STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli K-12
(reference proteome)
E.coli BL21(DE3)
 K-12 vs BL21(DE3) E.coli EPEC (O127:H6)
1) PROTEOME INFORMATION
Proteome and Sequence Information
Protein location and pseudogenes - - -
Core Proteome i - - -
Basic Proteome i - - -
Complexome - - -
Disulfideome - - -
Protein characteristics - - -
Protein Concentration - - -
Change in protein abundance in different media - - -
2) PROTEIN SUBCELLULAR LOCATIONS
Peripherome - -
Exportome i - -
Signal Peptides list - - -
Membranome i - -
a) Tail-Anchored Inner Membrane Protein (TAMPs) - - -
b) Sec i - - -
c) Tat i - - -
Secretome i - -
a) Sec i - - -
b) Tat i - - -
c) Non-classical i - - -
Proteins with multiple topologies - -
Proteins with longitudinal positioning - - -
Sec secretory proteins with short mature domains - - -
Colicins - - -
3) PROTEOSTATIC MACHINERIES
Chaperonome - - -
Chaperone interactors - - -
Proteaseome - - -
4) PROTEIN PROPERTIES AND REGIONS
Early Foldons (EFoldMine) - - -
Intrinsically disordered regions (IUPred2) - - -
Hydrophobic regions (Kyte&Doolittle scale) - - -
Aggregation Prone Regions (TANGO) - - -
Protein regions (foldons, IDRs, hydrophobic regions, APRs) - - -
5) PROTEIN PROPERTIES CROSS-COMPARISSION PLOTS (Backbone dynamics, Early folding, Disorder and Hydrophobicity)
Cytoplasmic proteins - - -
Cytoplasmic ribosomal proteins - - -
Integral Inner Membrane proteins - - -
Secreted proteins - - -
Secreted Outer Membrane proteins - - -
6) STRUCTUROME
Reference structures (experimental and models) - - -
Proteins missing structures - - -
Foldome - - -
7) TYPE III SECRETION SYSTEM
Flagellum proteins - - -
Injectisome proteins - - -
T3SS homologues - - -
8) REFERENCES AND UPDATES
Experimentally verified topologies - - -
References - - -
Changes from STEPdb1.0 to STEPdb2.0 - - -
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 ©2017 Copyright KU Leuven and FORTH/ICE-HT. Last Update: February 2019.