STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

MatureP

Sequence Upload (fasta format):

MatureP is a tool that predicts Sec secretory vs cytoplasmic proteins. Two methods are availiable: MatureP and SP-MatureP (explain). When MatureP method is selected only the mature sequence must be provided whereas when SP-MatureP method is selected both the pre-protein and the mature domain sequences are applicaple. We recommend that you provide at least 100 amino acids per sequence since all models were trained using the first 100 aas of each sequence. Alternatively, please load a fasta file below.

or upload a fasta file:

Select a file to upload:

Alternatively try:

Sequence similarity search:

Search for homologous sequences within the E. coli K-12 proteome and view potential topologies of your sequence.

BLAST2STEP

Datasets:

The datasets used for training, testing and validation of the MatureP classifier are available for download.

Datasets