STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

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E.coli BL21(DE3) proteome

(mouse over and click on the one letter topology symbols to see which proteins of this specific subproteome are localized in each location)

Bacterial cell cartoon of sub-cellular locations


Protein ID
(Uniprot)
Accession
(Uniprot)
Gene Name
Order Locus Name
Protein Name
(STEPdb)
Full Name
Symbol
Uniprot
First Level
Secretion
System
First Level
Targeting
Chaperoning
Second Level
Secretion
System
Second Level
Targeting
Chaperoning
E.coli Core
Proteome
(yes/no)
basic proteome
C6EB73_ECOBD
C6EB73
dacD
B21_01899 ECBD_1647 ECD_01913
D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein 6b) (EC 3.4.16.4) (Serine-type D-Ala-D-Ala carboxypeptidase) (EC 3.4.16.4)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
 
yes
C6EBC8_ECOBD
C6EBC8
fliE
ECBD_1708
Flagellar hook-basal body complex protein fliE
Extrinsic to external side of plasma membrane
F2
Bacterial flagellum basal body
SEC
SRP
 
 
 
yes
C6EBZ9_ECOBD
C6EBZ9
prc
B21_01789 ECBD_1810 ECD_01801
Carboxy-terminal protease for penicillin-binding protein 3 (EC 3.4.21.-) (Carboxyl-terminal protease) (EC 3.4.21.102)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EDN4_ECOBD
C6EDN4
ydgA
B21_01573 ECBD_2032 ECD_01583
Putative uncharacterized protein (Putative uncharacterized protein ydgA)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EEY4_ECOBD
C6EEY4
cpxP
B21_03748 ECBD_4110 ECD_03799
Periplasmic protein combats stress (Putative uncharacterized protein)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
 
yes
C6EH45_ECOBD
C6EH45
dacB
B21_02998 ECBD_0560 ECD_03047
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) (D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase) (EC 3.4.16.4)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EIU4_ECOBD
C6EIU4
dacC
B21_00823 ECBD_2784 ECD_00806
Beta-lactamase (EC 3.5.2.6) (D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein 6a)) (EC 3.4.16.4)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EJB4_ECOBD
C6EJB4
iap
B21_02568 ECBD_0971 ECD_02603
Aminopeptidase in alkaline phosphatase isozyme conversion (EC 3.4.11.-) (Peptidase M28)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EK61_ECOBD
C6EK61
dacA
B21_00590 ECBD_3019 ECD_00601
Beta-lactamase (EC 3.5.2.6) (D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein 5)) (EC 3.4.16.4)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EKC7_ECOBD
C6EKC7
cusB
B21_00524 ECBD_3088 ECD_00535
Copper/silver efflux system, membrane fusion protein (Efflux transporter, RND family, MFP subunit)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EAN1_ECOBD
C6EAN1
mdtA

yegM
B21_01971 ECBD_1579 ECD_01979
Multidrug resistance protein mdtA (Multidrug transporter mdtA)
Extrinsic to external side of plasma membrane
F2
Cell inner membrane | Peripheral membrane protein
SEC
 
 
 
yes
yes
C6EAS7_ECOBD
C6EAS7
yadE
B21_00128 ECBD_3489 ECD_00129
Polysaccharide deacetylase (Predicted polysaccharide deacetylase lipoprotein)
Extrinsic to external side of plasma membrane
F2
 
SEC
 
 
 
yes
yes
C6EB73_ECOBD
C6EB73
dacD
B21_01899 ECBD_1647 ECD_01913
D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein 6b) (EC 3.4.16.4) (Serine-type D-Ala-D-Ala carboxypeptidase) (EC 3.4.16.4)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
 
yes
C6EBC8_ECOBD
C6EBC8
fliE
ECBD_1708
Flagellar hook-basal body complex protein fliE
Peripheral inner membrane protein facing the periplasm
F2
Bacterial flagellum basal body
SEC
SRP
 
 
 
yes
C6EBZ9_ECOBD
C6EBZ9
prc
B21_01789 ECBD_1810 ECD_01801
Carboxy-terminal protease for penicillin-binding protein 3 (EC 3.4.21.-) (Carboxyl-terminal protease) (EC 3.4.21.102)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
yes
yes
C6EDN4_ECOBD
C6EDN4
ydgA
B21_01573 ECBD_2032 ECD_01583
Putative uncharacterized protein (Putative uncharacterized protein ydgA)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
yes
yes
C6EEY4_ECOBD
C6EEY4
cpxP
B21_03748 ECBD_4110 ECD_03799
Periplasmic protein combats stress (Putative uncharacterized protein)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
 
yes
C6EH45_ECOBD
C6EH45
dacB
B21_02998 ECBD_0560 ECD_03047
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) (D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase) (EC 3.4.16.4)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
yes
yes
C6EIU4_ECOBD
C6EIU4
dacC
B21_00823 ECBD_2784 ECD_00806
Beta-lactamase (EC 3.5.2.6) (D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein 6a)) (EC 3.4.16.4)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
yes
yes
C6EJB4_ECOBD
C6EJB4
iap
B21_02568 ECBD_0971 ECD_02603
Aminopeptidase in alkaline phosphatase isozyme conversion (EC 3.4.11.-) (Peptidase M28)
Peripheral inner membrane protein facing the periplasm
F2
 
SEC
 
 
 
yes
yes
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 ©2017 Copyright KU Leuven and FORTH/ICE-HT. Last Update: February 2019.