Transcription factor PMID: 23138451. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23138451 PMID: 23230279 PMID: 8483946 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 64 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| CRP_ECOLI | P0ACJ8 | crp cap csm | cap csm | b3357 JW5702 | cytoplasmic nucleoid peripheral IM protein, cAMP-activated global transcriptional regulator Crp | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. | PMID: 15650111 PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 24 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| DNAA_ECOLI | P03004 | dnaA | b3702 JW3679 | cytoplasmic nucleoid peripheral IM protein, Chromosomal replication initiator DnaA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | C-terminal amphiphilic helix (355-370). Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10660626 PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 32 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 38 | ||||||||
| MUKB_ECOLI | P22523 | mukB | b0924 JW0907 | cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 11886550 PMID: 16982609 PMID: 20921377 PMID: 22380631 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 46 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||
| MUKE_ECOLI | P22524 | mukE kicA ycbA | kicA ycbA | b0923 JW0906 | cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukE | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 16982609 PMID: 20921377 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 25 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 85 | ||||||||
| MUKF_ECOLI | P60293 | mukF kicB | kicB | b0922 JW0905 | cytoplasmic nucleoid peripheral IM protein, Chromosome partition MukF | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 16982609 PMID: 20921377 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 37 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 76 | ||||||||
| CSGD_ECOLI | P52106 | csgD | b1040 JW1023 | cytoplasmic nucleoid peripheral IM protein, CsgBAC operon transcriptional regulatory protein CsgD | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. CsgD despite its function as a transcription activator, is localized in the cytoplasmic membrane. LuxR-type HTH domain signature and profile. The luxR-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 65 amino acids, present in transcription regulators of the LuxR/FixJ family of response regulators (PROSITE: PDOC0054). | PMID: 16513732 PMID: 20874755 PMID: 23138451 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 26 | 0.267 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 20 | ||||||||
| GYRA_ECOLI | P0AES4 | gyrA hisW nalA parD | hisW nalA parD | b2231 JW2225 | cytoplasmic nucleoid peripheral IM protein, DNA gyrase subunit A GyrA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 36 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 49 | ||||||
| GYRB_ECOLI | P0AES6 | gyrB acrB cou himB hisU nalC parA pcbA | acrB cou himB hisU nalC parA pcbA | b3699 JW5625 | cytoplasmic nucleoid peripheral IM protein, DNA gyrase subunit B GyrB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 54 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||
| DPO1_ECOLI | P00582 | polA resA | resA | b3863 JW3835 | cytoplasmic nucleoid peripheral IM protein, DNA polymerase I PolA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | no | yes | No | 59 | 0.268 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 76 | |||||||||
| DPS_ECOLI | P0ABT2 | dps pexB vtm | pexB vtm | b0812 JW0797 | cytoplasmic nucleoid peripheral IM protein, DNA protection during starvation Dps | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Nucleoid-associated protein (NAP) Dodecameric Dps forms a protein cage with a hollow interior that sequesters Fe 2+ and reduces hydroxyl radical formation PMID: 23701194 PMID: 7984106 | PMID: 21541338 PMID: 23230279 PMID: 7984106 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 53 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 44 | |||||||
| RADA_ECOLI | P24554 | radA sms | sms | b4389 JW4352 | cytoplasmic nucleoid peripheral IM protein, DNA repair RadA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 41 | 0.199 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 29 | |||||||||
| RECF_ECOLI | P0A7H0 | recF uvrF | uvrF | b3700 JW3677 | cytoplasmic nucleoid peripheral IM protein, DNA replication and repair RecF | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. The prokaryotic protein recF is a single-stranded DNA-binding protein which also probably binds ATP. RecF is involved in DNA metabolism; it is required for recombinational DNA repair and for induction of the SOS response. PMID: 1542576 | PMID: 1542576 PMID: 19766000 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 32 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | |||||||
| PARC_ECOLI | P0AFI2 | parC | b3019 JW2987 | cytoplasmic nucleoid peripheral IM protein, DNA topoisomerase 4 subunit A ParC | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Dimer of topoisomerase IV subunit A <a href="http://BioCyc.org/ECOLI/NEW-IMAGE?type=ENZYME&object=EG10686-MONOMER">(bioCyc)</a> Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1334483 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 18 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 17 | ||||||||
| FIS_ECOLI | P0A6R3 | fis | b3261 JW3229 | cytoplasmic nucleoid peripheral IM protein, DNA-binding Fis | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Nucleoid-associated protein (NAP). | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 19 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 110 | ||||||||
| HNS_ECOLI | P0ACF8 | hns bglY cur drdX hnsA msyA osmZ pilG topS | bglY cur drdX hnsA msyA osmZ pilG topS | b1237 JW1225 | cytoplasmic nucleoid peripheral IM protein, DNA-binding H-NS | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Experimentally verified gene-product. Methionine start codon is cleaved. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)PMID: 21541338. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 19 | 0.173 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 103 | |||||||
| DBHA_ECOLI | P0ACF0 | hupA | b4000 JW3964 | cytoplasmic nucleoid peripheral IM protein, DNA-binding HU-alpha HupA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)PMID: 21541338. Bacterial histone-like DNA-binding proteins signature (<a href="http://prosite.expasy.org/PDOC00044" targer="_blank">PDOC00044</a>). | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 24 | 0.244 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 96 | ||||||||
| DBHB_ECOLI | P0ACF4 | hupB hopD | hopD | b0440 JW0430 | cytoplasmic nucleoid peripheral IM protein, DNA-binding HU-beta HupB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)PMID: 21541338. Bacterial histone-like DNA-binding proteins signature | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 27 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| STPA_ECOLI | P0ACG1 | stpA hnsB | hnsB | b2669 JW2644 | cytoplasmic nucleoid peripheral IM protein, DNA-binding StpA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)PMID: 21541338. | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | yes | yes | No | 19 | 0.184 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||
| RPOA_ECOLI | P0A7Z4 | rpoA pez phs sez | pez phs sez | b3295 JW3257 | cytoplasmic nucleoid peripheral IM protein, DNA-directed RNA polymerase subunit alpha RpoA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 25 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| RPOB_ECOLI | P0A8V2 | rpoB groN nitB rif ron stl stv tabD | groN nitB rif ron stl stv tabD | b3987 JW3950 | cytoplasmic nucleoid peripheral IM protein, DNA-directed RNA polymerase subunit beta RpoB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 40 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| RPOC_ECOLI | P0A8T7 | rpoC tabB | tabB | b3988 JW3951 | cytoplasmic nucleoid peripheral IM protein, DNA-directed RNA polymerase subunit beta' RpoC | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 26 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| RPOZ_ECOLI | P0A800 | rpoZ | b3649 JW3624 | cytoplasmic nucleoid peripheral IM protein, DNA-directed RNA polymerase subunit omega RpoZ | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | The presence of omega subunit of RNA polymerase (RpoZ) is necessary for maturation of RNA polymerase. Experimentally verified gene-product. Methionine start codon is cleaved. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 35 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 81 | |||||||||
| HDA_ECOLI | P69931 | hda idaB yfgE | idaB yfgE | b2496 JW5397 | cytoplasmic nucleoid peripheral IM protein, DnaA regulatory inactivator Hda | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Homolgous to DnaA and more specific to C-terminal anchor of DnaA. | PMID: 12618445 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 33 | 0.157 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| RPOE_ECOLI | P0AGB6 | rpoE sigE | sigE | b2573 JW2557 | cytoplasmic nucleoid peripheral IM protein, ECF RNA polymerase sigma-E factor RpoE | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | SigmaE controls the ??E-dependent extracytoplasmic stress response and is required to maintain cell envelope integrity in Escherichia coli PMID: 9159523 PMID: 18253509. RseA, encodes an anti-sigma(E) activity demonstrated at both the genetic and biochemical levels PMID: 9159522. RseC is an inner membrane protein that positively modulates sigma(E) activity PMID: 9159522. ??E is held at the membrane by the antisigma factor RseA. Proteolysis of transmembrane and cytoplasmic portions of RseA by DegS frees the sigma(E) transcription factor. RseB binds to the periplasmic domain of RseA and protects RseA from proteolysis. PMID: 17360428. Unfolded OMPs activate the protease DegS, which cleave RpoE regulon PMID: 15520285. Identified in the inner membrane by biochemical followed by two-dimensional gel electrophoresis and tandem mass spectrometry PMID: 15911532. PMID: 15774872 PMID: 16597971 PMID: 11777003 Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA reveals that RseA functions by sterically occluding the two primary binding determinants on sigma(E) for core RNA polymerase. PMID: 12718891 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11777003 PMID: 15520285 PMID: 15774872 PMID: 15911532 PMID: 16597971 PMID: 17360428 PMID: 20971899 PMID: 23138451 PMID: 23230279 PMID: 7889934 PMID: 9159522 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 44 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 101 | |||||||
| RNB_ECOLI | P30850 | rnb | b1286 JW1279 | cytoplasmic nucleoid peripheral IM protein, Exoribonuclease 2 Rnb | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Membrane association via an amino-terminal amphipathic helix is required for the cellular organization and function of RNase II PMID: 23344958 Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 23344958 PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 23 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 48 | ||||||||
| CYSB_ECOLI | P0A9F3 | cysB | b1275 JW1267 | cytoplasmic nucleoid peripheral IM protein, HTH-type transcriptional regulator CysB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 24 | 0.141 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 8 | |||||||||
| MALT_ECOLI | P06993 | malT malA | malA | b3418 JW3381 | cytoplasmic nucleoid peripheral IM protein, HTH-type transcriptional regulator MalT | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Cytoplasmic transciption factor that binds maltotriose and ATP and shuttles between the chromosome and membranes as a peripheral protein on the MalK peripheral ATPase of the maltose transporter. Trigger factor-sensitive aggregation. LuxR-type HTH domain signature and profile. The luxR-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 65 amino acids, present in transcription regulators of the LuxR/FixJ family of response regulators (PROSITE: PDOC0054). | PMID: 15063852 PMID: 23138451 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 36 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 7 | 8 | |||||||
| MLRA_ECOLI | P33358 | mlrA yehV | yehV | b2127 JW2115 | cytoplasmic nucleoid peripheral IM protein, HTH-type transcriptional regulator MlrA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | MlrA has regulatory role in transcription activation of csgD, which is the master regulator of biofilm formation. | PMID: 20874755 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 23 | 0.15 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o135-155i | Cytoplasmic | 9 | 114 | ||||||||
| IHFA_ECOLI | P0A6X7 | ihfA hid himA | hid himA | b1712 JW1702 | cytoplasmic nucleoid peripheral IM protein, Integration host factor subunit alpha IhfA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Translation. Experimentally verified gene-product. Methionine start codon is cleaved. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)PMID: 21541338. Bacterial histone-like DNA-binding proteins signature | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm; nucleoid | Cytoplasmic | N/A | no | yes | No | 24 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| IHFB_ECOLI | P0A6Y1 | ihfB himD hip | himD hip | b0912 JW0895 | cytoplasmic nucleoid peripheral IM protein, Integration host factor subunit beta IhfB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Translation, nucleoid-associated protein (NAP). Bacterial histone-like DNA-binding proteins signature | PMID: 21541338 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 39 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 23 | |||||||
| LRP_ECOLI | P0ACJ0 | lrp alsB ihb livR oppI | alsB ihb livR oppI | b0889 JW0872 | cytoplasmic nucleoid peripheral IM protein, Leucine-responsive regulatory protein Lrp | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 48 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 36 | |||||||||
| MATP_ECOLI | P0A8N0 | matP ycbG | ycbG | b0956 JW0939 | cytoplasmic nucleoid peripheral IM protein, Macrodomain Ter protein MatP | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 18984159 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | N/A | yes | yes | No | 37 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 92 | ||||||||
| MLC_ECOLI | P50456 | mlc | b1594 JW1586 | cytoplasmic nucleoid peripheral IM protein, Mlc | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Cytoplasmic global repressor of gene transcription that is recruited to the inner membrane where it binds the PtsB protein after the latter has been phosphorylated. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15255904 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 43 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | |||||||||
| YBBO_ECOLI | P0AFP4 | ybbO | b0493 JW0482 | cytoplasmic nucleoid peripheral IM protein, Oxidoreductase YbbO | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 45 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o240-258i | Cytoplasmic | 9 | |||||||||||
| PHOB_ECOLI | P0AFJ5 | phoB | b0399 JW0389 | cytoplasmic nucleoid peripheral IM protein, Phosphate regulon transcriptional regulatory PhoB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PhoB is a dual transcription regulator that activates expression of the Pho regulon in response to environmental Pi. Under phosphate limitation conditions the inner membrane sensor kinase PhoR autophosphorylates; Subsequent transfer of the phosphate group to PhoB results in activation of PhoB. It has been shown that PhoBR and PhoB are responsible for upregulation of phosphonate and glycerol phosphate metabolism and the high-affinity phosphate transport system, respectively, thus showing the complex regulation by the PhoR-PhoB two-component regulatory system. | PMID: 18031348 PMID: 23138451 PMID: 2693738 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.201 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| FECI_ECOLI | P23484 | fecI | b4293 JW4253 | cytoplasmic nucleoid peripheral IM protein, Probable RNA polymerase sigma factor FecI | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Interacts with FecR at the inner membrane propably through the N-terminal region of FecR (1-85) which is cytoplasmicPMID: 16718597. FecR spans the cytoplasmic membrane once, interacts in the periplasm with its C-terminal region with FecA occupied by ferric citrate, and transmits the information through the cytoplasmic membrane into the cytoplasm, where it converts FecI into an active sigma factorPMID: 9573190. FecI specifically binds FecR (a transmembrane protein) and that this binding is necessary for FecI to function as a sigma factorPMID: 12057967. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12057967 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | no | yes | No | 23 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 16 | |||||||||
| RRAA_ECOLI | P0A8R0 | rraA menG yiiV | menG yiiV | b3929 JW3900 | cytoplasmic nucleoid peripheral IM protein, Regulator of ribonuclease activity A RraA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Negative regulator of RNaseE. Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 34 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| RRAB_ECOLI | P0AF90 | rraB yjgD | yjgD | b4255 JW4212 | cytoplasmic nucleoid peripheral IM protein, Regulator of ribonuclease activity B RraB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Negative regulator of RNaseE. Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 41 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||
| DNAB_ECOLI | P0ACB0 | dnaB groP grpA | groP grpA | b4052 JW4012 | cytoplasmic nucleoid peripheral IM protein, Replicative DNA helicase DnaB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 3 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | |||||||
| RNC_ECOLI | P0A7Y0 | rnc | b2567 JW2551 | cytoplasmic nucleoid peripheral IM protein, Ribonuclease 3 Rnc | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | Copurifies with trigger factor in pull down assays. Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 24438330 PMID: 4865702 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 56 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 116 | |||||||
| RPOD_ECOLI | P00579 | rpoD alt | alt | b3067 JW3039 | cytoplasmic nucleoid peripheral IM protein, RNA polymerase sigma factor RpoD | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 26 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | ||||||
| RPOS_ECOLI | P13445 | rpoS appR katF nur otsX sigS | appR katF nur otsX sigS | b2741 JW5437 | cytoplasmic nucleoid peripheral IM protein, RNA polymerase sigma factor RpoS | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 69 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 30 | ||||||||
| RPPH_ECOLI | P0A776 | rppH nudH ygdP | nudH ygdP | b2830 JW2798 | cytoplasmic nucleoid peripheral IM protein, RNA pyrophosphohydrolase RppH | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 25 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | ||||||||
| HFQ_ECOLI | P0A6X3 | hfq | b4172 JW4130 | cytoplasmic nucleoid peripheral IM protein, RNA-binding Hfq | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Nucleoid (Experimental) | The Escherichia coli hflA locus encodes a putative GTP-binding protein and two membrane proteins, one of which contains a protease-like domain. Is a bacterial protein involved in several aspects of nucleic acid transactions. Nucleoid-associated protein (NAP) that binds sequence-nonspecific DNA. Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 20011543 PMID: 21541338 PMID: 24438330 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | yes | yes | No | 53 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 75 | |||||||||
| NUSA_ECOLI | P0AFF6 | nusA | b3169 JW3138 | cytoplasmic nucleoid peripheral IM protein, Transcription termination/antitermination NusA | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Fluorescent fusions of NusA have been monitored via fluorescence microscopy. NusA was found to be located predominantly in two clusters associated with each nucleoid. NusA can self-assemble into oligomers under heat shock conditions. NusA also acquires chaperone activity. | PMID: 17272300 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 41 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 99 | ||||||||
| CPXR_ECOLI | P0AE88 | cpxR yiiA | yiiA | b3912 JW3883 | cytoplasmic nucleoid peripheral IM protein, transcriptional regulator CpxR | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23138451 PMID: 23230279 PMID: 8294007 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 32 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 118 | ||||||||
| OMPR_ECOLI | P0AA16 | ompR kmt ompB | kmt ompB | b3405 JW3368 | cytoplasmic nucleoid peripheral IM protein, transcriptional regulator OmpR | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 38 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 87 | ||||||||
| RCSB_ECOLI | P0DMC7 | rcsB | b2217 JW2205 | cytoplasmic nucleoid peripheral IM protein, transcriptional regulator RcsB | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Potential) | Regulator protein RcsB is a member of the two-component regulatory system RcsC/RcsB. It is involved in the activation of colanic acid capsule synthesis (cps) and cell division (ftsZ) genes. It is believed that the RcsB protein is activated through phosphorylation, probably by the sensor protein RcsC. RcsB protein for Regulator capsule synthesis B, is a response regulator that belongs to the multicomponent RcsF/RcsC/RcsD/RcsA-RcsB phosphorelay system. LuxR-type HTH domain signature and profile. The luxR-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 65 amino acids, present in transcription regulators of the LuxR/FixJ family of response regulators (PROSITE: PDOC0054). | PMID: 2404948 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cytoplasmic | N/A | no | yes | No | 66 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 90 | |||||||||
| NADR_ECOLI | P27278 | nadR nadI | nadI | b4390 JW5800 | cytoplasmic nucleoid peripheral IM protein, Trifunctional NAD biosynthesis/regulator NadR | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm (Probable) | May loosely associate with the membrane through its interaction with the membrane-bound pnuC (Nicotinamide riboside transporter). In combination with corepressor (NAD?), the cytoplasmic form of nadR would be capable of acting as a transcriptional repressor. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10464228 PMID: 23138451 PMID: 23230279 | Cytoplasmic, Nucleoid, Peripheral inner membrane protein facing the cytoplasm | A, N, F1 | A,N,F1 | Cell membrane; Peripheral membrane protein Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 39 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 39 | |||||||
| AMPH_ECOLI | P0AD70 | ampH yaiH | yaiH | b0376 JW5052 | cytoplasmic peripheral IM protein (SEC through IM), D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Potential substrate of periplasmic peptidyl prolyl cis???trans isomerase SurA. Sequence contains known binding motif of SurA [RYEF]X[RYEF][P]. The N-terminal export signal of AmpH is processed, but the protein remains membrane associated. Disulfide bond-containing protein PMID: 25664544 | PMID: 22001512 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Periplasmic | N/A | SurA | yes | yes | Yes | 22 | 0.613 | SpI | 21 | 16.801 | - | 0 | 0 | Y | n5-16c21/22o | Periplasmic | 9 | 41 | ||||||
| AEEP_ECOLI | P51981 | ycjG ycjH | ycjH | b1325 JW1318 | cytoplasmic peripheral IM protein (SEC through IM), L-Ala-D/L-Glu epimerase YcjG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 21 | 0.226 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 19 | |||||||||
| ENO_ECOLI | P0A6P9 | eno | b2779 JW2750 | cytoplasmic peripheral IM protein facing the cytoplasm & peripheral OM protein facing the extra-cellular space (SEC through IM), Enolase Eno | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space (Probable) | When modified at Lys342 possibly secreted by an unknown mechanism, no evidence of signal peptide) Homodimer, stabilized by Mg2+; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. Essential for the degradation of carbohydrates via glycolysis. Also a component of the RNA degradosome. The covalent binding to the substrate at Lys-342 causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. Interacts with the C-terminal region of the endoribonuclease RNase EIn the RNA degradosome. Fractions of enolase are present in both the cytoplasm and on the cell surface. As part of the bacterial cytoskeleton in the cytoplasm,Is organized as extended coiled structures that wind around the cell, from one cell pole to the other. When covalently bound to the substrate at Lys-342, the inactive enolase is secreted, and remains attached to the bacterial cell surface. PMID: 8610017 PMID: 9600841 PMID: 9740056 PMID: 9732527 PMID: 12035760 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12035760 PMID: 15003462 PMID: 17242352 PMID: 18337249 PMID: 23230279 PMID: 8610017 PMID: 9600841 PMID: 9732527 PMID: 9740056 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, Peripheral outer membrane protein facing the extra-cellular space | A, F1, F4 | A,F1,F4 | Cytoplasm; cytoskeleton Secreted Cell surface | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | SEC | yes | yes | No | 42 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 100 | |||||||
| DNAK_ECOLI | P0A6Y8 | dnaK groP grpF seg | groP grpF seg | b0014 JW0013 | cytoplasmic peripheral IM protein of Hsp70 family, Chaperone DnaK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | DnaK associates with the inner membrane. The ability to isolate DnaK with a membrane fraction prepared under gentle lysis conditions supports a peripheral association between DnaK and the cytoplasmic membrane. PMID: 7961473 Overexpression of three different membrane proteins (YidC, YedZ, and LepI) fused to green fluorescent protein (GFP) led to an increased association (2.3???4.8-fold) of DnaK with the membrane. PMID: 17446557 PMID: 1396676 PMID: 7783627 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Interacts with DmsD is a redox enzyme maturation protein (REMP). PMID: 20153451 | PMID: 1396676 PMID: 16079137 PMID: 17446557 PMID: 20153451 PMID: 23230279 PMID: 7783627 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 115 | |||||||
| LOLD_ECOLI | P75957 | lolD ycfV | ycfV | b1117 JW5162 | cytoplasmic peripheral IM protein, -releasing system ATP-binding LolD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 65 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 25 | ||||||||
| PAAC_ECOLI | P76079 | paaC ydbP | ydbP | b1390 JW1385 | cytoplasmic peripheral IM protein, 1,2-phenylacetyl-CoA epoxidase, subunit C PaaC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 57 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||
| DXS_ECOLI | P77488 | dxs yajP | yajP | b0420 JW0410 | cytoplasmic peripheral IM protein, 1-deoxy-D-xylulose-5-phosphate synthase Dxs | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | YeaA has been viewed through fluorescence microscopy and located evenly throughout cytoplasm. Small scale study of labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. PMID: 17272300 | PMID: 17272300 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 52 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 21 | ||||||||
| CH10_ECOLI | P0A6F9 | groS groES mopB | groES mopB | b4142 JW4102 | cytoplasmic peripheral IM protein, 10 kDa chaperonin GroS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 20153451 PMID: 22380631 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 43 | 0.185 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 86 | ||||||||
| DAPD_ECOLI | P0A9D8 | dapD | b0166 JW0161 | cytoplasmic peripheral IM protein, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 24 | 0.195 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 41 | |||||||||
| GPMA_ECOLI | P62707 | gpmA gpm pgm pgmA | gpm pgm pgmA | b0755 JW0738 | cytoplasmic peripheral IM protein, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase GpmA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 41 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 102 | |||||||||
| KBL_ECOLI | P0AB77 | kbl | b3617 JW3592 | cytoplasmic peripheral IM protein, 2-amino-3-ketobutyrate coenzyme A ligase Kbl | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 34 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 37 | ||||||||
| RIDA_ECOLI | P0AF93 | ridA yjgF | yjgF | b4243 JW5755 | cytoplasmic peripheral IM protein, 2-iminobutanoate/2-iminopropanoate deaminase RidA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Experimentally verified gene-product. Methionine start codon is cleaved. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 21 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 75 | |||||||
| UBIH_ECOLI | P25534 | ubiH visB | visB | b2907 JW2875 | cytoplasmic peripheral IM protein, 2-octaprenyl-6-methoxyphenol hydroxylase UbiH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | The biosynthesis of UQ is studied in great detail in bacteria and yeast but only to a limited extent in animal tissues. The UQ biosynthetic enzymes may constitute a complex that is tightly bound to the membrane. | PMID: 11583838 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 42 | 0.38 | SpI | 25 | 1.25365 | - | 0 | 0 | Y | n3-13c18/19o | Unknown | 6 | 15 | ||||||||
| ODO1_ECOLI | P0AFG3 | sucA | b0726 JW0715 | cytoplasmic peripheral IM protein, 2-oxoglutarate dehydrogenase E1 component SucA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 24 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | ||||||||
| MENE_ECOLI | P37353 | menE | b2260 JW2255 | cytoplasmic peripheral IM protein, 2-succinylbenzoate--CoA ligase MenE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homologous to FadD13 protein of Mycobacterium that is peripheral. | PMID: 22560731 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 48 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | |||||||||
| RLUF_ECOLI | P32684 | rluF yjbC | yjbC | b4022 JW3982 | cytoplasmic peripheral IM protein, 23S rRNA pseudouridine(2604) synthase RluF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 25 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| CYSQ_ECOLI | P22255 | cysQ amtA | amtA | b4214 JW4172 | cytoplasmic peripheral IM protein, 3'(2'),5'-bisphosphate nucleotidase CysQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 15911532 | PMID: 15911532 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Membrane associated (Experimental) | N/A | no | yes | No | 40 | 0.152 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 83 | |||||||
| RIBB_ECOLI | P0A7J0 | ribB htrP | htrP | b3041 JW3009 | cytoplasmic peripheral IM protein, 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | yes | yes | No | 22 | 0.191 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 116 | ||||||||||
| KDSC_ECOLI | P0ABZ4 | kdsC yrbI yrbJ | yrbI yrbJ | b3198 JW3165 | cytoplasmic peripheral IM protein, 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Short signal peptide of 17aa. Prediction by Phobius and the SignalP NN approach/extensive islands of hydrophobicity by K/D. No obvious biochemical reason that the enzyme should be secreted. Signal peptide like sequence could act as peripheral membrane association element. Lipopolysaccharide (LPS) is an amphiphilic molecule composed of a hydrophilic heteropolysaccharide and the membrane-embedded Lipid A. The innermost 8-carbon sugar 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) is the only conserved structural element found in all LPS, linking the lipid A to the carbohydrate domain of the molecule. The KDO 8-phosphate phosphatase (KdsC) is one of the enzymes of the KDO biosynthesis pathway and is responsible for cleavage of the phosphate group from KDO 8-phosphate to yield KDO. PMID: 12639950 In Escherichia coli, KdsC has been characterized as a homotetrameric molecule with a random-coiled C-terminal tail in each subunit. PMID: 12639950 PMID: 12639950 | PMID: 12639950 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | yes | yes | No | 18 | 0.326 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-12c17/18o | Cytoplasmic | 9 | 90 | ||||||||
| FABZ_ECOLI | P0A6Q6 | fabZ sefA yaeA | sefA yaeA | b0180 JW0175 | cytoplasmic peripheral IM protein, 3-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. PMID: 8354462 PMID: 7806516 PMID: 8805534 PMID: 8910376 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15911532 PMID: 23230279 PMID: 7806516 PMID: 8354462 PMID: 8805534 PMID: 8910376 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | TF | yes | yes | No | 32 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 27 | ||||||
| FADI_ECOLI | P76503 | fadI yfcY | yfcY | b2342 JW2339 | cytoplasmic peripheral IM protein, 3-ketoacyl-CoA thiolase FadI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 32 | 0.192 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | ||||||||
| UBID_ECOLI | P0AAB4 | ubiD yigC yigY | yigC yigY | b3843 JW3819 | cytoplasmic peripheral IM protein, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | IM (predicted) | yes | yes | No | 65 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 37 | |||||||
| FABG_ECOLI | P0AEK2 | fabG | b1093 JW1079 | cytoplasmic peripheral IM protein, 3-oxoacyl-(acyl-carrier-protein) reductase FabG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 23 | 0.249 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 93 | ||||||||||
| FABB_ECOLI | P0A953 | fabB fabC | fabC | b2323 JW2320 | cytoplasmic peripheral IM protein, 3-oxoacyl-(acyl-carrier-protein) synthase 1 FabB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 25 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-15c24/25o | Cytoplasmic | 10 | 13 | ||||||||
| FABF_ECOLI | P0AAI5 | fabF fabJ | fabJ | b1095 JW1081 | cytoplasmic peripheral IM protein, 3-oxoacyl-(acyl-carrier-protein) synthase 2 FabF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 48 | 0.158 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n6-14c20/21o | Cytoplasmic | 9 | 8 | |||||||||
| HSLO_ECOLI | P0A6Y5 | hslO yrfI | yrfI | b3401 JW5692 | cytoplasmic peripheral IM protein, 33 kDa chaperonin HslO | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bridge (230 232;263 266) PMID: 10764757 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 63 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 88 | |||||||
| MALQ_ECOLI | P15977 | malQ malA | malA | b3416 JW3379 | cytoplasmic peripheral IM protein, 4-alpha-glucanotransferase MalQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 23 | 0.214 | SpI | 22 | 0.437923 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 31 | |||||||
| GABT_ECOLI | P22256 | gabT | b2662 JW2637 | cytoplasmic peripheral IM protein, 4-aminobutyrate aminotransferase GabT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 65 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 77 | ||||||||||
| ISPG_ECOLI | P62620 | ispG gcpE | gcpE | b2515 JW2499 | cytoplasmic peripheral IM protein, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 44 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| RISB_ECOLI | P61714 | ribE ribH ybaF | ribH ybaF | b0415 JW0405 | cytoplasmic peripheral IM protein, 6,7-dimethyl-8-ribityllumazine synthase RibE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 69 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| 6PGD_ECOLI | P00350 | gnd | b2029 JW2011 | cytoplasmic peripheral IM protein, 6-phosphogluconate dehydrogenase, decarboxylating Gnd | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 20 | 0.182 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 90 | ||||||||||
| CH60_ECOLI | P0A6F5 | groL groEL mopA | groEL mopA | b4143 JW4103 | cytoplasmic peripheral IM protein, 60 kDa chaperonin GroL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 58 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 94 | |||||||
| MODF_ECOLI | P31060 | modF phrA | phrA | b0760 JW0743 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding ModF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | no | yes | No | 34 | 0.221 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 33 | ||||||||||
| UUP_ECOLI | P43672 | uup ycbH ycbI | ycbH ycbI | b0949 JW0932 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding Uup | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||
| YADG_ECOLI | P36879 | yadG | b0127 JW0123 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YadG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Homolog to import ATP-binding protein MalK. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 31 | 0.246 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 5 | |||||||||
| YBBA_ECOLI | P0A9T8 | ybbA | b0495 JW0484 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YbbA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 41 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 102 | ||||||||||
| YBIT_ECOLI | P0A9U3 | ybiT | b0820 JW0804 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YbiT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homolog to import ATP-binding protein MalK. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 19 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 42 | |||||||||
| YDCT_ECOLI | P77795 | ydcT | b1441 JW1436 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YdcT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 20 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 26 | ||||||||||
| YEJF_ECOLI | P33916 | yejF | b2180 JW2168 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YejF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 35 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | |||||||||||
| YHES_ECOLI | P63389 | yheS | b3352 JW3315 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YheS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Phospholipid ABC transporter-binding protein ATP-binding proteins phospholipid ABC transporter-binding protein ATP-binding proteins Trigger factor-sensitive aggregation. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 54 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 39 | |||||||||
| YNJD_ECOLI | P76909 | ynjD | b1756 JW5286 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YnjD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 53 | 0.159 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 19 | ||||||||||
| YPHE_ECOLI | P77509 | yphE | b2547 JW2531 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YphE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 26 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 5 | ||||||||||
| YTFR_ECOLI | Q6BEX0 | ytfR ytfS | ytfS | b4485 JW5752 | cytoplasmic peripheral IM protein, ABC transporter ATP-binding YtfR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | pseudogene (Ochman & Davalos, 2006) | no | yes | No | 25 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 24 | ||||||||
| ACKA_ECOLI | P0A6A3 | ackA ack | ack | b2296 JW2293 | cytoplasmic peripheral IM protein, Acetate kinase AckA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 20 | 0.328 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 112 | ||||||||
| ACCA_ECOLI | P0ABD5 | accA | b0185 JW0180 | cytoplasmic peripheral IM protein, Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha AccA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 28 | |||||||||
| ACCD_ECOLI | P0A9Q5 | accD dedB usg | dedB usg | b2316 JW2313 | cytoplasmic peripheral IM protein, Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta AccD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation related. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 18 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | |||||||
| ACSA_ECOLI | P27550 | acs yfaC | yfaC | b4069 JW4030 | cytoplasmic peripheral IM protein, Acetyl-coenzyme A synthetase Acs | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homologous to FadD13 protein of Mycobacterium that is peripheral. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 22560731 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 27 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | ||||||||
| ARGB_ECOLI | P0A6C8 | argB | b3959 JW5553 | cytoplasmic peripheral IM protein, Acetylglutamate kinase ArgB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | |||||||||
| ARGE_ECOLI | P23908 | argE | b3957 JW3929 | cytoplasmic peripheral IM protein, Acetylornithine deacetylase ArgE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 23 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 42 | |||||||||
| ACNB_ECOLI | P36683 | acnB yacI yacJ | yacI yacJ | b0118 JW0114 | cytoplasmic peripheral IM protein, Aconitate hydratase B AcnB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. PMID: 10585860 Disulfide bond-containing protein PMID: 25664544 | PMID: 10585860 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | TF | yes | yes | No | 42 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 90 | |||||||
| ACP_ECOLI | P0A6A8 | acpP | b1094 JW1080 | cytoplasmic peripheral IM protein, Acyl carrier AcpP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Part of phospholipid metabolism complex PlsB-PssA-YbgC-AcpPMID: 16294310. Various methods were used to demonstrate that ACP could be cross-linked specifically to an inner membrane protein of E. coli, most probably to the glycerol-3-phosphate acyl transferase (GPAT)PMID: 1310877. Evidence for interactions of acyl carrier protein with glycerol-3-phosphate acyltransferase, an inner membrane protein of Escherichia coliPMID: 2676605. Membrane vesicles of Escherichia coli contain protein-binding sites for acyl carrier proteinPMID: 2668033. PMID: 3884600 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1310877 PMID: 23230279 PMID: 2668033 PMID: 2676605 PMID: 3884600 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | pseudogene (Ochman & Davalos, 2006) | no | yes | No | 47 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||
| YBGC_ECOLI | P0A8Z3 | ybgC | b0736 JW0726 | cytoplasmic peripheral IM protein, Acyl-CoA thioester hydrolase YbgC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Phospholipid metabolism complex PlsB-PssA-YbgC-acp | PMID: 16294310 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 52 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 70 | ||||||||
| ADD_ECOLI | P22333 | add | b1623 JW1615 | cytoplasmic peripheral IM protein, Adenosine deaminase Add | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 40 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | ||||||||||
| KAD_ECOLI | P69441 | adk dnaW plsA | dnaW plsA | b0474 JW0463 | cytoplasmic peripheral IM protein, Adenylate kinase Adk | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Adk cell localization has been monitored via fluorescence microscopy after protein was chromosomally tagged with fluorescent protein/s. These experiments indicate that Adk is distributed diffusely throughout cytoplasm. PMID: 8650159 | PMID: 17272300 PMID: 23230279 PMID: 8650159 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 18 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-12c17/18o | Cytoplasmic | 10 | 104 | |||||||
| PUR8_ECOLI | P0AB89 | purB | b1131 JW1117 | cytoplasmic peripheral IM protein, Adenylosuccinate lyase PurB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 61 | 0.215 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 74 | ||||||||||
| PURA_ECOLI | P0A7D4 | purA adeK | adeK | b4177 JW4135 | cytoplasmic peripheral IM protein, Adenylosuccinate synthetase PurA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 62 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 41 | ||||||||
| RFAF_ECOLI | P37692 | rfaF waaF | waaF | b3620 JW3595 | cytoplasmic peripheral IM protein, ADP-heptose--LPS heptosyltransferase 2 RfaF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 42 | 0.134 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 24 | |||||||||
| HLDD_ECOLI | P67910 | hldD htrM rfaD waaD | htrM rfaD waaD | b3619 JW3594 | cytoplasmic peripheral IM protein, ADP-L-glycero-D-manno-heptose-6-epimerase HldD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 2198271 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | yes | yes | No | 19 | 0.195 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 26 | |||||||||
| ADPP_ECOLI | Q93K97 | nudF aspP yqiE yzzG | aspP yqiE yzzG | b3034 JW3002 | cytoplasmic peripheral IM protein, ADP-ribose pyrophosphatase NudF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble IM Fraction + | yes | yes | No | 38 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 57 | |||||||||
| GLPD_ECOLI | P13035 | glpD glyD | glyD | b3426 JW3389 | cytoplasmic peripheral IM protein, Aerobic glycerol-3-phosphate dehydrogenase GlpD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Binds to the cytoplasmic membrane through an amphipathic C-terminal alpha-helix (357-374)PMID: 11955283. Identified in PlsB-PflB-GlpD-Psd PMID: 20521846. Detergent-depleted enzyme can be functionally reconstituted with Escherichia coli membrane vesicles to support glycerol-3-phosphate-dependent active transport of L-prolinePMID: 340460. When GlpD is lost by mutation, the cells not only fail to grow on glycerol or l-alpha-glycerophosphate, but are subject to growth inhibition in the presence of either compound PMID: 5321485. Glycerol-P dehydrogenase is a primary dehydrogenase in the electron transport chain. It functions in vitro only when associated with the cytoplasmic membrane. The enzyme has been purified from the membrane fraction after solubilization with deoxycholate. PMID: 1987111 GlpD enzyme is membrane bound. The active site has been located at the cytoplasmic (inner) face of the membrane. PMID: 6387427 Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 8982270 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11955283 PMID: 15911532 PMID: 15919657 PMID: 23230279 PMID: 340460 PMID: 8982270 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 35 | 0.138 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 48 | |||||||
| ALR2_ECOLI | P29012 | dadX alnB dadB | alnB dadB | b1190 JW1179 | cytoplasmic peripheral IM protein, Alanine racemase, catabolic DadX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 25 | 0.206 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 2 | |||||||||
| YQHD_ECOLI | Q46856 | yqhD | b3011 JW2978 | cytoplasmic peripheral IM protein, Alcohol dehydrogenase YqhD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 21 | 0.138 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 91 | ||||||||||
| ADHP_ECOLI | P39451 | adhP yddN | yddN | b1478 JW1474 | cytoplasmic peripheral IM protein, Alcohol dehydrogenase, propanol-preferring AdhP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 40 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 86 | |||||||||
| YAHK_ECOLI | P75691 | yahK | b0325 JW0317 | cytoplasmic peripheral IM protein, Aldehyde reductase YahK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | no | yes | No | 53 | 0.148 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 73 | |||||||||
| ADHE_ECOLI | P0A9Q7 | adhE ana | ana | b1241 JW1228 | cytoplasmic peripheral IM protein, Aldehyde-alcohol dehydrogenase AdhE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 56 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 45 | |||||||
| SSUB_ECOLI | P0AAI1 | ssuB ycbE | ycbE | b0933 JW0916 | cytoplasmic peripheral IM protein, Aliphatic sulfonates import ATP-binding SsuB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 22 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 23 | ||||||||||
| AHPC_ECOLI | P0AE08 | ahpC | b0605 JW0598 | cytoplasmic peripheral IM protein, Alkyl hydroperoxide reductase C AhpC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bridge (47 47;166 166) Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 49 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 90 | ||||||||
| AHPF_ECOLI | P35340 | ahpF | b0606 JW0599 | cytoplasmic peripheral IM protein, Alkyl hydroperoxide reductase subunit F AhpF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Disulfide bridge (345 348) | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 35 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 76 | |||||||||
| PHNL_ECOLI | P16679 | phnL | b4096 JW4057 | cytoplasmic peripheral IM protein, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 34 | 0.263 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 8 | ||||||||||
| UXAA_ECOLI | P42604 | uxaA ygjW | ygjW | b3091 JW3062 | cytoplasmic peripheral IM protein, Altronate dehydratase UxaA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 68 | 0.185 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 113 | |||||||||
| PUR1_ECOLI | P0AG16 | purF | b2312 JW2309 | cytoplasmic peripheral IM protein, Amidophosphoribosyltransferase PurF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 32 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||||
| YHDZ_ECOLI | P45769 | yhdZ | b3271 JW3239 | cytoplasmic peripheral IM protein, amino-acid ABC transporter ATP-binding YhdZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 12 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 11 | |||||||||||
| GCST_ECOLI | P27248 | gcvT | b2905 JW2873 | cytoplasmic peripheral IM protein, Aminomethyltransferase GcvT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 31 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 101 | ||||||||||
| AMPN_ECOLI | P04825 | pepN | b0932 JW0915 | cytoplasmic peripheral IM protein, Aminopeptidase PepN | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homologous peptidases are membrane associated in mammals, some data propose that the enzyme may associate with the E.coli membrane. It is structurally classified with <a href="http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/enzymes/GetPage.pl?ec_number=3.4.11.2">EC 3.4.11.2</a> membrane alanyl aminopeptidases. However, the extent of membrane association needs further analysis as it is generally soluble in the cytoplasmic fraction of E.coli and other bacteria. PMID: 323010 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 323010 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side | Cytoplasmic (Experimental) | N/A | yes | yes | No | 50 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 101 | ||||||||
| GLPA_ECOLI | P0A9C0 | glpA | b2241 JW2235 | cytoplasmic peripheral IM protein, Anaerobic glycerol-3-phosphate dehydrogenase subunit A GlpA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Confirmed cytoplasmic membrane localization of GlpB. GlpB has been isolated from inner membrane preparations. Part of anaerobic glycerol-3-phosphate dehydrogenase composed of a catalytic GlpA/B dimer and of membrane bound GlpC. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 62 | 0.155 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 5 | |||||||||
| GLPB_ECOLI | P13033 | glpB | b2242 JW2236 | cytoplasmic peripheral IM protein, Anaerobic glycerol-3-phosphate dehydrogenase subunit B GlpB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Confirmed cytoplasmic membrane localization of GlpB. GlpB has been isolated from inner membrane preparations. Part of anaerobic glycerol-3-phosphate dehydrogenase composed of a catalytic GlpA/B dimer and of membrane bound GlpC. GlpD enzyme is membrane bound. The active site has been located at the cytoplasmic (inner) face of the membrane. PMID: 6387427 Glycerol-P dehydrogenase is a primary dehydrogenase in the electron transport chain. It functions in vitro only when associated with the cytoplasmic membrane. The enzyme has been purified from the membrane fraction after solubilization with deoxycholate. PMID: 1987111 PMCID: PMC3210124 PMID: 3286606 | PMID: 1987111 PMID: 20706981 PMID: 3286606 PMID: 6387427 PMCID: PMC3210124 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic (Experimental) | IM (predicted) | yes | yes | No | 30 | 0.137 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n10-21c28/29o | CytoplasmicMembrane | 10 | 24 | ||||||||
| GLPC_ECOLI | P0A996 | glpC | b2243 JW2237 | cytoplasmic peripheral IM protein, Anaerobic glycerol-3-phosphate dehydrogenase subunit C GlpC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Confirmed cytoplasmic membrane localization of GlpB. GlpB has been isolated from inner membrane preparations. Part of anaerobic glycerol-3-phosphate dehydrogenase composed of a catalytic GlpA/B dimer and of membrane bound GlpC. PMID: 3286606 | PMID: 3286606 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Membrane associated (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 35 | 0.222 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 13 | ||||||||
| TRPE_ECOLI | P00895 | trpE | b1264 JW1256 | cytoplasmic peripheral IM protein, Anthranilate synthase component 1 TrpE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 19 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 66 | |||||||||
| ARAG_ECOLI | P0AAF3 | araG | b1900 JW1888 | cytoplasmic peripheral IM protein, Arabinose import ATP-binding AraG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 7028715 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 38 | 0.293 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 37 | |||||||||
| ARTP_ECOLI | P0AAF6 | artP | b0864 JW0848 | cytoplasmic peripheral IM protein, Arginine transport ATP-binding ArtP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | The artPIQM artJ genes encode a third arginine-uptake system in addition to the known argT hisJQMP system of Salmonella typhimurium and E. coli and the arginine (-ornithine) carrier (aps) of E. coli. The artQ, artM and artP products are similar to the transmembraneous proteins and the ATPase of binding-protein-dependent carriers. PMID: 8801422 PMID: 8801422 PMID: 15758229 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15758229 PMID: 23230279 PMID: 8801422 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 26 | ||||||||
| ARLY_ECOLI | P11447 | argH | b3960 JW3932 | cytoplasmic peripheral IM protein, Argininosuccinate lyase ArgH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 53 | 0.138 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| ASSY_ECOLI | P0A6E4 | argG | b3172 JW3140 | cytoplasmic peripheral IM protein, Argininosuccinate synthase ArgG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 37 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 19 | |||||||||
| ULAC_ECOLI | P69820 | ulaC ptxA sgaA yjfU | ptxA sgaA yjfU | b4195 JW4153 | cytoplasmic peripheral IM protein, Ascorbate-specific PTS system EIIA component UlaC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | PMID: 12644495 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 47 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 84 | ||||||||
| ULAB_ECOLI | P69822 | ulaB sgaB yjfT | sgaB yjfT | b4194 JW4152 | cytoplasmic peripheral IM protein, Ascorbate-specific PTS system EIIB component UlaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | The sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment (12 TMS) transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system (PTS), respectivelyPMID: 12644495. All three proteins are required for the anaerobic utilization and uptake of L-ascorbate in vivo and its phosphoenolpyruvate-dependent phosphorylation in vitroPMID: 12644495. | PMID: 12644495 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 62 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 53 | |||||||
| ASNB_ECOLI | P22106 | asnB | b0674 JW0660 | cytoplasmic peripheral IM protein, Asparagine synthetase B AsnB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 37 | 0.141 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| SYN_ECOLI | P0A8M0 | asnS tss | tss | b0930 JW0913 | cytoplasmic peripheral IM protein, Asparagine--tRNA ligase AsnS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit. Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 53 | 0.182 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 70 | ||||||
| AAT_ECOLI | P00509 | aspC | b0928 JW0911 | cytoplasmic peripheral IM protein, Aspartate aminotransferase AspC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 PMID: 3521591 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | yes | yes | No | 23 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||
| ASPA_ECOLI | P0AC38 | aspA | b4139 JW4099 | cytoplasmic peripheral IM protein, Aspartate ammonia-lyase AspA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Detected with chromosomally tap-tagged TF with >80% confidence score PMID: 15690043 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 22 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 87 | ||||||||
| SYD_ECOLI | P21889 | aspS tls | tls | b1866 JW1855 | cytoplasmic peripheral IM protein, Aspartate--tRNA ligase AspS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | SecY-interacting protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19139097 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 27 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 81 | |||||||
| DHAS_ECOLI | P0A9Q9 | asd hom | hom | b3433 JW3396 | cytoplasmic peripheral IM protein, Aspartate-semialdehyde dehydrogenase Asd | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 44 | 0.197 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | ||||||||
| HIS1_ECOLI | P60757 | hisG | b2019 JW2001 | cytoplasmic peripheral IM protein, ATP phosphoribosyltransferase HisG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 44 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 64 | |||||||||
| ATPE_ECOLI | P0A6E6 | atpC papG uncC | papG uncC | b3731 JW3709 | cytoplasmic peripheral IM protein, ATP synthase epsilon chain AtpC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 16079137 PMID: 21778229 PMID: 23230279 PMID: 9868784 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 41 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 120 | ||||||||
| ATPG_ECOLI | P0ABA6 | atpG papC uncG | papC uncG | b3733 JW3711 | cytoplasmic peripheral IM protein, ATP synthase gamma chain AtpG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 PMID: 7508444 PMID: 2900236 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16079137 PMID: 23230279 PMID: 2900236 PMID: 7508444 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 41 | 0.162 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 48 | |||||||
| ATPA_ECOLI | P0ABB0 | atpA papA uncA | papA uncA | b3734 JW3712 | cytoplasmic peripheral IM protein, ATP synthase subunit alpha AtpA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Exhibites aberrant localization by microscopy in the absence of YidC. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | IM (predicted) | TF | no | yes | No | 28 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 60 | ||||||
| ATPB_ECOLI | P0ABB4 | atpD papB uncD | papB uncD | b3732 JW3710 | cytoplasmic peripheral IM protein, ATP synthase subunit beta AtpD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Exhibites aberrant localization by microscopy in the absence of YidC. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 23 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 77 | |||||||
| ATPD_ECOLI | P0ABA4 | atpH papE uncH | papE uncH | b3735 JW3713 | cytoplasmic peripheral IM protein, ATP synthase subunit delta AtpH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 36 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 89 | |||||||
| PFKA_ECOLI | P0A796 | pfkA | b3916 JW3887 | cytoplasmic peripheral IM protein, ATP-dependent 6-phosphofructokinase isozyme 1 PfkA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 20 | 0.426 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 76 | |||||||||
| HSLU_ECOLI | P0A6H5 | hslU htpI | htpI | b3931 JW3902 | cytoplasmic peripheral IM protein, ATP-dependent protease ATPase subunit HslU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 24 | 0.141 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 74 | ||||||||
| DBPA_ECOLI | P21693 | dbpA | b1343 JW1337 | cytoplasmic peripheral IM protein, ATP-dependent RNA helicase DbpA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; Fragment of 23S rRNA. Assembly cofactor of ribosome; Fragment of 23S rRNA. PMID: 21529161 | PMID: 21529161 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 32 | 0.341 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 12 | ||||||||
| DEAD_ECOLI | P0A9P6 | deaD csdA mssB rhlD | csdA mssB rhlD | b3162 JW5531 | cytoplasmic peripheral IM protein, ATP-dependent RNA helicase DeaD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation PMID: 19737520. Contains a SPOR domain. PMID: 8552679 | PMID: 19880599 PMID: 23230279 PMID: 8552679 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 35 | 0.151 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 50 | ||||||
| HRPA_ECOLI | P43329 | hrpA | b1413 JW5905 | cytoplasmic peripheral IM protein, ATP-dependent RNA helicase HrpA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 52 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||||
| RHLE_ECOLI | P25888 | rhlE | b0797 JW0781 | cytoplasmic peripheral IM protein, ATP-dependent RNA helicase RhlE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; associates with the 70S subunit. Overex<x>pression of protein suppresses defects in deletion of DeaD. PMID: 18083833 | PMID: 18083833 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 46 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | ||||||||
| SRMB_ECOLI | P21507 | srmB rbaB rhlA | rbaB rhlA | b2576 JW2560 | cytoplasmic peripheral IM protein, ATP-dependent RNA helicase SrmB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; associate with the 50S subunit. | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 33 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 68 | |||||||
| LSRA_ECOLI | P77257 | lsrA ego ydeX | ego ydeX | b1513 JW1506 | cytoplasmic peripheral IM protein, Autoinducer 2 import ATP-binding LsrA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | no | yes | No | 42 | 0.176 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 17 | ||||||||||
| GRCA_ECOLI | P68066 | grcA yfiD | yfiD | b2579 JW2563 | cytoplasmic peripheral IM protein, Autonomous glycyl radical cofactor GrcA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 30 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| AZUC_ECOLI | C1P605 | azuC | b4663 JW1891.1 | cytoplasmic peripheral IM protein, AzuC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Small protein detected experimentally. AzuC-SPA was most abundant in the inner membrane fraction (77%) indicating this protein is bound to the cytoplasmic side of the inner membrane. | PMID: 19121005 PMID: 21778229 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | - | N/A | no | yes | No | 27 | 0.099 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||
| FTNB_ECOLI | P0A9A2 | ftnB yecI | yecI | b1902 JW1890 | cytoplasmic peripheral IM protein, Bacterial non-heme ferritin-like protein FtnB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 48 | 0.152 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 82 | |||||||
| WBBI_ECOLI | P37749 | wbbI yefG | yefG | b2034 JW2019 | cytoplasmic peripheral IM protein, Beta-1,6-galactofuranosyltransferase WbbI WbbI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 42 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 14 | |||||||
| BGLR_ECOLI | P05804 | uidA gurA gusA | gurA gusA | b1617 JW1609 | cytoplasmic peripheral IM protein, Beta-glucuronidase UidA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 59 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 46 | ||||||||
| AK1H_ECOLI | P00561 | thrA thrA1 thrA2 | thrA1 thrA2 | b0002 JW0001 | cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 1 ThrA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Copurifies with trigger factor in pull down assays. Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 4562989 PMID: 354697 PMID: 7003595 PMID: 6777249 | PMID: 15911532 PMID: 354697 PMID: 4562989 PMID: 6777249 PMID: 7003595 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | TF | yes | yes | No | 15 | 0.142 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||
| AK2H_ECOLI | P00562 | metL metM | metM | b3940 JW3911 | cytoplasmic peripheral IM protein, Bifunctional aspartokinase/homoserine dehydrogenase 2 MetL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 24 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | |||||||||
| GLMU_ECOLI | P0ACC7 | glmU yieA | yieA | b3730 JW3708 | cytoplasmic peripheral IM protein, Bifunctional GlmU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 49 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 94 | ||||||||
| ARNA_ECOLI | P77398 | arnA pmrI yfbG | pmrI yfbG | b2255 JW2249 | cytoplasmic peripheral IM protein, Bifunctional polymyxin resistance ArnA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 59 | 0.178 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 3 | |||||||||
| TRPGD_ECOLI | P00904 | trpGD trpD | trpD | b1263 JW1255 | cytoplasmic peripheral IM protein, Bifunctional TrpG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Could not obtain any evidence for membrane binding (F1) Peripheral IM Cytoplasmic side. Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 4594441 PMID: 6283099 | PMID: 15911532 PMID: 19766000 PMID: 4594441 PMID: 6283099 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 19 | 0.166 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 22 | ||||||||
| ACCC_ECOLI | P24182 | accC fabG | fabG | b3256 JW3224 | cytoplasmic peripheral IM protein, Biotin carboxylase AccC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation PMID: 19737520. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 36 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 29 | |||||||
| ARCM_ECOLI | P77624 | yahI | b0323 JW0315 | cytoplasmic peripheral IM protein, Carbamate kinase-like YahI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 82 | |||||||||
| CARB_ECOLI | P00968 | carB pyrA | pyrA | b0033 JW0031 | cytoplasmic peripheral IM protein, Carbamoyl-phosphate synthase large chain CarB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 24 | 0.228 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n9-16c21/22o | Unknown | 4 | ||||||||
| CARA_ECOLI | P0A6F1 | carA pyrA | pyrA | b0032 JW0030 | cytoplasmic peripheral IM protein, Carbamoyl-phosphate synthase small chain CarA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 22 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 60 | |||||||
| CLSB_ECOLI | P0AA84 | clsB ybhO | ybhO | b0789 JW0772 | cytoplasmic peripheral IM protein, Cardiolipin synthase B ClsB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | In E. coli, the cls and ybhO genes (renamed clsA and clsB, respectively) each encode a CL (cardiolipin) synthase (Cls) that catalyzes the condensation of two PG molecules to form CL and glycerol. PMID: 22988102 | PMID: 22988102 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | yes | yes | No | 66 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 27 | |||||||
| PSS_ECOLI | P23830 | pssA pss | pss | b2585 JW2569 | cytoplasmic peripheral IM protein, CDP-diacylglycerol--serine O-phosphatidyltransferase PssA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Phospholipid metabolism complex PlsB-PssA-YbgC-Acp. Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm Cell inner membrane; Peripheral membrane protein; Cytoplasmic side | Cytoplasmic | N/A | TF | yes | yes | No | 48 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 35 | ||||||
| LIT_ECOLI | P11072 | lit | b1139 JW1125 | cytoplasmic peripheral IM protein, Cell death peptidase Lit | Single weak hydrophobic region. Could be a transmembrane domain but could also be a peripheral inner membrane protein. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | no | no | No | 20 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i61-81o | Cytoplasmic | 8 | ||||||||||
| FTSE_ECOLI | P0A9R7 | ftsE | b3463 JW3428 | cytoplasmic peripheral IM protein, Cell division ATP-binding FtsE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homolog to import ATP-binding protein MalK. Is the putative ATP-binding protein component of an ATP-binding cassette (ABC) transporter. FtsE dimerizes and associates with the inner membrane via interaction with FtsX, an integral membrane protein. FtsE dimerizes and associates with the inner membrane via interaction with FtsX, an integral membrane protein. PMID: 10048040 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10048040 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 32 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 11 | ||||||||
| FTSA_ECOLI | P0ABH0 | ftsA divA | divA | b0094 JW0092 | cytoplasmic peripheral IM protein, Cell division FtsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | FtsA has a conserved C-terminal membrane targeting sequence (MTS) with extremely weak TmHMM and Phobius predictions. Deletion or point mutations in the MTS, inactivate FtsA function and inhibit cell division. Because FtsA binds to the tubulin-like FtsZ protein that forms the Z ring, it is thought that the MTS of FtsA is required, along with the transmembrane protein ZipA, to assemble the Z ring and anchor it to the cytoplasmic membrane. FtsA function in cell division depends on additive effects of membrane binding and self-interaction, and that the specific requirement of an amphipathic helix for tethering FtsA to the membrane can be bypassed. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 18186792 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 25 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 84 | |||||||
| FTSZ_ECOLI | P0A9A6 | ftsZ sfiB sulB | sfiB sulB | b0095 JW0093 | cytoplasmic peripheral IM protein, Cell division FtsZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. Assembles at midcell at the inner surface of the cytoplasmic membrane. SulA halts cell division in Escherichia coli by binding to the major component of the division machinery FtsZ. PMID: 8917533 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Over-expression of NlpI can interrupt the nucleoids division and the assembly of FtsZ at the septum, mediated by IbpA/IbpB, suggesting a role of the NlpI/IbpA/IbpB complex in the cell division. PMID: 25699035 | PMID: 1944597 PMID: 20497333 PMID: 23230279 PMID: 25699035 PMID: 8917533 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 26 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 79 | |||||||
| MINE_ECOLI | P0A734 | minE | b1174 JW1163 | cytoplasmic peripheral IM protein, Cell division topological specificity factor MinE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | MinD recruits MinC to the membrane to form the MinC-MinD complex, which inhibits septum formation, and MinE acts to localize and restrict inhibition to the inappropriate septation sites. The N-Terminal Amphipathic Helix of the Topological Specificity Factor MinE Is Associated with Shaping Membrane Curvature. PMID: 21738659 | PMID: 10096083 PMID: 20025670 PMID: 21738659 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 18 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 101 | |||||||||
| ZAPA_ECOLI | P0ADS2 | zapA ygfE | ygfE | b2910 JW2878 | cytoplasmic peripheral IM protein, Cell division ZapA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Binds to the FtsZ ring. ZapA interacts directly with itself, FtsN, FtsZ and FtsI. Peripheral inner membrane protein via binding to the FtsZ ring. ZapA orthologue, YgfE, binds FtsZ polymers and promotes FtsZ polymer bundling. PMID: 12368265 | PMID: 12368265 PMID: 17428494 PMID: 20487275 PMID: 20497333 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 67 | 0.152 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 97 | |||||||
| ZAPB_ECOLI | P0AF36 | zapB yiiU | yiiU | b3928 JW3899 | cytoplasmic peripheral IM protein, Cell division ZapB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 18394147 PMID: 20487275 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 19 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 81 | ||||||||
| ZAPD_ECOLI | P36680 | zapD yacF | yacF | b0102 JW0099 | cytoplasmic peripheral IM protein, Cell division ZapD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. 22505682 | 22505682 PMID: 22505682 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 39 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 80 | |||||||
| MREB_ECOLI | P0A9X4 | mreB envB rodY | envB rodY | b3251 JW3220 | cytoplasmic peripheral IM protein, Cell shape-determining MreB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Bacterial actin homologue; is required for cell shape maintenance in most non-spherical bacteria, where it assembles into helical structures just underneath the cytoplasmic membrane; binds to the bitopic inner membrane protein RodZ as monomer or multimer. Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. PMID: 19737520 PBP-5 deletion mutants exhibit irregular distribution of MreB at the deformed zones. [PBP deletion mutants of Escherichia coli exhibit irregular distribution of MreB at the deformed zones. PMID: 24057063 PMID: 17090951 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16391237 PMID: 17090951 PMID: 19008860 PMID: 19078962 PMID: 20168300 PMID: 21816350 PMID: 23230279 PMID: 24057063 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 41 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | |||||||
| CLPB_ECOLI | P63284 | clpB htpM | htpM | b2592 JW2573 | cytoplasmic peripheral IM protein, Chaperone ClpB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 PMID: 8376377 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 75 | ||||||||
| DNAJ_ECOLI | P08622 | dnaJ groP | groP | b0015 JW0014 | cytoplasmic peripheral IM protein, Chaperone DnaJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Interacts with DmsD is a redox enzyme maturation protein (REMP). PMID: 20153451 | PMID: 20153451 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 39 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 52 | |||||||
| HTPG_ECOLI | P0A6Z3 | htpG | b0473 JW0462 | cytoplasmic peripheral IM protein, Chaperone HtpG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 43 | 0.189 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 109 | ||||||||
| YCDY_ECOLI | P75915 | ycdY | b1035 JW1018 | cytoplasmic peripheral IM protein, Chaperone YcdY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 38 | 0.184 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 89 | ||||||||||
| CHEA_ECOLI | P07363 | cheA | b1888 JW1877 | cytoplasmic peripheral IM protein, Chemotaxis CheA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted), Soluble IM Fraction + | no | yes | No | 17 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 88 | |||||||||
| CISY_ECOLI | P0ABH7 | gltA gluT icdB | gluT icdB | b0720 JW0710 | cytoplasmic peripheral IM protein, Citrate synthase GltA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 43 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 22 | |||||||
| CAIC_ECOLI | P31552 | caiC yaaM | yaaM | b0037 JW0036 | cytoplasmic peripheral IM protein, Crotonobetaine/carnitine--CoA ligase CaiC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to FadD13 protein of Mycobacterium that is peripheral. | PMID: 22560731 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 18 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| BGLG_ECOLI | P11989 | bglG bglC | bglC | b3723 JW3701 | cytoplasmic peripheral IM protein, Cryptic beta-glucoside bgl operon antiterminator BglG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | BglG is a transcriptional antiterminator which controls the expression bgl operon. It has been detected at the membrane when it is expressed with BglF, when expressed as monocistron, the bglG transcripts were observed at the cell poles (unpublished data). In the absence of ??-glucosidase, BglG also assembles near membrane and forms a pro-form complex with BglF that maintains BglG inactive. In the presence of sugar, BglG associates with the proteins of the sugar phosphotransfer system (PTS) and localizes at the cell poles. BglG requires two distinct (de)phosphorylation events to gain activity. | PMID: 22984181 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 38 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 48 | ||||||||
| PYRG_ECOLI | P0A7E5 | pyrG | b2780 JW2751 | cytoplasmic peripheral IM protein, CTP synthase PyrG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PyrG=CTP synthase or CtpS in some systems. CTP synthase forms filaments in Caulobacter crescentus that regulate cell curvature independently of its catalytic function. The morphogenic role of CtpS requires its functional interaction with the intermediate filament, crescentin (CreS). Trigger factor-sensitive aggregation. PMID: 19737520 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 20639870 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | TF | yes | yes | No | 27 | 0.24 | SpI | 26 | 1.52462 | - | 1 | 0 | N | i | Cytoplasmic | 9 | 77 | ||||||||
| CFA_ECOLI | P0A9H7 | cfa cdfA | cdfA | b1661 JW1653 | cytoplasmic peripheral IM protein, Cyclopropane-fatty-acyl-phospholipid synthase Cfa | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Exhibites aberrant localization by microscopy in the absence of YidC. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 38 | 0.183 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 26 | |||||||
| CSDA_ECOLI | Q46925 | csdA ygdJ | ygdJ | b2810 JW2781 | cytoplasmic peripheral IM protein, Cysteine desulfurase CsdA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Assembly cofactor of ribosome; associate with the 50S subunit. Under cold-shock conditions CsdA participates as an alternative DEAD-box RNA helicase together with RNase E in a ???cold shock??? RNA degradosome (Prud???homme-Genereux et al., 2004). It is therefore possible that CsdA may associate with the inner membrane via RNAseE. | PMID: 15554978 PMID: 21529161 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 59 | 0.194 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | ||||||||
| ISCS_ECOLI | P0A6B7 | iscS nuvC yfhO yzzO | nuvC yfhO yzzO | b2530 JW2514 | cytoplasmic peripheral IM protein, Cysteine desulfurase IscS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | IscS is critical for iron-sulfur (Fe-S) cluster formation and repair. IscS transfers sulfur to the coregulated "scaffold" protein IscU (NifU), on which Fe-S clusters are assembled. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 48 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 37 | |||||||
| SUFS_ECOLI | P77444 | sufS csdB ynhB | csdB ynhB | b1680 JW1670 | cytoplasmic peripheral IM protein, Cysteine desulfurase SufS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | SufE protein and the SufBCD complex stimulate the sulfurylase activity of SufS probably through direct interaction. | PMID: 12941942 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 66 | 0.18 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 11 | |||||||
| SUFE_ECOLI | P76194 | sufE ynhA | ynhA | b1679 JW1669 | cytoplasmic peripheral IM protein, Cysteine desulfuration SufE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | SufE protein and the SufBCD complex stimulate the sulfurylase activity of SufS. Probably through direct interaction . | PMID: 12941942 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 66 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 104 | |||||||
| CYSK_ECOLI | P0ABK5 | cysK cysZ | cysZ | b2414 JW2407 | cytoplasmic peripheral IM protein, Cysteine synthase A CysK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 31 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 77 | |||||||
| CCMA_ECOLI | P33931 | ccmA yejW | yejW | b2201 JW5366 | cytoplasmic peripheral IM protein, Cytochrome c biogenesis ATP-binding export CcmA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 29 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 47 | ||||||||||
| AMPA_ECOLI | P68767 | pepA carP xerB | carP xerB | b4260 JW4217 | cytoplasmic peripheral IM protein, Cytosol aminopeptidase PepA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 35 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 58 | |||||||||
| ALSA_ECOLI | P32721 | alsA yjcW | yjcW | b4087 JW4048 | cytoplasmic peripheral IM protein, D-allose import ATP-binding AlsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 21 | 0.291 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 18 | ||||||||||
| DADA_ECOLI | P0A6J5 | dadA dadR | dadR | b1189 JW1178 | cytoplasmic peripheral IM protein, D-amino acid dehydrogenase DadA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. Exhibites aberrant localization by microscopy in the absence of YidC. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 6102989 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 23 | 0.155 | TMH | 0 | 0.264511 | - | 0 | 0 | Y | n3-11c16/17o | CytoplasmicMembrane | 10 | 12 | ||||||
| GATY_ECOLI | P0C8J6 | gatY yegF | yegF | b2096 JW5343 | cytoplasmic peripheral IM protein, D-tagatose-1,6-bisphosphate aldolase subunit GatY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 49 | 0.137 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | |||||||
| GATZ_ECOLI | P0C8J8 | gatZ | b2095 JW2082 | cytoplasmic peripheral IM protein, D-tagatose-1,6-bisphosphate aldolase subunit GatZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Encoded in the phosphotransferase transport system the hexitol galactitol (Gat), binds to the gatY protein that encodes for a D-tagatose-1,6-bisphosphate aldolase. Trigger factor-sensitive aggregation. Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 33 | 0.318 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 6 | ||||||||
| DEOC_ECOLI | P0A6L0 | deoC dra thyR | dra thyR | b4381 JW4344 | cytoplasmic peripheral IM protein, Deoxyribose-phosphate aldolase DeoC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 115 | ||||||||
| YIHI_ECOLI | P0A8H6 | yihI | b3866 JW3837 | cytoplasmic peripheral IM protein, Der GTPase-activating YihI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; associates with Der. | PMID: 21529161 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 43 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 108 | |||||||||
| PYRD_ECOLI | P0A7E1 | pyrD | b0945 JW0928 | cytoplasmic peripheral IM protein, Dihydroorotate dehydrogenase PyrD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 45 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 12 | ||||||||
| ILVD_ECOLI | P05791 | ilvD | b3771 JW5605 | cytoplasmic peripheral IM protein, Dihydroxy-acid dehydratase IlvD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 54 | 0.166 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 25 | ||||||||||
| DLDH_ECOLI | P0A9P0 | lpdA lpd | lpd | b0116 JW0112 | cytoplasmic peripheral IM protein, Dihydroyl dehydrogenase LpdA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. PMID: 6352260 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Disulfide bridge (45 50) Disulfide bond-containing protein PMID: 25664544 | PMID: 16079137 PMID: 23230279 PMID: 6352260 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 23 | 0.176 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 79 | ||||||
| ODP2_ECOLI | P06959 | aceF | b0115 JW0111 | cytoplasmic peripheral IM protein, Dihydroyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex AceF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15911532 PMID: 15919657 PMID: 23230279 PMID: 24742683 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | no | yes | No | 52 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 95 | ||||||||
| ODO2_ECOLI | P0AFG6 | sucB | b0727 JW0716 | cytoplasmic peripheral IM protein, Dihydroyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. PMID: 9298646 | PMID: 15919657 PMID: 23230279 PMID: 9298646 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 19 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 122 | ||||||||
| DPPD_ECOLI | P0AAG0 | dppD | b3541 JW3510 | cytoplasmic peripheral IM protein, Dipeptide transport ATP-binding DppD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 66 | 0.286 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 19 | ||||||||
| DPPF_ECOLI | P37313 | dppF dppE | dppE | b3540 JW3509 | cytoplasmic peripheral IM protein, Dipeptide transport ATP-binding DppF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 53 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 24 | |||||||
| YGHU_ECOLI | Q46845 | yghU | b2989 JW5492 | cytoplasmic peripheral IM protein, Disulfide-bond oxidoreductase YghU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Phobius gives a large hydrophobic stretch that is not too hydrophobic to be a real TM. hydropathy profile also shows hydrophobic strecthes. localization peripheral inner membrane protein possibly also integral inner membrane/phobius gives a large hydrophobic stretch that is not too hydrophobic to be a real TM. hydropathy profile also shows hydrophobic strecthes. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Membrane anchored | N/A | yes | yes | No | 24 | 0.332 | CYT | 0 | -0.200913 | - | 1 | 0 | N | i | Cytoplasmic | 9 | 49 | |||||||||
| LEPA_ECOLI | P60785 | lepA | b2569 JW2553 | cytoplasmic peripheral IM protein, Elongation factor 4 LepA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | LepA has an amino-terminal domain of 112 residues that is homologous to a domain of similar size found in initiation factor 2, elongation factor Tu, and elongation factor G (IF2, EF-Tu, and EF-G). GTP-photoaffinity labeling and subcellular fractionation experiments indicate that LepA a membrane-bound GTP-binding protein PMID: 2999765. GTPase, EF4/LepA involved in translational elongation, EF4 is stored at the membrane of Escherichia coli cells and released into the cytoplasm upon conditions of high ionic strength or low temperature where EF4 binds to stalled ribosomes and remobilizes themPMID: 21300907.Trigger factor-sensitive aggregationPMID: 19737520. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 21300907 PMID: 23230279 PMID: 2999765 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 39 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 45 | |||||||
| EFG_ECOLI | P0A6M8 | fusA far fus | far fus | b3340 JW3302 | cytoplasmic peripheral IM protein, Elongation factor G FusA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation PMID: 7042386 | PMID: 23230279 PMID: 7042386 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | yes | yes | No | 39 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | |||||||
| EFTS_ECOLI | P0A6P1 | tsf | b0170 JW0165 | cytoplasmic peripheral IM protein, Elongation factor Ts Tsf | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 59 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 87 | ||||||||
| EFTU1_ECOLI | P0CE47 | tufA | b3339 JW3301 | cytoplasmic peripheral IM protein, Elongation factor Tu 1 TufA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Translation initiation factor EF-Tu. Ribosome association and peripheral inner membrane protein. In B. subtilis EF-Tu localizes in a helical pattern underneath the cell membrane and colocalizes with MreB, an actin-like cytoskeletal. PMID: 7525272 PMID: 7021545 Interacts with DmsD is a redox enzyme maturation protein (REMP). PMID: 20153451 Disulfide bond-containing protein PMID: 25664544 | PMID: 20133608 PMID: 20153451 PMID: 2022614 PMID: 7021545 PMID: 7525272 PMID: 775340 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm Cell inner membrane; Peripheral membrane protein | Cytoplasmic (Experimental) | N/A | yes | yes | No | 47 | 0.197 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 99 | ||||||||
| EFTU2_ECOLI | P0CE48 | tufB | b3980 JW3943 | cytoplasmic peripheral IM protein, Elongation factor Tu 2 TufB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 20153451 PMID: 2022614 PMID: 23230279 PMID: 775340 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 47 | 0.197 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 87 | |||||||||
| ETTA_ECOLI | P0A9W3 | ettA yjjK | yjjK | b4391 JW4354 | cytoplasmic peripheral IM protein, Energy-dependent translational throttle EttA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homolog to import ATP-binding protein MalK. Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 43 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | ||||||
| FABI_ECOLI | P0AEK4 | fabI envM | envM | b1288 JW1281 | cytoplasmic peripheral IM protein, Enoyl-(acyl-carrier-protein) reductase (NADH) FabI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 28 | 0.245 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 48 | |||||||
| ENTB_ECOLI | P0ADI4 | entB entG | entG | b0595 JW0587 | cytoplasmic peripheral IM protein, Enterobactin synthase component B EntB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 10692387 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 26 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 65 | ||||||||
| ENTE_ECOLI | P10378 | entE | b0594 JW0586 | cytoplasmic peripheral IM protein, Enterobactin synthase component E EntE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Homologous to FadD13 protein of Mycobacterium that is peripheral. Phobius predits transmembrane region around aa100. Binds AMP. Very high homology to eight other transport proteins: (FADK_ECOLI, CAIC_ECOLI, LCFA_ECOLI, ENTF_ECOLI, ACSA_ECOLI) Membrane Association of the Escherichia coli Enterobactin Synthase Proteins EntB/G, EntE, and EntF | PMID: 10692387 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Membrane | Cytoplasmic | N/A | yes | yes | No | 36 | 0.15 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o86-105i | Cytoplasmic | 9 | 88 | ||||||||
| ENTF_ECOLI | P11454 | entF | b0586 JW0578 | cytoplasmic peripheral IM protein, Enterobactin synthase component F EntF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 10692387 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 56 | 0.235 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 20 | ||||||||||
| PPX_ECOLI | P0AFL6 | ppx | b2502 JW2487 | cytoplasmic peripheral IM protein, Exopolyphosphatase Ppx | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | IM (predicted) | yes | yes | No | 29 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 47 | ||||||||
| FADB_ECOLI | P21177 | fadB oldB | oldB | b3846 JW3822 | cytoplasmic peripheral IM protein, Fatty acid oxidation complex subunit alpha FadB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 31 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||
| FADJ_ECOLI | P77399 | fadJ yfcX | yfcX | b2341 JW2338 | cytoplasmic peripheral IM protein, Fatty acid oxidation complex subunit alpha FadJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 70 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | ||||||||
| FDRA_ECOLI | Q47208 | fdrA ylbD | ylbD | b0518 JW0506 | cytoplasmic peripheral IM protein, FdrA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 7500942 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Integral Membrane Protein | N/A | yes | yes | No | 31 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 56 | ||||||||
| FECE_ECOLI | P15031 | fecE | b4287 JW4247 | cytoplasmic peripheral IM protein, Fe(3+) dicitrate transport ATP-binding FecE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 62 | 0.148 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 4 | |||||||||||
| FBPC_ECOLI | P37009 | fbpC afuC yagC | afuC yagC | b0262 JW0254 | cytoplasmic peripheral IM protein, Fe(3+) ions import ATP-binding FbpC | Homologous to MalK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | yes | no | No | 62 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 42 | ||||||||
| YDHY_ECOLI | P0AAL6 | ydhY | b1674 JW1664 | cytoplasmic peripheral IM protein, Ferredoxin-like YdhY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 28 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | ||||||||||
| FEPC_ECOLI | P23878 | fepC | b0588 JW0580 | cytoplasmic peripheral IM protein, Ferric enterobactin transport ATP-binding FepC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 63 | 0.171 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 17 | |||||||||||
| FHUF_ECOLI | P39405 | fhuF yjjS | yjjS | b4367 JW4331 | cytoplasmic peripheral IM protein, Ferric iron reductase FhuF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | It has a large transmembrane helix in the middle. | PMID: 14756576 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm Cell membrane; Peripheral membrane protein | Cytoplasmic | IM (predicted) | yes | yes | No | 55 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 1 | N | i91-112o | Cytoplasmic | 10 | 29 | |||||||
| HEMH_ECOLI | P23871 | hemH popA visA | popA visA | b0475 JW0464 | cytoplasmic peripheral IM protein, Ferrochelatase HemH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 63 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 15 | ||||||||
| SUFB_ECOLI | P77522 | sufB ynhE | ynhE | b1683 JW5273 | cytoplasmic peripheral IM protein, FeS cluster assembly SufB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Completely soluble no evidence for hyrophobic patches. IM binding determined by immunolocalization. | PMID: 11943156 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 31 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 43 | ||||||||
| SUFD_ECOLI | P77689 | sufD ynhC | ynhC | b1681 JW1671 | cytoplasmic peripheral IM protein, FeS cluster assembly SufD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Forms complex with SufC and SufB. | PMID: 10322040 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 67 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 36 | ||||||||
| FIXC_ECOLI | P68644 | fixC yaaS | yaaS | b0043 JW0042 | cytoplasmic peripheral IM protein, FixC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | The protein has hydrophobic patches all over it's sequence. Could be part of an electron transfer system required for anaerobic carnitine reduction so this is consistent with a membrane association. Strong Prediction on both Phobius and TMHMM for an aminoterminal weakly hydrophobic region. Other studies propose that this sequence may be an aminoterminal signal peptide without evidence for cleavage. The fixABCX genes in Rhodospirillum Rubrum encode a putative membrane complex participating in electron transfer to nitrogenase where FixA and B are soluble proteins.However the RrFixC expressed in E.coli was localized at the membrane fraction and was not carbonate extracted suggesting that it is an integral membrane protein. From another study in Rhizobia. Primary sequence homology, the FixC family is a highly conserved flavoprotein distantly related to the mitochondrial ETF-QO (peripheral, membrane-associated ETF : ubiquinone oxidoreductase) yet lacking both hydrophobic and amphipathic transmembrane {alpha}-helices. Thus FixC family is unlikely to be stably membrane-associated. | PMID: 14702404 PMID: 15028689 PMID: 7473063 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Periplasmic | N/A | yes | yes | No | 26 | 0.179 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n8-19c25/26o | Cytoplasmic | 8 | 35 | ||||||||
| SLYD_ECOLI | P0A9K9 | slyD | b3349 JW3311 | cytoplasmic peripheral IM protein, FKBP-type peptidyl-prolyl cis-trans isomerase SlyD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 31 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||
| FLIJ_ECOLI | P52613 | fliJ flaO flaS | flaO flaS | b1942 JW1926 | cytoplasmic peripheral IM protein, FliJ protein FliJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Part of FlgN-FlgK-FliJ-FlhA complex. | PMID: 22233518 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein; Cytoplasmic side | Cytoplasmic | N/A | no | yes | No | 36 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 89 | |||||||
| AZOR_ECOLI | P41407 | azoR acpD | acpD | b1412 JW1409 | cytoplasmic peripheral IM protein, FMN-dependent NADH-azoreductase AzoR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 19 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-13c18/19o | Cytoplasmic | 9 | 108 | ||||||||
| PFLB_ECOLI | P09373 | pflB pfl | pfl | b0903 JW0886 | cytoplasmic peripheral IM protein, Formate acetyltransferase 1 PflB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 48 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 30 | ||||||
| FDOH_ECOLI | P0AAJ5 | fdoH | b3893 JW3864 | cytoplasmic peripheral IM protein, Formate dehydrogenase-O iron-sulfur subunit FdoH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Part of FDH-O isoenzyme complex whose physiological role is to ensure rapid adaptation during a shift from aerobiosis to anaerobiosis. FDH-O is a membrane-bound enzyme complex composed of three subunits, alpha (FdoG), beta (FdoH), and gamma (FdoI). Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 21890895 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Single-pass membrane protein | Membrane anchored | IM (predicted) | yes | yes | No | 24 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 77 | ||||||||
| HYCE_ECOLI | P16431 | hycE hevE | hevE | b2721 JW2691 | cytoplasmic peripheral IM protein, Formate hydrogenlyase subunit 5 HycE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Nickel-containing large subunit of Hydrogenase 3 (hycABCDEF-GHI) that forms a loose association with the molyb- doenzyme formate dehydrogenase-H on the cytoplasmic face of the cytoplasmic membrane, where together they make up the formate hydrogenlyase complex. | PMID: 1625581 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 27 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 7 | ||||||||
| FCTA_ECOLI | P69902 | frc yfdW | yfdW | b2374 JW2371 | cytoplasmic peripheral IM protein, Formyl-CoA:oxalate CoA-transferase Frc | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Hypothesized to interact with the oxalate/formate antiporter and to oxalyl-CoA decarboxylase to form a large complex. 3D structure formyl-CoA transferase in Oxalobacter formigenes reveals a CoA binding site at the interface of an interlocked dimerPMID: 12839984. | PMID: 12839984 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 24 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | ||||||||
| ALF1_ECOLI | P0A991 | fbaB dhnA | dhnA | b2097 JW5344 | cytoplasmic peripheral IM protein, Fructose-bisphosphate aldolase class 1 FbaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 64 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 4 | |||||||
| ALF_ECOLI | P0AB71 | fbaA fba fda | fba fda | b2925 JW2892 | cytoplasmic peripheral IM protein, Fructose-bisphosphate aldolase class 2 FbaA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. PMID: 2649077 | PMID: 23230279 PMID: 2649077 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | TF | yes | yes | No | 46 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 69 | |||||||
| FUMA_ECOLI | P0AC33 | fumA | b1612 JW1604 | cytoplasmic peripheral IM protein, Fumarate hydratase class I, aerobic FumA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 57 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 37 | |||||||||
| FUMC_ECOLI | P05042 | fumC | b1611 JW1603 | cytoplasmic peripheral IM protein, Fumarate hydratase class II FumC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 57 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 64 | |||||||||
| FRDA_ECOLI | P00363 | frdA | b4154 JW4115 | cytoplasmic peripheral IM protein, Fumarate reductase flavosubunit FrdA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | FrdA and FrdB Fumarate reductase The terminal electron-transfer enzyme fumarate reductase of Escherichia coli is a complex iron-sulfur flavoenzyme composed of four nonidentical subunits organized into two domains: FrdA and -B (a membrane-extrinsic catalytic domain) and FrdC and -D (a transmembrane anchor domain). PMCID: PMC323229 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 23230279 PMCID: PMC323229 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 28 | 0.271 | SpI | 27 | 1.50227 | - | 0 | 0 | Y | n8-18c27/28o | CytoplasmicMembrane | 9 | 50 | |||||||||
| FRDB_ECOLI | P0AC47 | frdB | b4153 JW4114 | cytoplasmic peripheral IM protein, Fumarate reductase iron-sulfur subunit FrdB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | FrdA and FrdB fumarate reductase The terminal electron-transfer enzyme fumarate reductase of Escherichia coli is a complex iron-sulfur flavoenzyme composed of four nonidentical subunits organized into two domains: FrdA and -B (a membrane-extrinsic catalytic domain) and FrdC and -D (a transmembrane anchor domain). PMCID: PMC323229 PMID: 8419359 PMID: 6751816 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 6751816 PMID: 8419359 PMCID: PMC323229 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 28 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 91 | |||||||||
| GATD_ECOLI | P0A9S3 | gatD | b2091 JW2075 | cytoplasmic peripheral IM protein, Galactitol 1-phosphate 5-dehydrogenase GatD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | TF | no | yes | No | 53 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 53 | ||||||||
| MGLA_ECOLI | P0AAG8 | mglA | b2149 JW2136 | cytoplasmic peripheral IM protein, Galactose/methyl galactoside import ATP-binding MglA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 15919657 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 29 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 14 | |||||||||
| PROA_ECOLI | P07004 | proA | b0243 JW0233 | cytoplasmic peripheral IM protein, Gamma-glutamyl phosphate reductase ProA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 48 | 0.168 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 118 | |||||||||
| NAGB_ECOLI | P0A759 | nagB glmD | glmD | b0678 JW0664 | cytoplasmic peripheral IM protein, Glucosamine-6-phosphate deaminase NagB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bridge (219 219) PMID: 8240271 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 32 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 28 | ||||||||
| DCEB_ECOLI | P69910 | gadB | b1493 JW1488 | cytoplasmic peripheral IM protein, Glutamate decarboxylase beta GadB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Localized exclusively in the cytoplasm at neutral pH, but is recruited to the membrane when the pH falls. | PMID: 12912902 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 28 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 14 | ||||||||
| GLTB_ECOLI | P09831 | gltB aspB | aspB | b3212 JW3179 | cytoplasmic peripheral IM protein, Glutamate synthase (NADPH) large chain GltB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 48 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| GSA_ECOLI | P23893 | hemL gsa popC | gsa popC | b0154 JW0150 | cytoplasmic peripheral IM protein, Glutamate-1-semialdehyde 2,1-aminomutase HemL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 26 | 0.222 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 33 | ||||||||
| GLTL_ECOLI | P0AAG3 | gltL | b0652 JW0647 | cytoplasmic peripheral IM protein, Glutamate/aspartate import ATP-binding GltL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 43 | |||||||||||
| GLNQ_ECOLI | P10346 | glnQ | b0809 JW0794 | cytoplasmic peripheral IM protein, Glutamine transport ATP-binding GlnQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 42 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 97 | ||||||||
| GLMS_ECOLI | P17169 | glmS | b3729 JW3707 | cytoplasmic peripheral IM protein, Glutamine--fructose-6-phosphate aminotransferase GlmS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | TF | no | yes | No | 59 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 91 | |||||||
| HEM1_ECOLI | P0A6X1 | hemA | b1210 JW1201 | cytoplasmic peripheral IM protein, Glutamyl-tRNA reductase HemA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 44 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 23 | |||||||||
| GLRX3_ECOLI | P0AC62 | grxC yibM | yibM | b3610 JW3585 | cytoplasmic peripheral IM protein, Glutaredoxin 3 GrxC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bridge (12 15) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 30 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 79 | ||||||||
| GLRX4_ECOLI | P0AC69 | grxD ydhD | ydhD | b1654 JW1646 | cytoplasmic peripheral IM protein, Glutaredoxin 4 GrxD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 15833738 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 42 | 0.264 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 90 | ||||||||
| GSIA_ECOLI | P75796 | gsiA yliA | yliA | b0829 JW5897 | cytoplasmic peripheral IM protein, Glutathione import ATP-binding GsiA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 62 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | ||||||||
| KEFF_ECOLI | P0A754 | kefF yabF | yabF | b0046 JW0045 | cytoplasmic peripheral IM protein, Glutathione-regulated potassium-efflux system ancillary KefF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Properties of four two-component bacterial transport systems of the cation/proton antiporter-2 (CPA2) family led to suggestions that this CPA2 subset may use a channel rather than an antiport mechanism. The transporter subset includes the intensively studied glutathione-gated K+ efflux systems from <i>Escherichia coli</i>, KefGB, and KefFC. KefG and KefF are ancillary proteins. They are peripheral membrane proteins that are encoded in operons with the respective transporter proteins, KefB and KefC, and are required for optimal efflux activity. | PMID: 17679694 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | IM (predicted) | yes | yes | No | 17 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 34 | |||||||
| KEFG_ECOLI | P0A756 | kefG yheR | yheR | b3351 JW3314 | cytoplasmic peripheral IM protein, Glutathione-regulated potassium-efflux system ancillary KefG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Properties of four two-component bacterial transport systems of the cation/proton antiporter-2 (CPA2) family led to suggestions that this CPA2 subset may use a channel rather than an antiport mechanism. The transporter subset includes the intensively studied glutathione-gated K+ efflux systems from Escherichia coli, KefGB, and KefFC. KefG and KefF are ancillary proteins. They are peripheral membrane proteins that are encoded in operons with the respective transporter proteins, KefB and KefC, and are required for optimal efflux activity. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 17679694 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | IM (predicted) | yes | yes | No | 23 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| G3P1_ECOLI | P0A9B2 | gapA | b1779 JW1768 | cytoplasmic peripheral IM protein, Glyceraldehyde-3-phosphate dehydrogenase A GapA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 21 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 73 | |||||||
| GLPK_ECOLI | P0A6F3 | glpK | b3926 JW3897 | cytoplasmic peripheral IM protein, Glycerol kinase GlpK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 22 | 0.143 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 21 | ||||||||
| PLSB_ECOLI | P0A7A7 | plsB | b4041 JW4001 | cytoplasmic peripheral IM protein, Glycerol-3-phosphate acyltransferase PlsB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Phospholipid metabolism complex PlsB-PssA-YbgC-acp Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 16294310 PMID: 23230279 PMID: 4943977 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 27 | 0.194 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | |||||||||
| YEHX_ECOLI | P33360 | yehX | b2129 JW2117 | cytoplasmic peripheral IM protein, Glycine betaine uptake system ATP-binding YehX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 42 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 8 | ||||||||||
| PROV_ECOLI | P14175 | proV | b2677 JW2652 | cytoplasmic peripheral IM protein, Glycine betaine/proline betaine transport system ATP-binding ProV | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 24 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 73 | ||||||||
| GCSP_ECOLI | P33195 | gcvP | b2903 JW2871 | cytoplasmic peripheral IM protein, Glycine dehydrogenase GcvP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 60 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o751-770i | Cytoplasmic | 9 | 21 | ||||||||||
| SYGA_ECOLI | P00960 | glyQ glyS(A) | glyS(A) | b3560 JW3531 | cytoplasmic peripheral IM protein, Glycine--tRNA ligase alpha subunit GlyQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit. Trigger factor-sensitive aggregation. Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | no | yes | No | 57 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 59 | ||||||
| SYGB_ECOLI | P00961 | glyS glyS(B) | glyS(B) | b3559 JW3530 | cytoplasmic peripheral IM protein, Glycine--tRNA ligase beta subunit GlyS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 65 | 0.169 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 77 | |||||||
| GLGA_ECOLI | P0A6U8 | glgA | b3429 JW3392 | cytoplasmic peripheral IM protein, Glycogen synthase GlgA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 32 | 0.162 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 10 | ||||||||||
| GUAA_ECOLI | P04079 | guaA | b2507 JW2491 | cytoplasmic peripheral IM protein, GMP synthase GuaA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 45 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| GNSA_ECOLI | P0AC92 | gnsA yccL | yccL | b4517 JW0976 | cytoplasmic peripheral IM protein, GnsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 50 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||
| GRPE_ECOLI | P09372 | grpE | b2614 JW2594 | cytoplasmic peripheral IM protein, GrpE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Interacts with DmsD is a redox enzyme maturation protein (REMP). PMID: 20153451 | PMID: 20153451 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 35 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| RELA_ECOLI | P0AG20 | relA | b2784 JW2755 | cytoplasmic peripheral IM protein, GTP pyrophosphokinase RelA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 37 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 75 | ||||||||||
| TYPA_ECOLI | P32132 | typA bipA yihK | bipA yihK | b3871 JW5571 | cytoplasmic peripheral IM protein, GTP-binding TypA/BipA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 37 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 88 | |||||||
| ARGK_ECOLI | P27254 | argK ygfD | ygfD | b2918 JW2885 | cytoplasmic peripheral IM protein, GTPase ArgK ArgK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Appears to phosphorylate the periplasmic binding proteins of the lysine, arginine, ornithine transport system as well as the arginine, ornithine transport systemPMID: 2136858. | PMID: 2136858 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 26 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 23 | ||||||||
| HFLX_ECOLI | P25519 | hflX | b4173 JW4131 | cytoplasmic peripheral IM protein, GTPase HflX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | The hflALocus was found to comprise three genes, hflX, hflK, and hflC. HflK and HflC are membrane proteins and form a mem- brane-bound protease complex along with FtsH(HflB), and they are thought to act as modulators of the function of HflB. The role of the HflX GTPase/ATPase is unclear but has been shown to bind to ribosomes. When overexpressed, a portion of HflXProtein appeared in the membrane fraction, while larger amounts fractionated with the cytoplasmic pool (unpublished data cited in PMID: 19181811). In Corynebacterium glutamicum, HflX has been found to occur equally in the cytoplasm and in the membrane fractions (PMID: 15978086). Has no transmembrane region either in E. coli or in C. glutamicum. Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15978086 PMID: 19181811 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 52 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 52 | |||||||
| OBG_ECOLI | P42641 | obgE cgtA obg yhbZ | cgtA obg yhbZ | b3183 JW3150 | cytoplasmic peripheral IM protein, GTPase ObgE/CgtA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; associates 30S, 50S,16S, and 23S rRNA. PMID: 15292126 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15292126 PMID: 21529161 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 25 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 93 | |||||||
| HFLD_ECOLI | P25746 | hflD ycfC | ycfC | b1132 JW5165 | cytoplasmic peripheral IM protein, High frequency lysogenization HflD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Downregulates lambda lysogenization;Interacts with cIIProtein; first gene in purB operon Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11278968 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 54 | 0.157 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 19 | |||||||
| LIVF_ECOLI | P22731 | livF | b3454 JW3419 | cytoplasmic peripheral IM protein, High-affinity branched-chain amino acid transport ATP-binding LivF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 42 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 15 | ||||||||||
| LIVG_ECOLI | P0A9S7 | livG | b3455 JW3420 | cytoplasmic peripheral IM protein, High-affinity branched-chain amino acid transport ATP-binding LivG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 21 | 0.325 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | ||||||||||
| HIS7_ECOLI | P06987 | hisB | b2022 JW2004 | cytoplasmic peripheral IM protein, Histidine biosynthesis bifunctional HisB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 24 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 66 | |||||||
| HISP_ECOLI | P07109 | hisP | b2306 JW2303 | cytoplasmic peripheral IM protein, Histidine transport ATP-binding HisP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 31 | 0.431 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 67 | ||||||||
| SYH_ECOLI | P60906 | hisS | b2514 JW2498 | cytoplasmic peripheral IM protein, Histidine--tRNA ligase HisS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 20 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 59 | |||||||||
| HTRL_ECOLI | P25666 | htrL yibB | yibB | b3618 JW5644 | cytoplasmic peripheral IM protein, HtrL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 45 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 50 | ||||||||
| MBHL_ECOLI | P0ACD8 | hyaB | b0973 JW0955 | cytoplasmic peripheral IM protein, Hydrogenase-1 large chain HyaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Peripherar Inner Membrane Cyto side (Potential) Under anaerobic conditions Escherichia coli synthesizes three membrane-associated [NiFe]-hydrogenases (Hyd). Hyd-1 and Hyd-2 are respiratory hydrogenases with their active sites facing the periplasm. PMID: 22769583 PMID: 2180913 | PMID: 2180913 PMID: 22769583 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Periplasmic (Experimental) | N/A | yes | yes | No | 49 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 9 | ||||||||
| HYFG_ECOLI | P77329 | hyfG | b2487 JW2472 | cytoplasmic peripheral IM protein, Hydrogenase-4 component G HyfG | Phobius predicts a slight hydrophobic area within the body protein | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 27 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||||
| IMDH_ECOLI | P0ADG7 | guaB guaR | guaR | b2508 JW5401 | cytoplasmic peripheral IM protein, Inosine-5'-monophosphate dehydrogenase GuaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Prediction of one very weak transmembrane helix. | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 29 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 49 | ||||||||
| SUHB_ECOLI | P0ADG4 | suhB ssyA | ssyA | b2533 JW2517 | cytoplasmic peripheral IM protein, Inositol-1-monophosphatase SuhB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | SuhB forms a tight complex with RNA polymerase (RNA pol) that inhibits the IMPase catalytic activity of SuhB | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 21 | 0.179 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 86 | ||||||||
| MLAF_ECOLI | P63386 | mlaF yrbF | yrbF | b3195 JW3162 | cytoplasmic peripheral IM protein, Interphospholipid transport system ATP-binding MlaF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Phospholipid ABC transporter-binding protein ATP-binding proteins phospholipid ABC transporter-binding protein ATP-binding protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 64 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 23 | |||||||
| MLAB_ECOLI | P64602 | mlaB yrbB | yrbB | b3191 JW5535 | cytoplasmic peripheral IM protein, Interphospholipid transport system binding MlaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Probable phospholipid ABC transporter-binding protein mlaB Probable phospholipid ABC transporter-binding protein mlaB Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 66 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||
| RSXB_ECOLI | P77223 | rsxB rnfB ydgM | rnfB ydgM | b1628 JW1620 | cytoplasmic peripheral IM protein, Ion-translocating oxidoreductase complex subunit B RsxB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Electron transport. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Periplasmic | N/A | yes | yes | No | 31 | 0.278 | SpI | 30 | 4.42273 | - | 1 | 0 | Y | n3-14c19/20o | CytoplasmicMembrane | 10 | 22 | |||||||
| RSXC_ECOLI | P77611 | rsxC rnfC ydgN | rnfC ydgN | b1629 JW1621 | cytoplasmic peripheral IM protein, Ion-translocating oxidoreductase complex subunit C RsxC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 54 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||
| FHUC_ECOLI | P07821 | fhuC | b0151 JW0147 | cytoplasmic peripheral IM protein, Iron(3+)-hydroxamate import ATP-binding FhuC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1551849 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 39 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 45 | ||||||||
| ISCU_ECOLI | P0ACD4 | iscU nifU yfhN | nifU yfhN | b2529 JW2513 | cytoplasmic peripheral IM protein, Iron-sulfur cluster assembly scaffold IscU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | IscS is critical for iron-sulfur (Fe-S) cluster formation and repair. IscS transfers sulfur to the coregulated "scaffold" protein IscU (NifU), on which Fe-S clusters are assembled. Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 20 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 97 | ||||||||
| ERPA_ECOLI | P0ACC3 | erpA yadR | yadR | b0156 JW0152 | cytoplasmic peripheral IM protein, Iron-sulfur cluster insertion ErpA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 49 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 84 | |||||||||
| YTFE_ECOLI | P69506 | ytfE | b4209 JW4167 | cytoplasmic peripheral IM protein, Iron-sulfur cluster repair YtfE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 21 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 103 | ||||||||
| IDH_ECOLI | P08200 | icd icdA icdE | icdA icdE | b1136 JW1122 | cytoplasmic peripheral IM protein, Isocitrate dehydrogenase (NADP) Icd | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | TF | yes | yes | No | 47 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 96 | |||||||
| ACEA_ECOLI | P0A9G6 | aceA icl | icl | b4015 JW3975 | cytoplasmic peripheral IM protein, Isocitrate lyase AceA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 30 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 42 | ||||||||
| ILVC_ECOLI | P05793 | ilvC | b3774 JW3747 | cytoplasmic peripheral IM protein, Ketol-acid reductoisomerase IlvC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 29 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 97 | |||||||||
| ALKH_ECOLI | P0A955 | eda hga kdgA | hga kdgA | b1850 JW1839 | cytoplasmic peripheral IM protein, KHG/KDPG aldolase Eda | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 30 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 77 | ||||||||
| LHGO_ECOLI | P37339 | lhgO ygaF | ygaF | b2660 JW2635 | cytoplasmic peripheral IM protein, L-2-hydroxyglutarate oxidase LhgO | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted), Soluble IM Fraction | yes | yes | No | 21 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | ||||||||
| YECC_ECOLI | P37774 | yecC | b1917 JW1902 | cytoplasmic peripheral IM protein, L-cystine transport system ATP-binding YecC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 34 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 37 | |||||||||||
| LLDD_ECOLI | P33232 | lldD lctD | lctD | b3605 JW3580 | cytoplasmic peripheral IM protein, L-lactate dehydrogenase LldD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | LldD is a cytochrome. There is a strong experimental indication that it is a membrane bound protein although no transmembrane helix is predicted PMID: 18473. PMID: 8407843 PMID: 6997721 PMID: 18473 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 18473 PMID: 23230279 PMID: 6997721 PMID: 8407843 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Membrane associated (Experimental) | IM (predicted-detected) | yes | yes | No | 32 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 4 | |||||||
| SDHL_ECOLI | P16095 | sdaA | b1814 JW1803 | cytoplasmic peripheral IM protein, L-serine dehydratase 1 SdaA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 20 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 71 | ||||||||||
| TDCB_ECOLI | P0AGF6 | tdcB | b3117 JW3088 | cytoplasmic peripheral IM protein, L-threonine dehydratase catabolic TdcB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential substrate of periplasmic chaperone YfgM. PMID: 25403562 Putative substrate for the periplasmic chaperone YfgM. PMID: 25403562 | PMID: 25403562 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | YfgM | yes | yes | No | 23 | 0.152 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 72 | ||||||||
| LACI_ECOLI | P03023 | lacI | b0345 JW0336 | cytoplasmic peripheral IM protein, Lactose operon repressor LacI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Regulates lac operon transcription when in homotetrameric form. | PMID: 15863616 PMID: 21936772 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 33 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 32 | |||||||||
| LPXB_ECOLI | P10441 | lpxB pgsB | pgsB | b0182 JW0177 | cytoplasmic peripheral IM protein, Lipid-A-disaccharide synthase LpxB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | It has been demonstrate by mass spectrometry and autoradiography that 1.6 to 3.5 phospholipid molecules co-purify with each LpxB monomerPMID: 19883124. It has been demonstrate by mass spectrometry and autoradiography that 1.6 to 3.5 phospholipid molecules co-purify with each LpxB monomer. PMID: 19883124 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19883124 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 23 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 47 | ||||||||
| LCFA_ECOLI | P69451 | fadD oldD | oldD | b1805 JW1794 | cytoplasmic peripheral IM protein, Long-chain-fatty-acid--CoA ligase FadD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Acyl-coenzyme A (CoA) synthetase that may interact with the inner membrane. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | yes | yes | No | 63 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 36 | |||||||
| PLDB_ECOLI | P07000 | pldB | b3825 JW5584 | cytoplasmic peripheral IM protein, Lysophospholipase L2 PldB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Gene and characteristics of deduced amino acid sequence of lysophospholipase L2. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 34 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 36 | ||||||||
| MDH_ECOLI | P61889 | mdh | b3236 JW3205 | cytoplasmic peripheral IM protein, Malate dehydrogenase Mdh | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. PMID: 7028159 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15976458 PMID: 23230279 PMID: 7028159 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | N/A | TF | yes | yes | No | 18 | 0.251 | SpI | 17 | 0.386899 | - | 0 | 0 | Y | n3-12c17/18o | Unknown | 6 | |||||||||
| MQO_ECOLI | P33940 | mqo yojH | yojH | b2210 JW2198 | cytoplasmic peripheral IM protein, Malate:quinone oxidoreductase Mqo | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | High signal PProbability and lipoP SPIPrediction; weak TmHMMPrediction definite membrane association according to literature. MQOIs a flavin adenine dinucleotide (FAD)- and lipid-dependent peripheral membrane protein catalyzing the oxidation ofL-malate to oxaloacetate. PMID: 11092847 PMID: 368072 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11092847 PMID: 23230279 PMID: 368072 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Membrane associated (Experimental) | IM (predicted) | yes | yes | Yes | 27 | 0.278 | SpI | 21 | 8.41159 | - | 0 | 0 | Y | n4-15c21/22o | Unknown | 6 | 17 | ||||||||
| MALK_ECOLI | P68187 | malK | b4035 JW3995 | cytoplasmic peripheral IM protein, Maltose/maltodextrin import ATP-binding MalK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | ATPase of maltose uptake system. MalF functions in maltose transport as a 1:1:2 complex with the integral inner membrane protein MalG and the peripheral inner membrane protein MalK Crystal structure of a catalytic intermediate of the maltose transporter. PMID: 18033289 | PMID: 16079137 PMID: 18456666 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 15 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 19 | ||||||||
| PTMA_ECOLI | P69824 | cmtB | b2934 JW2901 | cytoplasmic peripheral IM protein, Mannitol-specific cryptic phosphotransferase enzyme IIA component CmtB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 9525892 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 19 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 96 | |||||||||
| FADK_ECOLI | P38135 | fadK ydiD | ydiD | b1701 JW5910 | cytoplasmic peripheral IM protein, Medium-chain fatty-acid--CoA ligase FadK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homologous to FadD13 protein of Mycobacterium that is peripheral | PMID: 22560731 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | N/A | no | yes | No | 37 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| MAP1_ECOLI | P0AE18 | map | b0168 JW0163 | cytoplasmic peripheral IM protein, Methionine aminopeptidase Map | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Has been viewed through fluorescence microscopy and located evenly throughout cytoplasm. Small scale study of labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. PMID: 17272300 | PMID: 17272300 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 22 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 63 | |||||||||
| METN_ECOLI | P30750 | metN abc | abc | b0199 JW0195 | cytoplasmic peripheral IM protein, Methionine import ATP-binding MetN | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 42 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 23 | |||||||
| METH_ECOLI | P13009 | metH | b4019 JW3979 | cytoplasmic peripheral IM protein, Methionine synthase MetH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 35 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||||
| SYM_ECOLI | P00959 | metG | b2114 JW2101 | cytoplasmic peripheral IM protein, Methionine--tRNA ligase MetG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit. Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 20 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 49 | |||||||
| MOAB_ECOLI | P0AEZ9 | moaB chlA2 | chlA2 | b0782 JW0765 | cytoplasmic peripheral IM protein, Molybdenum cofactor biosynthesis B MoaB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 24 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 105 | ||||||||
| MODC_ECOLI | P09833 | modC chlD narD | chlD narD | b0765 JW0748 | cytoplasmic peripheral IM protein, Molybdenum import ATP-binding ModC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 35 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | |||||||||||
| MTFA_ECOLI | P76346 | mtfA yeeI | yeeI | b1976 JW1958 | cytoplasmic peripheral IM protein, MtfA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Cytoplasmic transciption factor that shuttles from chromosome to the membranes as a peripheral protein on the PtsG transporter. Specifically it binds to the unphosphorylated, trnasport-mediating form of the EIIBCGlc subunit. PMID: 16855233 | PMID: 15063852 PMID: 16855233 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 36 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 87 | |||||||
| PTFX1_ECOLI | P77439 | fryA ypdD | ypdD | b2383 JW2380 | cytoplasmic peripheral IM protein, Multiphosphoryl transfer 1 FryA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Multiphosphoryl transfer protein 1 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 17 | 0.156 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n2-10c16/17o | Cytoplasmic | 9 | 38 | ||||||||
| PTFX2_ECOLI | P32670 | ptsA frwA yijH | frwA yijH | b3947 JW5555 | cytoplasmic peripheral IM protein, Multiphosphoryl transfer 2 PtsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Multiphosphoryl transfer protein 2 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 18 | 0.56 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 68 | ||||||||
| PTFAH_ECOLI | P69811 | fruB fpr fruF | fpr fruF | b2169 JW2156 | cytoplasmic peripheral IM protein, Multiphosphoryl transfer FruB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 8013873 PMID: 2841594 | PMID: 15911532 PMID: 2841594 PMID: 8013873 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 39 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 91 | |||||||
| MTOX_ECOLI | P40874 | solA | b1059 JW1046 | cytoplasmic peripheral IM protein, N-methyl-L-tryptophan oxidase SolA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 16 | 0.149 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 73 | ||||||||||
| NADK_ECOLI | P0A7B3 | nadK yfjB yfjE | yfjB yfjE | b2615 JW2596 | cytoplasmic peripheral IM protein, NAD kinase NadK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Fluorescent fusions of ppnK have been monitored via fluorescence microscopy. ppnK distributed irregularly throughout the cytoplasm, with some clusters formed. | PMID: 17272300 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 20 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 32 | |||||||
| DHNA_ECOLI | P00393 | ndh | b1109 JW1095 | cytoplasmic peripheral IM protein, NADH dehydrogenase Ndh | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Contains amphipathic C-terminal anchor (390-406). Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 20933494 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | IM (predicted) | yes | yes | No | 22 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 35 | ||||||||
| NUOB_ECOLI | P0AFC7 | nuoB | b2287 JW5875 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit B NuoB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Crystal structure of the entire respiratory complex I PMID: 23417064 Crystal structure of the entire respiratory complex I PMID: 21822288 PMID: 7607227 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15037611 PMID: 19189973 PMID: 21822288 PMID: 23230279 PMID: 23417064 PMID: 7607227 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side | Cytoplasmic (Experimental) | IM (predicted) | yes | yes | No | 62 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 78 | ||||||||
| NUOCD_ECOLI | P33599 | nuoC nuoCD nuoD | nuoCD nuoD | b2286 JW5375 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit C/D NuoC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 PMID: 7607227 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 16079137 PMID: 23230279 PMID: 7607227 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | IM (predicted) | TF | yes | yes | No | 39 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 17 | ||||||
| NUOE_ECOLI | P0AFD1 | nuoE | b2285 JW2280 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit E NuoE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | NADH dehydrogenase I is composed of 13 different subunits. Subunits nuoCD, E, F, and G constitute the peripheral sector of the complexPMID: 19737520. Thermus homologue: Q56221 (NQO2_THET8). Copurifies with trigger factor in pull down assaysPMID: 19737520. PMID: 11416161 PMID: 7607227 PMID: 7690854 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11416161 PMID: 23230279 PMID: 23543743 PMID: 7607227 PMID: 7690854 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 67 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | ||||||||
| NUOF_ECOLI | P31979 | nuoF | b2284 JW2279 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit F NuoF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | NADH dehydrogenase I is composed of 13 different subunits. Subunits nuoCD, E, F, and G constitute the peripheral sector of the complex.cThermus homologue: Q56222 (NQO1_THET8) Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 57 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | |||||||||
| NUOG_ECOLI | P33602 | nuoG | b2283 JW2278 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit G NuoG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. PMID: 11416161 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11416161 PMID: 15919657 PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 57 | 0.143 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 17 | |||||||
| NUOI_ECOLI | P0AFD6 | nuoI | b2281 JW2276 | cytoplasmic peripheral IM protein, NADH-quinone oxidoreductase subunit I NuoI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 11416161 PMID: 15037611 PMID: 19189973 PMID: 21822288 PMID: 23230279 PMID: 23417064 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.17 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o6-26i | Cytoplasmic | 9 | 72 | |||||||||
| MAO2_ECOLI | P76558 | maeB ypfF | ypfF | b2463 JW2447 | cytoplasmic peripheral IM protein, NADP-dependent malic enzyme MaeB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 45 | 0.165 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | |||||||
| SEQA_ECOLI | P0AFY8 | seqA | b0687 JW0674 | cytoplasmic peripheral IM protein, Negative modulator of initiation of replication SeqA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Membrane-associated oriC-binding machinery of E. coli is a multiprotein complex that includes the SeqA and SeqB proteins. PMID: 9660922 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 9660922 PMID: 9736699 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 43 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 13 | |||||||
| NADE_ECOLI | P18843 | nadE efg ntrL | efg ntrL | b1740 JW1729 | cytoplasmic peripheral IM protein, NH(3)-dependent NAD(+) synthetase NadE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 20 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| NIKD_ECOLI | P33593 | nikD | b3479 JW3444 | cytoplasmic peripheral IM protein, Nickel import ATP-binding NikD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 48 | 0.168 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 45 | |||||||||||
| NIKE_ECOLI | P33594 | nikE | b3480 JW3445 | cytoplasmic peripheral IM protein, Nickel import ATP-binding NikE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 68 | 0.149 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 41 | |||||||||||
| GLNK_ECOLI | P0AC55 | glnK ybaI | ybaI | b0450 JW0440 | cytoplasmic peripheral IM protein, Nitrogen regulatory P-II 2 GlnK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Encodes a member of the PII signal transduction protein family, proteins that regulate enzyme activity and gene expression in response to the intracellular nitrogen status; cytoplasmic transciption factor that binds maltotriose and ATP and shuttles between the chromosome and membranes as a peripheral protein on the the ammonium transporter AmtB. | PMID: 10231487 PMID: 11847102 PMID: 14668330 PMID: 9720863 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 67 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 41 | ||||||||
| PTSN_ECOLI | P69829 | ptsN rpoP yhbI | rpoP yhbI | b3204 JW3171 | cytoplasmic peripheral IM protein, Nitrogen regulatory PtsN | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | enzyme IIA(Ntr) of the nitrogen PTS regulates the intracellular concentration of K(+) by direct interaction with TrkA and KdpD. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 17289841 PMID: 21605551 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 26 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 82 | |||||||
| NDK_ECOLI | P0A763 | ndk | b2518 JW2502 | cytoplasmic peripheral IM protein, Nucleoside diphosphate kinase Ndk | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Nucleoside diphosphate kinase (EC 2.7.4.6) (Ndk) is a ubiquitous enzyme functioning in the intracellular distribution of terminal phosphate bond energy among the various nucleotides used in synthetic and regulatory functions in cellsPMID: 8606147. Based on studies in Pseudomonas and many other systems including mitochondria, the uracil-processing DNA repair nuclease ndk is known to interact to plasma membranes and mitochondrial inner membranePMID: 15096615. Binding is regulated by nucleotidesPMID: 19146889. In Pseudomonas, an intracellular protease cleaves the 16-kDa form of Ndk to a 12-kDa form that undergoes autophosphorylation with an efficiency almost identical to that of the 16-kDa form. The 12-kDa form is predominantly associated with the cell membrane fraction, whereas the 16-kDa form is predominantly cytoplasmic. In the membrane-associated state, the 12-kDa form of Ndk was found to synthesize GTP in preference to other nucleoside triphosphates. The formation of the 12-kDa form of Ndk and its association with the cell membrane were found to be related to the growth stage of <i>P.aeruginosa</i>, with less than 1% of the 12-kDa Ndk detectable in the membrane fraction at early log phase in comparison with the levels present at late stationary phasePMID: 8606147. Cytosolic Ndks bind directly to membrane lipids in a dynamic process and can be fully reconstituted with phospholipids and recombinant Ndk PMID: 19146889. Ndks may act as a reservoir of high energy phosphate, supporting the operation of membrane-based processes that utilize nucleotides other than ATP, such as intracellular traffic and phospholipid biosynthesis. Trigger factor-sensitive aggregationPMID: 19737520. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19146889 PMID: 23230279 PMID: 8606147 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | no | yes | No | 17 | 0.158 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 64 | |||||||
| OPDA_ECOLI | P27298 | prlC opdA | opdA | b3498 JW3465 | cytoplasmic peripheral IM protein, Oligopeptidase A PrlC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 26 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 94 | |||||||||
| OPPD_ECOLI | P76027 | oppD | b1246 JW1238 | cytoplasmic peripheral IM protein, Oligopeptide transport ATP-binding OppD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Oligopeptide permease (Opp) transporters are located in the plasma membrane and have functions generally related to the uptake of peptides from the extracellular environment. OppD is the ATP-binding protein. PMID: 24793159 Based on sequence similarity, OppB and OppC are the membrane components of the ABC transporter, and OppD and OppF are the ATP-binding components of the ABC transporter PMID: 1738314 Opp-LacZ hybrid proteins were used to show that OppB, OppC and OppD are membrane-associated proteins. PMID: 2821267 PMID: 16045610 [22087229 ] PMID: 3926486 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16045610 PMID: 1738314 PMID: 22087229 PMID: 23230279 PMID: 24793159 PMID: 2821267 PMID: 3926486 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 69 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 18 | ||||||||
| OPPF_ECOLI | P77737 | oppF | b1247 JW1239 | cytoplasmic peripheral IM protein, Oligopeptide transport ATP-binding OppF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 70 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 17 | ||||||||
| ORN_ECOLI | P0A784 | orn o204a yjeR | o204a yjeR | b4162 JW5740 | cytoplasmic peripheral IM protein, Oligoribonuclease Orn | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 24438330 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 48 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 103 | |||||||
| BETA_ECOLI | P17444 | betA | b0311 JW0303 | cytoplasmic peripheral IM protein, Oxygen-dependent choline dehydrogenase BetA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Exhibites aberrant localization by microscopy in the absence of YidC. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 3512525 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | no | yes | No | 19 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 8 | ||||||||
| NFSB_ECOLI | P38489 | nfsB dprA nfnB nfsI ntr | dprA nfnB nfsI ntr | b0578 JW0567 | cytoplasmic peripheral IM protein, Oxygen-insensitive NAD(P)H nitroreductase NfsB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 12788749 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | IM (predicted) | yes | yes | No | 18 | 0.166 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 86 | |||||||||
| PCNB_ECOLI | P0ABF1 | pcnB | b0143 JW5808 | cytoplasmic peripheral IM protein, PcnB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | RNA degradosome component/adds polyA tails to mRNAs targeted for degradation. The pcnB gene product, is the main enzyme responsible for RNA polyadenylation in E. coli. Polyadenylated RNA molecules are rapidly degraded by a multiprotein complex called RNA degradosome. PAP I localizes in the cytosol but also, like the RNA degradosome, in cellular membranes. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15737627 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 26 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 23 | ||||||||
| DHAM_ECOLI | P37349 | dhaM ycgC | ycgC | b1198 JW5185 | cytoplasmic peripheral IM protein, PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Part of Dihydroxyacetone kinase complex ([DhaM]2[DhaK]2[DhaL]). DhaMIs homologous to certain components of PTS: to a domain of EI, to HPr, and to the AB domains of EII. Part of Dihydroxyacetone kinase complex ([DhaM]2[DhaK]2[DhaL]). DhaMIs homologous to certain components of PTS: to a domain of EI, to HPr, and to the AB domains of EII. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 36 | 0.134 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 74 | ||||||||
| DEF_ECOLI | P0A6K3 | def fms | fms | b3287 JW3248 | cytoplasmic peripheral IM protein, Peptide deformylase Def | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 42 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 66 | |||||||||
| PPIB_ECOLI | P23869 | ppiB | b0525 JW0514 | cytoplasmic peripheral IM protein, Peptidyl-prolyl cis-trans isomerase B PpiB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 PMID: 9268657 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | yes | yes | No | 10 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 64 | |||||||||
| PSPA_ECOLI | P0AFM6 | pspA | b1304 JW1297 | cytoplasmic peripheral IM protein, Phage shock A PspA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Forms large oligomers and binds directly to phospholipids (preferentially phosphatidylserine and phosphatidylglycerol). PMC3709507 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19555453 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | Prophage Transposase | yes | no | No | 23 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 113 | |||||||
| PSPD_ECOLI | P0AFV8 | pspD | b1307 JW1300 | cytoplasmic peripheral IM protein, Phage shock D PspD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12562786 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | Prophage Transposase | no | no | No | 64 | 0.182 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 34 | |||||||
| SYFA_ECOLI | P08312 | pheS | b1714 JW5277 | cytoplasmic peripheral IM protein, Phenylalanine--tRNA ligase alpha subunit PheS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 19 | 0.166 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 12 | |||||||||
| SYFB_ECOLI | P07395 | pheT | b1713 JW1703 | cytoplasmic peripheral IM protein, Phenylalanine--tRNA ligase beta subunit PheT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 29 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 79 | |||||||||
| PHOL_ECOLI | P0A9K3 | ybeZ | b0660 JW0657 | cytoplasmic peripheral IM protein, PhoH-like protein YbeZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 68 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 61 | |||||||
| CHEZ_ECOLI | P0A9H9 | cheZ | b1881 JW1870 | cytoplasmic peripheral IM protein, phosphatase CheZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. PMID: 12644507 | PMID: 12644507 PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 66 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 107 | ||||||||
| PLSX_ECOLI | P27247 | plsX | b1090 JW5156 | cytoplasmic peripheral IM protein, Phosphate acyltransferase PlsX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 24 | 0.213 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||||
| PSTB_ECOLI | P0AAH0 | pstB phoT | phoT | b3725 JW3703 | cytoplasmic peripheral IM protein, Phosphate import ATP-binding PstB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified as peripheral membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 3881386 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 41 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 23 | |||||||
| PHOU_ECOLI | P0A9K7 | phoU nmpA | nmpA | b3724 JW3702 | cytoplasmic peripheral IM protein, Phosphate-specific transport system accessory PhoU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Identified as peripheral membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 PMID: 3536855 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 17 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 94 | |||||||
| PSD_ECOLI | P0A8K1 | psd | b4160 JW4121 | cytoplasmic peripheral IM protein, Phosphatidylserine decarboxylase proenzyme Psd | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Phosphatidylserine decarboxylase is composed of two nonidentical subunits, alpha and beta, derived from a single proenzyme. The proenzyme is processed in a post-translational event into the heterodimer. This enzyme is unique among the known pyruvoyl-dependent decarboxylases because it is membrane-associated. PMID: 3042771 The phosphatidylserine decarboxylase (EC 4.1.1.65, phosphatidyl-L-serine carboxy-lyase) of Escherichia coli is associated with the cytoplasmic membrane and requires nonionic detergent for solubilization and detection of enzymatic activity PMID: 1495415 A strain of Escherichia coli bearing a hybrid plasmid containing the psd gene, starved for isoleucine by the addition of valine, produces amounts of phosphatidyl-serine decarboxylase, a membrane-bound enzyme, about 40-fold higher than wild type. PMID: 368058 The first phospholipid biosynthetic enzyme to be purified to homogeneity was Psd of E. coli. Beginning in the late 1960s purification of membrane proteins after solubilization with detergents was an increasingly popular endeavor. PMID: 22925633 PMID: 3042771 PMID: 5543671 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1495415 PMID: 23230279 PMID: 3042771 PMID: 368058 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 23 | 0.185 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 32 | ||||||||
| CYSH_ECOLI | P17854 | cysH | b2762 JW2732 | cytoplasmic peripheral IM protein, Phosphoadenosine phosphosulfate reductase CysH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 59 | 0.168 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 11 | |||||||||
| PTHP_ECOLI | P0AA04 | ptsH hpr | hpr | b2415 JW2408 | cytoplasmic peripheral IM protein, Phosphocarrier HPr PtsH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 22 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 88 | ||||||||
| CAPP_ECOLI | P00864 | ppc glu | glu | b3956 JW3928 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate carboxylase Ppc | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 48 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||||
| PPSA_ECOLI | P23538 | ppsA pps | pps | b1702 JW1692 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate synthase PpsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | One very weak transmembrane region predicted. Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 56 | 0.169 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 48 | |||||||
| PT1P_ECOLI | P37177 | ptsP ygdF ygdO | ygdF ygdO | b2829 JW2797 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate-dependent phosphotransferase system PtsP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Phosphoenolpyruvate-protein phosphotransferase ptsP Localization to the inner surface of the cytoplasmic membrane by immunoelectron microscopy of enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system of Escherichia coli. PMID: 2644649 | PMID: 2644649 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.185 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | |||||||
| PT1_ECOLI | P08839 | ptsI | b2416 JW2409 | cytoplasmic peripheral IM protein, Phosphoenolpyruvate-phosphotransferase PtsI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 23230279 PMID: 2644649 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 15 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 90 | |||||||||
| PGK_ECOLI | P0A799 | pgk | b2926 JW2893 | cytoplasmic peripheral IM protein, Phosphoglycerate kinase Pgk | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 21 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 100 | |||||||||
| SIXA_ECOLI | P76502 | sixA yfcW | yfcW | b2340 JW2337 | cytoplasmic peripheral IM protein, Phosphohistidine phosphatase SixA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His-Asp phosphorelayPMID: 9489669. The structure of SixA reveals it forms a relatively shallow groove important for accommodating the kidney-shaped four-helix bundle of the HPt domain of AcrBPMID: 17628145. | PMID: 10734219 PMID: 17628145 PMID: 9489669 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 57 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 79 | ||||||||
| PHNC_ECOLI | P16677 | phnC | b4106 JW4067 | cytoplasmic peripheral IM protein, Phosphonates import ATP-binding PhnC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 23 | 0.137 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 10 | |||||||||||
| DEOB_ECOLI | P0A6K6 | deoB drm thyR | drm thyR | b4383 JW4346 | cytoplasmic peripheral IM protein, Phosphopentomutase DeoB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 40 | 0.147 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 101 | ||||||||
| PHNP_ECOLI | P16692 | phnP | b4092 JW4053 | cytoplasmic peripheral IM protein, Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase PhnP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 8335257 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Periplasmic (Experimental) | N/A | yes | yes | No | 21 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-10c15/16o | Cytoplasmic | 9 | |||||||||||
| PUR7_ECOLI | P0A7D7 | purC | b2476 JW2461 | cytoplasmic peripheral IM protein, Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 65 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 50 | |||||||||
| PPK1_ECOLI | P0A7B1 | ppk | b2501 JW2486 | cytoplasmic peripheral IM protein, Polyphosphate kinase Ppk | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1331061 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane | Cytoplasmic | N/A | yes | yes | No | 26 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 7 | ||||||||
| PNP_ECOLI | P05055 | pnp | b3164 JW5851 | cytoplasmic peripheral IM protein, Polyribonucleotide nucleotidyltransferase Pnp | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Polynucleotide phosphorylase (PNPase) or Polyribonucleotide nucleotidyltransferase Is a cytoplasmic enzyme that has also been isolated in association with the inner membrane (Stenberg et al., 2005; Maddalo et al., 2011). It is not known if association is direct. The protein has weak hydrophobic patches and three regions with weak predictions from Phobius for membrane interaction. Membrane association may be via binding to RNAaseE with which PNPase interacts as part of the multienzyme complex known as the RNA degradosome. RNAseE has been shown to bind to membranes (Khemici et al., 2008). The interaction of RNase E with PNPase , brings together two enzymes important in the degradation of mRNA. Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 16079137 PMID: 23230279 PMID: 24438330 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 30 | 0.323 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 74 | |||||||
| WAAU_ECOLI | P27242 | waaU rfaK waaK | rfaK waaK | b3623 JW3598 | cytoplasmic peripheral IM protein, polysaccharide 1,2-N-acetylglucosaminetransferase WaaU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 1657881 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Membrane; Peripheral membrane protein | Cytoplasmic | N/A | no | yes | No | 33 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||
| RFAG_ECOLI | P25740 | rfaG pcsA waaG | pcsA waaG | b3631 JW3606 | cytoplasmic peripheral IM protein, polysaccharide core biosynthesis RfaG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 25 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 30 | ||||||||
| RFAP_ECOLI | P25741 | rfaP waaP | waaP | b3630 JW3605 | cytoplasmic peripheral IM protein, polysaccharide core heptose RfaP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.155 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 33 | |||||||||
| RFAQ_ECOLI | P25742 | rfaQ waaQ | waaQ | b3632 JW3607 | cytoplasmic peripheral IM protein, polysaccharide core heptosyltransferase RfaQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 25 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 33 | |||||||||
| LPTB_ECOLI | P0A9V1 | lptB yhbG | yhbG | b3201 JW3168 | cytoplasmic peripheral IM protein, polysaccharide export system ATP-binding LptB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 16079137 PMID: 17056748 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic(experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 43 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 19 | ||||||||
| RFAC_ECOLI | P24173 | rfaC rfa-2 waaC yibC | rfa-2 waaC yibC | b3621 JW3596 | cytoplasmic peripheral IM protein, polysaccharide heptosyltransferase 1 RfaC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 50 | 0.195 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 51 | |||||||||
| YGAU_ECOLI | P0ADE6 | ygaU yzzM | yzzM | b2665 JW2640 | cytoplasmic peripheral IM protein, Potassium binding Kbp YgaU | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Contains Peptidoglycan-binding LysM and phospholipid binding Bon domain but no signal peptide. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 Contains Peptidoglycan-binding LysM and phospholipid binding Bon domain but no signal peptide. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 The OsmY protein is an Escherichia coli 20 kDa outer membrane or periplasmic protein that is expressed in response to a variety of stress conditions, in particular, helping to provide protection against osmotic shock. One hypothesis is that OsmY prevents shrinkage of the cytoplasmic compartment by contacting the phospholipid interfaces surrounding the periplasmic space. The domain architecture of two BON domains alone suggests that these domains contact the surfaces of phospholipids, with each domain contacting a membrane PMID: 12175925. Homologous to OsmY. | PMID: 12878000 PMID: 21541338 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 10 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 89 | ||||||||
| KDPF_ECOLI | P36937 | kdpF | b4513 JW0687 | cytoplasmic peripheral IM protein, Potassium-transporting ATPase KdpF subunit KdpF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | KdpF, could be identified on high resolution SDS-polyacrylamide gels in addition to the subunits KdpA, KdpB, and KdpC. Furthermore, it could be demonstrated that KdpF remains associated with the purified complex. As determined by mass spectrometry, this pe PMID: 9789555 | PMID: 21890895 PMID: 9789555 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Membrane Anchored (Experimental) | IM (predicted) | no | yes | No | 23 | 0.109 | CYT | 0 | -0.200913 | - | 1 | 0 | Y | n5-16c22/23o | CytoplasmicMembrane | 10 | 29 | ||||||||
| ARND_ECOLI | P76472 | arnD pmrJ yfbH | pmrJ yfbH | b2256 JW2250 | cytoplasmic peripheral IM protein, Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 67 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 10 | |||||||||
| SUFC_ECOLI | P77499 | sufC ynhD | ynhD | b1682 JW1672 | cytoplasmic peripheral IM protein, Probable ATP-dependent transporter SufC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | SufE protein and the SufBCD complex stimulate the sulfurylase activity of SufS. Probably through direct interaction. Homolog to import ATP-binding protein MalK. PMID: 12554644 | PMID: 12554644 PMID: 12941942 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 32 | 0.213 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 69 | |||||||
| DDPD_ECOLI | P77268 | ddpD yddP | yddP | b1484 JW1479 | cytoplasmic peripheral IM protein, Probable D,D-dipeptide transport ATP-binding DdpD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 25 | 0.176 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 23 | ||||||||||
| DDPF_ECOLI | P77622 | ddpF yddO | yddO | b1483 JW1478 | cytoplasmic peripheral IM protein, Probable D,D-dipeptide transport ATP-binding DdpF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 32 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 18 | ||||||||||
| FETP_ECOLI | P0A8P3 | yggX | b2962 JW2929 | cytoplasmic peripheral IM protein, Probable Fe(2+)-trafficking protein YggX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally verified gene-product. Methionine start codon is cleaved. Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 41 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-11c16/17o | Unknown | 2 | 107 | |||||||||
| ENGB_ECOLI | P0A6P7 | engB yihA | yihA | b3865 JW5930 | cytoplasmic peripheral IM protein, Probable GTP-binding EngB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Fluorescent fusions of YqiK have been monitored via fluorescence microscopy. YqiK was found to be distributed diffusely throughout cytoplasm. | PMID: 17272300 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 43 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||
| FETA_ECOLI | P77279 | fetA ybbL | ybbL | b0490 JW0479 | cytoplasmic peripheral IM protein, Probable iron export ATP-binding FetA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 33 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 42 | ||||||||
| YCJR_ECOLI | P76044 | ycjR | b1314 JW5202 | cytoplasmic peripheral IM protein, Probable ketose 3-epimerase YcjR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 47 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 44 | |||||||||
| YBHF_ECOLI | P0A9U1 | ybhF | b0794 JW5104 | cytoplasmic peripheral IM protein, Probable multidrug ABC transporter ATP-binding YbhF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 38 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 42 | ||||||||||
| SYP_ECOLI | P16659 | proS drpA | drpA | b0194 JW0190 | cytoplasmic peripheral IM protein, Proline--tRNA ligase ProS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 19 | 0.254 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 16 | ||||||
| PRPE_ECOLI | P77495 | prpE yahU | yahU | b0335 JW0326 | cytoplasmic peripheral IM protein, Propionate--CoA ligase PrpE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to FadD13 protein of Mycobacterium that is peripheralPMID: 22560731. | PMID: 22560731 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 44 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 13 | ||||||||
| SECB_ECOLI | P0AG86 | secB | b3609 JW3584 | cytoplasmic peripheral IM protein, Protein-export SecB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Cytoplasmic protein that forms transient interactions with the membrane; binds to the C-terminus of SecA. Protein that acts as its membrane receptor. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 2170023 PMID: 23230279 PMID: 9767586 PMCID: PMC1326294 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 53 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 88 | ||||||||
| HEMG_ECOLI | P0ACB4 | hemG yihB | yihB | b3850 JW3827 | cytoplasmic peripheral IM protein, Protoporphyrinogen IX dehydrogenase HemG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 33 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 75 | |||||||||
| PTFLA_ECOLI | P32155 | frvA yiiK | yiiK | b3900 JW3871 | cytoplasmic peripheral IM protein, PTS system fructose-like EIIA component FrvA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Fructose-like phosphotransferase enzyme IIA component | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 19 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 68 | ||||||||
| PTFB2_ECOLI | P69816 | frwB yijK | yijK | b3950 JW3922 | cytoplasmic peripheral IM protein, PTS system fructose-like EIIB component 2 FrwB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | The sgaTBA genes of Escherichia coli encode a putative 12-transmembrane alpha-helical segment (12 TMS) transporter, an enzyme IIB-like protein and an enzyme IIA-like protein of the phosphotransferase system (PTS), respectively. SgaT represents a novel prototypical enzyme IIC that functions with SgaA and SgaB to allow phosphoryl transfer from HPr(his-P) to l-ascorbate via the phosphoryl transfer pathway | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 21 | 0.363 | SpI | 20 | 4.62655 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 87 | ||||||||
| PTFB3_ECOLI | P32676 | frwD yijN | yijN | b3953 JW3925 | cytoplasmic peripheral IM protein, PTS system fructose-like EIIB component 3 FrwD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Sequence analysis indicates that an frwD encoded protein has similarity to the IIB domains of the PTS Enzymes II specific for fructose. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 21 | 0.559 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-12c17/18o | Unknown | 6 | 43 | ||||||||
| PTKA_ECOLI | P69828 | gatA | b2094 JW2078/JW2081 | cytoplasmic peripheral IM protein, PTS system galactitol-specific EIIA component GatA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Part of phosphoenolpyruvate-dependent carbohydrate transport system (PTS). The carbohydrate-specific permease, is constituted of two cytoplasmic domains, IIA and IIB, and a transmembrane channel IIC domain. GatA (IIA domain) interacts with GatB (IIB domain) PMID: 16963640 . Copurifies with trigger factor in pull down assays PMID: 19737520. | PMID: 16963640 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | no | yes | No | 69 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 71 | |||||||
| PTKB_ECOLI | P37188 | gatB | b2093 JW2077 | cytoplasmic peripheral IM protein, PTS system galactitol-specific EIIB component GatB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Part of galactitol PTS permease complex. Strong Signal Peptide prediction. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Disulfide bond-containing protein PMID: 25664544 | PMID: 16963640 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | Yes | 20 | 0.743 | SpI | 19 | 8.62134 | - | 0 | 0 | Y | n5-14c19/20o | Cytoplasmic | 10 | |||||||||
| PTHA_ECOLI | P05706 | srlB gutB | gutB | b2704 JW2673 | cytoplasmic peripheral IM protein, PTS system glucitol/sorbitol-specific EIIA component SrlB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | PTS system glucitol/sorbitol-specific EIIA component.The hydropathic profile of the Enzyme IIgut revealed 7 or 8 long hydrophobic segments which may traverse the cell membrane as alpha-helices as well as 2 or 4 short strongly hydrophobic stretches which may traverse the membrane as beta-structure PMID: 3553176. | PMID: 2824435 PMID: 3553176 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 35 | 0.143 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 115 | |||||||
| PTGA_ECOLI | P69783 | crr gsr iex tgs treD | gsr iex tgs treD | b2417 JW2410 | cytoplasmic peripheral IM protein, PTS system glucose-specific EIIA component Crr | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12717030 PMID: 23230279 PMID: 2960675 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | N/A | yes | yes | No | 44 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 113 | |||||||
| PTNAB_ECOLI | P69797 | manX gptB ptsL | gptB ptsL | b1817 JW1806 | cytoplasmic peripheral IM protein, PTS system mannose-specific EIIAB component ManX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component. Identified by native-PAGE technique for the study of membrane protein complexes in the inner and outer membranes of Escherichia coli. The mannose phosphotransferase system transporter (EIIman) is composed of three subunits, ManX (IIABman), ManY (IICman), and ManZ (IIDman), which are reported to assemble in a 2:1:2 stoichiometry. The IIC and IID components are integral inner membrane proteins. Identified in the inner membrane by biochemical fractionation followed by two-dimensional gel electrophoresis and tandem mass spectrometry. PMID: 15911532 PMID: 10094700 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10094700 PMID: 15911532 PMID: 15919657 PMID: 16079137 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 43 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 93 | |||||||
| PTQA_ECOLI | P69791 | chbA celC | celC | b1736 JW1725 | cytoplasmic peripheral IM protein, PTS system N,N'-diacetylchitobiose-specific EIIA component ChbA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | IIA component of the phosphoenolpyruvate (glycose transferase PTS system) which is a prototypic signaling system responsible for the vectorial uptake and phosphorylation of carbohydrate substrates. Unlike most PTS systems, phosphoenolpyruvate is composed of two soluble proteins, IIA and IIB, and one transmembrane receptor IIC. | PMID: 10913122 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | pseudogene (Ochman & Davalos, 2006) | yes | yes | No | 38 | 0.187 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 111 | ||||||
| PTQB_ECOLI | P69795 | chbB celA | celA | b1738 JW1727 | cytoplasmic peripheral IM protein, PTS system N,N'-diacetylchitobiose-specific EIIB component ChbB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | IIB component of the phosphoenolpyruvate (glycose transferase PTS system) which is a prototypic signaling system responsible for the vectorial uptake and phosphorylation of carbohydrate substrates. Unlike most PTS systems, phosphoenolpyruvate is composed of two soluble proteins, IIA and IIB, and one transmembrane receptor IIC. PMID: 2092358 | PMID: 10913122 PMID: 2092358 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Membrane associated (Experimental) | N/A | yes | yes | No | 28 | 0.176 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n8-19c27/28o | Cytoplasmic | 10 | 97 | |||||||
| HINT_ECOLI | P0ACE7 | hinT ycfF | ycfF | b1103 JW1089 | cytoplasmic peripheral IM protein, Purine nucleoside phosphoramidase HinT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 57 | 0.182 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 84 | |||||||||
| DEOD_ECOLI | P0ABP8 | deoD pup | pup | b4384 JW4347 | cytoplasmic peripheral IM protein, Purine nucleoside phosphorylase DeoD-type DeoD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 27 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 108 | |||||||||
| YCJV_ECOLI | P77481 | ycjV ymjB | ymjB | b4524 JW1311/JW5203 b1318 | cytoplasmic peripheral IM protein, Putative ABC transporter ATP-binding YcjV | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | pseudogene (Uniprot) | yes | no | No | 37 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 10 | ||||||||
| WBBK_ECOLI | P37751 | wbbK yefI | yefI | b2032 JW2017 | cytoplasmic peripheral IM protein, Putative glycosyltransferase WbbK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 21 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 32 | |||||||
| SGRT_ECOLI | C1P5Z7 | sgrT | b4662 JW0068.1 | cytoplasmic peripheral IM protein, Putative inhibitor of glucose uptake transporter SgrT | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Putative inhibitor of glucose uptake transporter sgrT. SgrT protein expresssion is inducted by ??-methylglucoside. | PMID: 18042713 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | - | N/A | no | yes | No | 23 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||
| YIDD_ECOLI | P0A8C8 | yidD | b4557 JW3682 | cytoplasmic peripheral IM protein, Putative insertion efficiency factor YidD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 21803992 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | no | yes | No | 42 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||
| LONH_ECOLI | P75867 | ycbZ | b0955 JW0938 | cytoplasmic peripheral IM protein, Putative Lon protease homolog YcbZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 24 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||||
| YRAR_ECOLI | P45469 | yraR | b3152 JW5528 | cytoplasmic peripheral IM protein, Putative NAD(P)-binding YraR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 32 | 0.195 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 12 | |||||||||
| PHNK_ECOLI | P16678 | phnK | b4097 JW5727 | cytoplasmic peripheral IM protein, Putative phosphonates utilization ATP-binding PhnK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Homolog to import ATP-binding protein MalK. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 23 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 6 | ||||||||||
| YADI_ECOLI | P36881 | yadI | b0129 JW0125 | cytoplasmic peripheral IM protein, Putative phosphotransferase enzyme IIA component YadI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Putative phosphotransferase enzyme IIA component yadI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 46 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 17 | |||||||||
| SGCB_ECOLI | P58035 | sgcB | b4565 JW5967 | cytoplasmic peripheral IM protein, Putative phosphotransferase enzyme IIB component SgcB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Part of SgcABC complex, a putative PTSPermease. SgcA (Enzyme IIASgc)Is homologous to the IIA domains of the fructose - and mannitol-specific PTSPermeases (fruB and cmtB) which are peripherally accossiated proteins. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 19 | 0.218 | SpI | 21 | 4.43024 | - | 0 | 0 | Y | n4-11c19/20o | Cytoplasmic | 9 | ||||||||||
| WBBJ_ECOLI | P37750 | wbbJ yefH | yefH | b2033 JW2018 | cytoplasmic peripheral IM protein, Putative polysaccharide biosynthesis O-acetyl transferase WbbJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 24 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| GSPE_ECOLI | P45759 | gspE yheG | yheG | b3326 JW3288 | cytoplasmic peripheral IM protein, Putative type II secretion system E GspE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | ATPase of the Type II secretion system (cryptic in K12) EspL (GspL homolog) protein interacts through its N-terminal cytoplasmic domain with EspL (GspL homolog) protein | PMID: 16525507 PMID: 17255937 PMCID: PMC398259 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 23 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 21 | |||||||
| YEEL_ECOLI | P76349 | yeeL | b4497 b1979/b1980 | cytoplasmic peripheral IM protein, Putative YeeL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | pseudogene (Uniprot), pseudogene (Ochman & Davalos, 2006) | no | no | No | 19 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 13 | ||||||||
| SAPD_ECOLI | P0AAH4 | sapD trkE | trkE | b1291 JW1284 | cytoplasmic peripheral IM protein, Putrescine export system ATP-binding SapD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 53 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 22 | |||||||
| SAPF_ECOLI | P0AAH8 | sapF | b1290 JW1283 | cytoplasmic peripheral IM protein, Putrescine export system ATP-binding SapF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 45 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 8 | ||||||||
| POTG_ECOLI | P31134 | potG | b0855 JW5818 | cytoplasmic peripheral IM protein, Putrescine transport ATP-binding PotG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 35 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 11 | |||||||||||
| PDXH_ECOLI | P0AFI7 | pdxH | b1638 JW1630 | cytoplasmic peripheral IM protein, Pyridoxine/pyridoxamine 5'-phosphate oxidase PdxH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 43 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 51 | ||||||||
| ODP1_ECOLI | P0AFG8 | aceE | b0114 JW0110 | cytoplasmic peripheral IM protein, Pyruvate dehydrogenase E1 component AceE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | AceE is the E1 subunit of the 10MDa Escherichia coli pyruvate dehydrogenase multienzyme complex, which catalyzes the oxidative decarboxylation of the central metabolite pyruvate to CO(2) and acetate (crystal structure solved as a dimer PMID: 11955070). The E1 subunit is present as a 24mer within the complex. AceE is also part of a very large complex partially resolved by cryoEM PMID: 16338405. Analogous enzyme pyryvate oxidase-PoxB is membrane associated PMID: 18988747. Trigger factor-sensitive aggregation. Outer membrane protein determined by LC-MS (Gevaert et al 2002) Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 18988747 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | TF | yes | yes | No | 53 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | ||||||||
| POXB_ECOLI | P07003 | poxB | b0871 JW0855 | cytoplasmic peripheral IM protein, Pyruvate dehydrogenase PoxB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Is one of several membrane-associated form of the enzyme has a tendency to self-aggregate,is flavo protein dehydrogenases that feed electrons in to the high lysurfacelabile,and manifests. Pyruvate oxidase is a membrane-associated flavoprotein dehydrogenase which is greatly activated by lipids and detergents. The carboxyl-terminal region of the protein has been shown to play a critical role in the interaction with lipids. | PMID: 2663858 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 62 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 20 | ||||||||
| KPYK1_ECOLI | P0AD61 | pykF | b1676 JW1666 | cytoplasmic peripheral IM protein, Pyruvate kinase I PykF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 42 | 0.167 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 108 | ||||||||||
| KPYK2_ECOLI | P21599 | pykA | b1854 JW1843 | cytoplasmic peripheral IM protein, Pyruvate kinase II PykA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 43 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 43 | ||||||||||
| DLD_ECOLI | P06149 | dld | b2133 JW2121 | cytoplasmic peripheral IM protein, Quinone-dependent D-lactate dehydrogenase Dld | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Requires phospholipid for maximal activity. Exhibites aberrant localization by microscopy in the absence of YidC. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 33 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 78 | ||||||||
| RECA_ECOLI | P0A7G6 | recA lexB recH rnmB tif umuB zab | lexB recH rnmB tif umuB zab | b2699 JW2669 | cytoplasmic peripheral IM protein, RecA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Protein of Escherichia coli binds specifically to acidic phospholipids such as cardiolipin and phosphatidylglycerol.The interaction of RecA protein with cardiolipin and phosphatidylglycerol, which represent two of the three major phospholipids of the E. coli membrane, may be physiologically important, as it provides a possible mechanism for the RecA-membrane association during the SOS response. Trigger factor-sensitive aggregation. Disulfide bond-containing protein PMID: 25664544 | PMID: 2228969 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | no | yes | No | 3 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 88 | ||||||
| NARG_ECOLI | P09152 | narG bisD narC | bisD narC | b1224 JW1215 | cytoplasmic peripheral IM protein, Respiratory nitrate reductase 1 alpha chain NarG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Part of the nitrate reductase A (NarGHI) of Escherichia coli which is membrane anchored through the NarI subunit. NarH is the electron transfer subunit. PMID: 12910261 In vivo associations of Escherichia coli NarJ with a peptide of the first 50 residues of nitrate reductase catalytic subunit NarG. PMID: 19295650 When E. coli is grown anaerobically in the presence of high levels of nitrate, the respiratory chain that is formed is terminated by NarGHI otherwise known as the quinol nitrate oxidoreductase. PMID: 2674654 The heterotrimeric NarGHI has an ?????? structure encoded by narGHI respectively. The ?? and ?? subunits can be purified as a soluble NarGH dimer in the cytoplasm showing that these 2 subunits associate to form a stable subcomplex before association with the membrane ?? subunit. PMID: 3371362 The NarGH subcomplex is anchored to the cytoplasmic side of the membrane by NarI. NarJ interacts with apoNarGH early on, promoting the insertion of the [4Fe???S] clusters and molybdenum in a sequential manner. Insertion of the [Fe???S] clusters in NarH are not dependent on NarJ. Binding of NarJ also prevents premature targeting of the NarGH dimer to the membrane. PMID: 16286471 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12910261 PMID: 16286471 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 29 | |||||||
| NARH_ECOLI | P11349 | narH | b1225 JW1216 | cytoplasmic peripheral IM protein, Respiratory nitrate reductase 1 beta chain NarH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Part of the nitrate reductase A (NarGHI) of Escherichia coli which is membrane anchored through the NarI subunit. NarH is the electron transfer subunit. PMID: 12910261 In vivo associations of Escherichia coli NarJ with a peptide of the first 50 residues of nitrate reductase catalytic subunit NarG. PMID: 19295650 When E. coli is grown anaerobically in the presence of high levels of nitrate, the respiratory chain that is formed is terminated by NarGHI otherwise known as the quinol nitrate oxidoreductase. PMID: 2674654 The heterotrimeric NarGHI has an ?????? structure encoded by narGHI respectively. The ?? and ?? subunits can be purified as a soluble NarGH dimer in the cytoplasm showing that these 2 subunits associate to form a stable subcomplex before association with the membrane ?? subunit. PMID: 3371362 The NarGH subcomplex is anchored to the cytoplasmic side of the membrane by NarI. NarJ interacts with apoNarGH early on, promoting the insertion of the [4Fe???S] clusters and molybdenum in a sequential manner. Insertion of the [Fe???S] clusters in NarH are not dependent on NarJ. Binding of NarJ also prevents premature targeting of the NarGH dimer to the membrane. PMID: 16286471 The NarGH subcomplex is anchored to the cytoplasmic side of the membrane by NarI. NarJ interacts with apoNarGH early on, promoting the insertion of the [4Fe???S] clusters and molybdenum in a sequential manner. Insertion of the [Fe???S] clusters in NarH are not dependent on NarJ. Binding of NarJ also prevents premature targeting of the NarGH dimer to the membrane. PMID: 16286471 PMID: 3053688 PMID: 2233673 PMID: 2674654 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12910261 PMID: 2233673 PMID: 23230279 PMID: 3053688 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 32 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 13 | ||||||||
| NARZ_ECOLI | P19319 | narZ | b1468 JW1463 | cytoplasmic peripheral IM protein, Respiratory nitrate reductase 2 alpha chain NarZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | |||||||||
| NARY_ECOLI | P19318 | narY | b1467 JW1462 | cytoplasmic peripheral IM protein, Respiratory nitrate reductase 2 beta chain NarY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 32 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 14 | ||||||||
| WBBL_ECOLI | P36667 | wbbL | b4571 JW2016 b2031 | cytoplasmic peripheral IM protein, Rhamnosyltransferase WbbL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 51 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 54 | |||||||||
| RHSB_ECOLI | P16917 | rhsB | b3482 JW5679 | cytoplasmic peripheral IM protein, RhsB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | Rhs Element | no | no | No | 46 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Extracellular | 9 | ||||||||||
| RNE_ECOLI | P21513 | rne ams hmp1 | ams hmp1 | b1084 JW1071 | cytoplasmic peripheral IM protein, Ribonuclease E Rne | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Membrane-binding specificity of NRne was confirmed using circular dichroism difference spectroscopy. RnE binds specifically to anionic phospholipids through electrostatic interactions through N-terminal region (NRne, residues 1-499). Identified DsbC substrate PMID: 19953543 Identified DsbA substrate PMID: 19953543 PMID: 2011493 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 Part of membrane-associating assemblies that coil around the periphery of the cell when visualized by immunofluorescence microscopy. These assemblies co-localize with the RNA degradosome and participate in the RNA degradation process. PMID: 24438330 | PMID: 15911532 PMID: 18976283 PMID: 2011493 PMID: 22509045 PMID: 23230279 PMID: 24438330 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 62 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||
| RNR_ECOLI | P21499 | rnr vacB yjeC | vacB yjeC | b4179 JW5741 | cytoplasmic peripheral IM protein, Ribonuclease R Rnr | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 3 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 45 | ||||||||
| RIR1_ECOLI | P00452 | nrdA dnaF | dnaF | b2234 JW2228 | cytoplasmic peripheral IM protein, Ribonucleoside-diphosphate reductase 1 subunit alpha NrdA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Disulfide bridges between 225 and 462 PMID: 9395490 Disulfide bridges between 225 and 462 PMID: 9395490 Disulfide bridges between 225 and 462 PMID: 9395490 | PMID: 23230279 PMID: 9395490 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 40 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 63 | |||||||
| RBSA_ECOLI | P04983 | rbsA | b3749 JW3728 | cytoplasmic peripheral IM protein, Ribose import ATP-binding RbsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 35 | 0.548 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 49 | |||||||||||
| KPRS_ECOLI | P0A717 | prs prsA | prsA | b1207 JW1198 | cytoplasmic peripheral IM protein, Ribose-phosphate pyrophosphokinase Prs | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 31 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 9 | ||||||
| RLUB_ECOLI | P37765 | rluB yciL | yciL | b1269 JW1261 | cytoplasmic peripheral IM protein, Ribosomal large subunit pseudouridine synthase B RluB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 32 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| RLME_ECOLI | P0C0R7 | rlmE ftsJ mrsF rrmJ | ftsJ mrsF rrmJ | b3179 JW3146 | cytoplasmic peripheral IM protein, Ribosomal RNA large subunit methyltransferase E RlmE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 21529161 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 29 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 16 | |||||||
| RLMI_ECOLI | P75876 | rlmI yccW | yccW | b0967 JW5898 | cytoplasmic peripheral IM protein, Ribosomal RNA large subunit methyltransferase I RlmI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 29 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| RSMA_ECOLI | P06992 | rsmA ksgA | ksgA | b0051 JW0050 | cytoplasmic peripheral IM protein, Ribosomal RNA small subunit methyltransferase A RsmA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; Overex<x>pression of RsmA suppresses defects in mutant of era. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 21529161 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||
| RSMC_ECOLI | P39406 | rsmC yjjT | yjjT | b4371 JW4333 | cytoplasmic peripheral IM protein, Ribosomal RNA small subunit methyltransferase C RsmC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Ribosom related | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 27 | 0.158 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 43 | |||||||
| RSME_ECOLI | P0AGL7 | rsmE yggJ | yggJ | b2946 JW2913 | cytoplasmic peripheral IM protein, Ribosomal RNA small subunit methyltransferase E RsmE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Ribosomal | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 40 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 18 | |||||||
| RSMH_ECOLI | P60390 | rsmH mraW yabC | mraW yabC | b0082 JW0080 | cytoplasmic peripheral IM protein, Ribosomal RNA small subunit methyltransferase H RsmH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. PMID: 10572301 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10572301 PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 54 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 65 | |||||||
| RIMJ_ECOLI | P0A948 | rimJ | b1066 JW1053 | cytoplasmic peripheral IM protein, Ribosomal-protein-alanine acetyltransferase RimJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Assembly cofactor of ribosome; associate with the Pre-30S subunit. Overex<x>pression of RimJ suppresses defects in S5(G28D) mutations. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | |||||||||
| RIMP_ECOLI | P0A8A8 | rimP yhbC | yhbC | b3170 JW5533 | cytoplasmic peripheral IM protein, Ribosome maturation factor RimP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm ( Experimental) | Assembly cofactor of ribosome; associate with the 30S subunit. | PMID: 21529161 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 19 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 111 | |||||||
| YFIA_ECOLI | P0AD49 | raiA yfiA | yfiA | b2597 JW2578 | cytoplasmic peripheral IM protein, Ribosome-associated inhibitor A RaiA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 63 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 98 | ||||||||
| RRF_ECOLI | P0A805 | frr rrf | rrf | b0172 JW0167 | cytoplasmic peripheral IM protein, Ribosome-recycling factor Frr | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 109 | ||||||||
| PROQ_ECOLI | P45577 | proQ yebJ yobE yoeC | yebJ yobE yoeC | b1831 JW5300 | cytoplasmic peripheral IM protein, RNA chaperone | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 27 | 0.162 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 69 | ||||||||
| RAPZ_ECOLI | P0A894 | rapZ yhbJ | yhbJ | b3205 JW3172 | cytoplasmic peripheral IM protein, RNase adapter RapZ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 18 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 7 | 38 | |||||||||
| FRMA_ECOLI | P25437 | frmA adhC | adhC | b0356 JW0347 | cytoplasmic peripheral IM protein, S-(hydroxymethyl)glutathione dehydrogenase FrmA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 50 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 71 | ||||||||
| METK_ECOLI | P0A817 | metK metX | metX | b2942 JW2909 | cytoplasmic peripheral IM protein, S-adenosylmethionine synthase MetK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Fluorescent fusions of MetK have been monitored via fluorescence microscopy. Cells containing almost exclusively diffuse cytoplasmic MetK, or focused locations. | PMID: 17272300 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 64 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 47 | |||||||
| LUXS_ECOLI | P45578 | luxS ygaG | ygaG | b2687 JW2662 | cytoplasmic peripheral IM protein, S-ribosylhomocysteine lyase LuxS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | no | yes | No | 19 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 110 | |||||||
| MIND_ECOLI | P0AEZ3 | minD | b1175 JW1164 | cytoplasmic peripheral IM protein, Septum site-determining MinD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | MinD recruits MinC to the membrane to form the MinC-MinD complex, which inhibits septum formation, and MinE acts to localize and restrict inhibition to the inappropriate septation sites. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10096083 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 25 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 95 | ||||||||
| GLYA_ECOLI | P0A825 | glyA | b2551 JW2535 | cytoplasmic peripheral IM protein, Serine hydroxymethyltransferase | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 47 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||
| SYS_ECOLI | P0A8L1 | serS | b0893 JW0876 | cytoplasmic peripheral IM protein, Serine--tRNA ligase SerS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 67 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 28 | ||||||||
| SRP54_ECOLI | P0AGD7 | ffh | b2610 JW5414 | cytoplasmic peripheral IM protein, Signal recognition particle Ffh | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 18281057 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 63 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 5 | 106 | |||||||
| FTSY_ECOLI | P10121 | ftsY | b3464 JW3429 | cytoplasmic peripheral IM protein, Signal recognition particle receptor FtsY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Contains an essential and autonomous membrane-binding amphipathic helix. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11353766 PMID: 17726013 PMID: 18281057 PMID: 19414018 PMID: 21543314 PMID: 23230279 PMID: 8194520 PMID: 9177162 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 3 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | |||||||||
| UGPC_ECOLI | P10907 | ugpC | b3450 JW3415 | cytoplasmic peripheral IM protein, sn-glycerol-3-phosphate import ATP-binding UgpC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 37 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 20 | ||||||||
| STHA_ECOLI | P27306 | sthA sth udhA | sth udhA | b3962 JW5551 | cytoplasmic peripheral IM protein, Soluble pyridine nucleotide transhydrogenase SthA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | SthA is bound on the inner mebrane through PntAB heterodimer. Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 14660605 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 22 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 22 | ||||||
| POTA_ECOLI | P69874 | potA | b1126 JW1112 | cytoplasmic peripheral IM protein, Spermidine/putrescine import ATP-binding PotA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 11976340 PMID: 1939142 PMID: 23230279 PMID: 7592703 PMID: 8366082 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 22 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 93 | ||||||||
| SRA_ECOLI | P68191 | sra rpsV | rpsV | b1480 JW5962 | cytoplasmic peripheral IM protein, Stationary-phase-induced ribosome-associated Sra | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Small protein identified experimentallyPMID: 19121005. Stationary-phase-induced and ribosome-associated proteinPMID: 11292794. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry)PMID: 23230279. | PMID: 11292794 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 26 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||
| SSPB_ECOLI | P0AFZ3 | sspB | b3228 JW3197 | cytoplasmic peripheral IM protein, Stringent starvation B SspB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 47 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||||
| SDHA_ECOLI | P0AC41 | sdhA | b0723 JW0713 | cytoplasmic peripheral IM protein, Succinate dehydrogenase flavosubunit SdhA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 PMID: 9600841 PMID: 9740056 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12560550 PMID: 16079137 PMID: 23230279 PMID: 9600841 PMID: 9740056 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | TF | yes | yes | No | 50 | 0.189 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 10 | |||||||
| SDHB_ECOLI | P07014 | sdhB | b0724 JW0714 | cytoplasmic peripheral IM protein, Succinate dehydrogenase iron-sulfur subunit SdhB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Identified in nucleoids collected by sucrose gradient centrifugation and analyzed by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). PMID: 21541338 PMID: 6388571 PMID: 2987185 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 16079137 PMID: 23230279 PMID: 2987185 PMID: 6388571 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic (Experimental) | IM (predicted) | yes | yes | No | 28 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 34 | ||||||||
| SUCD_ECOLI | P0AGE9 | sucD | b0729 JW0718 | cytoplasmic peripheral IM protein, Succinate--CoA ligase (ADP-forming) subunit alpha SucD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 31 | 0.171 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 70 | ||||||||
| SUCC_ECOLI | P0A836 | sucC | b0728 JW0717 | cytoplasmic peripheral IM protein, Succinate--CoA ligase SucC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 32 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 67 | ||||||||
| GABD_ECOLI | P25526 | gabD | b2661 JW2636 | cytoplasmic peripheral IM protein, Succinate-semialdehyde dehydrogenase GabD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 28 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 60 | ||||||||||
| SUFA_ECOLI | P77667 | sufA ydiC | ydiC | b1684 JW1674 | cytoplasmic peripheral IM protein, SufA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | PMID: 19366265 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | no | No | 34 | 0.137 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 85 | |||||||||
| CYSA_ECOLI | P16676 | cysA | b2422 JW2415 | cytoplasmic peripheral IM protein, Sulfate/thiosulfate import ATP-binding CysA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 33 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 14 | ||||||||
| SYDP_ECOLI | P0A8U0 | syd ydr | ydr | b2793 JW2764 | cytoplasmic peripheral IM protein, Syd | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side | Cytoplasmic | N/A | yes | yes | No | 20 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 59 | |||||||
| DMSD_ECOLI | P69853 | dmsD ynfI | ynfI | b1591 JW5262 | cytoplasmic peripheral IM protein, Tat proofreading chaperone DmsD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Chaperone for TAT signal peptides The ynfEFGHI operon is a paralogue of the Escherichia coli dmsABC operon. ynfE and ynfF are paralogues of dmsA. ynfG and ynfH are paralogues of dmsB and dmsC, respectively. PMID: 14522592 DmsD is a redox enzyme maturation protein (REMP) which interacts with the twin-arginine leader sequence of DmsA, the catalytic subunit of DMSO reductase. It interacts with several general chaperones (DnaK, DnaJ, GrpE, GroEL, Tig and Ef-Tu) via in vitro protein-protein interaction screening approaches. It was also found to interact with proteins involved in the molybdenum cofactor biosynthesis pathway. PMID: 20153451 | PMID: 12813051 PMID: 19652330 PMID: 20153451 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 31 | 0.453 | SpI | 30 | 2.43679 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | ||||||||
| TAUB_ECOLI | Q47538 | tauB ssiB yaiQ | ssiB yaiQ | b0366 JW0358 | cytoplasmic peripheral IM protein, Taurine import ATP-binding TauB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 57 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 10 | ||||||||||
| WECF_ECOLI | P56258 | wecF rffT yifM | rffT yifM | b4481 JW5596 | cytoplasmic peripheral IM protein, TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase WecF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | in/in | Cell inner membrane | Cytoplasmic | IM (predicted) | pseudogene (Ochman & Davalos, 2006) | yes | yes | No | 29 | 0.203 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 48 | |||||
| THIQ_ECOLI | P31548 | thiQ yabJ | yabJ | b0066 JW0065 | cytoplasmic peripheral IM protein, Thiamine import ATP-binding ThiQ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Two very weak TM predictions; membrane associated activity known. Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system PMID: 12175925 | PMID: 12175925 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 25 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 8 | |||||||
| THIK_ECOLI | P75948 | thiK ycfN | ycfN | b1106 JW1092 | cytoplasmic peripheral IM protein, Thiamine kinase ThiK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 39 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 9 | |||||||||||
| TPX_ECOLI | P0A862 | tpx yzzJ | yzzJ | b1324 JW1317 | cytoplasmic peripheral IM protein, Thiol peroxidase Tpx | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Binds to TrxA. although initially reported to be a periplasmic enzyme, the formation of a mixed-disulfide complex with TrxA indicates a cytoplasmic localization. PMID: 7499381 PMID: 9298646 Disulfide bond-containing protein PMID: 25664544 | PMID: 23230279 PMID: 7499381 PMID: 9298646 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Periplasm | Periplasmic (Experimental) | N/A | yes | yes | No | 33 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Periplasmic | 10 | ||||||||
| THIO_ECOLI | P0AA25 | trxA fipA tsnC | fipA tsnC | b3781 JW5856 | cytoplasmic peripheral IM protein, Thioredoxin 1 TrxA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. Disulfide bridge (33 36) PMID: 10489448 Disulfide bond-containing protein PMID: 25664544 | PMID: 10489448 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | no | yes | No | 20 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 89 | |||||||
| SYT_ECOLI | P0A8M3 | thrS | b1719 JW1709 | cytoplasmic peripheral IM protein, Threonine--tRNA ligase ThrS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 33 | 0.154 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 22 | |||||||
| TYPH_ECOLI | P07650 | deoA tpp ttg | tpp ttg | b4382 JW4345 | cytoplasmic peripheral IM protein, Thymidine phosphorylase DeoA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | no | yes | No | 53 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 12 | |||||||||
| TALB_ECOLI | P0A870 | talB yaaK | yaaK | b0008 JW0007 | cytoplasmic peripheral IM protein, Transaldolase B TalB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 33 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 84 | ||||||
| RHO_ECOLI | P0AG30 | rho nitA psuA rnsC sbaA tsu | nitA psuA rnsC sbaA tsu | b3783 JW3756 | cytoplasmic peripheral IM protein, Transcription termination factor Rho | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 44 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||
| NUSG_ECOLI | P0AFG0 | nusG | b3982 JW3945 | cytoplasmic peripheral IM protein, Transcription termination/antitermination NusG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 26 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 72 | ||||||||||
| TKT1_ECOLI | P27302 | tktA tkt | tkt | b2935 JW5478 | cytoplasmic peripheral IM protein, Transketolase 1 TktA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | yes | yes | No | 25 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 32 | |||||||
| TKT2_ECOLI | P33570 | tktB | b2465 JW2449 | cytoplasmic peripheral IM protein, Transketolase 2 TktB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 24 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | ||||||||||
| SECA_ECOLI | P10408 | secA azi pea prlD | azi pea prlD | b0098 JW0096 | cytoplasmic peripheral IM protein, translocase subunit SecA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 70 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 58 | |||||||
| INSH5_ECOLI | P76071 | insH5 | b1370 JW1363 | cytoplasmic peripheral IM protein, Transposase InsH for insertion sequence element IS5Y | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | Insertion Sequence, Transposase, pseudogene (Uniprot) | no | no | No | 49 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||
| TREC_ECOLI | P28904 | treC olgH | olgH | b4239 JW4198 | cytoplasmic peripheral IM protein, Trehalose-6-phosphate hydrolase TreC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Trigger factor-sensitive aggregation. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 60 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 9 | ||||||
| OTSA_ECOLI | P31677 | otsA | b1896 JW5312 | cytoplasmic peripheral IM protein, Trehalose-6-phosphate synthase OtsA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 19 | 0.248 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 30 | |||||||||
| TIG_ECOLI | P0A850 | tig | b0436 JW0426 | cytoplasmic peripheral IM protein, Trigger factor Tig | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit PMID: 8633085 Interacts with DmsD is a redox enzyme maturation protein (REMP). PMID: 20153451 | PMID: 20153451 PMID: 23230279 PMID: 8633085 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 21 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 87 | ||||||||
| TPIS_ECOLI | P0A858 | tpiA tpi | tpi | b3919 JW3890 | cytoplasmic peripheral IM protein, Triosephosphate isomerase TpiA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 40 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 96 | ||||||||
| TRKA_ECOLI | P0AGI8 | trkA | b3290 JW3251 | cytoplasmic peripheral IM protein, Trk system potassium uptake TrkA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | PMID: 23230279 PMID: 2674131 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | no | yes | No | 17 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-11c16/17o | CytoplasmicMembrane | 10 | 68 | |||||||||
| TRMJ_ECOLI | P0AE01 | trmJ yfhQ | yfhQ | b2532 JW2516 | cytoplasmic peripheral IM protein, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 63 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 78 | ||||||||
| MNME_ECOLI | P25522 | mnmE thdF trmE | thdF trmE | b3706 JW3684 | cytoplasmic peripheral IM protein, tRNA modification GTPase MnmE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | A GTPase that exhibits high intrinsic GTPase hydrolysis rate,Low affinity for GTP, and extremely low affinity for GDP Can form self-assemblies. Is a cytoplasmic protein partially associated with the inner membrane. Involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs. Essential for viability depending on genetic background. Fluorescent fusions of MnmE have been monitored via fluorescence microscopy. MnmE located predominantly beside the membrane. | PMID: 10601028 PMID: 17272300 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 47 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 89 | |||||||
| MNMG_ECOLI | P0A6U3 | mnmG gidA trmF | gidA trmF | b3741 JW3719 | cytoplasmic peripheral IM protein, tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Similar localization to mnmE; may form a complex together | PMID: 17062623 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 25 | 0.172 | CYT | 0 | -0.200913 | - | 0 | 1 | N | o601-619i | Cytoplasmic | 9 | 6 | |||||||
| DUSA_ECOLI | P32695 | dusA yjbN | yjbN | b4049 JW5950 | cytoplasmic peripheral IM protein, tRNA-dihydrouridine(20/20a) synthase DusA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||
| YFIF_ECOLI | P0AGJ5 | yfiF | b2581 JW2565 | cytoplasmic peripheral IM protein, tRNA/rRNA methyltransferase YfiF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Copurifies with trigger factor in pull down assays. | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | TF | no | yes | No | 45 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | ||||||||
| SYY_ECOLI | P0AGJ9 | tyrS | b1637 JW1629 | cytoplasmic peripheral IM protein, Tyrosine--tRNA ligase TyrS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Translation unit | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 65 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 63 | ||||||||
| LPXH_ECOLI | P43341 | lpxH ybbF | ybbF | b0524 JW0513 | cytoplasmic peripheral IM protein, UDP-2,3-diacylglucosamine hydrolase LpxH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Phobius weak prediction of a hydrophobic TMIn the middle of sequence/Kyte-Doolittle predicts several hydrophobic patches | PMID: 20608695 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 33 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 20 | |||||||
| WECG_ECOLI | P27836 | wecG rffM | rffM | b3794 JW3770 | cytoplasmic peripheral IM protein, UDP-N-acetyl-D-mannosaminuronic acid transferase WecG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 27 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 35 | |||||||||
| MURG_ECOLI | P17443 | murG | b0090 JW0088 | cytoplasmic peripheral IM protein, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase MurG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Pyrophosphoryl-undecaprenol N-acetylglucosamine transferase. Murein synthesis peripheral membrane protein interacting with cardiolipin. PMID: 8449890 PMID: 10892798 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 10892798 PMID: 23230279 PMID: 8449890 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Membrane associated (Experimental) | N/A | yes | yes | No | 27 | 0.156 | TMH | 0 | 3.61924 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 48 | ||||||||
| MURC_ECOLI | P17952 | murC | b0091 JW0089 | cytoplasmic peripheral IM protein, UDP-N-acetylmuramate--L-alanine ligase MurC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Trigger factor-sensitive aggregation. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble IM Fraction + | TF | yes | yes | No | 41 | 0.228 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 76 | |||||||
| USPA_ECOLI | P0AED0 | uspA | b3495 JW3462 | cytoplasmic peripheral IM protein, Universal stress A UspA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | The Usp superfamily encompasses an ancient and conserved group of proteins that are found in bacteria, archaea,fungi, flies and plants. Usually each organism has several copies of Usp genes. Escherichia coli contains six Usp proteins, which can be divided into two subfamilies on the basis of sequence similarity. PMID: 19101563 Three of these proteins belong to the UspA subfamily (UspA, UspC, and UspD), and two to the UspFG subfamily (UspF and UspG). Another homologue is YbdQ. UspC binds to the membrane-integrated sensor kinase KdpD involved in K+ ion sensing. The same could be true for the other Usp proteins but we could not find direct evidence in the literature. PMID: 1453957 PMID: 8506346 PMID: 8740179 PMID: 9405142 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 1453957 PMID: 15911532 PMID: 19101563 PMID: 23230279 PMID: 8506346 PMID: 8740179 PMID: 9405142 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 33 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 80 | ||||||||
| USPD_ECOLI | P0AAB8 | uspD yiiT | yiiT | b3923 JW3894 | cytoplasmic peripheral IM protein, Universal stress D UspD | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 54 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 96 | |||||||
| USPG_ECOLI | P39177 | uspG ybdQ yzzU | ybdQ yzzU | b0607 JW0600 | cytoplasmic peripheral IM protein, Universal stress UP12 UspG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. PMID: 8740179 PMID: 9600841 PMID: 12071968 PMID: 16460009 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 12071968 PMID: 16460009 PMID: 19766000 PMID: 23230279 PMID: 8740179 PMID: 9600841 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic (Experimental) | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 53 | 0.335 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 85 | ||||||||
| YJGA_ECOLI | P0A8X0 | yjgA | b4234 JW4193 | cytoplasmic peripheral IM protein, UPF0307 YjgA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, ribosomal (Experimental) | PMID: 16980477 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm, ribosomal | A, F1, r | A,F1,r | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 46 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | |||||||||
| YAEH_ECOLI | P62768 | yaeH | b0163 JW0159 | cytoplasmic peripheral IM protein, UPF0325 YaeH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 26 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 93 | ||||||||||
| YIFE_ECOLI | P0ADN2 | yifE | b3764 JW3737 | cytoplasmic peripheral IM protein, UPF0438 YifE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 44 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||||
| YGIB_ECOLI | P0ADT2 | ygiB | b3037 JW5927 | cytoplasmic peripheral IM protein, UPF0441 YgiB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | YgiB and ygiC genes are expressed in the same operon as tolC and have homologues (yjfM and yjfC) located elsewhere on the chromosome. Mutational inactivation of the outer membrane channelTolC (a key component of multidrug efflux and type I secretion transporters) renders cells highly susceptible to antibiotics and leads to defects in secretion of protein toxins and the loss of TolC impairs cell division and growth in minimal glucose medium due to metabolic shutdown. The TolC-dependent phenotype was further exacerbated by the loss of ygiB and ygiC genes. YgiBC (and YjfMC) may have parallel but independent functions from TolC. Disulfide bond-containing protein PMID: 25664544 | PMID: 20545840 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 36 | 0.178 | SpII | 36 | 9.72422 | Pos+2=E | 0 | 0 | Y | n21-32c37/38o | Periplasmic | 9 | ||||||||||
| PYRH_ECOLI | P0A7E9 | pyrH smbA | smbA | b0171 JW0166 | cytoplasmic peripheral IM protein, Uridylate kinase PyrH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Fluorescent fusions of PyrH have been monitored via fluorescence microscopy. PyrH was found to be located in one membrane-associated foci per cell. PMID: 17272300 PyrH-EYFP fusions are predominantly localized near the bacterial membranes of different cells undergoing septation and division. PMID: 9922246 Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 17272300 PMID: 23230279 PMID: 9922246 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 23 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 30 | |||||||
| UVRA_ECOLI | P0A698 | uvrA dinE | dinE | b4058 JW4019 | cytoplasmic peripheral IM protein, UvrABC system A UvrA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (By similarity) | Homolog to import ATP-binding protein MalK. Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasm | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | TF | no | yes | No | 42 | 0.254 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||
| BTUD_ECOLI | P06611 | btuD | b1709 JW1699 | cytoplasmic peripheral IM protein, Vitamin B12 import ATP-binding BtuD | Vitamin B12 import ATP-binding protein btuD. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane; Peripheral membrane protein | Cytoplasmic | N/A | yes | yes | No | 26 | 0.195 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 9 | ||||||||||
| XGPT_ECOLI | P0A9M5 | gpt gpp gxu | gpp gxu | b0238 JW0228 | cytoplasmic peripheral IM protein, Xanthine phosphoribosyltransferase Gpt | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 48 | 0.21 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | |||||||||||
| XYLG_ECOLI | P37388 | xylG | b3567 JW3539 | cytoplasmic peripheral IM protein, Xylose import ATP-binding XylG | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | N/A | yes | yes | No | 20 | 0.188 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 48 | |||||||||||
| YAAY_ECOLI | P75620 | yaaY | b0024 JW5003 | cytoplasmic peripheral IM protein, YaaY | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Membrane anchored | N/A | no | yes | No | 43 | 0.125 | CYT | 0 | -0.200913 | - | 1 | 0 | N | i | CytoplasmicMembrane | 9 | ||||||||||||
| YAFS_ECOLI | P75672 | yafS | b0213 JW0203 | cytoplasmic peripheral IM protein, YafS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 54 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||||
| YAGA_ECOLI | P37007 | yagA | b0267 JW0260 | cytoplasmic peripheral IM protein, YagA | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | Prophage Integrase (EcoGene) | no | no | No | 29 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 2 | ||||||||
| YAHF_ECOLI | P77187 | yahF | b0320 JW0312 | cytoplasmic peripheral IM protein, YahF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 28 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||||
| YBJS_ECOLI | P75821 | ybjS | b0868 JW5819 | cytoplasmic peripheral IM protein, YbjS | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 30 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 6 | ||||||||||
| YBJX_ECOLI | P75829 | ybjX | b0877 JW0861 | cytoplasmic peripheral IM protein, YbjX | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | In Shigella the homologous protein is required for the expression, or correct membrane localisation of IcsA (VirG) on the bacterial cell surface.In Pasteurella haemolytica lapB (P32181), which is thought to be membrane-associated. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 20 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 21 | |||||||||
| YCAK_ECOLI | P43340 | ycaK | b0901 JW0884 | cytoplasmic peripheral IM protein, YcaK | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | no | yes | No | 23 | 0.238 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 95 | ||||||||||
| YDIJ_ECOLI | P77748 | ydiJ | b1687 JW1677 | cytoplasmic peripheral IM protein, YdiJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 15919657 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 29 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 2 | ||||||||||
| YEDJ_ECOLI | P46144 | yedJ | b1962 JW1945 | cytoplasmic peripheral IM protein, YedJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | no | yes | No | 65 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 116 | ||||||||||
| YFFO_ECOLI | P76546 | yffO | b2446 | cytoplasmic peripheral IM protein, YffO | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | Prophage Integrase (EcoGene) | no | no | No | 61 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||
| YFFR_ECOLI | P76549 | yffR | b2449 | cytoplasmic peripheral IM protein, YffR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | Prophage Integrase (EcoGene) | no | no | No | 20 | 0.169 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-14c19/20o | Unknown | 2 | |||||||||
| YFJP_ECOLI | P52131 | yfjP | b2632 JW5419 | cytoplasmic peripheral IM protein, YfjP | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Fluorescent fusions of YfjP have been monitored via fluorescence microscopy. YfjP located predominantly beside the membrane. | PMID: 17272300 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | no | no | No | 59 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 35 | ||||||||
| YGEH_ECOLI | P76639 | ygeH | b2852 JW2820 | cytoplasmic peripheral IM protein, YgeH | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Fluorescent fusions of YgeH have been monitored via fluorescence microscopy. YgeH located predominantly beside the membrane. | PMID: 17272300 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | no | yes | No | 53 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 19 | |||||||||
| YGGL_ECOLI | P38521 | yggL | b2959 JW2926 | cytoplasmic peripheral IM protein, YggL | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | N/A | yes | yes | No | 29 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 129 | ||||||||||
| YHGF_ECOLI | P46837 | yhgF | b3407 JW3370 | cytoplasmic peripheral IM protein, YhgF | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 24 | 0.217 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 90 | |||||||||
| YIEE_ECOLI | P0ADM8 | yieE | b3712 JW3690 | cytoplasmic peripheral IM protein, YieE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 25 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 7 | ||||||||||
| YIGI_ECOLI | P0ADP2 | yigI | b3820 JW5588 | cytoplasmic peripheral IM protein, YigI | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 19766000 PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected), Soluble IM Fraction + | yes | yes | No | 28 | 0.137 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 9 | |||||||||
| YJFM_ECOLI | P39295 | yjfM | b4185 JW4143 | cytoplasmic peripheral IM protein, YjfM | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | YgiB and ygiC genes are expressed in the same operon as tolC and have homologues (yjfM and yjfC) located elsewhere on the chromosome. Mutational inactivation of the outer membrane channelTolC (a key component of multidrug efflux and type I secretion transporters) renders cells highly susceptible to antibiotics and leads to defects in secretion of protein toxins and the loss of TolC impairs cell division and growth in minimal glucose medium due to metabolic shutdown. The TolC-dependent phenotype was further exacerbated by the loss of ygiB and ygiC genes. YgiBC (and YjfMC) may have parallel but independent functions from TolC. | PMID: 20545840 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | no | yes | No | 55 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 105 | |||||||||
| YJGR_ECOLI | P39342 | yjgR | b4263 JW4220 | cytoplasmic peripheral IM protein, YjgR | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted) | yes | yes | No | 58 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 87 | |||||||||
| YLBE_ECOLI | P77129 | ylbE | b4572 b0519 | cytoplasmic peripheral IM protein, YlbE | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | pseudogene (Ochman & Davalos, 2006) | no | yes | No | 46 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 33 | ||||||||
| YMFJ_ECOLI | P75973 | ymfJ | b1144 JW1130 | cytoplasmic peripheral IM protein, YmfJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Probable) | Experimentally detected by proteomics analysis of E.coli membrane fraction (Bernsel et al 2009). No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. Potential peripherally associated protein facing the cytoplasm or integral inner membrane protein. | PMID: 19766000 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | Prophage Integrase (EcoGene) | no | no | No | 48 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 47 | ||||||||
| YOBI_ECOLI | C1P604 | yobI | b4677 JW1850.1 | cytoplasmic peripheral IM protein, YobI | Small membrane protein detected experimentally | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | - | N/A | no | yes | No | 12 | 0.1 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| YSHB_ECOLI | C1P620 | yshB | b4686 JW3839.1 | cytoplasmic peripheral IM protein, YshB | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | Amphipaseek predicts N-terminal amphipathic helix (1-10). Amphipaseek predicts N-terminal amphipathic helix (1-10). | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | - | N/A | no | yes | No | 25 | 0.194 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||||
| ZNUC_ECOLI | P0A9X1 | znuC yebM | yebM | b1858 JW1847 | cytoplasmic peripheral IM protein, Zinc import ATP-binding ZnuC | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Experimental) | Detected in acossiation with the inner membrane (sequential biochemical fractionations coupled with high resolution mass spectrometry). PMID: 23230279 | PMID: 23230279 | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cell inner membrane | Cytoplasmic | Soluble protein detected in Inner Membrane Fraction | yes | yes | No | 22 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 15 | |||||||
| YDJJ_ECOLI | P77280 | ydjJ | b1774 JW1763 | cytoplasmic peripheral IM protein, zinc-type alcohol dehydrogenase-like YdjJ | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm (Potential) | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic, Peripheral inner membrane protein facing the cytoplasm | A, F1 | A,F1 | Cytoplasmic | IM (predicted-detected) | no | yes | No | 46 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 77 | ||||||||||
| PTRB_ECOLI | P24555 | ptrB tlp | tlp | b1845 JW1834 | cytoplasmic protease 2 PtrB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 17 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 5 | 1 | |||||||||||
| ELAD_ECOLI | Q47013 | elaD | b2269 JW5840 | cytoplasmic protease ElaD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 23 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 35 | ||||||||||||
| YEGQ_ECOLI | P76403 | yegQ | b2081 JW2066 | cytoplasmic protease YegQ | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 22 | 0.362 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 74 | ||||||||||||
| YHBU_ECOLI | P45527 | yhbU | b3158 JW3127 | cytoplasmic protease YhbU | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 24 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 9 | ||||||||||||
| HSCA_ECOLI | P0A6Z1 | hscA hsc | hsc | b2526 JW2510 | cytoplasmic protein of Hsp70 family, Chaperone HscA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.165 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 101 | |||||||||||
| HSCC_ECOLI | P77319 | hscC ybeW | ybeW | b0650 JW0645 | cytoplasmic protein of Hsp70 family, Chaperone HscC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 21 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 74 | |||||||||||
| YEGD_ECOLI | P36928 | yegD | b2069 JW2054 | cytoplasmic protein of Hsp70 family, Chaperone YegD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 46 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 8 | ||||||||||||
| LSRG_ECOLI | P64461 | lsrG yneC | yneC | b1518 JW1511 | cytoplasmic protein, (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase LsrG | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 33 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 76 | ||||||||||
| CITC_ECOLI | P77390 | citC ybeO | ybeO | b0618 JW0610 | cytoplasmic protein, (Citrate (pro-3S)-lyase) ligase CitC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 64 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 84 | |||||||||||
| PAAG_ECOLI | P77467 | paaG ydbT | ydbT | b1394 JW1389 | cytoplasmic protein, 1,2-epoxyphenylacetyl-CoA isomerase PaaG | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 62 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 98 | |||||||||||
| PAAA_ECOLI | P76077 | paaA ydbO | ydbO | b1388 JW1383 | cytoplasmic protein, 1,2-phenylacetyl-CoA epoxidase, subunit A PaaA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 29 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||||||
| PAAB_ECOLI | P76078 | paaB ynbF | ynbF | b1389 JW1384 | cytoplasmic protein, 1,2-phenylacetyl-CoA epoxidase, subunit B PaaB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 30 | 0.214 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 86 | |||||||||||
| PAAE_ECOLI | P76081 | paaE ydbR | ydbR | b1392 JW1387 | cytoplasmic protein, 1,2-phenylacetyl-CoA epoxidase, subunit E PaaE | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 26 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 21 | |||||||||||
| GLGB_ECOLI | P07762 | glgB | b3432 JW3395 | cytoplasmic protein, 1,4-alpha-glucan branching enzyme GlgB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 27 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | ||||||||||||
| MENI_ECOLI | P77781 | menI ydiI | ydiI | b1686 JW1676 | cytoplasmic protein, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase MenI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 63 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 78 | |||||||||||
| MENB_ECOLI | P0ABU0 | menB | b2262 JW2257 | cytoplasmic protein, 1,4-dihydroxy-2-naphthoyl-CoA synthase MenB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 62 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 71 | ||||||||||||
| AMPD_ECOLI | P13016 | ampD | b0110 JW0106 | cytoplasmic protein, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 45 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 60 | |||||||||||
| HIS4_ECOLI | P10371 | hisA | b2024 JW2006 | cytoplasmic protein, 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase HisA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 55 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 44 | |||||||||||
| DXR_ECOLI | P45568 | dxr ispC yaeM | ispC yaeM | b0173 JW0168 | cytoplasmic protein, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | no | yes | No | 55 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | |||||||||||
| YAJO_ECOLI | P77735 | yajO | b0419 JW0409 | cytoplasmic protein, 1-deoxyxylulose-5-phosphate synthase YajO | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 33 | 0.138 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 4 | ||||||||||||
| K1PF_ECOLI | P0AEW9 | fruK fpk | fpk | b2168 JW2155 | cytoplasmic protein, 1-phosphofructokinase FruK | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 39 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 79 | |||||||||||
| GPMI_ECOLI | P37689 | gpmI pgmI yibO | pgmI yibO | b3612 JW3587 | cytoplasmic protein, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GpmI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 20 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 104 | |||||||||||
| PAAF_ECOLI | P76082 | paaF ydbR | ydbR | b1393 JW1388 | cytoplasmic protein, 2,3-dehydroadipyl-CoA hydratase PaaF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 41 | 0.148 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 71 | |||||||||||
| ENTA_ECOLI | P15047 | entA | b0596 JW0588 | cytoplasmic protein, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase EntA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 31 | 0.19 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 63 | ||||||||||||
| MHPB_ECOLI | P0ABR9 | mhpB | b0348 JW0339 | cytoplasmic protein, 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase MhpB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 23 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 8 | ||||||||||||
| DLGD_ECOLI | P37672 | dlgD yiaK | yiaK | b3575 JW3547 | cytoplasmic protein, 2,3-diketo-L-gulonate reductase DlgD | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 29 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 36 | ||||||||||
| FADH_ECOLI | P42593 | fadH ygjL | ygjL | b3081 JW3052 | cytoplasmic protein, 2,4-dienoyl-CoA reductase FadH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 20 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 17 | |||||||||||
| DKGA_ECOLI | Q46857 | dkgA yqhE | yqhE | b3012 JW5499 | cytoplasmic protein, 2,5-diketo-D-gluconic acid reductase A DkgA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 26 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 27 | ||||||||||
| DKGB_ECOLI | P30863 | dkgB yafB | yafB | b0207 JW0197 | cytoplasmic protein, 2,5-diketo-D-gluconic acid reductase B DkgB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 37 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 78 | ||||||||||
| CITG_ECOLI | P77231 | citG ybdT | ybdT | b0613 JW0605 | cytoplasmic protein, 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase CitG | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 65 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 5 | |||||||||||
| HPPK_ECOLI | P26281 | folK | b0142 JW0138 | cytoplasmic protein, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.266 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 66 | ||||||||||||
| ISPF_ECOLI | P62617 | ispF mecS ygbB | mecS ygbB | b2746 JW2716 | cytoplasmic protein, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 12 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 84 | |||||||||||
| ISPD_ECOLI | Q46893 | ispD ygbP | ygbP | b2747 JW2717 | cytoplasmic protein, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD | Copurifies with trigger factor in pull down assays. | Cytoplasmic | A | A | Cytoplasmic | N/A | TF | yes | yes | No | 47 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 67 | |||||||||
| DGOA_ECOLI | Q6BF16 | dgoA yidU | yidU | b4477 JW5628 | cytoplasmic protein, 2-dehydro-3-deoxy-6-phosphogalactonate aldolase DgoA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 24 | 0.37 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | |||||||||||
| KDUD_ECOLI | P37769 | kduD ygeC yqeD | ygeC yqeD | b2842 JW2810 | cytoplasmic protein, 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 34 | 0.193 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 70 | |||||||||||
| DGOK_ECOLI | P31459 | dgoK yidV | yidV | b3693 JW3670 | cytoplasmic protein, 2-dehydro-3-deoxygalactonokinase DgoK | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | no | yes | No | 34 | 0.174 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 7 | |||||||||||
| KDGK_ECOLI | P37647 | kdgK yhjI | yhjI | b3526 JW5668 | cytoplasmic protein, 2-dehydro-3-deoxygluconokinase KdgK | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 54 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| KDSA_ECOLI | P0A715 | kdsA | b1215 JW1206 | cytoplasmic protein, 2-dehydro-3-deoxyphosphooctonate aldolase KdsA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 56 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 29 | |||||||||||
| PANE_ECOLI | P0A9J4 | panE apbA | apbA | b0425 JW0415 | cytoplasmic protein, 2-dehydropantoate 2-reductase PanE | Cytoplasmic (By similarity) Cytoplasmic (Experimental) | Phobious predicts the sequence that follows signal peptide as non cytoplasmic and non transmembrane. The native enzyme exists in solution as a monomer with a molecular mass of 34 000 Da. PMID: 10736170 Lipoprotein PMID: 10572132 PMID: 15174130 PMID: 10736170 | PMID: 10572132 PMID: 15174130 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic (Experimental) | IM (predicted) | LOL: Localization Of Lipoproteins | yes | yes | No | 21 | 0.133 | SpII | 19 | 2.5798 | Pos+2=K | 0 | 0 | Y | n5-16c20/21o | Cytoplasmic | 8 | 31 | ||||||
| GARR_ECOLI | P0ABQ2 | garR yhaE | yhaE | b3125 JW5526 | cytoplasmic protein, 2-hydroxy-3-oxopropionate reductase GarR | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 38 | 0.214 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 90 | |||||||||||
| GLXR_ECOLI | P77161 | glxR glxB1 ybbQ | glxB1 ybbQ | b0509 JW0497 | cytoplasmic protein, 2-hydroxy-3-oxopropionate reductase GlxR | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 23 | 0.151 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-10c22/23o | Cytoplasmic | 9 | 71 | |||||||||||
| MHPC_ECOLI | P77044 | mhpC | b0349 JW0340 | cytoplasmic protein, 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase MhpC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 52 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 16 | ||||||||||||
| THIH_ECOLI | P30140 | thiH | b3990 JW3953 | cytoplasmic protein, 2-iminoacetate synthase ThiH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 26 | 0.141 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||||||
| LEU1_ECOLI | P09151 | leuA | b0074 JW0073 | cytoplasmic protein, 2-isopropylmalate synthase LeuA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 35 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | ||||||||||||
| RHMA_ECOLI | P76469 | rhmA yfaU | yfaU | b2245 JW2239 | cytoplasmic protein, 2-keto-3-deoxy-L-rhamnonate aldolase RhmA | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 32 | 0.417 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | |||||||||||
| MHPD_ECOLI | P77608 | mhpD | b0350 JW0341 | cytoplasmic protein, 2-keto-4-pentenoate hydratase MhpD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 38 | 0.173 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 74 | ||||||||||||
| PRPD_ECOLI | P77243 | prpD yahT | yahT | b0334 JW0325 | cytoplasmic protein, 2-methylcitrate dehydratase PrpD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 34 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 10 | |||||||||||
| PRPC_ECOLI | P31660 | prpC yahS yzzD | yahS yzzD | b0333 JW0324 | cytoplasmic protein, 2-methylcitrate synthase PrpC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 34 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | |||||||||||
| UBIF_ECOLI | P75728 | ubiF yleB | yleB | b0662 JW0659 | cytoplasmic protein, 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 31 | 0.178 | TMH | 0 | 1.41397 | - | 0 | 0 | N | i | Unknown | 2 | 14 | ||||||||||
| UBII_ECOLI | P25535 | ubiI visC | visC | b2906 JW2874 | cytoplasmic protein, 2-octaprenylphenol hydroxylase UbiI | Uncharacterized conserved visC gene is involved in Q biosynthesis in Escherichia coli (renamed as ubiI). Coenzyme Q (ubiquinone or Q) is a widespread redox-active lipid essential for electron and proton transport in the respiratory chains from bacteria to mammals. VisC/UbiL protein functions in the C5-hydroxylation reaction. | Cytoplasmic | A | A | Membrane Lipoprotein | IM (predicted-detected) | LOL: Localization Of Lipoproteins | yes | yes | No | 20 | 0.198 | SpII | 19 | 0.428013 | Pos+2=G | 0 | 0 | N | i | Cytoplasmic | 9 | 49 | |||||||||
| OTNI_ECOLI | Q46891 | otnI ygbM | ygbM | b2739 JW2709 | cytoplasmic protein, 2-oxo-tetronate isomerase OtnI | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 69 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 14 | |||||||||||
| MEND_ECOLI | P17109 | menD | b2264 JW5374 | cytoplasmic protein, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase MenD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 41 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 3 | ||||||||||||
| MENH_ECOLI | P37355 | menH yfbB | yfbB | b2263 JW2258 | cytoplasmic protein, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 30 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| RLMA_ECOLI | P36999 | rlmA rrmA yebH | rrmA yebH | b1822 JW1811 | cytoplasmic protein, 23S rRNA (guanine(745)-N(1))-methyltransferase RlmA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 10 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 36 | |||||||||||
| RLMC_ECOLI | P75817 | rlmC rumB ybjF | rumB ybjF | b0859 JW0843 | cytoplasmic protein, 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC | Translation, Ribosomal. | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 28 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | ||||||||||
| YDCP_ECOLI | P76104 | ydcP | b1435 JW1431 | cytoplasmic protein, 23S rRNA 5-hydroxycytidine C2501 synthase YdcP | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 18 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 13 | ||||||||||||
| RLMB_ECOLI | P63177 | rlmB yjfH | yjfH | b4180 JW4138 | cytoplasmic protein, 23S rRNA RlmB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 24 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 93 | ||||||||||
| RLMD_ECOLI | P55135 | rlmD rumA ygcA | rumA ygcA | b2785 JW2756 | cytoplasmic protein, 23S rRNA RlmD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 51 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||||
| FER_ECOLI | P0A9R4 | fdx | b2525 JW2509 | cytoplasmic protein, 2Fe-2S ferredoxin Fdx | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 42 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 82 | ||||||||||||
| CPDA_ECOLI | P0AEW4 | cpdA icc | icc | b3032 JW3000 | cytoplasmic protein, 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 67 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 60 | |||||||||||
| TATD_ECOLI | P27859 | tatD mttC yigW yigX | mttC yigW yigX | b4483 JW5931 | cytoplasmic protein, 3'-5' ssDNA/RNA exonuclease TatD | Cytoplasmic (Experimental) Cytoplasmic (Probable) | PMID: 10747959 PMID: 9298646 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic (Experimental) | N/A | pseudogene (Ochman & Davalos, 2006) | no | yes | No | 15 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||
| MHPA_ECOLI | P77397 | mhpA | b0347 JW0338 | cytoplasmic protein, 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase MhpA | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | no | yes | No | 32 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 7 | ||||||||||||
| AROD_ECOLI | P05194 | aroD | b1693 JW1683 | cytoplasmic protein, 3-dehydroquinate dehydratase AroD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 37 | 0.183 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 97 | ||||||||||||
| AROB_ECOLI | P07639 | aroB | b3389 JW3352 | cytoplasmic protein, 3-dehydroquinate synthase AroB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 29 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 22 | |||||||||||
| KDSB_ECOLI | P04951 | kdsB | b0918 JW0901 | cytoplasmic protein, 3-deoxy-manno-octulosonate cytidylyltransferase KdsB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 61 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 115 | |||||||||||
| LSRF_ECOLI | P76143 | lsrF yneB | yneB | b1517 JW1510 | cytoplasmic protein, 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase LsrF | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 56 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 33 | ||||||||||
| PAAH_ECOLI | P76083 | paaH ydbU | ydbU | b1395 JW1390 | cytoplasmic protein, 3-hydroxyadipyl-CoA dehydrogenase PaaH | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | no | yes | No | 41 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 7 | ||||||||||
| FABA_ECOLI | P0A6Q3 | fabA | b0954 JW0937 | cytoplasmic protein, 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase FabA | Trigger factor-sensitive aggregation. Copurifies with trigger factor in pull down assays. | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 31 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 65 | |||||||||
| LEUC_ECOLI | P0A6A6 | leuC | b0072 JW0071 | cytoplasmic protein, 3-isopropylmalate dehydratase large subunit LeuC | Disulfide bond-containing protein PMID: 25664544 | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 41 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 70 | |||||||||||
| LEUD_ECOLI | P30126 | leuD | b0071 JW0070 | cytoplasmic protein, 3-isopropylmalate dehydratase small subunit LeuD | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | no | yes | No | 18 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | ||||||||||||
| LEU3_ECOLI | P30125 | leuB | b0073 JW5807 | cytoplasmic protein, 3-isopropylmalate dehydrogenase LeuB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 22 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 58 | |||||||||||
| SGBH_ECOLI | P37678 | sgbH yiaQ | yiaQ | b3581 JW3553 | cytoplasmic protein, 3-keto-L-gulonate-6-phosphate decarboxylase SgbH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.147 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 41 | |||||||||||
| ULAD_ECOLI | P39304 | ulaD sgaH yjfV | sgaH yjfV | b4196 JW4154 | cytoplasmic protein, 3-keto-L-gulonate-6-phosphate decarboxylase UlaD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 47 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||||||
| FADA_ECOLI | P21151 | fadA oldA | oldA | b3845 JW5578 | cytoplasmic protein, 3-ketoacyl-CoA thiolase FadA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 28 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 10 | ||||||||||
| THTM_ECOLI | P31142 | sseA | b2521 JW2505 | cytoplasmic protein, 3-mercaptopyruvate sulfurtransferase SseA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 10 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 5 | ||||||||||||
| PANB_ECOLI | P31057 | panB | b0134 JW0130 | cytoplasmic protein, 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 35 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 43 | |||||||||||
| OTNC_ECOLI | Q46890 | otnC ygbL | ygbL | b2738 JW2708 | cytoplasmic protein, 3-oxo-tetronate 4-phosphate decarboxylase OtnC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 47 | 0.21 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 56 | |||||||||||
| OTNK_ECOLI | Q46889 | otnK ygbK | ygbK | b2737 JW2707 | cytoplasmic protein, 3-oxo-tetronate kinase OtnK | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 61 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 20 | |||||||||||
| FABH_ECOLI | P0A6R0 | fabH | b1091 JW1077 | cytoplasmic protein, 3-oxoacyl-(acyl-carrier-protein) synthase 3 FabH | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 21 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 91 | |||||||||||
| PAAJ_ECOLI | P0C7L2 | paaJ paaE ydbW | paaE ydbW | b1397 JW1392 | cytoplasmic protein, 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase PaaJ | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 46 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | |||||||||||
| HCAB_ECOLI | P0CI31 | hcaB phdD yfhX | phdD yfhX | b2541 JW2525 | cytoplasmic protein, 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase HcaB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 34 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | |||||||||||
| HCAC_ECOLI | P0ABW0 | hcaC hcaA3 phdB yfhW | hcaA3 phdB yfhW | b2540 JW2524 | cytoplasmic protein, 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit HcaC | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 38 | 0.146 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 112 | |||||||||||
| HCAD_ECOLI | P77650 | hcaD hcaA4 phdA yfhY | hcaA4 phdA yfhY | b2542 JW2526 | cytoplasmic protein, 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component HcaD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 29 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 40 | |||||||||||
| HCAE_ECOLI | P0ABR5 | hcaE digA hcaA hcaA1 phdC1 yfhU | digA hcaA hcaA1 phdC1 yfhU | b2538 JW2522 | cytoplasmic protein, 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha HcaE | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 48 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 13 | |||||||||||
| HCAF_ECOLI | Q47140 | hcaF digB hcaA2 hcaB phdC2 yfhV | digB hcaA2 hcaB phdC2 yfhV | b2539 JW2523 | cytoplasmic protein, 3-phenylpropionate/cinnamic acid dioxygenase subunit beta HcaF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 51 | 0.125 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | |||||||||||
| AROA_ECOLI | P0A6D3 | aroA | b0908 JW0891 | cytoplasmic protein, 3-phosphoshikimate 1-carboxyvinyltransferase AroA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 38 | 0.15 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 61 | |||||||||||
| SQUU_ECOLI | P0A9V8 | yihU | b3882 JW3853 | cytoplasmic protein, 3-sulfolactaldehyde reductase YihU | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.352 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n2-9c17/18o | Cytoplasmic | 9 | 14 | ||||||||||||
| ACPT_ECOLI | P37623 | acpT yhhU | yhhU | b3475 JW3440 | cytoplasmic protein, 4'-phosphopantetheinyl transferase AcpT | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 63 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 13 | |||||||||||
| YGID_ECOLI | P24197 | ygiD | b3039 JW3007 | cytoplasmic protein, 4,5-DOPA dioxygenase extradiol YgiD | Cytoplasmic | A | A | Cytoplasm | Integral Membrane Protein | N/A | yes | yes | No | 22 | 0.203 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| PUUE_ECOLI | P50457 | puuE goaG | goaG | b1302 JW1295 | cytoplasmic protein, 4-aminobutyrate aminotransferase PuuE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 29 | 0.166 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 42 | |||||||||||
| KDUI_ECOLI | Q46938 | kduI yqeE | yqeE | b2843 JW2811 | cytoplasmic protein, 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 13 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 63 | |||||||||||
| ISPE_ECOLI | P62615 | ispE ipk ychB | ipk ychB | b1208 JW1199 | cytoplasmic protein, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 23 | 0.205 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 99 | |||||||||||
| HOA_ECOLI | P51020 | mhpE | b0352 JW0343 | cytoplasmic protein, 4-hydroxy-2-oxovalerate aldolase MhpE | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 50 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 9 | ||||||||||||
| ISPH_ECOLI | P62623 | ispH lytB yaaE | lytB yaaE | b0029 JW0027 | cytoplasmic protein, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 28 | 0.217 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 75 | |||||||||||
| DAPB_ECOLI | P04036 | dapB | b0031 JW0029 | cytoplasmic protein, 4-hydroxy-tetrahydrodipicolinate reductase DapB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 25 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 94 | |||||||||||
| DAPA_ECOLI | P0A6L2 | dapA | b2478 JW2463 | cytoplasmic protein, 4-hydroxy-tetrahydrodipicolinate synthase DapA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||||
| PDXA_ECOLI | P19624 | pdxA | b0052 JW0051 | cytoplasmic protein, 4-hydroxythreonine-4-phosphate dehydrogenase PdxA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 66 | 0.214 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 94 | |||||||||||
| RNAAM_ECOLI | P77766 | yciV trpH | trpH | b1266 JW1258 | cytoplasmic protein, 5'-3' exoribonuclease YciV | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 21 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 58 | |||||||||||
| 5DNU_ECOLI | P76491 | yfbR | b2291 JW2288 | cytoplasmic protein, 5'-deoxynucleotidase YfbR | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 46 | 0.185 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 67 | |||||||||||
| MTNN_ECOLI | P0AF12 | mtnN mtn pfs yadA | mtn pfs yadA | b0159 JW0155 | cytoplasmic protein, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase MtnN | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 56 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 106 | |||||||||||
| SURE_ECOLI | P0A840 | surE ygbC | ygbC | b2744 JW2714 | cytoplasmic protein, 5'/3'-nucleotidase SurE | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 34 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 40 | ||||||||||
| METF_ECOLI | P0AEZ1 | metF | b3941 JW3913 | cytoplasmic protein, 5,10-methylenetetrahydrofolate reductase MetF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 25 | ||||||||||||
| YBJI_ECOLI | P75809 | ybjI | b0844 JW5113 | cytoplasmic protein, 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 66 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 59 | ||||||||||||
| YIGB_ECOLI | P0ADP0 | yigB | b3812 JW3785 | cytoplasmic protein, 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB | Cytoplasmic | A | A | Cytoplasmic | N/A | Prophage Integrase | yes | no | No | 26 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | |||||||||||
| 5FCL_ECOLI | P0AC28 | ygfA | b2912 JW2879 | cytoplasmic protein, 5-formyltetrahydrofolate cyclo-ligase YgfA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 35 | 0.242 | CYT | 0 | -0.200913 | - | 0 | 2 | N | i21-43o63-81i | Unknown | 2 | 9 | ||||||||||||
| GARL_ECOLI | P23522 | garL yhaF | yhaF | b3126 JW3095 | cytoplasmic protein, 5-keto-4-deoxy-D-glucarate aldolase GarL | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 29 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||||
| IDNO_ECOLI | P0A9P9 | idnO yjgU | yjgU | b4266 JW4223 | cytoplasmic protein, 5-keto-D-gluconate 5-reductase IdnO | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 21 | 0.181 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 48 | |||||||||||
| MCRA_ECOLI | P24200 | mcrA rglA | rglA | b1159 JW1145 | cytoplasmic protein, 5-methylcytosine-specific restriction enzyme A McrA | Cytoplasmic | A | A | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | no | no | No | 39 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 39 | ||||||||||
| METE_ECOLI | P25665 | metE | b3829 JW3805 | cytoplasmic protein, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 23 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 33 | ||||||||||||
| YBGL_ECOLI | P75746 | ybgL | b0713 JW0703 | cytoplasmic protein, 5-oxoprolinase subunit A YbgL | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 30 | 0.197 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 11 | ||||||||||||
| YBGJ_ECOLI | P0AAV4 | ybgJ | b0711 JW0701 | cytoplasmic protein, 5-oxoprolinase subunit B YbgJ | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 26 | 0.194 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | ||||||||||||
| YBGK_ECOLI | P75745 | ybgK | b0712 JW0702 | cytoplasmic protein, 5-oxoprolinase subunit C YbgK | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 51 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | ||||||||||||
| ROXA_ECOLI | P27431 | roxA ycfD | ycfD | b1128 JW1114 | cytoplasmic protein, 50S L16 3-hydroxylase RoxA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 42 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 81 | |||||||||||
| PRMB_ECOLI | P39199 | prmB yfcB | yfcB | b2330 JW5841 | cytoplasmic protein, 50S L3 glutamine methyltransferase PrmB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 38 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 32 | |||||||||||
| QUED_ECOLI | P65870 | queD ygcM | ygcM | b2765 JW2735 | cytoplasmic protein, 6-carboxy-5,6,7,8-tetrahydropterin synthase QueD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 90 | |||||||||||
| ASCB_ECOLI | P24240 | ascB | b2716 JW2686 | cytoplasmic protein, 6-phospho-beta-glucosidase AscB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 16 | 0.219 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 28 | ||||||||||||
| BGLA_ECOLI | Q46829 | bglA bglD yqfC | bglD yqfC | b2901 JW2869 | cytoplasmic protein, 6-phospho-beta-glucosidase BglA | Trigger factor-sensitive aggregation. | Cytoplasmic | A | A | Cytoplasmic | N/A | TF | yes | yes | No | 20 | 0.217 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 69 | |||||||||
| BGLB_ECOLI | P11988 | bglB | b3721 JW3699 | cytoplasmic protein, 6-phospho-beta-glucosidase BglB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 16 | 0.139 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 19 | ||||||||||||
| CHBF_ECOLI | P17411 | chbF celF ydjD | celF ydjD | b1734 JW1723 | cytoplasmic protein, 6-phospho-beta-glucosidase ChbF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 63 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 24 | |||||||||||
| YIEH_ECOLI | P31467 | yieH | b3715 JW3693 | cytoplasmic protein, 6-phosphogluconate phosphatase YieH | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 68 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 23 | ||||||||||||
| 6PGL_ECOLI | P52697 | pgl ybhE | ybhE | b0767 JW0750 | cytoplasmic protein, 6-phosphogluconolactonase Pgl | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 41 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Periplasmic | 9 | 84 | |||||||||||
| HDHA_ECOLI | P0AET8 | hdhA hsdH | hsdH | b1619 JW1611 | cytoplasmic protein, 7-alpha-hydroxysteroid dehydrogenase HdhA | Disulfide bond-containing protein PMID: 25664544 | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 48 | 0.2 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 68 | ||||||||||
| QUEE_ECOLI | P64554 | queE ygcF | ygcF | b2777 JW2748 | cytoplasmic protein, 7-carboxy-7-deazaguanine synthase QueE | Old gene name YgaW. | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 39 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 63 | ||||||||||
| QUEC_ECOLI | P77756 | queC ybaX | ybaX | b0444 JW0434 | cytoplasmic protein, 7-cyano-7-deazaguanine synthase QueC | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 22 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 104 | |||||||||||
| BIOF_ECOLI | P12998 | bioF | b0776 JW0759 | cytoplasmic protein, 8-amino-7-oxononanoate synthase BioF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 30 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 3 | ||||||||||||
| MUTT_ECOLI | P08337 | mutT | b0099 JW0097 | cytoplasmic protein, 8-oxo-dGTP diphosphatase MutT | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 25 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 107 | ||||||||||||
| ACDH_ECOLI | P77580 | mhpF mhpE | mhpE | b0351 JW0342 | cytoplasmic protein, Acetaldehyde dehydrogenase MhpF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 70 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 58 | |||||||||||
| ATOD_ECOLI | P76458 | atoD | b2221 JW2215 | cytoplasmic protein, Acetate CoA-transferase subunit alpha AtoD | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 39 | 0.125 | TMH | 0 | 0.259434 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 54 | ||||||||||||
| ATOA_ECOLI | P76459 | atoA | b2222 JW2216 | cytoplasmic protein, Acetate CoA-transferase subunit beta AtoA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 61 | 0.12 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 25 | ||||||||||||
| YDIF_ECOLI | P37766 | ydiF | b1694 JW1684 | cytoplasmic protein, Acetate CoA-transferase YdiF YdiF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 52 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 33 | ||||||||||||
| ILVB_ECOLI | P08142 | ilvB | b3671 JW3646 | cytoplasmic protein, Acetolactate synthase isozyme 1 large subunit IlvB | Disulfide bond-containing protein PMID: 25664544 | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 45 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 29 | |||||||||||
| ILVN_ECOLI | P0ADF8 | ilvN | b3670 JW3645 | cytoplasmic protein, Acetolactate synthase isozyme 1 small subunit IlvN | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 36 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 99 | ||||||||||||
| ILVM_ECOLI | P0ADG1 | ilvM | b3769 JW3742 | cytoplasmic protein, Acetolactate synthase isozyme 2 small subunit IlvM | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 43 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 57 | ||||||||||||
| ILVI_ECOLI | P00893 | ilvI | b0077 JW0076 | cytoplasmic protein, Acetolactate synthase isozyme 3 large subunit IlvI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 25 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 3 | ||||||||||||
| ILVH_ECOLI | P00894 | ilvH brnP | brnP | b0078 JW0077 | cytoplasmic protein, Acetolactate synthase isozyme 3 small subunit IlvH | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 18 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-9c17/18o | Cytoplasmic | 9 | 15 | |||||||||||
| AES_ECOLI | P23872 | aes ybaC | ybaC | b0476 JW0465 | cytoplasmic protein, Acetyl esterase Aes | Cytoplasmic (Probable) | PMID: 9576853 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 34 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 34 | ||||||||
| ATOB_ECOLI | P76461 | atoB | b2224 JW2218 | cytoplasmic protein, Acetyl-CoA acetyltransferase AtoB | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 23 | 0.375 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 8 | |||||||||||
| ACOCT_ECOLI | P76518 | yfdE | b2371 JW2368 | cytoplasmic protein, Acetyl-CoA:oxalate CoA-transferase YfdE | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | yes | yes | No | 48 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 36 | |||||||||||
| ARGD_ECOLI | P18335 | argD dapC dtu | dapC dtu | b3359 JW3322 | cytoplasmic protein, Acetylornithine/succinyldiaminopimelate aminotransferase ArgD | Copurifies with trigger factor in pull down assays. | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 25 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 29 | ||||||||
| YDCK_ECOLI | P76100 | ydcK | b1428 JW1424 | cytoplasmic protein, Acetyltransferase YdcK | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 55 | 0.163 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 18 | ||||||||||||
| YPEA_ECOLI | P76539 | ypeA | b2434 JW2427 | cytoplasmic protein, Acetyltransferase YpeA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 53 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 80 | ||||||||||||
| MSYB_ECOLI | P25738 | msyB | b1051 JW1039 | cytoplasmic protein, Acidic MsyB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 56 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 91 | ||||||||||||
| ACNA_ECOLI | P25516 | acnA acn | acn | b1276 JW1268 | cytoplasmic protein, Aconitate hydratase A AcnA | Cytoplasmic (Experimental) | PMID: 10585860 | Cytoplasmic | A | A | Cytoplasmic (Experimental) | N/A | no | yes | No | 47 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 40 | |||||||||
| ACPH_ECOLI | P21515 | acpH yajB | yajB | b0404 JW0394 | cytoplasmic protein, Acyl carrier phosphodiesterase AcpH | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 24 | 0.265 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-13c23/24o | Cytoplasmic | 8 | 13 | |||||||||||
| LPXA_ECOLI | P0A722 | lpxA | b0181 JW0176 | cytoplasmic protein, Acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase LpxA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 25 | 0.206 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 21 | |||||||||||
| YCIA_ECOLI | P0A8Z0 | yciA | b1253 JW1245 | cytoplasmic protein, Acyl-CoA thioester hydrolase YciA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 26 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 79 | ||||||||||||
| TESB_ECOLI | P0AGG2 | tesB | b0452 JW0442 | cytoplasmic protein, Acyl-CoA thioesterase 2 TesB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 47 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 23 | ||||||||||||
| PAAI_ECOLI | P76084 | paaI ydbV | ydbV | b1396 JW1391 | cytoplasmic protein, Acyl-coenzyme A thioesterase PaaI | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 68 | 0.192 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 76 | |||||||||||
| ACYP_ECOLI | P0AB65 | yccX | b0968 JW5131 | cytoplasmic protein, Acylphosphatase YccX | Disulfide bridge (5 49) PMID: 17134700 | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 28 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-11c16/17o | Cytoplasmic | 9 | 103 | |||||||||||
| ADEC_ECOLI | P31441 | ade yicP | yicP | b3665 JW3640 | cytoplasmic protein, Adenine deaminase Ade | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | no | yes | No | 31 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 34 | |||||||||||
| MUTY_ECOLI | P17802 | mutY micA | micA | b2961 JW2928 | cytoplasmic protein, Adenine DNA glycosylase MutY | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 58 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | |||||||||||
| APT_ECOLI | P69503 | apt | b0469 JW0458 | cytoplasmic protein, Adenine phosphoribosyltransferase Apt | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 56 | 0.174 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 89 | |||||||||||
| COBC_ECOLI | P52086 | cobC phpB | phpB | b0638 JW0633 | cytoplasmic protein, Adenosylcobalamin/alpha-ribazole phosphatase CobC | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 36 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 35 | |||||||||||
| BIOA_ECOLI | P12995 | bioA | b0774 JW0757 | cytoplasmic protein, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 55 | 0.168 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 21 | |||||||||||
| CYAA_ECOLI | P00936 | cyaA cya | cya | b3806 JW3778 | cytoplasmic protein, Adenylate cyclase CyaA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 26 | 0.196 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||||
| CYSC_ECOLI | P0A6J1 | cysC | b2750 JW2720 | cytoplasmic protein, Adenylyl-sulfate kinase CysC | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 48 | 0.15 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 83 | ||||||||||||
| NUDE_ECOLI | P45799 | nudE yrfE | yrfE | b3397 JW3360 | cytoplasmic protein, ADP compounds hydrolase NudE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 70 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | |||||||||||
| AEGA_ECOLI | P37127 | aegA yffG | yffG | b2468 JW2452 | cytoplasmic protein, AegA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 21 | |||||||||||
| SPEB_ECOLI | P60651 | speB | b2937 JW2904 | cytoplasmic protein, Agmatinase SpeB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 53 | 0.127 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 67 | ||||||||||||
| ALR1_ECOLI | P0A6B4 | alr | b4053 JW4013 | cytoplasmic protein, Alanine racemase, biosynthetic Alr | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 38 | 0.208 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 46 | ||||||||||||
| ALDB_ECOLI | P37685 | aldB yiaX | yiaX | b3588 JW3561 | cytoplasmic protein, Aldehyde dehydrogenase B AldB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 38 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||||
| AHR_ECOLI | P27250 | ahr yjgB | yjgB | b4269 JW5761 | cytoplasmic protein, Aldehyde reductase Ahr | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | no | yes | No | 21 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 52 | ||||||||||
| GALM_ECOLI | P0A9C3 | galM | b0756 JW0739 | cytoplasmic protein, Aldose 1-epimerase GalM | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 10 | 0.161 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Periplasmic | 10 | 104 | |||||||||||
| SSUD_ECOLI | P80645 | ssuD ycbN | ycbN | b0935 JW0918 | cytoplasmic protein, Alkanesulfonate monooxygenase SsuD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 39 | 0.14 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | ||||||||||||
| ALLC_ECOLI | P77425 | allC glxB7 ylbB | glxB7 ylbB | b0516 JW0504 | cytoplasmic protein, Allantoate amidohydrolase AllC | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 24 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 25 | ||||||||||
| ALLB_ECOLI | P77671 | allB glxB3 ybbX | glxB3 ybbX | b0512 JW0500 | cytoplasmic protein, Allantoinase AllB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 32 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 106 | |||||||||||
| ALLE_ECOLI | P75713 | allE glxB6 ylbA | glxB6 ylbA | b0515 JW0503 | cytoplasmic protein, AllE | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 28 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||||
| YIHX_ECOLI | P0A8Y3 | yihX | b3885 JW5566 | cytoplasmic protein, Alpha-D-glucose 1-phosphate phosphatase YihX | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.142 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | |||||||||||||
| PHNJ_ECOLI | P16688 | phnJ | b4098 JW4059 | cytoplasmic protein, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase PhnJ | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 11 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 8 | ||||||||||||
| PHNM_ECOLI | P16689 | phnM | b4095 JW4056 | cytoplasmic protein, Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 31 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 9 | ||||||||||||
| PHNG_ECOLI | P16685 | phnG | b4101 JW4062 | cytoplasmic protein, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 25 | 0.134 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 26 | ||||||||||||
| PHNH_ECOLI | P16686 | phnH | b4100 JW4061 | cytoplasmic protein, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 65 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 48 | ||||||||||||
| PHNI_ECOLI | P16687 | phnI | b4099 JW4060 | cytoplasmic protein, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 18 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 10 | ||||||||||||
| AGAL_ECOLI | P06720 | melA mel-7 | mel-7 | b4119 JW4080 | cytoplasmic protein, Alpha-galactosidase MelA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 24 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n7-18c23/24o | Cytoplasmic | 8 | 20 | |||||||||||
| TAUD_ECOLI | P37610 | tauD ssiD yaiG | ssiD yaiG | b0368 JW0360 | cytoplasmic protein, Alpha-ketoglutarate-dependent taurine dioxygenase TauD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.149 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 38 | |||||||||||
| XYLS_ECOLI | P31434 | yicI | b3656 JW3631 | cytoplasmic protein, Alpha-xylosidase YicI | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 25 | 0.174 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 31 | ||||||||||||
| ARFA_ECOLI | P36675 | arfA yhdL | yhdL | b4550 JW3253 | cytoplasmic protein, Alternative ribosome-rescue factor A ArfA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 29 | 0.112 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 135 | |||||||||||
| UXAB_ECOLI | P0A6L7 | uxaB | b1521 JW1514 | cytoplasmic protein, Altronate oxidoreductase UxaB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 64 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 80 | ||||||||||||
| ARGA_ECOLI | P0A6C5 | argA | b2818 JW2786 | cytoplasmic protein, Amino-acid acetyltransferase ArgA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 60 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 57 | |||||||||||
| PHNO_ECOLI | P16691 | phnO | b4093 JW4054 | cytoplasmic protein, Aminoalkylphosphonate N-acetyltransferase PhnO | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 28 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 66 | ||||||||||||
| PABC_ECOLI | P28305 | pabC | b1096 JW1082 | cytoplasmic protein, Aminodeoxychorismate lyase PabC | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 30 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 11 | ||||||||||||
| PABB_ECOLI | P05041 | pabB | b1812 JW1801 | cytoplasmic protein, Aminodeoxychorismate synthase component 1 PabB | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 42 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-12c17/18o | Cytoplasmic | 9 | 82 | ||||||||||||
| PABA_ECOLI | P00903 | pabA | b3360 JW3323 | cytoplasmic protein, Aminodeoxychorismate synthase component 2 PabA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 25 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | |||||||||||||
| YPDE_ECOLI | P77585 | ypdE | b2384 JW2381 | cytoplasmic protein, Aminopeptidase YpdE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 24 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | ||||||||||||
| YPDF_ECOLI | P76524 | ypdF | b2385 JW2382 | cytoplasmic protein, Aminopeptidase YpdF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 19 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 32 | ||||||||||||
| AMN_ECOLI | P0AE12 | amn | b1982 JW1963 | cytoplasmic protein, AMP nucleosidase Amn | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 28 | 0.119 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 37 | ||||||||||||
| NORV_ECOLI | Q46877 | norV flrD ygaI ygaJ ygaK | flrD ygaI ygaJ ygaK | b2710 JW2680 | cytoplasmic protein, Anaerobic nitric oxide reductase flavorubredoxin NorV | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 18 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 39 | ||||||||||
| NRDD_ECOLI | P28903 | nrdD | b4238 JW4197 | cytoplasmic protein, Anaerobic ribonucleoside-triphosphate reductase NrdD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 59 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 59 | ||||||||||||
| NRDG_ECOLI | P0A9N8 | nrdG yjgE | yjgE | b4237 JW4196 | cytoplasmic protein, Anaerobic ribonucleoside-triphosphate reductase-activating NrdG | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 30 | 0.17 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 68 | ||||||||||
| ASLB_ECOLI | P25550 | aslB atsB | atsB | b3800 JW5594 | cytoplasmic protein, Anaerobic sulfatase-maturating enzyme homolog AslB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||||||
| YDEM_ECOLI | P76134 | ydeM | b1497 JW1492 | cytoplasmic protein, Anaerobic sulfatase-maturating enzyme homolog YdeM | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 32 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 7 | ||||||||||||
| ANMK_ECOLI | P77570 | anmK ydhH | ydhH | b1640 JW1632 | cytoplasmic protein, Anhydro-N-acetylmuramic acid kinase AnmK | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 24 | 0.131 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 55 | |||||||||||
| ARPA_ECOLI | P23325 | arpA arp yjaC | arp yjaC | b4017 JW3977 | cytoplasmic protein, Ankyrin repeat A ArpA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 21 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| IRAD_ECOLI | P39375 | iraD yjiD | yjiD | b4326 JW5782 | cytoplasmic protein, Anti-adapter IraD | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 39 | 0.204 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 70 | ||||||||||
| IRAM_ECOLI | P75987 | iraM elb1 elbA ycgW | elb1 elbA ycgW | b1160 JW1147 | cytoplasmic protein, Anti-adapter IraM | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 23 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 54 | ||||||||||
| IRAP_ECOLI | P0AAN9 | iraP yaiB | yaiB | b0382 JW0373 | cytoplasmic protein, Anti-adapter IraP | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 42 | 0.126 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 83 | ||||||||||
| YAFW_ECOLI | Q47684 | yafW | b0246 JW0235 | cytoplasmic protein, Antitoxin YafW | Cytoplasmic | A | A | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | no | no | No | 24 | 0.107 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 14 | |||||||||||
| YFJZ_ECOLI | P52141 | yfjZ | b2645 JW2626 | cytoplasmic protein, Antitoxin YfjZ | Cytoplasmic | A | A | Cytoplasmic | N/A | Prophage Integrase (EcoGene) | no | no | No | 18 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 64 | |||||||||||
| APAG_ECOLI | P62672 | apaG | b0050 JW0049 | cytoplasmic protein, ApaG | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 31 | 0.135 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 67 | ||||||||||||
| CITX_ECOLI | P0A6G5 | citX ybdU | ybdU | b0614 JW0606 | cytoplasmic protein, Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CitX | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 48 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | ||||||||||||
| GUTQ_ECOLI | P17115 | gutQ srlQ | srlQ | b2708 JW5431 | cytoplasmic protein, Arabinose 5-phosphate isomerase GutQ | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 35 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 51 | |||||||||||
| KDSD_ECOLI | P45395 | kdsD yrbH | yrbH | b3197 JW3164 | cytoplasmic protein, Arabinose 5-phosphate isomerase KdsD | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 69 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 62 | |||||||||||
| ASTA_ECOLI | P0AE37 | astA ydjV | ydjV | b1747 JW1736 | cytoplasmic protein, Arginine N-succinyltransferase AstA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 34 | 0.16 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 12 | |||||||||||
| SYR_ECOLI | P11875 | argS | b1876 JW1865 | cytoplasmic protein, Arginine--tRNA ligase ArgS | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 23 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 24 | |||||||||||
| AROM_ECOLI | P0AE28 | aroM | b0390 JW0381 | cytoplasmic protein, AroM | Phobius predicts signal peptide (1-20). | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 24 | 0.115 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-13c20/21o | Cytoplasmic | 8 | 108 | |||||||||||
| TYRB_ECOLI | P04693 | tyrB | b4054 JW4014 | cytoplasmic protein, Aromatic-amino-acid aminotransferase TyrB | Disulfide bond-containing protein PMID: 25664544 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 10 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 38 | ||||||||||
| ARSC_ECOLI | P0AB96 | arsC arsG | arsG | b3503 JW3470 | cytoplasmic protein, Arsenate reductase ArsC | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 14 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 92 | |||||||||||
| PAND_ECOLI | P0A790 | panD | b0131 JW0127 | cytoplasmic protein, Aspartate 1-decarboxylase PanD | Cytoplasmic (Probable) | PMID: 6767707 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 62 | 0.203 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 75 | |||||||||
| PYRB_ECOLI | P0A786 | pyrB | b4245 JW4204 | cytoplasmic protein, Aspartate carbamoyltransferase catalytic subunit PyrB | Trigger factor-sensitive aggregation. | Cytoplasmic | A | A | Cytoplasmic | N/A | TF | yes | yes | No | 34 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 78 | ||||||||||
| PYRI_ECOLI | P0A7F3 | pyrI | b4244 JW4203 | cytoplasmic protein, Aspartate carbamoyltransferase regulatory chain PyrI | Cytoplasmic (Experimental) | PMID: 3912513 PMID: 8740179 | Cytoplasmic | A | A | Cytoplasmic (Experimental) | N/A | yes | yes | No | 37 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 116 | ||||||||||
| ASNA_ECOLI | P00963 | asnA | b3744 JW3722 | cytoplasmic protein, Aspartate--ammonia ligase AsnA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 45 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 90 | |||||||||||
| YGHR_ECOLI | P64572 | yghR | b2984 JW2952 | cytoplasmic protein, ATP-binding YghR | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | no | yes | No | 50 | 0.116 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 31 | |||||||||||
| PFKB_ECOLI | P06999 | pfkB | b1723 JW5280 | cytoplasmic protein, ATP-dependent 6-phosphofructokinase isozyme 2 PfkB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 58 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 83 | ||||||||||||
| CLPS_ECOLI | P0A8Q6 | clpS yljA | yljA | b0881 JW0865 | cytoplasmic protein, ATP-dependent Clp protease adapter ClpS | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 53 | 0.102 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 62 | |||||||||||
| CLPA_ECOLI | P0ABH9 | clpA lopD | lopD | b0882 JW0866 | cytoplasmic protein, ATP-dependent Clp protease ATP-binding subunit ClpA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 18 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 60 | |||||||||||
| CLPX_ECOLI | P0A6H1 | clpX lopC | lopC | b0438 JW0428 | cytoplasmic protein, ATP-dependent Clp protease ATP-binding subunit ClpX | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 31 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 69 | |||||||||||
| CLPP_ECOLI | P0A6G7 | clpP lopP | lopP | b0437 JW0427 | cytoplasmic protein, ATP-dependent Clp protease proteolytic subunit ClpP | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | no | yes | No | 31 | 0.108 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | |||||||||||
| BIOD1_ECOLI | P13000 | bioD1 | b0778 JW0761 | cytoplasmic protein, ATP-dependent dethiobiotin synthetase 1 BioD | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 36 | 0.141 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 27 | |||||||||||
| BIOD2_ECOLI | P0A6E9 | bioD2 ynfK | ynfK | b1593 JW5264 | cytoplasmic protein, ATP-dependent dethiobiotin synthetase 2 BioD | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | yes | yes | No | 32 | 0.161 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 89 | ||||||||||
| DING_ECOLI | P27296 | dinG rarB | rarB | b0799 JW0784 | cytoplasmic protein, ATP-dependent DNA helicase DinG | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 36 | 0.104 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 5 | |||||||||||
| RECQ_ECOLI | P15043 | recQ | b3822 JW5855 | cytoplasmic protein, ATP-dependent DNA helicase RecQ | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 5 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 47 | ||||||||||||
| HSLV_ECOLI | P0A7B8 | hslV htpO yiiC | htpO yiiC | b3932 JW3903 | cytoplasmic protein, ATP-dependent protease subunit HslV | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 30 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | |||||||||||
| HRPB_ECOLI | P37024 | hrpB yadO | yadO | b0148 JW0144 | cytoplasmic protein, ATP-dependent RNA helicase HrpB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 32 | 0.17 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n6-17c26/27o | CytoplasmicMembrane | 9 | 3 | |||||||||||
| RAVA_ECOLI | P31473 | ravA yieN | yieN | b3746 JW3725 | cytoplasmic protein, ATPase RavA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | IM (predicted) | no | yes | No | 69 | 0.182 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 27 | ||||||||||
| LSRK_ECOLI | P77432 | lsrK ydeV | ydeV | b1511 JW1504 | cytoplasmic protein, Autoinducer-2 kinase LsrK | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 27 | 0.149 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 6 | ||||||||||
| FTNA_ECOLI | P0A998 | ftnA ftn gen-165 rsgA | ftn gen-165 rsgA | b1905 JW1893 | cytoplasmic protein, Bacterial non-heme ferritin FtnA | Copurifies with trigger factor in pull down assays. | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 48 | 0.159 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 74 | ||||||||
| BFR_ECOLI | P0ABD3 | bfr | b3336 JW3298 | cytoplasmic protein, Bacterioferritin Bfr | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 30 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 95 | ||||||||||||
| BFD_ECOLI | P0AE56 | bfd yheA | yheA | b3337 JW3299 | cytoplasmic protein, Bacterioferritin-associated ferredoxin Bfd | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 18 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | ||||||||||||
| BAX_ECOLI | P27297 | bax | b3570 JW5653 | cytoplasmic protein, Bax | Potential substrate of periplasmic peptidyl prolyl cis???trans isomerase SurA. Sequence contains known binding motif of SurA [RYEF]X[RYEF][P]. ATP-binding, | Cytoplasmic | A | A | Periplasmic | N/A | SurA | yes | yes | Yes | 28 | 0.533 | SpI | 27 | 13.0141 | - | 0 | 0 | Y | n10-21c27/28o | Unknown | 2 | 60 | ||||||||||
| BDM_ECOLI | P76127 | bdm yddX | yddX | b1481 JW5239 | cytoplasmic protein, Bdm | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 27 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| BEEE_ECOLI | P75980 | beeE ymfO | ymfO | b1151 JW1137 | cytoplasmic protein, BeeE | Cytoplasmic | A | A | Cytoplasmic | N/A | pseudogene (Uniprot) | no | no | No | 57 | 0.129 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 9 | ||||||||||
| BGAL_ECOLI | P00722 | lacZ | b0344 JW0335 | cytoplasmic protein, Beta-galactosidase LacZ | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 36 | 0.136 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 41 | ||||||||||||
| NAGZ_ECOLI | P75949 | nagZ ycfO | ycfO | b1107 JW1093 | cytoplasmic protein, Beta-hexosaminidase NagZ | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 40 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 11 | ||||||||||
| PGMB_ECOLI | P77366 | ycjU | b1317 JW1310 | cytoplasmic protein, Beta-phosphoglucomutase YcjU | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 30 | 0.157 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | ||||||||||||
| COBU_ECOLI | P0AE76 | cobU | b1993 JW1971 | cytoplasmic protein, Bifunctional adenosylcobalamin biosynthesis CobU | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 20 | 0.144 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 62 | ||||||||||||
| PHEA_ECOLI | P0A9J8 | pheA | b2599 JW2580 | cytoplasmic protein, Bifunctional chorismate mutase/prephenate dehydratase PheA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 33 | 0.122 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 44 | |||||||||||
| FOLD_ECOLI | P24186 | folD ads | ads | b0529 JW0518 | cytoplasmic protein, Bifunctional FolD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 49 | 0.145 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 44 | |||||||||||
| GLNE_ECOLI | P30870 | glnE | b3053 JW3025 | cytoplasmic protein, Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GlnE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 33 | 0.21 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 9 | 57 | ||||||||||||
| GSP_ECOLI | P0AES0 | gss gsp | gsp | b2988 JW2956 | cytoplasmic protein, Bifunctional glutathionylspermidine synthetase/amidase Gss | Cytoplasmic | A | A | Membrane anchored | N/A | yes | yes | No | 25 | 0.115 | CYT | 0 | -0.200913 | - | 1 | 0 | N | i | Cytoplasmic | 8 | 50 | |||||||||||
| HLDE_ECOLI | P76658 | hldE rfaE waaE yqiF | rfaE waaE yqiF | b3052 JW3024 | cytoplasmic protein, Bifunctional HldE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 68 | 0.175 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 77 | |||||||||||
| NNR_ECOLI | P31806 | nnr yjeF | yjeF | b4167 JW4125 | cytoplasmic protein, Bifunctional Nnr | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 31 | 0.132 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 53 | |||||||||||
| PAAZ_ECOLI | P77455 | paaZ maoC ydbN | maoC ydbN | b1387 JW1382 | cytoplasmic protein, Bifunctional PaaZ | No transmembrane helix is predicted. Weak hydrophobic and non cytoplasmic regions predicted by Phobius. | Cytoplasmic | A | A | Cytoplasmic | IM (predicted-detected) | no | yes | No | 33 | 0.11 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 8 | ||||||||||
| PUR9_ECOLI | P15639 | purH | b4006 JW3970 | cytoplasmic protein, Bifunctional purine biosynthesis PurH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 27 | 0.151 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 72 | ||||||||||||
| RIBF_ECOLI | P0AG40 | ribF yaaC | yaaC | b0025 JW0023 | cytoplasmic protein, Bifunctional riboflavin kinase/FMN adenylyltransferase RibF | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 65 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 42 | |||||||||||
| SPOT_ECOLI | P0AG24 | spoT | b3650 JW3625 | cytoplasmic protein, Bifunctional SpoT | Cytoplasmic (Probable) | PMID: 17616600 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 69 | 0.124 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 8 | |||||||||
| GLND_ECOLI | P27249 | glnD | b0167 JW0162 | cytoplasmic protein, Bifunctional uridylyltransferase/uridylyl-removing enzyme GlnD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 21 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 8 | |||||||||||||
| ADIA_ECOLI | P28629 | adiA adi | adi | b4117 JW5731 | cytoplasmic protein, Biodegradative arginine decarboxylase AdiA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 21 | 0.114 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 30 | ||||||||||
| BSSR_ECOLI | P0AAY1 | bssR yliH | yliH | b0836 JW0820 | cytoplasmic protein, Biofilm regulator BssR | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 23 | 0.138 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 51 | |||||||||||
| BSSS_ECOLI | P0AB33 | bssS yceP | yceP | b1060 JW5152 | cytoplasmic protein, Biofilm regulator BssS | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 39 | 0.109 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 88 | |||||||||||
| BCCP_ECOLI | P0ABD8 | accB fabE | fabE | b3255 JW3223 | cytoplasmic protein, Biotin carboxyl carrier of acetyl-CoA carboxylase AccB | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 50 | 0.616 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 95 | |||||||||||
| BISC_ECOLI | P20099 | bisC | b3551 JW5940 | cytoplasmic protein, Biotin sulfoxide reductase BisC | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 24 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Periplasmic | 9 | |||||||||||||
| BIOB_ECOLI | P12996 | bioB | b0775 JW0758 | cytoplasmic protein, Biotin synthase BioB | Cytoplasmic | A | A | Cytoplasmic | IM (predicted) | yes | yes | No | 33 | 0.13 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 58 | ||||||||||||
| APAH_ECOLI | P05637 | apaH | b0049 JW0048 | cytoplasmic protein, Bis(5'-nucleosyl)-tetraphosphatase ApaH | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 29 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 27 | ||||||||||||
| BLUF_ECOLI | P75990 | bluF blrp ycgF | blrp ycgF | b1163 JW1150 | cytoplasmic protein, Blue light- and temperature-regulated antirepressor BluF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 49 | 0.111 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 7 | 20 | |||||||||||
| ILVE_ECOLI | P0AB80 | ilvE | b3770 JW5606 | cytoplasmic protein, Branched-chain-amino-acid aminotransferase IlvE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 39 | 0.117 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 30 | ||||||||||||
| ARCC_ECOLI | P37306 | arcC ybcF | ybcF | b0521 JW0510 | cytoplasmic protein, Carbamate kinase ArcC | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.244 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n3-14c19/20o | Cytoplasmic | 9 | 16 | ||||||||||
| ARCL_ECOLI | Q46807 | yqeA | b2874 JW2842 | cytoplasmic protein, Carbamate kinase-like YqeA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 20 | 0.148 | SpI | 15 | 2.26791 | - | 0 | 0 | Y | n5-10c15/16o | Cytoplasmic | 9 | 97 | ||||||||||||
| HYPE_ECOLI | P24193 | hypE | b2730 JW2700 | cytoplasmic protein, Carbamoyl dehydratase HypE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 34 | 0.256 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 24 | ||||||||||||
| HYPF_ECOLI | P30131 | hypF hydA | hydA | b2712 JW5433 | cytoplasmic protein, Carbamoyltransferase HypF | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 20 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 8 | 73 | |||||||||||
| CSRA_ECOLI | P69913 | csrA zfiA | zfiA | b2696 JW2666 | cytoplasmic protein, Carbon storage regulator CsrA | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | no | yes | No | 37 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | |||||||||||
| CYNT_ECOLI | P0ABE9 | cynT | b0339 JW0330 | cytoplasmic protein, Carbonic anhydrase 1 CynT | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 46 | 0.101 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 46 | ||||||||||||
| CAN_ECOLI | P61517 | can cynT2 yadF | cynT2 yadF | b0126 JW0122 | cytoplasmic protein, Carbonic anhydrase 2 Can | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 33 | 0.123 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 47 | |||||||||||
| CMOA_ECOLI | P76290 | cmoA yecO | yecO | b1870 JW1859 | cytoplasmic protein, Carboxy-S-adenosyl-L-methionine synthase CmoA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 57 | 0.118 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 32 | |||||||||||
| CLSC_ECOLI | P75919 | clsC ymdC | ymdC | b1046 JW5150 | cytoplasmic protein, Cardiolipin synthase C ClsC | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 33 | 0.304 | CYT | 0 | -0.200913 | - | 0 | 0 | Y | n4-12c19/20o | CytoplasmicMembrane | 9 | 21 | |||||||||||
| CNTA_ECOLI | P0ABR7 | yeaW | b1802 JW5294 | cytoplasmic protein, Carnitine monooxygenase oxygenase subunit YeaW | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 60 | 0.271 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 107 | ||||||||||||
| CNTB_ECOLI | P76254 | yeaX | b1803 JW1792 | cytoplasmic protein, Carnitine monooxygenase reductase subunit YeaX | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 58 | 0.134 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 71 | ||||||||||||
| CAIE_ECOLI | P39206 | caiE | b0035 JW5004 | cytoplasmic protein, Carnitine operon CaiE | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 27 | 0.148 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 18 | ||||||||||||
| CAID_ECOLI | P31551 | caiD yaaL | yaaL | b0036 JW0035 | cytoplasmic protein, Carnitinyl-CoA dehydratase CaiD | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 26 | 0.176 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 15 | |||||||||||
| CATE_ECOLI | P21179 | katE | b1732 JW1721 | cytoplasmic protein, Catalase KatE | Trigger factor-sensitive aggregation. | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | TF | yes | yes | No | 48 | 0.103 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 43 | |||||||||
| KATG_ECOLI | P13029 | katG | b3942 JW3914 | cytoplasmic protein, Catalase-peroxidase KatG | Trigger factor-sensitive aggregation. | Cytoplasmic | A | A | Cytoplasmic | N/A | TF | yes | yes | No | 30 | 0.121 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 84 | ||||||||||
| CBRA_ECOLI | P31456 | cbrA yidS | yidS | b3690 JW5631 | cytoplasmic protein, CbrA | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 20 | 0.273 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 34 | |||||||||||
| CEDA_ECOLI | P0AE60 | cedA ydjP | ydjP | b1731 JW1720 | cytoplasmic protein, Cell division activator CedA | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 61 | 0.153 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 107 | |||||||||||
| SULA_ECOLI | P0AFZ5 | sulA sfiA | sfiA | b0958 JW0941 | cytoplasmic protein, Cell division inhibitor SulA | Cytoplasmic (Probable) | SulA halts cell division in Escherichia coli by binding to the major component of the division machinery FtsZ. | PMID: 12808143 | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 40 | 0.133 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | CytoplasmicMembrane | 10 | 61 | ||||||||
| ZAPC_ECOLI | P75862 | zapC ycbW | ycbW | b0946 JW5125 | cytoplasmic protein, Cell division ZapC | Cytoplasmic (Probable) | ZapC is a stabilizer of the FtsZ ring. | PMID: 21216995 PMID: 21216997 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 36 | 0.113 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 37 | |||||||
| ZAPE_ECOLI | P64612 | zapE yhcM | yhcM | b3232 JW3201 | cytoplasmic protein, Cell division ZapE | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic | N/A | yes | yes | No | 22 | 0.106 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 31 | ||||||||||
| YBBN_ECOLI | P77395 | ybbN | b0492 JW5067 | cytoplasmic protein, Chaperedoxin YbbN | Cytoplasmic | A | A | Cytoplasmic | N/A | no | yes | No | 50 | 0.128 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 9 | 75 | ||||||||||||
| CBPM_ECOLI | P63264 | cbpM yccD | yccD | b0999 JW0984 | cytoplasmic protein, Chaperone modulator CbpM | Cytoplasmic | A | A | Cytoplasmic | N/A | yes | yes | No | 22 | 0.105 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Unknown | 2 | 35 | |||||||||||
| NAPD_ECOLI | P0A9I5 | napD yojF | yojF | b2207 JW2195 | cytoplasmic protein, Chaperone NapD | Cytoplasmic (Experimental) | NapD is a Tat signal peptide-binding chaperone involved in biosynthesis of the Tat-dependent nitrate reductase NapA. PMID: 17074894 | PMID: 17074894 | Cytoplasmic | A | A | Cytoplasm | Cytoplasmic (Experimental) | N/A | yes | yes | No | 29 | 0.151 | CYT | 0 | -0.200913 | - | 0 | 0 | N | i | Cytoplasmic | 10 | 108 | |||||||
| TORD |